Lipid accumulation product (LAP) was independently associatedwith obstructive sleep apnea in patients with type 2 diabetes mellitus.

abstract：BACKGROUND:Hyperglycemia induces chromatin remodeling with consequences on differential gene expression in mouse hepatocytes, similar to what occurs during aging. The liver is the central organ for the regulation of glucose homeostasis and xenobiotic and lipid metabolism and is affected by insulin signaling. The precis...

journal_title：BMC endocrine disorders

authors： Ghiraldini FG,Silveira AB,Kleinjan DA,Gilbert N,Mello ML

更新日期：2014-03-03 00:00:00

abstract：BACKGROUND:Insulin resistance and diabetes are associated with increased oxidative stress and impairment of cellular defence systems. Our purpose was to investigate the interaction between glucose metabolism, antioxidative capacity and heat shock protein (HSP) defence in different skeletal muscle phenotypes among middl...

journal_title：BMC endocrine disorders

authors： Venojärvi M,Aunola S,Puhke R,Marniemi J,Hämäläinen H,Halonen JP,Lindström J,Rastas M,Hällsten K,Nuutila P,Hänninen O,Atalay M

更新日期：2008-03-27 00:00:00

abstract：BACKGROUND:Thyrotoxicosis is often caused by destructive thyroiditis (DT) or Graves' disease (GD), and a prompt and accurate differential diagnosis for thyrotoxicosis is needed as management strategy differs. A meta-analysis of published literature was performed to evaluate the diagnostic accuracy for differentiating G...

journal_title：BMC endocrine disorders

authors： Peng X,Wu S,Bie C,Tang H,Xiong Z,Tang S

更新日期：2019-06-06 00:00:00

abstract：:BACKGROUND: Fractionated plasma metanephrine measurements are commonly used in biochemical testing in search of pheochromocytoma. METHODS: We aimed to critically appraise the diagnostic efficacy of fractionated plasma free metanephrine measurements in detecting pheochromocytoma. Nine electronic databases, meeting abst...

journal_title：BMC endocrine disorders

authors： Sawka AM,Prebtani AP,Thabane L,Gafni A,Levine M,Young WF Jr

更新日期：2004-06-29 00:00:00

abstract：BACKGROUND:Diabetes mellitus is usually preceded by a pre-diabetic stage before the clinical presentation of the disease, the influence of which on persons' quality of life is not adequately elucidated. The purpose of this study was to compare the Health-Related Quality of Life (HRQOL) of persons with pre-diabetes with...

journal_title：BMC endocrine disorders

authors： Makrilakis K,Liatis S,Tsiakou A,Stathi C,Papachristoforou E,Perrea D,Katsilambros N,Kontodimopoulos N,Niakas D

更新日期：2018-05-29 00:00:00

abstract：BACKGROUND:The pathophysiology of type2 diabetes involves both insulin resistance and poor beta cell function. Studies have been done in several populations to assess the relative importance of these mechanisms in individual patients. In our environment studies to assess beta cell function have been done with glucagon ...

journal_title：BMC endocrine disorders

authors： Young EE,Chinenye S,Unachukwu CN

更新日期：2012-06-27 00:00:00

abstract：BACKGROUND:The objective was to examine how the indigenous naming, indigenous self-diagnosis and management of diabetes evolved with awareness in order to develop a socially oriented theoretical model for its care. METHODS:The data was collected through a one-year extended participant observation in Bafut, a rural hea...

journal_title：BMC endocrine disorders

authors： Awah PK,Unwin NC,Phillimore PR

更新日期：2009-02-19 00:00:00

abstract：BACKGROUND:Iodine deficiency affects nearly 1.9 billion people worldwide, but it can be prevented by salt iodization. This cross-sectional survey assessed current iodine status, iodized salt coverage and risk factors for goitre among schoolchildren in South Tajikistan. METHODS:Ten primary schools in four districts in ...

journal_title：BMC endocrine disorders

authors： Matthys B,Davlatmamadova M,Karimova G,Jean-Richard V,Zimmermann MB,Wyss K

更新日期：2013-11-02 00:00:00

abstract：BACKGROUND:The burden of non-communicable diseases is growing rapidly in low- and middle-income countries. Research suggests that health interventions that aim to improve patient self-management and empower patients to care actively for their disease will improve health outcomes over the long-term. There is, however, a...

journal_title：BMC endocrine disorders

authors： Abrahams N,Gilson L,Levitt NS,Dave JA

更新日期：2019-12-05 00:00:00

abstract：BACKGROUND:The aim of the present study of the general population was to identify the best predictor of metabolic risk among the body index variables evaluated with dual-energy X-ray absorptiometry (DEXA) or anthropometric indices including the waist to height ratio (WHtR). PATIENTS AND METHODS:Data from the Korean Na...

journal_title：BMC endocrine disorders

authors： Kang SH,Cho KH,Park JW,Do JY

更新日期：2015-12-08 00:00:00

abstract：BACKGROUND:Insufficient vitamin D status and increased renin-angiotensin system (RAS) activity have been associated with renal-vascular disease and nephropathy in diabetes. Accumulating evidence indicates that vitamin D receptor (VDR) activation lowers unfavorable RAS activity; however, more human intervention studies ...

journal_title：BMC endocrine disorders

authors： Brown JM,Secinaro K,Williams JS,Vaidya A

更新日期：2013-08-23 00:00:00

abstract：BACKGROUND:Medullary thyroid carcinoma is a malignant uncommon and aggressive tumour of the parafollicular C cells. In about 75% of cases it is sporadic while, in case of RET mutation, it is associated to multiple endocrine neoplasia type 2 (25% of cases). The biochemical features of medullary thyroid carcinoma include...

journal_title：BMC endocrine disorders

authors： Gambardella C,Offi C,Clarizia G,Romano RM,Cozzolino I,Montella M,Di Crescenzo RM,Mascolo M,Cangiano A,Di Martino S,Candela G,Docimo G

更新日期：2019-10-16 00:00:00

abstract：BACKGROUND:There are multiple criteria to define remission of type 2 diabetes (DM2) after bariatric surgery but there is not a specific one widely accepted. Our objectives were to compare diagnostic criteria for DM2 remission after bariatric surgery: Criteria from Spanish scientific associations (SEEN/SEEDO/SED) and fr...

journal_title：BMC endocrine disorders

authors： Alhambra-Expósito MR,Molina-Puerta MJ,Prior-Sánchez MI,Manzano-García G,Calañas-Continente A,Gálvez-Moreno MA

更新日期：2017-08-15 00:00:00

abstract：BACKGROUND:The hypertension cure rate of unilateral adrenalectomy in primary aldosteronism (PA) patients varies widely in existing studies. METHODS:We conducted an observational meta-analysis to summarize the pooled hypertension cure rate of unilateral adrenalectomy in PA patients. Comprehensive electronic searches of...

journal_title：BMC endocrine disorders

authors： Zhou Y,Zhang M,Ke S,Liu L

更新日期：2017-10-03 00:00:00

abstract：: Pituitary adenomas are associated with a variety of clinical manifestations resulting from excessive hormone secretion and tumor mass effects, and require a multidisciplinary management approach. This article discusses the treatment modalities for the management of patients with a prolactinoma, Cushing's disease and ...

journal_title：BMC endocrine disorders

authors： Biller BM,Colao A,Petersenn S,Bonert VS,Boscaro M

更新日期：2010-05-17 00:00:00

abstract：:Hypopituitarism is deficiency of one or more pituitary hormones, of which adrenocorticotrophic hormone (ACTH) deficiency is the most serious and potentially life-threatening. It may occur in isolation or, more commonly as part of more widespread pituitary failure. Diagnosis requires demonstration of subnormal cortisol...

journal_title：BMC endocrine disorders

authors： Garrahy A,Agha A

更新日期：2016-06-17 00:00:00

abstract：BACKGROUND:We investigated the association between sleep symptoms, which cause sleep disorder, and quality of life (QoL) among people with type 2 diabetes (T2D). METHODS:In this cross-sectional study of 342 people with T2D, the Japan National Health and Wellness Survey (NHWS) database 2016 were used. We treated the re...

journal_title：BMC endocrine disorders

authors： Hashimoto Y,Sakai R,Ikeda K,Fukui M

更新日期：2020-06-30 00:00:00

abstract：BACKGROUND:The detection of microvascular damage in type 1 diabetes is difficult and traditional investigations do not detect changes until they are well established. The purpose of this study was to investigate the combined ability of nailfold capillaroscopy, laser Doppler flowmetry, retinal vessel analysis and 24-hr ...

journal_title：BMC endocrine disorders

authors： Hosking SP,Bhatia R,Crock PA,Wright I,Squance ML,Reeves G

更新日期：2013-10-05 00:00:00

abstract：BACKGROUND:A growing body of evidence supports neutrophils as having an active role in the development of diabetic kidney disease (DKD). However, the clinical relevance of neutrophils and DKD in autoimmune diabetes remains unknown. This study aimed to investigate the relationship between circulating neutrophils and DKD...

journal_title：BMC endocrine disorders

authors： Yu Y,Lin Q,Ye D,Wang Y,He B,Li Y,Huang G,Zhou Z,Xiao Y

更新日期：2020-10-22 00:00:00

abstract：BACKGROUND:Telomeres are DNA repeat sequences necessary for DNA replication which shorten at cell division at a rate directly related to levels of oxidative stress. Critical telomere shortening predisposes to cell senescence and to epithelial malignancies. Type 2 diabetes is characterised by increased oxidative DNA dam...

journal_title：BMC endocrine disorders

authors： Kejariwal D,Stepien KM,Smith T,Kennedy H,Hughes DA,Sampson MJ

更新日期：2008-10-10 00:00:00

abstract：BACKGROUND:Sympathetic activity and insulin resistance have recently been linked with chronic tendon and musculoskeletal pain. Polycystic ovarian syndrome is linked with insulin resistance and increased sympathetic drive and was therefore an appropriate condition to study the effects of modulating sympathetic activity ...

journal_title：BMC endocrine disorders

authors： Jewson J,Lambert E,Sari C,Jona E,Shorakae S,Lambert G,Gaida J

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:Feel4Diabetes was a school and community based intervention aiming to promote healthy lifestyle and tackle obesity for the prevention of type 2 diabetes among families in 6 European countries. We conducted this literature review in order to guide the development of evidence-based implementation of the Feel4D...

journal_title：BMC endocrine disorders

authors： Kivelä J,Wikström K,Virtanen E,Georgoulis M,Cardon G,Civeira F,Iotova V,Karuranga E,Ko W,Liatis S,Makrilakis K,Manios Y,Mateo-Gallego R,Nanasi A,Rurik I,Tankova T,Tsochev K,Van Stappen V,Lindström J,Feel4Diabetes re

更新日期：2020-03-12 00:00:00

abstract：BACKGROUND:Type 2 diabetic patients display significantly higher incidence of cardiovascular (CV) events including stroke compared to non-diabetics. Morning blood pressure surge (MBPS) and blunted systolic night-day (SND) ratio have been associated with CV events in hypertensive patients. No studies have evaluated MBPS...

journal_title：BMC endocrine disorders

authors： Lyhne JM,Laugesen E,Høyem P,Cichosz S,Christiansen JS,Knudsen ST,Hansen KW,Hansen TK,Poulsen PL

更新日期：2015-12-03 00:00:00

abstract：BACKGROUND:Most studies on cortisol have focused on smaller, selected samples. We therefore aimed to sex-specifically study the diurnal cortisol pattern and explore its association with abdominal obesity in a large unselected population. METHODS:In 2001-2004, 1811 men and women (30-75 years) were randomly selected fro...

journal_title：BMC endocrine disorders

authors： Larsson CA,Gullberg B,Råstam L,Lindblad U

更新日期：2009-06-21 00:00:00

abstract：BACKGROUND:Clinical determination of mid-parental height is an important part of the assessment of a child's growth, however our clinical impression has been that parents cannot be relied upon to accurately report their own heights. Therefore, we conducted this study to assess the accuracy of parental height self-repor...

journal_title：BMC endocrine disorders

authors： Braziuniene I,Wilson TA,Lane AH

更新日期：2007-04-02 00:00:00

abstract：BACKGROUND:Children whose mothers had low thyroid hormone levels during pregnancy have been reported to have decreased cognitive function. The reported research is part of the follow-on study of the Controlled Antenatal Thyroid Screening Study (CATS I), a randomised controlled trial which investigated the impact of tre...

journal_title：BMC endocrine disorders

authors： Hales C,Channon S,Taylor PN,Draman MS,Muller I,Lazarus J,Paradice R,Rees A,Shillabeer D,Gregory JW,Dayan CM,Ludgate M

更新日期：2014-12-12 00:00:00

abstract：BACKGROUND:Diabetes mellitus (DM) is a global health care problem that can impose a substantial economic burden. Diabetic peripheral neuropathy (DPN) is a common microvascular complication of DM that increases the potential for morbidity and disability due to ulceration and amputation. Though there is a significant amo...

journal_title：BMC endocrine disorders

authors： Shiferaw WS,Akalu TY,Work Y,Aynalem YA

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:In order to accurately interpret neonatal thyroid function tests (TFTs), it is necessary to have population specific reference intervals (RIs) as there is significant variation across different populations possibly due to genetic, environmental or analytical issues. Despite the importance of RIs, globally th...

journal_title：BMC endocrine disorders

authors： Omuse G,Kassim A,Kiigu F,Hussain SR,Limbe M

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND:Among patients with type 2 diabetes, insulin intensification to achieve glycemic targets occurs less often than clinically indicated. Barriers to intensification are not well understood. We present patients' baseline characteristics from MOSAIc, a study investigating patient-, physician-, and healthcare envi...

journal_title：BMC endocrine disorders

authors： Polinski JM,Kim SC,Jiang D,Hassoun A,Shrank WH,Cos X,Rodríguez-Vigil E,Suzuki S,Matsuba I,Seeger JD,Eddings W,Brill G,Curtis BH

更新日期：2015-09-09 00:00:00

abstract：BACKGROUND:Most of the patients with type 1 and V hyperlipoproteinemia (HLP) present with symptoms and signs of acute pancreatitis due to marked elevation of triglycerides, but this baby presented with a chest infection, which was later diagnosed as type V HLP on laboratory workup. CASE PRESENTATION:We report a case o...

journal_title：BMC endocrine disorders

authors： Dildar S,Shamsi TS

更新日期：2020-02-11 00:00:00