The addition of locust bean gum but not water delayed the gastric emptying rate of a nutrient semisolid meal in healthy subjects.

Abstract:

BACKGROUND:Most of the previous studies regarding the effects of gel-forming fibres have considered the gastric emptying of liquid or solid meals after the addition of pectin or guar gum. The influence of locust bean gum, on gastric emptying of nutrient semisolid meals in humans has been less well studied, despite its common occurrence in foods. Using a standardised ultrasound method, this study was aimed at investigating if the gastric emptying in healthy subjects could be influenced by adding locust been gum, a widely used thickening agent, or water directly into a nutrient semisolid test meal. METHODS:The viscosity of a basic test meal (300 g rice pudding, 330 kcal) was increased by adding Nestargel (6 g, 2.4 kcal), containing viscous dietary fibres (96.5%) provided as seed flour of locust bean gum, and decreased by adding 100 ml of water. Gastric emptying of these three test meals were evaluated in fifteen healthy non-smoking volunteers, using ultrasound measurements of the gastric antral area to estimate the gastric emptying rate (GER). RESULTS:The median value of GER with the basic test meal (rice pudding) was estimated at 63%, (range 47 to 84%), (the first quartile = 61%, the third quartile = 69%). Increasing the viscosity of the rice pudding by adding Nestargel, resulted in significantly lower gastric emptying rates (p < 0.01), median GER 54%, (range 7 to 71%), (the first quartile = 48%, the third quartile = 60%). When the viscosity of the rice pudding was decreased (basic test meal added with water), the difference in median GER 65%, (range 38 to 79%), (the first quartile = 56%, the third quartile = 71%) was not significantly different (p = 0.28) compared to the GER of the basic test meal. CONCLUSIONS:We conclude that the addition of locust bean gum to a nutrient semisolid meal has a major impact on gastric emptying by delaying the emptying rate, but that the addition of water to this test meal has no influence on gastric emptying in healthy subjects.

journal_name

BMC Gastroenterol

journal_title

BMC gastroenterology

authors

Darwiche G,Björgell O,Almér LO

doi

10.1186/1471-230X-3-12

keywords:

subject

Has Abstract

pub_date

2003-06-06 00:00:00

pages

12

issn

1471-230X

journal_volume

3

pub_type

杂志文章
  • Unusual manifestation of Erdheim-Chester disease.

    abstract:BACKGROUND:Erdheim-Chester disease (ECD) is a rare multisystem non-Langerhans cell histiocytosis that is characterized histologically by xanthogranulomatous infiltrates and radiologically by symmetrical sclerosis of long bones. The xanthomatous process is characterized by prominent foamy histiocytes staining positive f...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/1471-230X-11-77

    authors: Pan A,Doyle T,Schlup M,Lubcke R,Schultz M

    更新日期:2011-06-22 00:00:00

  • Cognitive-behavioural therapy has no effect on disease activity but improves quality of life in subgroups of patients with inflammatory bowel disease: a pilot randomised controlled trial.

    abstract:BACKGROUND:Studies have demonstrated usefulness of cognitive-behavioural therapy (CBT) in managing distress in inflammatory bowel disease (IBD); however, few have focused on IBD course. The present trial aimed to investigate whether adding CBT to standard treatment prolongs remission in IBD in comparison to standard th...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12876-015-0278-2

    authors: Mikocka-Walus A,Bampton P,Hetzel D,Hughes P,Esterman A,Andrews JM

    更新日期:2015-05-02 00:00:00

  • The association between inflammatory potential of diet and disease activity: results from a cross-sectional study in patients with inflammatory bowel disease.

    abstract:BACKGROUND:Diet may play a role in disease status in patients with inflammatory bowel disease. We tested whether the inflammatory potential of diet, based on a summation of pro- and anti-inflammatory nutrients, is associated with disease activity in patients with Crohn's disease and ulcerative colitis. METHODS:Partici...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/s12876-020-01435-4

    authors: Lamers CR,de Roos NM,Witteman BJM

    更新日期:2020-09-29 00:00:00

  • Plastic or metal stents for benign extrahepatic biliary strictures: a systematic review.

    abstract:BACKGROUND:Benign biliary strictures may be a consequence of surgical procedures, chronic pancreatitis or iatrogenic injuries to the ampulla. Stents are increasingly being used for this indication, however it is not completely clear which stent type should be preferred. METHODS:A systematic review on stent placement f...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1186/1471-230X-9-96

    authors: van Boeckel PG,Vleggaar FP,Siersema PD

    更新日期:2009-12-17 00:00:00

  • Tuberous Sclerosis Complex with rare associated findings in the gastrointestinal system: a case report and review of the literature.

    abstract:BACKGROUND:Tuberous Sclerosis Complex (TSC) is a complex and heterogeneous genetic disease that has well-established clinical diagnostic criteria. These criteria do not include gastrointestinal tumors. CASE PRESENTATION:We report a 45-year-old patient with a clinical and molecular diagnosis of TSC and a family history...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/s12876-020-01481-y

    authors: Reis LB,Konzen D,Netto CBO,Braghini PMB,Prolla G,Ashton-Prolla P

    更新日期:2020-11-23 00:00:00

  • Diffuse duodenal nodular lymphoid hyperplasia: a large cohort of patients etiologically related to Helicobacter pylori infection.

    abstract:BACKGROUND:Nodular lymphoid hyperplasia of gastrointestinal tract is a rare disorder, often associated with immunodeficiency syndromes. There are no published reports of its association with Helicobacter pylori infection. METHODS:From March 2005 till February 2010, we prospectively followed all patients with diffuse d...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/1471-230X-11-36

    authors: Khuroo MS,Khuroo NS,Khuroo MS

    更新日期:2011-04-11 00:00:00

  • A rapid, simple questionnaire to assess gastrointestinal symptoms after oral ferrous sulphate supplementation.

    abstract:BACKGROUND:Oral iron supplementation is often associated with rapid onset of gastrointestinal side-effects. The aim of this study was to develop and trial a short, simple questionnaire to capture these early side-effects and to determine which symptoms are more discriminating. METHODS:The study was a double-blind plac...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-230X-14-103

    authors: Pereira DI,Couto Irving SS,Lomer MC,Powell JJ

    更新日期:2014-06-04 00:00:00

  • TGF beta1 and PDGF AA override collagen type I inhibition of proliferation in human liver connective tissue cells.

    abstract:BACKGROUND:A marked expansion of the connective tissue population and an abnormal deposition of extracellular matrix proteins are hallmarks of chronic and acute injuries to liver tissue. Liver connective tissue cells, also called stellate cells, derived from fibrotic liver have been thoroughly characterized and corresp...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/1471-230X-4-30

    authors: Geremias AT,Carvalho MA,Borojevic R,Monteiro AN

    更新日期:2004-12-03 00:00:00

  • IFI16 is involved in HBV-associated acute-on-chronic liver failure inflammation.

    abstract:BACKGROUND:Hepatitis B virus (HBV) is a hepatotropic DNA virus, and its DNA may be a potent inflammatory molecule. Interferon-inducible protein 16 (IFI16), a newly discovered DNA sensor, plays an important role in the process of inflammation in viral infections. Our study sought to identify a correlation between IFI16 ...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/s12876-018-0791-1

    authors: Pang X,Li X,Mo Z,Huang J,Deng H,Lei Z,Zheng X,Feng Z,Xie D,Gao Z

    更新日期:2018-05-09 00:00:00

  • Gynecomastia during imatinib mesylate treatment for gastrointestinal stromal tumor: a rare adverse event.

    abstract:BACKGROUND:Imatinib mesylate has been the standard therapeutic treatment for chronic myeloid leukemia, advanced and metastatic gastrointestinal stromal tumor (GIST). It is well tolerated with mild adverse effects. Gynecomastia development during the course of treatment has been rarely reported. METHODS:Ninety-eight pa...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/1471-230X-11-116

    authors: Liu H,Liao G,Yan Z

    更新日期:2011-11-02 00:00:00

  • Survey of general practitioners' knowledge about Helicobacter pylori infection.

    abstract:BACKGROUND:Helicobacter pylori, occurring throughout the world and causing gastroduodenal diseases, is one of the most common chronic bacterial agents in humans. The purpose of this study was to measure the general practitioners' (GPs) knowledge and practices pertaining to H. pylori infection. METHODS:A cross-sectiona...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/1471-230X-5-4

    authors: Canbaz S,Sunter AT,Peksen Y,Leblebicioglu H

    更新日期:2005-01-26 00:00:00

  • Tracking the foreign body, a rare cause of hepatic abscess.

    abstract:BACKGROUND:Foreign body ingestion complicated by perforation of the digestive tract is a well-known occurrence. Contrary to this, perforation by fishbones has most often been described in South East Asian populations, and has the unusual characteristic of often being paucisymptomatic until secondary complications occur...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/1471-230X-14-167

    authors: Dangoisse C,Laterre PF

    更新日期:2014-09-27 00:00:00

  • Adenosine preconditioning attenuates hepatic reperfusion injury in the rat by preventing the down-regulation of endothelial nitric oxide synthase.

    abstract:BACKGROUND:Previous work has suggested that in the liver, adenosine preconditioning is mediated by nitric oxide. Whether the endothelial isoform of nitric oxide synthase plays a part in this mechanism has however not yet been investigated. METHODS:Wistar rats were used (6 in each group)--Groups: (1) sham, (2) ischemia...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/1471-230x-2-22

    authors: Serracino-Inglott F,Virlos IT,Habib NA,Williamson RC,Mathie RT

    更新日期:2002-09-20 00:00:00

  • Early stage signet ring cell carcinoma of the colon examined by magnifying endoscopy with narrow-band imaging: a case report.

    abstract:BACKGROUND:Signet ring cell carcinoma of the colon and rectum is rare, and most cases are detected at an advanced stage. We present a case of primary signet ring cell carcinoma detected at an early stage by magnifying endoscopy with narrow-band imaging (NBI) and crystal violet staining. CASE PRESENTATION:A 73-year-old...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/s12876-015-0317-z

    authors: Ohnita K,Isomoto H,Akashi T,Hashiguchi K,Matsushima K,Minami H,Akazawa Y,Yamaguchi N,Takeshima F,To K,Takeshita H,Yasui H,Abe K,Nakao K

    更新日期:2015-07-24 00:00:00

  • Transarterial chemoembolization plus sorafenib for the management of unresectable hepatocellular carcinoma: a systematic review and meta-analysis.

    abstract:BACKGROUND:Transarterial chemoembolization (TACE) is the recommended treatment for hepatocellular carcinoma (HCC) patients at Barcelona Clinic Liver Cancer (BCLC) B-stage, whereas sorafenib is an orally administered small molecule target drug for BCLC C-stage. This updated systemic review and meta-analysis focuses on i...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1186/s12876-018-0849-0

    authors: Li L,Zhao W,Wang M,Hu J,Wang E,Zhao Y,Liu L

    更新日期:2018-09-04 00:00:00

  • Role of vitamin D3 combined to alginates in preventing acid and oxidative injury in cultured gastric epithelial cells.

    abstract:BACKGROUND:Gastric diseases are a worldwide problem in modern society, as reported in the USA, in the range of 0.5-2 episodes/year/person and an incidence of 5-100 episodes/1000/week according to seasons and age. There is convincing evidence that oxidative stress is involved in the pathogenesis of acute gastric injury....

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/s12876-016-0543-z

    authors: Uberti F,Bardelli C,Morsanuto V,Ghirlanda S,Molinari C

    更新日期:2016-10-07 00:00:00

  • Haemodynamic effects of plasma-expansion with hyperoncotic albumin in cirrhotic patients with renal failure: a prospective interventional study.

    abstract:BACKGROUND:Patients with advanced cirrhosis of the liver typically display circulatory disturbance. Haemodynamic management may be critical for avoiding and treating functional renal failure in such patients. This study investigated the effects of plasma expansion with hyperoncotic albumin solution and the role of stat...

    journal_title:BMC gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.1186/1471-230X-8-39

    authors: Umgelter A,Wagner K,Reindl W,Nurtsch N,Huber W,Schmid RM

    更新日期:2008-08-27 00:00:00

  • Influence of cirrhosis on long-term prognosis after surgery in patients with combined hepatocellular-cholangiocarcinoma.

    abstract:BACKGROUND:Little is known about the prognostic impact of cirrhosis on long-term survival of patients with combined hepatocellular-cholangiocarcinoma (cHCC-CC) after hepatic resection. The aim of this study was to elucidate the long-term outcome of hepatectomy in cHCC-CC patients with cirrhosis. METHODS:A total of 144...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/s12876-017-0584-y

    authors: Zhou YM,Sui CJ,Zhang XF,Li B,Yang JM

    更新日期:2017-02-10 00:00:00

  • Gastric bacterial Flora in patients Harbouring Helicobacter pylori with or without chronic dyspepsia: analysis with matrix-assisted laser desorption ionization time-of-flight mass spectroscopy.

    abstract:BACKGROUND:The gastric microbiota has recently been implicated in the causation of organic/structural gastroduodenal diseases (gastric and duodenal ulcers, gastric cancer) in patients with Helicobacter pylori (H. pylori) infection. We aimed to ascertain, in patients harbouring H. pylori, the role of the gastric microbi...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/s12876-018-0744-8

    authors: Pereira V,Abraham P,Nallapeta S,Shetty A

    更新日期:2018-01-26 00:00:00

  • Comparison of oesophageal function tests between Chinese non-erosive reflux disease and reflux hypersensitivity patients.

    abstract:BACKGROUND:By means of 24 h multi-channel intraluminal impedance and pH recording (MII/pH), patients with heartburn and normal upper gastrointestinal endoscopy findings can be classified into those with non-erosive reflux disease (NERD) and those with reflux hypersensitivity (RH). Therefore, in this study, we investiga...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/s12876-017-0624-7

    authors: Gao F,Gao Y,Chen X,Qian J,Zhang J

    更新日期:2017-05-23 00:00:00

  • Acute cholestasis as uncommon onset of Kawasaki disease: a case report.

    abstract:BACKGROUND:Kawasaki disease (KD) or mucocutaneous lymph node syndrome is a vasculitis that mostly occurs in young children. Adult-onset KD (AKD) is rare and often misdiagnosed. Here we report a rare case of KD with cholestasis as principal symptom. CASE PRESENTATION:A 43-year-old caucasian man was admitted to our hosp...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/s12876-020-01495-6

    authors: Gallerani M,Pala M,Fabbian F,De Giorgi A

    更新日期:2020-10-28 00:00:00

  • Stenting as a bridge to surgery for extra-colonic malignancy induced colorectal obstruction: preliminary experience.

    abstract:BACKGROUND:The majority of colonic obstructions result from colorectal cancer. However, malignancies of extra-colonic origin can also disrupt colorectal patency, and the efficacy of self-expanding metal stents (SEMS) insertion as a bridge to surgery in these patients are still in debate. The aim of this study is to eva...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/s12876-020-01273-4

    authors: Kim EJ,Han SH,Kim KO,Chung JW,Park DK,Kwon KA,Kim JH

    更新日期:2020-04-19 00:00:00

  • A meta-analysis of the association between IL28B polymorphisms and infection susceptibility of hepatitis B virus in Asian population.

    abstract:BACKGROUND:Several association studies with small sample sizes of two SNPs in IL28BB (rs12979860 and rs8099917) showed inconsistent results, so in this study, we aim to evaluate the association between the two SNPs and infection susceptibility of Hepatitis B Virus (HBV) in Asian population, especially in Chinese popula...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章,meta分析

    doi:10.1186/s12876-015-0286-2

    authors: Chen J,Wang W,Li X,Xu J

    更新日期:2015-05-12 00:00:00

  • Protocol of a multicentric prospective cohort study for the VALIDation of the IBD-disk instrument for assessing disability in inflammatory bowel diseases: the VALIDate study.

    abstract:BACKGROUND:Inflammatory Bowel Diseases (IBD) affect psychological, family, social and professional dimensions of patients' life, leading to disability which is essential to quantify as part of Patient-Reported Outcomes (PROs) newly included in the targets to reach in IBD patients. Up to now, the IBD-Disability Index (I...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/s12876-020-01246-7

    authors: Le Berre C,Bourreille A,Flamant M,Bouguen G,Siproudhis L,Dewitte M,Dib N,Cesbron-Metivier E,Goronflot T,Hanf M,Gourraud PA,Kerdreux E,Poinas A,Trang-Poisson C

    更新日期:2020-04-16 00:00:00

  • Early effect of oral administration of omeprazole with mosapride as compared with those of omeprazole alone on the intragastric pH.

    abstract:BACKGROUND:The ideal medication for acid-related diseases should have a rapid onset of action to promote hemostasis and cause efficient resolution of symptoms. The aim of our study was to comparatively investigate the inhibitory effect on gastric acid secretion of a single oral administration of omeprazole plus mosapri...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-230X-12-25

    authors: Iida H,Inamori M,Fujii T,Sekino Y,Endo H,Hosono K,Nonaka T,Koide T,Takahashi H,Yoneda M,Goto A,Abe Y,Kobayashi N,Kirikoshi H,Kubota K,Saito S,Gotoh E,Maeda S,Nakajima A

    更新日期:2012-03-26 00:00:00

  • Risk of inflammatory bowel disease following a diagnosis of irritable bowel syndrome.

    abstract:BACKGROUND:Irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) symptoms often overlap. In some IBS cases there are subtle inflammatory changes similar to the immune-mediated pathophysiology of IBD, and the risk of both increases after infectious gastroenteritis (IGE). METHODS:To evaluate the effect of ...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/1471-230X-12-55

    authors: Porter CK,Cash BD,Pimentel M,Akinseye A,Riddle MS

    更新日期:2012-05-28 00:00:00

  • Liver disease and 30-day mortality after colorectal cancer surgery: a Danish population-based cohort study.

    abstract:BACKGROUND:Colorectal cancer (CRC) is common, with surgery as the main curative treatment. The prevalence of chronic liver disease has increased, but knowledge is limited on postoperative mortality in patients with liver disease who undergo CRC surgery. Hence, we examined 30-day mortality after CRC surgery in patients ...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/1471-230X-13-66

    authors: Montomoli J,Erichsen R,Christiansen CF,Ulrichsen SP,Pedersen L,Nilsson T,Sørensen HT

    更新日期:2013-04-15 00:00:00

  • Pancreatic hamartoma: a case report and literature review.

    abstract:BACKGROUND:Pancreatic hamartoma is an extremely rare benign disease of the pancreas. Only 30 cases have been reported to date. CASE PRESENTATION:A 68-year-old man presented with an asymptomatic solid and multi-cystic lesion in the uncus of the pancreas, incidentally detected on abdominal enhanced computed tomography. ...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1186/s12876-016-0419-2

    authors: Matsushita D,Kurahara H,Mataki Y,Maemura K,Higashi M,Iino S,Sakoda M,Shinchi H,Ueno S,Natsugoe S

    更新日期:2016-01-14 00:00:00

  • Longitudinal fluctuations in PD1 and PD-L1 expression in association with changes in anti-viral immune response in chronic hepatitis B.

    abstract:BACKGROUND:Controversy exists regarding the role of PD1 and its ligand PD-L1 in chronic hepatitis B infection. In some studies, persistent HBV infection has been attributed to high levels of PD-1 and PD-L1 expression on HBV-specific T-cells and antigen-presenting cells (APCs) respectively. Other studies revealed that t...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章

    doi:10.1186/1471-230X-12-109

    authors: Wenjin Z,Chuanhui P,Yunle W,Lateef SA,Shusen Z

    更新日期:2012-08-16 00:00:00

  • Efficacy and safety of infliximab induction therapy in Crohn's Disease in Central Europe--a Hungarian nationwide observational study.

    abstract:BACKGROUND:Infliximab (IFX) has proven to be an effective addition to the therapeutic arsenal for refractory, fistulizing, and steroid dependent Crohn's disease (CD), with efficacy in the induction and maintenance of clinical remission of CD. Our objective in this study is to report the nationwide, multicenter experien...

    journal_title:BMC gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.1186/1471-230X-9-66

    authors: Miheller P,Lakatos PL,Horváth G,Molnár T,Szamosi T,Czeglédi Z,Salamon A,Czimmer J,Rumi G,Palatka K,Papp M,Jakab Z,Szabó A,Gelley A,Lakatos L,Barta Z,Balázs C,Rácz I,Zeher M,Döbrönte Z,Altorjay I,Hunyady B,Simo

    更新日期:2009-09-10 00:00:00