Clinical and molecular characterization of a patient with mitochondrial Neurogastrointestinal Encephalomyopathy.

abstract：BACKGROUND:Gastric diseases are a worldwide problem in modern society, as reported in the USA, in the range of 0.5-2 episodes/year/person and an incidence of 5-100 episodes/1000/week according to seasons and age. There is convincing evidence that oxidative stress is involved in the pathogenesis of acute gastric injury....

journal_title：BMC gastroenterology

authors： Uberti F,Bardelli C,Morsanuto V,Ghirlanda S,Molinari C

更新日期：2016-10-07 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is common, with surgery as the main curative treatment. The prevalence of chronic liver disease has increased, but knowledge is limited on postoperative mortality in patients with liver disease who undergo CRC surgery. Hence, we examined 30-day mortality after CRC surgery in patients ...

journal_title：BMC gastroenterology

authors： Montomoli J,Erichsen R,Christiansen CF,Ulrichsen SP,Pedersen L,Nilsson T,Sørensen HT

更新日期：2013-04-15 00:00:00

abstract：BACKGROUND:Microscopic colitis presents with similar symptoms to classic inflammatory bowel diseases. Osteoporosis is a common complication of Crohn's disease but there are no data concerning bone metabolism in microscopic colitis. AIMS:The aim of the present study was to evaluate bone density and metabolism in patien...

journal_title：BMC gastroenterology

authors： Lorinczy K,Lakatos G,Müllner K,Hritz I,Lakatos PL,Tulassay Z,Miheller P

更新日期：2011-05-19 00:00:00

abstract：BACKGROUND:The aim of this study was to develop and psychometrically test a short, patient-reported questionnaire to be used in clinical practice for patients with Irritable Bowel Syndrome (IBS). The Visual Analogue Scale for Irritable Bowel Syndrome (VAS-IBS) questionnaire was designed to measure the treatment respons...

journal_title：BMC gastroenterology

authors： Bengtsson M,Ohlsson B,Ulander K

更新日期：2007-05-03 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome (IBS) is defined as a multifactorial disorder associated with visceral hypersensitivity, altered gut motility and dysfunction of the brain-gut axis. Gut microbiota and its metabolites are proposed as possible etiological factors of IBS. Short chain fatty acids (SCFAs) induce both inh...

journal_title：BMC gastroenterology

authors： Shaidullov IF,Sorokina DM,Sitdikov FG,Hermann A,Abdulkhakov SR,Sitdikova GF

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND:Low 25-Hydroxy-vitamin-D; "25(OH)-D3" serum and vitamin D receptor (VDR) levels were recently correlated to advanced fibrosis. However, VDR mechanism in liver fibrosis modulations is not well understood. In this study, we aimed to evaluate changes in liver NK cells cytotoxicity due to modulations in VDR in C...

journal_title：BMC gastroenterology

authors： Salhab A,Amer J,Yinying L,Safadi R

更新日期：2020-04-10 00:00:00

abstract：BACKGROUND:Acute pancreatitis (AP) is associated with considerable morbidity and mortality. Current severity scores include multiple variables and some of them are only complete within 48 h of admission. Red cell distribution width (RDW) is a simple and routine parameter that seems to be related to inflammatory status....

journal_title：BMC gastroenterology

authors： Gravito-Soares M,Gravito-Soares E,Gomes D,Almeida N,Tomé L

更新日期：2018-07-05 00:00:00

abstract：BACKGROUND:The elderly population presents higher morbidity of H. pylori associated diseases in proximal stomach. The specific pathogenesis and mechanism have not been clearly addressed. The gastric environment for H. pylori colonization is dynamic with increasing age. The aim of present study is to investigate the cor...

journal_title：BMC gastroenterology

authors： Shi H,Xiong H,Qian W,Lin R

更新日期：2018-10-29 00:00:00

abstract：BACKGROUND:Benign biliary strictures may be a consequence of surgical procedures, chronic pancreatitis or iatrogenic injuries to the ampulla. Stents are increasingly being used for this indication, however it is not completely clear which stent type should be preferred. METHODS:A systematic review on stent placement f...

journal_title：BMC gastroenterology

authors： van Boeckel PG,Vleggaar FP,Siersema PD

更新日期：2009-12-17 00:00:00

abstract：BACKGROUND:Transarterial chemoembolization (TACE) and sorafenib are the therapeutic standard for intermediate and advanced stage hepatocellular carcinoma (HCC) patients respectively. High costs with adverse events (AE) of sorafenib might limit sorafenib dosage, further affecting therapeutic response. To attain greatest...

journal_title：BMC gastroenterology

authors： Hsiao WD,Peng CY,Chuang PH,Lai HC,Cheng KS,Chou JW,Chen YY,Yu CJ,Feng CL,Su WP,Chen SH,Kao JT

更新日期：2016-04-27 00:00:00

abstract：BACKGROUND:Although laparoscopic surgery has been available for a long time and laparoscopic cholecystectomy has been performed universally, it is still not clear whether open appendectomy (OA) or laparoscopic appendectomy (LA) is the most appropriate surgical approach to acute appendicitis. The purpose of this work is...

journal_title：BMC gastroenterology

authors： Li X,Zhang J,Sang L,Zhang W,Chu Z,Li X,Liu Y

更新日期：2010-11-03 00:00:00

abstract：BACKGROUND:The association between proinflammatory cytokine gene polymorphisms and gastric diseases related to Helicobacter pylori varies by population and geographic area.Our objective was to determine if the IL-1B -511 T>C and -31 C>T polymorphisms and H. pylori vacA genotypes are associated with risk of chronic gast...

journal_title：BMC gastroenterology

authors： Martínez-Carrillo DN,Garza-González E,Betancourt-Linares R,Mónico-Manzano T,Antúnez-Rivera C,Román-Román A,Flores-Alfaro E,Illades-Aguiar B,Fernández-Tilapa G

更新日期：2010-10-27 00:00:00

abstract：BACKGROUND:High dose intravenous proton pump inhibitor after endoscopic therapy for peptic ulcer bleeding has been recommended as adjuvant therapy. Whether oral proton pump inhibitor can replace intravenous proton pump inhibitor in this setting is unknown. This study aims to compare the clinical efficacy of oral and in...

journal_title：BMC gastroenterology

authors： Yen HH,Yang CW,Su WW,Soon MS,Wu SS,Lin HJ

更新日期：2012-06-08 00:00:00

abstract：BACKGROUND:A variety of extra-intestinal manifestations (EIMs), including hepatobiliary complications, are associated with inflammatory bowel disease (IBD). Mesenchymal stem cells (MSCs) have been shown to play a potential role in the therapy of IBD. This study was designed to investigate the effect and mechanism of MS...

journal_title：BMC gastroenterology

authors： Niu GC,Liu L,Zheng L,Zhang H,Shih DQ,Zhang X

更新日期：2018-08-13 00:00:00

abstract：BACKGROUND:The nuclear protein high-mobility group box 1 (HMGB1) is a key trigger for the inflammatory reaction during liver ischemia reperfusion injury (IRI). Hydrogen treatment was recently associated with down-regulation of the expression of HMGB1 and pro-inflammatory cytokines during sepsis and myocardial IRI, but ...

journal_title：BMC gastroenterology

authors： Liu Y,Yang L,Tao K,Vizcaychipi MP,Lloyd DM,Sun X,Irwin MG,Ma D,Yu W

更新日期：2014-01-12 00:00:00

abstract：BACKGROUND:Real-time tissue sonoelastography (EG) is a new non-invasive technique that visualizes differences in tissue strain. We evaluated the usefulness of EG in patients with ulcerative colitis (UC) by investigating the association between EG and colonoscopic findings and disease activity. METHODS:Thirty-seven UC ...

journal_title：BMC gastroenterology

authors： Ishikawa D,Ando T,Watanabe O,Ishiguro K,Maeda O,Miyake N,Nakamura M,Miyahara R,Ohmiya N,Hirooka Y,El-Omar EM,Goto H

更新日期：2011-03-31 00:00:00

abstract：BACKGROUND AND AIM:Carbohydrate deficient transferrin (CDT) is the most specific serum biomarker of heavy alcohol consumption, defined as ≥ 350-420 g alcohol/week. Despite introduction of a standardized reference measurement technique, widespread use of CDT remains limited due to low sensitivity. The aim of this study ...

journal_title：BMC gastroenterology

authors： Fagan KJ,Irvine KM,McWhinney BC,Fletcher LM,Horsfall LU,Johnson L,O'Rourke P,Martin J,Scott I,Pretorius CJ,Ungerer JP,Powell EE

更新日期：2014-05-22 00:00:00

abstract：BACKGROUND:There is consistent evidence that 50% of patients with acute, steroid-resistant flare of ulcerative colitis (UC) may achieve remission and avoid colectomy if treated with cyclosporin (CsA). However, follow-up of the responders has shown that most of them relapse and need surgery shortly after the response. W...

journal_title：BMC gastroenterology

authors： Actis GC,Fadda M,David E,Sapino A

更新日期：2007-03-27 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is mutually and bidirectionally linked with metabolic syndrome (MetS) of which it is both the cause and the consequences. Worldwide, 6.3 to 33% of the general populations are estimated to suffer from the disease with even higher prevalence in the group sharing metabo...

journal_title：BMC gastroenterology

authors： Pardhe BD,Shakya S,Bhetwal A,Mathias J,Khanal PR,Pandit R,Shakya J,Joshi HO,Marahatta SB

更新日期：2018-07-06 00:00:00

abstract：BACKGROUND:Treatment effectiveness of Helicobacter pylori varies regionally and is decreasing worldwide, principally as a result of antibiotic resistant bacterium. Tetracycline is generally included in second line H. pylori eradication regimens. In Brazil, a high level of tetracycline resistance (TetR) is mainly associ...

journal_title：BMC gastroenterology

authors： Suzuki RB,Almeida CM,Sperança MA

更新日期：2012-05-17 00:00:00

abstract：BACKGROUND:Familial adenomatous polyposis (FAP) is a rare, autosomal dominant disease clinically characterized by the early onset of many adenomatous polyps throughout the colon, which turn into colon cancer, if left untreated. In FAP patients, polyps can also occur in the upper gastrointestinal (GI) tract, especially ...

journal_title：BMC gastroenterology

authors： Purchiaroni F,Nakajima T,Sakamoto T,Abe S,Saito Y

更新日期：2017-12-08 00:00:00

abstract：BACKGROUND:This study investigated a possible role of Escherichia coli in propagation and perpetuation of the chronic inflammation in ulcerative colitis (UC). The lesions of UC are located superficially on the rectal and/or colonic mucosa. It is suggested that the commensal bacteria of the digestive tract may play a ro...

journal_title：BMC gastroenterology

authors： Pilarczyk-Zurek M,Chmielarczyk A,Gosiewski T,Tomusiak A,Adamski P,Zwolinska-Wcislo M,Mach T,Heczko PB,Strus M

更新日期：2013-04-08 00:00:00

abstract：BACKGROUND:Pancreas divisum, the most common congenital anomaly of the pancreas, is caused by failure of the fusion of the ventral and dorsal pancreatic duct systems during embryological development. Although various pancreatic tumors can occur in patients with pancreas divisum, intraductal papillary mucinous neoplasm ...

journal_title：BMC gastroenterology

authors： Nishi T,Kawabata Y,Ishikawa N,Araki A,Yano S,Maruyama R,Tajima Y

更新日期：2015-07-08 00:00:00

abstract：BACKGROUND:Alpha-fetoprotein (AFP)-producing pancreatic neuroendocrine tumors (pNETs) are rare, and the few reported cases usually coexisted with other malignant components such as adenocarcinoma or hepatoid carcinoma. We present here the first case of pure AFP-producing pNET. CASE PRESENTATION:A 56-year-old male pati...

journal_title：BMC gastroenterology

authors： Zhu X,Yong H,Zhang L,Huang Y,Zheng J,Liu C,Xiu D,Zhang P

更新日期：2015-02-12 00:00:00

abstract：BACKGROUND:Gallstone disease (GSD) is a common gastrointestinal disorder throughout the world. The authors explored the incidence of GSD in Taiwan and its condition-associated predictive factors. METHODS:The initial study cohort comprised 2386 healthy adult participants, who were voluntarily admitted to a teaching hos...

journal_title：BMC gastroenterology

authors： Chen JY,Hsu CT,Liu JH,Tung TH

更新日期：2014-04-28 00:00:00

abstract：BACKGROUND:Foreign body ingestion complicated by perforation of the digestive tract is a well-known occurrence. Contrary to this, perforation by fishbones has most often been described in South East Asian populations, and has the unusual characteristic of often being paucisymptomatic until secondary complications occur...

journal_title：BMC gastroenterology

authors： Dangoisse C,Laterre PF

更新日期：2014-09-27 00:00:00

abstract：BACKGROUND:Symptoms suggestive of functional dyspepsia (FD) and irritable bowel syndrome (IBS) frequently overlap with those of gastroesophageal reflux disease. Despite the high prevalence of symptomatic overlap, the underlying etiology remains poorly defined. We assessed the correlation of symptomatic relief and healt...

journal_title：BMC gastroenterology

authors： Mönnikes H,Schwan T,van Rensburg C,Straszak A,Theek C,Lühmann R,Sander P,Tholen A

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Only a paucity of large-scale perspective and cross-sectional studies on H. pylori infection in China have been published. The purpose of this study was to investigate the prevalence and risk factors for H. pylori infection among residents of Jidong community located in Hebei Province of China. METHODS:A pe...

journal_title：BMC gastroenterology

authors： Wang W,Jiang W,Zhu S,Sun X,Li P,Liu K,Liu H,Gu J,Zhang S

更新日期：2019-11-14 00:00:00

abstract：BACKGROUND:We examined the intrinsic hepatic innervation after partial hepatectomy (PH) in rats and the presence and pattern of neural sprouting in regenerating liver. METHODS:Male Wistar rats (age 9-13 weeks-w, weight 204-356 g), were submitted to two-thirds PH. Rats were sacrificed at postoperative days (d) 1, 3, 5,...

journal_title：BMC gastroenterology

authors： Kandilis AN,Koskinas J,Vlachos I,Skaltsas S,Karandrea D,Karakitsos P,Pantopoulou A,Palaiologou M,Nikiteas N,Tiniakos DG,Perrea DN

更新日期：2014-11-25 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is the most common cancer in Europe with a mortality rate of almost 50%. The prognosis of patients is largely determined by the clinical and pathological stage at the time of diagnosis. Population screening has been shown to reduce CRC-related mortality rate. Most screening programs w...

journal_title：BMC gastroenterology

authors： Stegeman I,de Wijkerslooth TR,Mallant-Hent RC,de Groot K,Stroobants AK,Fockens P,Mundt M,Bossuyt PM,Dekker E

更新日期：2012-06-19 00:00:00