Abstract：
:Life expectancy is increasing and so is the prevalence of age-related non-communicable diseases (NCDs). Consequently, older people and patients present with multi-morbidities and more complex needs, putting significant pressure on healthcare systems. Effective nutrition interventions could be an important tool to address patient needs, improve clinical outcomes and reduce healthcare costs. Inflammation plays a central role in NCDs, so targeting it is relevant to disease prevention and treatment. The long-chain omega-3 polyunsaturated fatty acids (omega-3 LCPUFAs) docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are known to reduce inflammation and promote its resolution, suggesting a beneficial role in various therapeutic areas. An expert group reviewed the data on omega-3 LCPUFAs in specific patient populations and medical conditions. Evidence for benefits in cognitive health, age- and disease-related decline in muscle mass, cancer treatment, surgical patients and critical illness was identified. Use of DHA and EPA in some conditions is already included in some relevant guidelines. However, it is important to note that data on the effects of omega-3 LCPUFAs are still inconsistent in many areas (e.g., cognitive decline) due to a range of factors that vary amongst the trials performed to date; these factors include dose, timing and duration; baseline omega-3 LCPUFA status; and intake of other nutrients. Well-designed intervention studies are required to optimize the effects of DHA and EPA in specific patient populations and to develop more personalized strategies for their use.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Troesch B,Eggersdorfer M,Laviano A,Rolland Y,Smith AD,Warnke I,Weimann A,Calder PCdoi
10.3390/nu12092555subject
Has Abstractpub_date
2020-08-24 00:00:00issue
9issn
2072-6643pii
nu12092555journal_volume
12pub_type
杂志文章,评审相关文献
Nutrients文献大全abstract：:Tyrosinemia type 1 (TT1) treatment with 2-(2-nitro-4-trifluormethyl-benzyl)-1,3-cyclohexanedione (NTBC) and a phenylalanine-tyrosine restricted diet is associated with low phenylalanine concentrations. Phenylalanine supplementation is prescribed without comprehensive consideration about its effect on metabolic control...
journal_title：Nutrients
pub_type： 杂志文章,多中心研究
doi：10.3390/nu11112816
更新日期：2019-11-18 00:00:00
abstract：:Susceptibility to develop hypertension may be established during early stages of life that include the intrauterine period, infancy and childhood. We recently showed that blood pressure increased when rats reached adulthood when sucrose was ingested for a short-term critical window from postnatal day 12 to 28 in the r...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11020309
更新日期：2019-02-01 00:00:00
abstract：:Prader-Willi syndrome (PWS) is the most common genetic inherited obesity syndrome. Obesity-related complications, mostly related to chronic low-grade systemic inflammation (LGI), are the commonest cause of mortality and morbidity in PWS adults. Phase angle (PhA) is an easy tool to screen a state of LGI in healthy subj...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12072065
更新日期：2020-07-11 00:00:00
abstract：:Dietary flavonoids are vasoactive phytochemicals with promising anti-inflammatory properties. We aimed to assess the associations between baseline intakes of six commonly consumed flavonoid subclasses and 10-year incidence of age-related hearing loss. At baseline, 1691 participants aged 50+ years had information on di...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12113297
更新日期：2020-10-28 00:00:00
abstract：:One of the deadliest cancers among women is a breast cancer. Research has shown that two natural substances occurring in propolis, caffeic acid (CA) and caffeic acid phenethyl ester (CAPE), have significant anticancer effects. The purpose of our in vitro study was to compare cytotoxic activity and migration rate inhib...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu9101144
更新日期：2017-10-19 00:00:00
abstract：:Home Artificial Nutrition (HAN) is a safe and efficacious technique that insures children's reintegration into the family, society and school. Epidemiological data on paediatric HAN in Italy are not available. AIM:to detect the prevalence and incidence of Home Parenteral Nutrition (HPN) and Home Enteral Nutrition (HE...
journal_title：Nutrients
pub_type： 杂志文章,多中心研究
doi：10.3390/nu10091311
更新日期：2018-09-16 00:00:00
abstract：:Bile acids play an active role in fat metabolism and, in high-fat diets, elevated concentrations of fecal bile acids may be related to an increased risk of colorectal cancer. This study investigated concentrations of fecal and serum bile acids in 36 vegans and 36 omnivores. The reduced rank regression was used to iden...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12010047
更新日期：2019-12-23 00:00:00
abstract：:Food resource management (FRM) behaviors are key components within nutrition education programs designed to help food insecure households maximize their food dollars. However, little is known about the association between FRM self-confidence and financial practices with household food insecurity (HFI) among families w...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12082304
更新日期：2020-07-31 00:00:00
abstract：:This study evaluated the effect of linseed incorporation in laying hens' feed (alone or along with a tomato-red pepper mix) on laying hens' egg yolk fatty acids profile, as well as on their atherogenic (IA) and thrombogenic (IT) health lipid indexes, and the ratio between the hypocholesterolemic and hypercholesterolem...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11040813
更新日期：2019-04-10 00:00:00
abstract：:Health claims may contribute to better informed and healthier food choices and to improved industrial competitiveness by marketing foods that support healthier lifestyles in line with consumer preferences. With the more stringent European Union regulation of nutrition and health claims, insights into consumers' health...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu5010082
更新日期：2013-01-10 00:00:00
abstract：:Obesity and iron deficiency (ID) are two of the most common nutritional disorders in the world. In children both conditions deserve particular attention. Several studies revealed an association between obesity and iron deficiency in children and, in some cases, a reduced response to oral supplementation. The connectin...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu7115458
更新日期：2015-11-06 00:00:00
abstract：:Vitamin A or retinol which is the natural precursor of several biologically active metabolites can be considered the most multifunctional vitamin in mammals. Its deficiency is currently, along with protein malnutrition, the most serious and common nutritional disorder worldwide. It is necessary for normal embryonic de...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu6114984
更新日期：2014-11-10 00:00:00
abstract：:Today's industrial food production contributes significantly to environmental degradation. Meat production accounts for the largest impact, including greenhouse gas emissions, land and water use. While food production and consumption are important aspects when addressing climate change, this article focuses predominan...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu9040412
更新日期：2017-04-21 00:00:00
abstract：:Nonalcoholic fatty liver disease (NAFLD) is on the rise worldwide representing a public health issue. Its coexistence with obesity and other metabolic alterations is highly frequent. Therefore, current therapy interventions for NAFLD are mainly focused on progressive weight loss through modulation of overall calorie i...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu12123860
更新日期：2020-12-17 00:00:00
abstract：:Amidst the ongoing societal and economic shifts in the Eastern Mediterranean region (EMR), this study aims at investigating temporal trends in food consumption and nutrient intakes among Lebanese adults, by age and sex. Data were derived from two national cross-sectional surveys conducted in Lebanon during two time pe...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11081738
更新日期：2019-07-27 00:00:00
abstract：:Age-appropriate feeding practice (ADF) during early childhood are vital for optimal nutrition. This longitudinal study determined the effect of selected risk factors and ADF, as described by the National Nutritional Recommendations, on linear and ponderal growth of children below 24 months of age. Weight and length me...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12010012
更新日期：2019-12-19 00:00:00
abstract：:The synergies and cumulative effects among different foods and nutrients are what produce the benefits of a healthy dietary pattern. Diets and dietary patterns are a major environmental factor that we are exposed to several times a day. People can learn how to control this behavior in order to promote healthy living a...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu8040218
更新日期：2016-04-13 00:00:00
abstract：:The present study aimed to assess energy intake, nutrient profile and food sources in Spanish children participating in the EsNuPI ("Estudio Nutricional en Población Infantil Española") study. Plausibility of energy intake and adequacy of nutrient intakes to international recommendations were analyzed in a final sampl...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12040893
更新日期：2020-03-25 00:00:00
abstract：:β-hydroxybutyrate (β-OHB) has been shown to exert an anti-inflammatory activity. Apolipoprotein-E (ApoE) is strongly associated with atherosclerosis and Alzheimer's disease (AD). This study aimed to explore the therapeutic effect of β-OHB in the brain and the aorta of high-fat diet (HFD)-fed ApoE-deficient mice. We fo...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12020471
更新日期：2020-02-13 00:00:00
abstract：:Qualified health claims (QHC) describe diet-disease relationships and summarize the quality and strength of evidence for a claim. Companies assert that QHCs increase sales and take legal action to ensure claims reflect their interests. Yet, there is no empirical evidence that QHCs influence consumers. Using green tea ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11040921
更新日期：2019-04-24 00:00:00
abstract：BACKGROUND:Malnutrition is associated with poor outcomes in patients with cancer, heart failure and chronic kidney disease. This study aimed to investigate the predictive value of the Controlling Nutritional Status (CONUT) score in coronary artery disease (CAD) patients. METHODS:We recruited a cohort of 3118 patients ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12051295
更新日期：2020-05-02 00:00:00
abstract：:The relationship between vitamin D status, calcium intake and the risk of developing type 2 diabetes (T2D) is a topic of growing interest. One of the most interesting non-skeletal functions of vitamin D is its potential role in glucose homeostasis. This possible association is related to the secretion of insulin by pa...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu11030642
更新日期：2019-03-16 00:00:00
abstract：:Gene-environment (G × E) interactions involving job stress and mental health on risk factors of cardiovascular disease (CVD) are minimally explored. This study examined the association and G × E interaction effects of vascular endothelial growth factor receptor-2 (VEGFR-2) gene polymorphisms (rs1870377, rs2071559) on ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11051140
更新日期：2019-05-22 00:00:00
abstract：:The present study compares the effects of two dietary strawberry extracts rich in monomeric (ME) or dimeric (DE) ellagitannins (ETs) on gastrointestinal, blood and tissue biomarkers in Wistar rats fed high-fructose diets. Both strawberry extracts beneficially affect the antioxidant status and lipid profile of the live...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10040445
更新日期：2018-04-04 00:00:00
abstract：:Hearing loss (HL) is a major public health problem. Nutritional factors can affect a variety of diseases, such as HL, in humans. Thus far, several studies have evaluated the association between nutrition and hearing. These studies found that the incidence of HL was increased with the lack of single micro-nutrients suc...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu11020307
更新日期：2019-02-01 00:00:00
abstract：:Despite several papers having been published on the association between adiposity and the risk of metabolic syndrome (MetS), it is still difficult to determine unambiguously which of the indices of nutritional status is the best to identify MetS. The aim of this study was to analyze the ability of six anthropometric i...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11112598
更新日期：2019-10-29 00:00:00
abstract：:Glycerol monolaurate (GML) has potent antimicrobial and anti-inflammatory activities. The present study aimed to assess the dose-dependent antimicrobial-effects of GML on the gut microbiota, glucose and lipid metabolism and inflammatory response in C57BL/6 mice. Mice were fed on diets supplemented with GML at dose of ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11091981
更新日期：2019-08-22 00:00:00
abstract：:Oleuropein (OLE) is the major phenolic secoiridoid of olive tree leaves, and its antioxidant and anti-inflammatory activities have been demonstrated in in vitro and in vivo animal models. The aim of this study was to investigate the activity of OLE in the colonic mucosa from patients with ulcerative colitis (UC). Biop...
journal_title：Nutrients
pub_type： 临床试验,杂志文章
doi：10.3390/nu9040391
更新日期：2017-04-15 00:00:00
abstract：:Non-alcoholic fatty liver disease (NAFLD) is a manifestation of metabolic syndrome closely linked to dyslipidemia and gut microbiome dysbiosis. Bilberry anthocyanins (BA) have been reported to have preventive effects against metabolic syndrome. This study aimed to investigate the protective effects and mechanisms of B...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12113252
更新日期：2020-10-23 00:00:00
abstract：:Our aim is evaluating the changes in weight and dietary habits in a sample of outpatients with obesity after 1 month of enforced lockdown during the COVID-19 pandemic in Northern Italy. In this observational retrospective study, the patients of our Obesity Unit were invited to answer to a 12-question multiple-choice q...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12072016
更新日期：2020-07-07 00:00:00
