Impairment of granulation tissue formation after menopause.

abstract：:Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is an inherited disease which may comprise many endocrine and non-endocrine components. GH insufficiency has not been recognised as a classical manifestation of this syndrome. We describe the case of a girl with APECED, who presented with four end...

journal_title：Journal of endocrinological investigation

authors： Franzese A,Valerio G,Di Maio S,Iannucci MP,Bloise A,Tenore A

更新日期：1999-01-01 00:00:00

abstract：:A 39-year-old Danish woman was treated with an oral dose of 400 MBq 131I for a non-toxic goiter with compression symptoms. Serum anti-TPO and TSH receptor antibodies were negative before radioiodine therapy. The patient developed hyperthyroidism four months after treatment and ophthalmopathy after another three months...

journal_title：Journal of endocrinological investigation

authors： Nygaard B,Metcalfe RA,Phipps J,Weetman AP,Hegedüs L

更新日期：1999-06-01 00:00:00

abstract：:Pathogenesis of idiopathic diabetes insipidus is unknown and the clinical course of the disease is permanent. However, we observed one patient who was diagnosed of idiopathic diabetes insipidus spontaneously reverted after approximately 13 months. The cause and pathogenesis of the disease were not evident. However, so...

journal_title：Journal of endocrinological investigation

authors： Ohshima K,Okada S,Onai T,Umahara M,Mori M,Kobayashi I,Kobayashi S,Katakai S

更新日期：1989-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the hypothesis that interleukin-1beta (IL-1beta) might be involved in the increase of the circulating levels of placental-derived CRH leading to the initiation of pre-term labor. SUBJECTS AND METHODS:Forty-eight primigravidae with a singleton viable pregnancy between ...

journal_title：Journal of endocrinological investigation

authors： Vitoratos N,Mastorakos G,Kountouris A,Papadias K,Creatsas G

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The significance of vitamin D deficiency in the incidence of bone fractures in children has been under investigated. Here, we aimed to associate serum 25-hydroxyvitamin D levels and fractures in Saudi children. MATERIALS AND METHODS:This cross-sectional study was conducted in 1022 Saudi children without fra...

journal_title：Journal of endocrinological investigation

authors： Al-Daghri NM,Aljohani N,Rahman S,Sabico S,Al-Attas OS,Alokail MS,Al-Ajlan A,Chrousos GP

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Protein tyrosine phosphatase (PTP)- 1B, encoded by the PTPN1 gene, negatively regulates insulin signaling by dephosphorylating the phosphotyrosine residues of the insulin receptor kinase activation segment. Several rare single nucleotide polymorphisms (SNP) have been linked to diseases accompanying insulin r...

journal_title：Journal of endocrinological investigation

authors： Gu P,Jiang W,Du H,Shao J,Lu B,Wang J,Zou D

更新日期：2010-07-01 00:00:00

abstract：:We herein describe a family with thyroid hormone resistance. Thyroid hormones and basal TSH were elevated. Pituitary tumor or abnormality in thyroid hormone binding proteins were ruled out by appropriate tests. Mother and sister of the propositus presented similar abnormal hormonal features but no hyperthyroidism. Ini...

journal_title：Journal of endocrinological investigation

authors： Aguilar Diosdado M,Escobar-Jimenez L,Fernandez Soto ML,Garcia Curiel A,Escobar-Jimenez F

更新日期：1991-09-01 00:00:00

abstract：:Many studies have shown that fat distribution influences metabolism independently of the effects of total body fat stores. The accumulation of fat in the abdominal area, particularly in the visceral fat compartment, seems to be associated with an increased risk to display complications such as insulin resistance, diab...

journal_title：Journal of endocrinological investigation

authors： Gasteyger C,Tremblay A

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Studies from every continent have shown that only around 50% of the patients subjected to thyroid hormone replacement have TSH in the normal range. However, to date, there are no consistent data about Brazil. OBJECTIVES:To evaluate levothyroxine (LT4) replacement treatment in patients with primary hypothyro...

journal_title：Journal of endocrinological investigation

authors： Vaisman F,Coeli CM,Ward LS,Graf H,Carvalho G,Montenegro R Jr,Vaisman M

更新日期：2013-07-01 00:00:00

abstract：:A 33-year-old female presented in 1966 with striking pigmentation, typical of Addison's disease, and amenorrhea. Endocrine assessment then showed normal basal serum cortisol and urinary hydroxysteroid levels, but serum cortisol did not respond to stimulation with either exogenous ACTH or lysine vasopressin. Steroid re...

journal_title：Journal of endocrinological investigation

authors： Whitehead EM,Atkinson AB,Hadden DR,Weaver J,Sheridan B

更新日期：1989-03-01 00:00:00

abstract：:Eighteen patients affected by laparoscopically confirmed endometriosis were randomly assigned to three different schedules of treatment with gonadotropin-releasing hormone agonist (GnRH-a) (goserelin depot formulation 3.6 mg) every 28 days for 6 months. Six women received the first implant in early follicular phase, 4...

journal_title：Journal of endocrinological investigation

authors： Magini A,Pellegrini S,Tavella K,Forti G,Massi GB,Serio M

更新日期：1993-11-01 00:00:00

abstract：:17alpha-hydroxylase deficiency (17alpha-OHDS) results in decreased production of cortisol and sex steroids and hypokalemia secondary to excess mineralocorticoids. It has long been known that glucocorticoid deficiency is associated with impaired urinary dilution and increased secretion of vasopressin (AVP). On the othe...

journal_title：Journal of endocrinological investigation

authors： Leal AM,Elias PC,Moreira AC

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Depressive disorder encompasses a wide spectrum of somatic and psychological symptoms. It is not known whether there are differences regarding the cluster of depressive symptomatology between subjects with depression with and without T2DM. PURPOSE:To explore whether the cluster of depression that prevails a...

journal_title：Journal of endocrinological investigation

authors： Nicolau J,Simó R,Conchillo C,Sanchís P,Blanco J,Romerosa JM,Fortuny R,Bonet A,Masmiquel L

更新日期：2019-08-01 00:00:00

abstract：:Prolactin, growth hormone and thyroid stimulating hormone responses to thyrotropin releasing hormone (TRH) and metoclopramide were determined in 12 alcoholic men with biopsy proven liver disease and were compared to those of 8 age matched normal controls. All subjects were challenged with TRH (400 micrograms) and meto...

journal_title：Journal of endocrinological investigation

authors： Van Thiel DH,Gavaler JS,Sanghvi A

更新日期：1982-09-01 00:00:00

abstract：OBJECTIVE:Subcutaneous insulin absorption is one of the key factors affecting glycemic control in patients with diabetes mellitus under insulin therapy. Insulin-induced subcutaneous lipohypertrophy has been reported to impair insulin regular absorption and hence glycemic control. So far, lipohypertrophy diagnosis has o...

journal_title：Journal of endocrinological investigation

authors： Bertuzzi F,Meneghini E,Bruschi E,Luzi L,Nichelatti M,Epis O

更新日期：2017-10-01 00:00:00

abstract：:Up to now, the diagnosis of silent corticotroph cell pituitary adenomas has been made only on histopathological basis. In this paper we describe 6 women affected with pituitary adenomas, without evident clinical features of hypercortisolism, in whom retrospective data suggested the possibility of clinically diagnosing...

journal_title：Journal of endocrinological investigation

authors： Ambrosi B,Colombo P,Bochicchio D,Bassetti M,Masini B,Faglia G

更新日期：1992-06-01 00:00:00

abstract：:The study was conducted to assess the GH-IGF-I axis in non-obese women with functional hyperandrogenism (FH). Eighteen FH women aged 18-35 yr with a body weight within 20% of ideal body weight and 10 weight-matched controls were included in the study. Basal serum GH, GH-binding protein (GHBP), IGF-I, IGF-binding prote...

journal_title：Journal of endocrinological investigation

authors： Legan M,Kocijancic A,Prezelj J,Osredkar J,Fisker S

更新日期：2002-09-01 00:00:00

abstract：:The differential diagnosis of an osteoblastic vertebral lesion (ivory vertebra) includes metastatic prostate cancer, lung cancer, lymphoma, osteosarcoma and Paget's disease. We report a case of a man who was initially diagnosed with Paget's disease on vertebral biopsy. He failed to respond to conventional bisphosphate...

journal_title：Journal of endocrinological investigation

authors： Basaria S,McCarthy EF,Belzberg AJ,Ball DW

更新日期：2000-09-01 00:00:00

abstract：:Serial weekly serum samples (for 3 weeks) were obtained from 42 patients with differentiated thyroid cancer (DTC, papillary no.=35, follicular no.=6, Hurthle cell no.=1) for serum thyroid hormone, TSH and TG before and after total thyroidectomy. Serum specimens were also obtained one month after radioiodine (131I) the...

journal_title：Journal of endocrinological investigation

authors： Lima N,Cavaliere H,Tomimori E,Knobel M,Medeiros-Neto G

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:In the mountainous areas of Azerbaijan the schoolchildren suffer from severe Iodine Deficiency (ID) with median Urinary iodine excretion (UIE) 36 mcg/l and prevalence of goiter 99% (estimated by US). In a population of 293,000 schoolchildren aged 8-14 y.o. we administered capsules containing 190 mg of iodized...

journal_title：Journal of endocrinological investigation

authors： Markou KB,Georgopoulos NA,Makri M,Vlasopoulou B,Anastasiou E,Vagenakis GA,Kouloubi K,Theodosopoulos N,Lazarou N,Veizis A,Sakellaropoulos G,Vagenakis AG

更新日期：2003-01-01 00:00:00

abstract：:To assess the role of the renin-angiotensin system in the control of aldosterone reease in response to heat exposure, 6 sodium restricted subjects were studied on three random experimental days: a control day and two heat exposure days (46C, 35 mbar, 90 min) with and without propranolol. Plasma aldosterone, renin acti...

journal_title：Journal of endocrinological investigation

authors： Brandenberger G,Follenius M,Oyono S

更新日期：1980-10-01 00:00:00

abstract：:A comparison of peripheral patterns of androstenedione (A), 17 beta-estradiol (E2) and progesterone (P) is reported in ten infertile women during HMG-HCG induction of ovulation, in order to assess the site of ovarian secretion of plasma A and the possible influence on conception. Evidence for both the follicular and l...

journal_title：Journal of endocrinological investigation

authors： Scirpa P,Mango D,Montemurro A,Battaglia F,Cantafio L

更新日期：1984-08-01 00:00:00

abstract：:The changes occurring in the levels of circulating thyroid microsomal antibody (M-Ab) and antithyroglobulin antibody (Tg-Ab) during antithyroid drug therapy were studied in 32 patients receiving methimazole for Graves' disease. M-Ab was determined by competitive binding radioassay and Tg-Ab by a sandwich radiometric m...

journal_title：Journal of endocrinological investigation

authors： Marcocci C,Chiovato L,Mariotti S,Pinchera A

更新日期：1982-01-01 00:00:00

abstract：:Pheochromocytoma (PHEO) occasionally associates with pathological lesions of the adrenal cortex. In most of them, ectopic adrenocorticotropic hormone (ACTH) produced by PHEO resulted in bilateral adrenocortical hyperplasia. The coexistence of PHEO and pre-clinical Cushing's syndrome (PCS) of the same adrenal gland has...

journal_title：Journal of endocrinological investigation

authors： Erem C,Hacihasanoglu A,Ersöz HO,Reis AK,Calik A,Ukinç K,Koçak M

更新日期：2005-06-01 00:00:00

abstract：:Basal IGF-I levels and the GH response to at least two among provocative stimuli such as clonidine (CLO, Catapresan, 150 mcg/m2 p.o.), GHRH (1 mcg/kg i.v.)+arginine (ARG, 0.5 g/kg i.v. infusion during 30 min) and GHRH+pyridostigmine (PD, Mestinon cpr 60 mg p.o.) have been evaluated in 43 children with Prader-Willi syn...

journal_title：Journal of endocrinological investigation

authors： Corrias A,Bellone J,Beccaria L,Bosio L,Trifirò G,Livieri C,Ragusa L,Salvatoni A,Andreo M,Ciampalini P,Tonini G,Crinò A

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:We aimed to investigate the differences in emotional and behavioral problems and to explore the association between the level of psychiatric problems and the metabolic control in Type 1 diabetes. METHODS:The children with Type 1 diabetes (no.=42) and the "healthy" control group (no.=42), their parents and en...

journal_title：Journal of endocrinological investigation

authors： Akbaş S,Karabekiroğlu K,Ozgen T,Tasdemir G,Karakurt M,Senses A,Böke O,Aydin M

更新日期：2009-04-01 00:00:00

abstract：:Although adjustments to nutritional lifestyle and increased physical activity remain the milestones of weight loss therapy, it is evident from the exponential increase of the number of obese subjects in Western countries that these two approaches alone are no longer able to limit this progression. This alarming phenom...

journal_title：Journal of endocrinological investigation

authors： Pagotto U,Pasquali R

更新日期：2006-01-01 00:00:00

abstract：:Somatostatin and its derivatives have been predominantly studied and succesfully used in endocrinological diseases. This article reviews the rationale of the use of somatostatin and its derivatives in ophthalmology based on current understanding of its action in the eye and summarizes previously published controlled s...

journal_title：Journal of endocrinological investigation

authors： Missotten T,Baarsma GS,Kuijpers RW,van den Born LI,van der Loos T,Croxen R,Hofland LJ,van Hagen PM

更新日期：2005-01-01 00:00:00

abstract：:Abnormalities of the gene encoding the sequence-specific DNA-binding protein, nuclear phosphorprotein p53, are among the most common genetic alterations observed in human cancers. A mutation of this tumor suppressor gene has been reported with a low prevalence in differentiated thyroid carcinomas, while the prevalence...

journal_title：Journal of endocrinological investigation

authors： Iyota K,Takeda K,Matsuzuka F,Okabayashi T,Morita S,Kuma K,Hashimoto K

更新日期：1994-11-01 00:00:00

abstract：:Established methods for definitive ablation of autonomous thyroid nodules are surgery and radioiodine. Since it has been demonstrated that percutaneous ethanol injection can inactivate parathyroid adenomas and small hepatocellular carcinomas, we started a trial of this treatment in patients with autonomous thyroid nod...

journal_title：Journal of endocrinological investigation

authors： Paracchi A,Ferrari C,Livraghi T,Reschini E,Macchi RM,Bergonzi M,Raineri P

更新日期：1992-05-01 00:00:00