Abstract:
:Early detection of a premalignant or cancerous oral lesion promises to improve the survival and the morbidity of patients suffering from these conditions. Cytological study of oral cells is a non-aggressive technique that is well accepted by the patient, and is therefore an attractive option for the early diagnosis of oral cancer, including epithelial atypia and squamous cell carcinoma. However its usage has been limited so far due to poor sensitivity and specificity in diagnosing oral malignancies. Lately it has re-emerged due to improved methods and it's application in oral precancer and cancer as a diagnostic and predictive method as well as for monitoring patients. Newer diagnostic techniques such as "brush biopsy" and molecular studies have been developed. Recent advances in cytological techniques and novel aspects of applications of scraped or exfoliative cytology for detecting these lesions and predicting their progression or recurrence are reviewed here.
journal_name
Mol Cancerjournal_title
Molecular cancerauthors
Mehrotra R,Gupta A,Singh M,Ibrahim Rdoi
10.1186/1476-4598-5-11keywords:
subject
Has Abstractpub_date
2006-03-23 00:00:00pages
11issn
1476-4598pii
1476-4598-5-11journal_volume
5pub_type
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