A novel collagen area fraction index to quantitatively assess bowel fibrosis in patients with Crohn's disease.

abstract：BACKGROUND:Desmoid tumors are a group of benign, invasive, solid tumors that are relatively rare in the general population, but can occur in up to 21 % of patients with Familial Adenomatous Polyposis (FAP). They can be difficult to treat and have high rates of recurrence even after resection. Our goal with this study w...

journal_title：BMC gastroenterology

authors： Slowik V,Attard T,Dai H,Shah R,Septer S

更新日期：2015-07-16 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection is commonly associated with a disturbance of glucose metabolism. However, there have been conflicting reports on whether the clearance of the HCV may be followed by changes of serum blood glucose and insulin resistance. The aim of the present study was to evaluate the impact...

journal_title：BMC gastroenterology

authors： Li Y,Wang X,Yu G,Sun H,Lv J,Chi X,Wu R,Gao X,Niu J

更新日期：2019-06-13 00:00:00

abstract：BACKGROUND:Faecal calprotectin (FC) is one of the most widely used non-invasive tests for the diagnosis and assessment of Crohn's disease (CD) activity. Despite this, factors other than disease activity which affect levels have not been extensively reviewed. This is of importance when using FC in the diagnostic setting...

journal_title：BMC gastroenterology

authors： Mendall MA,Chan D,Patel R,Kumar D

更新日期：2016-10-07 00:00:00

abstract：BACKGROUND:Enhanced expression of MAdCAM-1 (mucosal addressin cell adhesion molecule-1) is associated with the onset and progression of inflammatory bowel disease. The clinical significance of elevated MAdCAM-1 expression is supported by studies showing that immunoneutralization of MAdCAM-1, or its ligands reduce infla...

journal_title：BMC gastroenterology

authors： Sasaki M,Jordan P,Houghton J,Meng X,Itoh M,Joh T,Alexander JS

更新日期：2003-02-20 00:00:00

abstract：BACKGROUND:Transient elastography (TE) is an innovative, noninvasive technique to assess liver fibrosis by measuring liver stiffness in patients with chronic liver diseases. The purpose of this study has been to explore the accuracy of TE and clinical parameters in predicting the presence of esophageal/gastric varices ...

journal_title：BMC gastroenterology

authors： Chongsrisawat V,Vejapipat P,Siripon N,Poovorawan Y

更新日期：2011-04-18 00:00:00

abstract：BACKGROUND:The prevalence of esophageal neoplasia in head and neck (H&N) cancer patients is not low; however, routine esophageal surveillance is not included in staging of newly-diagnosed H&N cancers. We aimed to investigate the risk factors for synchronous esophageal neoplasia and the impact of endoscopy on management...

journal_title：BMC gastroenterology

authors： Chung CS,Liao LJ,Lo WC,Chou YH,Chang YC,Lin YC,Hsu WF,Shueng PW,Lee TH

更新日期：2013-10-25 00:00:00

abstract：BACKGROUND:Microscopic colitis presents with similar symptoms to classic inflammatory bowel diseases. Osteoporosis is a common complication of Crohn's disease but there are no data concerning bone metabolism in microscopic colitis. AIMS:The aim of the present study was to evaluate bone density and metabolism in patien...

journal_title：BMC gastroenterology

authors： Lorinczy K,Lakatos G,Müllner K,Hritz I,Lakatos PL,Tulassay Z,Miheller P

更新日期：2011-05-19 00:00:00

abstract：BACKGROUND:Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare autosomal recessive disorder caused by mutations in TYMP gene, encoding nuclear thymidine phosphorylase (TP). MNGIE mainly presents with gastrointestinal symptoms and is mostly misdiagnosed in many patients as malabsorption syndrome, inf...

journal_title：BMC gastroenterology

authors： Habibzadeh P,Silawi M,Dastsooz H,Bahramjahan S,Ezzatzadegan Jahromi S,Ostovan VR,Yavarian M,Mofatteh M,Faghihi MA

更新日期：2020-05-08 00:00:00

abstract：BACKGROUND:Measurements of CFTR function in rectal biopsies ex vivo have been used for diagnosis and prognosis of Cystic Fibrosis (CF) disease. Here, we aimed to evaluate this procedure regarding: i) viability of the rectal specimens obtained by biopsy forceps for ex vivo bioelectrical and biochemical laboratory analys...

journal_title：BMC gastroenterology

authors： Servidoni MF,Sousa M,Vinagre AM,Cardoso SR,Ribeiro MA,Meirelles LR,de Carvalho RB,Kunzelmann K,Ribeiro AF,Ribeiro JD,Amaral MD

更新日期：2013-05-20 00:00:00

abstract：BACKGROUND:Cholelithiasis is the gallstone disease (GSD) where stones are formed in the gallbladder. The main function of the gallbladder is to concentrate bile by the absorption of water and sodium. GSD has high prevalence among elderly adults. There are three major types of gallstones found in patients, White, Black ...

journal_title：BMC gastroenterology

authors： Kleiner O,Ramesh J,Huleihel M,Cohen B,Kantarovich K,Levi C,Polyak B,Marks RS,Mordehai J,Cohen Z,Mordechai S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Hepatic expression of Sonic Hedgehog (SHH) is associated with Non-alcoholic fatty liver disease (NAFLD) and development of Non-alcoholic steatohepatitis (NASH). Hepatic SHH detection increases with the diagnosis of NASH. This pilot study was designed to confirm that staining for SHH is useful in NASH diagnos...

journal_title：BMC gastroenterology

authors： Estep M,Mehta R,Bratthauer G,Alaparthi L,Monge F,Ali S,Abdelatif D,Younoszai Z,Stepanova M,Goodman ZD,Younossi ZM

更新日期：2019-02-11 00:00:00

abstract：BACKGROUND:It is unknown whether narrow-band imaging (NBI) could be more effective than high-definition white-light endoscopy (HD-WLE) in detecting serrated lesions in patients with prior serrated lesions > 5 mm not completely fulfilling serrated polyposis syndrome (SPS) criteria. METHODS:We conducted a randomized, cr...

journal_title：BMC gastroenterology

authors： Riu Pons F,Andreu M,Naranjo D,Álvarez-González MA,Seoane A,Dedeu JM,Barranco L,Bessa X

更新日期：2020-04-16 00:00:00

abstract：BACKGROUND:Approximately 0.2-1 % of children suffers from abdominal migraine (AM). Pathophysiology of AM has not been adequately studied. This study evaluated gastric motility in children with AM. METHODS:Seventeen children (6 boys), within an age range of 4-15 years, referred to a tertiary care paediatric unit, North...

journal_title：BMC gastroenterology

authors： Devanarayana NM,Rajindrajith S,Benninga MA

更新日期：2016-02-29 00:00:00

abstract：BACKGROUND:Chronic active Epstein-Barr virus infection (CAEBV) is defined as Epstein-Barr virus (EBV)-positive T/NK cell-related neoplasia, and its major clinical symptom is systemic inflammation presenting as infectious mononucleocytosis, whereas enteritis and diarrhea are minor clinical symptoms. The complex mixture ...

journal_title：BMC gastroenterology

authors： Aihara Y,Moriya K,Shimozato N,Nagamatsu S,Kobayashi S,Uejima M,Matsuo H,Ishida E,Yagi H,Nakatani T,Yoshiji H,Kikuchi E

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:Recent evidence cautions against the use of non-selective beta-blockers (NSBB) in patients with refractory ascites or spontaneous bacterial peritonitis while other data suggests a survival benefit in patients with advanced liver disease. The aim of this study was to describe the use and impact of NSBB in pat...

journal_title：BMC gastroenterology

authors： Ngwa T,Orman E,Gomez EV,Vuppalanchi R,Kubal C,Chalasani N,Ghabril M

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:Oral anticoagulants like the coumarin derivatives are characterised by a particularly narrow therapeutic range. Any interfering co-medication can pose a challenge to establishing a stable anticoagulant dosage regimen and thus present a serious risk for the patient. Here we describe two cases of patients on a...

journal_title：BMC gastroenterology

authors： Enderle C,Müller W,Grass U

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:There is insufficient evidence on the effectiveness of acupuncture for irritable bowel syndrome (IBS) for conclusions to be drawn. Given the current interest in acupuncture by patients, it is in the public interest to establish more rigorous evidence. Building on the positive findings from a pilot study, in ...

journal_title：BMC gastroenterology

authors： MacPherson H,Bland M,Bloor K,Cox H,Geddes D,Kang'ombe A,Reynolds J,Stamuli E,Stuardi T,Tilbrook H,Torgerson D,Whorwell P

更新日期：2010-06-17 00:00:00

abstract：BACKGROUND:A tenth of patients with involuntary weight loss (IWL) have gastrointestinal cancer. Ferritin is the first parameter to be modified during the process leading to iron deficiency anaemia, therefore it should be the most sensitive. The aim of this study was to assess the ability of ferritin to rule out gastroi...

journal_title：BMC gastroenterology

authors： Baicus C,Caraiola S,Rimbas M,Patrascu R,Baicus A,GSSPI.

更新日期：2012-07-09 00:00:00

abstract：BACKGROUND:Endoscopic balloon dilation and/or plastic stent placement has been a standard method for treating biliary strictures complicated post living donor liver transplantation (LDLT). The strictures may be refractory to endoscopic treatment and require long-term stent placement. However, consensus on the optimal p...

journal_title：BMC gastroenterology

authors： Koizumi M,Kumagi T,Kuroda T,Imamura Y,Kanemitsu K,Ogawa K,Takada Y,Hiasa Y

更新日期：2020-04-06 00:00:00

abstract：BACKGROUND:Hereditary diffuse gastric cancer is a rare condition that accounts for approximately 1-3% of all gastric cancer cases. Due to its rapid and invasive growth pattern, it is associated with a very poor prognosis. As a result, comprehensive genetic testing is imperative in patients who meet the current testing ...

journal_title：BMC gastroenterology

authors： Niemeyer E,Mofid H,Zornig C,Burandt EC,Stein A,Block A,Volk AE

更新日期：2020-05-03 00:00:00

abstract：BACKGROUND:Saturated fatty acids are thought to be of relevance for the development of non-alcoholic fatty liver disease and obesity. However, the underlying mechanisms are poorly understood. In previous studies we found that food-derived carbohydrates such as fructose alter the intestinal serotonergic system while ind...

journal_title：BMC gastroenterology

authors： Ritze Y,Böhle M,Haub S,Hubert A,Enck P,Zipfel S,Bischoff SC

更新日期：2013-12-09 00:00:00

abstract：BACKGROUND:Pegylated interferon (PEG-IFN) alfa-2b is recommended for chronic hepatitis B (CHB). We aimed to investigate the sustainability of off-treatment responses among Chinese HBeAg-positive CHB patients treated with PEG-IFN alfa-2b from a randomized trial. METHODS:Eligible Chinese patients (n = 322) were followed...

journal_title：BMC gastroenterology

authors： Sun J,Ding H,Chen G,Wang G,Wei L,Zhang J,Xie Q,Wan M,Tang H,Chen S,Gao Z,Wang Y,Zhang D,Huang W,Sheng J,Ning Q,Yang D,Lu J,Pan C,Yang Y,Wang J,Sun C,Wang Q,Hou J

更新日期：2019-05-02 00:00:00

abstract：BACKGROUND:Coeliac disease is characterised by villous atrophy, which usually normalises after gluten withdrawal. Sometimes the revaluation of duodenal histology is required during follow-up, even if the methodology for comparing duodenal histology before and after introducing a gluten-free diet is not yet established....

journal_title：BMC gastroenterology

authors： Elli L,Zini E,Tomba C,Bardella MT,Bosari S,Conte D,Runza L,Roncoroni L,Ferrero S

更新日期：2015-10-14 00:00:00

abstract：BACKGROUND:We aimed to provide empirical evidence of how spectrum effects can affect the sensitivity of histological assessment of Helicobacter pylori infection, which may contribute to explain the heterogeneity in prevalence estimates across populations with expectedly similar prevalence. METHODS:Cross-sectional eval...

journal_title：BMC gastroenterology

authors： Lunet N,Peleteiro B,Carrilho C,Figueiredo C,Azevedo A

更新日期：2009-12-24 00:00:00

abstract：BACKGROUND:Enteric glia cells (EGC) play an important role in the maintenance of intestinal mucosa integrity. During the course of acute Crohn's disease (CD), mucosal EGC progressively undergo apoptosis, though the mechanisms are largely unknown. We investigated the role of Glial-derived neurotrophic factor (GDNF) in t...

journal_title：BMC gastroenterology

authors： Steinkamp M,Gundel H,Schulte N,Spaniol U,Pflueger C,Zizer E,von Boyen GB

更新日期：2012-01-17 00:00:00

abstract：BACKGROUND:FibroTest (FT) is a validated biomarker of fibrosis. To assess the applicability rate and to reduce the risk of false positives/negatives (RFPN), security algorithms were developed. The aims were to estimate the prevalence of RFPN and of proven failures, and to identify factors associated with their occurren...

journal_title：BMC gastroenterology

authors： Poynard T,Munteanu M,Deckmyn O,Ngo Y,Drane F,Messous D,Castille JM,Housset C,Ratziu V,Imbert-Bismut F

更新日期：2011-04-14 00:00:00

abstract：BACKGROUND:HCC predominantly develops in the condition of chronic inflammation that has led to liver cirrhosis. A small proportion of patients with HCC is diagnosed in the non-cirrhotic liver (NCL). Data on patients with HCC in NCL in advanced stages are scarce. METHODS:A retrospective analysis was performed comparing...

journal_title：BMC gastroenterology

authors： Schütte K,Schulz C,Poranzke J,Antweiler K,Bornschein J,Bretschneider T,Arend J,Ricke J,Malfertheiner P

更新日期：2014-07-03 00:00:00

abstract：BACKGROUND:The emergence of multidrug-resistant (MDR) Escherichia coli (E. coli), particularly E. coli sequence type ST131, is becoming a global concern. Commensal bacteria, an important reservoir of antibiotic resistance genes, facilitate the spread of such genes to pathogenic bacterial strains. The objective of the s...

journal_title：BMC gastroenterology

authors： Huang IF,Lee WY,Wang JL,Hung CH,Hu HH,Hung WY,Hung YJ,Chen WC,Shen YT,Cheng MF

更新日期：2018-06-15 00:00:00

abstract：BACKGROUND:Chronic diarrhea in adults is a common symptom with a wide range of underlying etiologies. Although various strategies have been proposed for evaluation, there are still cases with undetermined origins even after extensive workup. Amyloidosis with gastrointestinal (GI) involvement is one of the causes that s...

journal_title：BMC gastroenterology

authors： Wang C,Li Y,Jin Y,Zhou W,Zhu Y,Yao F,Qian J

更新日期：2013-04-24 00:00:00

abstract：BACKGROUND:The clinical course of chronic pancreatitis is still unpredictable, which relates to the lack of the availability of a clinical classification. Therefore, patient populations cannot be compared, the course and the outcome of the disease remain undetermined in the individual patient, and treatment is not stan...

journal_title：BMC gastroenterology

authors： Büchler MW,Martignoni ME,Friess H,Malfertheiner P

更新日期：2009-12-14 00:00:00