Abstract:
BACKGROUND:Intussusception (IS) is a form of acute intestinal obstruction that occurs mainly in infants and is usually of unknown cause. An association between IS and the first licensed rotavirus vaccine, a reassortant-tetravalent, rhesus-based rotavirus vaccine (RRV-TV), led to the withdrawal of the vaccine. New rotavirus vaccines have now been developed and extensively studied for their potential association with IS. This study aimed to describe the epidemiology and to estimate the incidence of IS in Latin American infants prior to new vaccine introduction. METHODS:Children under 2 years of age representing potential IS cases were enrolled in 16 centers in 11 Latin American countries from January 2003 to May 2005. IS cases were classified as definite, probable, possible or suspected as stated on the Brighton Collaboration Working Group guidelines. RESULTS:From 517 potential cases identified, 476 (92%) cases were classified as definite, 21 probable, 10 possible and 10 suspected for intussusception. Among the 476 definite IS cases, the median age at presentation was 6.4 months with 89% of cases aged <1 year. The male to female ratio was 1.5:1. The incidence of definite IS per 100,000 subject-years ranged from 1.9 in Brazil to 62.4 in Argentina for children <2 years of age, and from 3.8 in Brazil to 105.3 in Argentina for children aged <1 year. Median hospital stay was 4 days with a high prevalence of surgery as the primary treatment (65%). Most cases (88%) made a complete recovery, but 13 (3%) died. No clear seasonal pattern of IS cases emerged. CONCLUSIONS:This study describes the epidemiology and estimates the incidence of IS in Latin American infants prior to the introduction of new rotavirus vaccines. The incidence of IS was found to vary between different countries, as observed in previous studies. TRIAL REGISTRATION:Clinical study identifier 999910/204 (SERO-EPI-IS-204).
journal_name
BMC Gastroenteroljournal_title
BMC gastroenterologyauthors
Sáez-Llorens X,Velázquez FR,Lopez P,Espinoza F,Linhares AC,Abate H,Nuñez E,Venegas G,Vergara R,Jimenez AL,Rivera M,Aranza C,Richardson V,Macias-Parra M,Palacios GR,Rivera L,Ortega-Barria E,Cervantes Y,Rüttimann R,Rudoi
10.1186/1471-230X-13-95subject
Has Abstractpub_date
2013-05-27 00:00:00pages
95issn
1471-230Xpii
1471-230X-13-95journal_volume
13pub_type
杂志文章abstract:BACKGROUND:In primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) fatigue is a major clinical problem. Abnormal amino acid (AA) patterns have been implicated in the development of fatigue in several non-hepatological conditions but for PBC and PSC no data are available. This study aimed to identify...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-5-11
更新日期:2005-03-24 00:00:00
abstract:BACKGROUND:Microcirculatory disturbance is an important factor in the pathogenesis of Inflammatory Bowel Disease (IBD) but there have been few studies in this field. Confocal Laser Endomicroscopy (CLE) has been used over the last 10 years and has made it possible to explore the changes in microcirculation of the coloni...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-019-1037-6
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Calprotectin is a stable neutrophil protein, which can be measured in faecal samples. The faecal level of calprotectin increases during disease activity in ulcerative colitis (UC). Nonetheless, the relevance of faecal calprotectin (FC) measurement during granulomonocytapheresis (GMA) for UC has not yet been ...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-018-0853-4
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Vedolizumab has become a standard treatment for the inflammatory bowel diseases ulcerative colitis (UC) and Crohn's disease (CD). However, there is an ongoing debate on the ideal individual treatment algorithms and means to predict treatment response are not routinely established. AIMS:We aimed to describe ...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-021-01604-z
更新日期:2021-01-22 00:00:00
abstract:BACKGROUND:Haemorrhoids are a common problem in daily practice. However, symptoms may also be caused by other abnormalities in the rectum or colon. Data on the presence of these abnormalities in patients with haemorrhoids is sparse. To examine the prevalence of abnormalities of the colon or rectum in patients with and ...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-10-74
更新日期:2010-07-07 00:00:00
abstract:BACKGROUND:Gastric diseases are a worldwide problem in modern society, as reported in the USA, in the range of 0.5-2 episodes/year/person and an incidence of 5-100 episodes/1000/week according to seasons and age. There is convincing evidence that oxidative stress is involved in the pathogenesis of acute gastric injury....
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-016-0543-z
更新日期:2016-10-07 00:00:00
abstract:BACKGROUND:Previous work has suggested that in the liver, adenosine preconditioning is mediated by nitric oxide. Whether the endothelial isoform of nitric oxide synthase plays a part in this mechanism has however not yet been investigated. METHODS:Wistar rats were used (6 in each group)--Groups: (1) sham, (2) ischemia...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230x-2-22
更新日期:2002-09-20 00:00:00
abstract:BACKGROUND:Sleep disturbances are increasingly recognized as a common problem for children and adolescents with chronic pain conditions, but little is known about the prevalence, type, and impact of sleep problems in pediatric functional gastrointestinal disorders (FGIDs). The objectives of the current study were two-f...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-12-142
更新日期:2012-10-15 00:00:00
abstract:BACKGROUND:Endothelial nitric oxide synthase (eNOS) has previously been detected in the glandular part of the human gastric mucosa. Furthermore, nitric oxide (NO) has been shown to influence gastric secretion in various animal models. The present study was conducted to investigate the influence of exogenously and endog...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-4-16
更新日期:2004-08-06 00:00:00
abstract:BACKGROUND:Although laparoscopic surgery has been available for a long time and laparoscopic cholecystectomy has been performed universally, it is still not clear whether open appendectomy (OA) or laparoscopic appendectomy (LA) is the most appropriate surgical approach to acute appendicitis. The purpose of this work is...
journal_title:BMC gastroenterology
pub_type: 杂志文章,meta分析,评审
doi:10.1186/1471-230X-10-129
更新日期:2010-11-03 00:00:00
abstract:BACKGROUND:Capillary patterns (CP) observed by magnifying Narrow Band Imaging (NBI) are useful for differentiating non-adenomatous from adenomatous colorectal polyps. However, there are few studies concerning the effectiveness of magnifying NBI for determining the depth of invasion in early colorectal neoplasms. We aim...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-10-33
更新日期:2010-03-27 00:00:00
abstract:BACKGROUND:The elderly population presents higher morbidity of H. pylori associated diseases in proximal stomach. The specific pathogenesis and mechanism have not been clearly addressed. The gastric environment for H. pylori colonization is dynamic with increasing age. The aim of present study is to investigate the cor...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-018-0883-y
更新日期:2018-10-29 00:00:00
abstract:BACKGROUND:Recent improvements in stone extraction implements and apparatus have lessened the complexity of the endoscopic bile duct stone treatment. However, despite confirmation of complete removal, cases of residual stones have been reported, which can result in recurrent biliary symptoms, cholangitis, and pancreati...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-020-01428-3
更新日期:2020-08-24 00:00:00
abstract:BACKGROUND:Haemolytic uraemic syndrome is a rarely seen in adults often leading to critical illness. This case highlights how difficult it can be to establish a diagnosis and treat when a patient presents with bloody diarrhoea. CASE PRESENTATION:A 17-year-old Iraqi man presented to the emergency department with abdomi...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-019-1071-4
更新日期:2019-08-28 00:00:00
abstract:BACKGROUND:Most of the previous studies regarding the effects of gel-forming fibres have considered the gastric emptying of liquid or solid meals after the addition of pectin or guar gum. The influence of locust bean gum, on gastric emptying of nutrient semisolid meals in humans has been less well studied, despite its ...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-3-12
更新日期:2003-06-06 00:00:00
abstract:BACKGROUND:Advances in intensive care support such as therapeutic hypothermia or new liver assist devices have been the mainstay of treatment attempting to bridge the gap from acute liver failure to liver transplantation, but the efficacy of the available devices in reducing mortality has been questioned. To address th...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-11-79
更新日期:2011-07-14 00:00:00
abstract:BACKGROUND:Treatment effectiveness of Helicobacter pylori varies regionally and is decreasing worldwide, principally as a result of antibiotic resistant bacterium. Tetracycline is generally included in second line H. pylori eradication regimens. In Brazil, a high level of tetracycline resistance (TetR) is mainly associ...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-12-49
更新日期:2012-05-17 00:00:00
abstract:BACKGROUND:Amebiasis is a rare condition in developed countries but epidemiologically growing. Clinical manifestation may range from asymptomatic to invasive disease, amoebic liver abscess being the most common manifestation. We report a peculiar case of left hepatic amoebic liver abscess in a patient without a well-kn...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-020-01440-7
更新日期:2020-09-11 00:00:00
abstract:BACKGROUND:By means of 24 h multi-channel intraluminal impedance and pH recording (MII/pH), patients with heartburn and normal upper gastrointestinal endoscopy findings can be classified into those with non-erosive reflux disease (NERD) and those with reflux hypersensitivity (RH). Therefore, in this study, we investiga...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-017-0624-7
更新日期:2017-05-23 00:00:00
abstract:BACKGROUND:Systemic sclerosis (SSc) is a generalized disorder of unknown etiology affecting the connective tissue of the body. It affects the skin and various internal organs. Gastrointestinal tract involvement is seen in almost 90% of the patients. Esophagus is the most frequently affected part of the gastrointestinal...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-015-0241-2
更新日期:2015-02-15 00:00:00
abstract:BACKGROUND:Faecal calprotectin (FC) is one of the most widely used non-invasive tests for the diagnosis and assessment of Crohn's disease (CD) activity. Despite this, factors other than disease activity which affect levels have not been extensively reviewed. This is of importance when using FC in the diagnostic setting...
journal_title:BMC gastroenterology
pub_type: 杂志文章,评审
doi:10.1186/s12876-016-0535-z
更新日期:2016-10-07 00:00:00
abstract:BACKGROUND:Coeliac disease is characterised by villous atrophy, which usually normalises after gluten withdrawal. Sometimes the revaluation of duodenal histology is required during follow-up, even if the methodology for comparing duodenal histology before and after introducing a gluten-free diet is not yet established....
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-015-0361-8
更新日期:2015-10-14 00:00:00
abstract:BACKGROUND:Rumination syndrome (RS) is a functional gastrointestinal disorder (FGD) increasingly recognized in children and adolescents. The epidemiology of this condition in school aged children is poorly understood. The main objective of this study was to assess the prevalence of rumination and other related associat...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-12-163
更新日期:2012-11-16 00:00:00
abstract:BACKGROUND:As anorexia and hypermetabolism are common in cirrhosis, leptin levels may be increased in this disease. In this study, we investigated the relation between the severity of disease and serum leptin levels in post-hepatitis cirrhosis and the role of body composition, gender and viral aetiology of cirrhosis in...
journal_title:BMC gastroenterology
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-230X-4-23
更新日期:2004-09-23 00:00:00
abstract:BACKGROUND:Hepatitis C virus (HCV) infection is commonly associated with a disturbance of glucose metabolism. However, there have been conflicting reports on whether the clearance of the HCV may be followed by changes of serum blood glucose and insulin resistance. The aim of the present study was to evaluate the impact...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-019-1003-3
更新日期:2019-06-13 00:00:00
abstract:BACKGROUND:Gastrointestinal fistula (GIF) in severe acute pancreatitis (SAP) is considered as a sparse episode and studied sporadically in the literature. There is paucity of data on the prediction of the effect on risk of GIF in patient with SAP. This study was aimed to investigate risk factors related to GIF in the d...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-017-0587-8
更新日期:2017-02-14 00:00:00
abstract:BACKGROUND:Acute pancreatitis (AP) is associated with considerable morbidity and mortality. Current severity scores include multiple variables and some of them are only complete within 48 h of admission. Red cell distribution width (RDW) is a simple and routine parameter that seems to be related to inflammatory status....
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-018-0834-7
更新日期:2018-07-05 00:00:00
abstract:BACKGROUND:Perforation of the colon occurring during or shortly following colonoscopy or barium enema is a rare complication of collagenous colitis (CC). "Spontaneous" perforation in CC, in which no instigating factor is identified, is even less common, with only five cases reported to date. We report herein an additio...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-016-0533-1
更新日期:2016-10-06 00:00:00
abstract:BACKGROUND:Pancreatic hamartoma is an extremely rare benign disease of the pancreas. Only 30 cases have been reported to date. CASE PRESENTATION:A 68-year-old man presented with an asymptomatic solid and multi-cystic lesion in the uncus of the pancreas, incidentally detected on abdominal enhanced computed tomography. ...
journal_title:BMC gastroenterology
pub_type: 杂志文章,评审
doi:10.1186/s12876-016-0419-2
更新日期:2016-01-14 00:00:00
abstract:BACKGROUND:The current clinical practice on chronic hepatitis B (CHB) requires better on-treatment monitoring of viral persistence. Quantified assays for hepatitis B surface antigen (HBsAg) and core-related antigen (HBcrAg) hold promise for further optimization of therapy. Here, we aimed to characterize HBcrAg during t...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-017-0703-9
更新日期:2017-12-04 00:00:00