Abstract:
:Fermented rice bran (FRB), a prospective supplement, has been proven to ameliorate certain medical conditions. However, its nutraceutical effect on muscle atrophy has never been investigated. The present study aimed to evaluate the effect of FRB on muscle atrophy in a streptozotocin (STZ)-induced diabetic rat model. Three groups of Sprague-Dawley rats, namely the control, STZ, and FRB groups, were treated as follows. The diabetic groups (STZ and FRB) were injected intraperitoneally with STZ (40 mg/kg BW), whereas the control group was injected with the vehicle. The STZ and control groups were fed the AIN93M diet, and the FRB group was fed 10% of FRB based on the AIN93M diet. The diabetic groups had reduced muscle size compared to the control group; however, these changes were alleviated in the FRB group. Moreover, the FRB group had a significantly lower expression of FBXO32/Atrogin-1 and TRIM63/MuRF1 (p < 0.05) due to blocked NF-κB activation. In conclusion, the anti-inflammatory effect of FRB may be beneficial for ameliorating muscle atrophy in diabetic conditions.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Rusbana TB,Agista AZ,Saputra WD,Ohsaki Y,Watanabe K,Ardiansyah A,Budijanto S,Koseki T,Aso H,Komai M,Shirakawa Hdoi
10.3390/nu12082409subject
Has Abstractpub_date
2020-08-12 00:00:00issue
8issn
2072-6643pii
nu12082409journal_volume
12pub_type
杂志文章相关文献
Nutrients文献大全abstract::Reducing salt intake is a cost-effective public health intervention to reduce the global burden of non-communicable disease (NCDs). Ultra-processed foods contribute ~80% of dietary salt in high income countries, and are becoming prominent in low-middle income countries. Instant noodle consumption is particularly high ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9060612
更新日期:2017-06-16 00:00:00
abstract::Docosahexaenoic acid (DHA) is a structural constituent of membranes specifically in the central nervous system. Its accumulation in the fetal brain takes place mainly during the last trimester of pregnancy and continues at very high rates up to the end of the second year of life. Since the endogenous formation of DHA ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu8010006
更新日期:2016-01-04 00:00:00
abstract:OBJECTIVE:Type 2 diabetes mellitus (T2DM) is thought to arise from the complex interplay between genetic and environmental factors. It is important to identify modifiable risk factors that may help to reduce the risk of diabetes. Data on salt intake and the risk of type 2 diabetes are limited. The aim of this study was...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9010067
更新日期:2017-01-13 00:00:00
abstract::Hyperhomocysteinemia (HHcy) is a risk factor for atherosclerosis through mechanisms which are still incompletely defined. One possible mechanism involves the hypomethylation of the nuclear histone proteins to favor the progression of atherosclerosis. In previous cell studies, hypomethylating stress decreased a specifi...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12082182
更新日期:2020-07-23 00:00:00
abstract::A low Omega-3 Index (eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in erythrocytes) is associated with cardiac, cerebral, and other health issues. Intake of EPA and DHA, but not of alpha-linolenic acid (ALA), increases the Omega-3 Index. We investigated bioavailability, safety, palatability and tolerabili...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu9060629
更新日期:2017-06-19 00:00:00
abstract::In recent years, the concept of the health benefits of synergistic dietary patterns as opposed to individual foods or food constituents has been developed. The aim of this study was to determine whether nut consumption is associated with healthier nutrition and lifestyle. The research was based on complete data obtain...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11061410
更新日期:2019-06-22 00:00:00
abstract::(1) Background: Pregnancy outcomes for both mother and child are affected by many environmental factors. The importance of pregnancy for 'early life programming' is well established and maternal nutrition is an important factor contributing to a favourable environment for developing offspring. We aim to assess whether...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11051098
更新日期:2019-05-17 00:00:00
abstract::Insufficient dietary intake, micronutrient deficiencies, and infection may result in malnutrition. In Zambia, an estimated 14% of women are vitamin A-deficient, ~50% are anemic, 10% are underweight, and 23% are overweight/obese. A cross-sectional survey determined food and nutrient intakes of randomly selected Zambian...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11020288
更新日期:2019-01-29 00:00:00
abstract::Energy intake, and the foods and beverages contributing to that, are considered key to understanding the high obesity prevalence worldwide. The relative contributions of energy intake and expenditure to the obesity epidemic, however, remain poorly defined in Spain. The purpose of this study was to contribute to updati...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7064739
更新日期:2015-06-12 00:00:00
abstract::Mechanistic data have revealed a key role for selenium (Se) and selenoproteins in biological pathways known to be altered in multifactorial diseases, such as cellular maintenance, response to oxidative stress and correct protein folding. Although epidemiological studies indicate that low Se intake is linked to increas...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu7053621
更新日期:2015-05-15 00:00:00
abstract:BACKGROUND:Nutritional interventions may have positive effects on sarcopenia and body composition. OBJECTIVE:to evaluate the effectiveness of extra virgin olive oil (EVOO) consumption and a healthy traditional Brazilian diet (DieTBra) on improving sarcopenia indicators and reducing total body fat in severe obesity. M...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12051498
更新日期:2020-05-21 00:00:00
abstract::Soy is a basic food ingredient of traditional Asian cuisine used for thousands of years. In Western countries, soybeans have been introduced about a hundred years ago and recently they are mainly used for surrogate foods production. Soy and soy foods are common nutritional solutions for vegetarians, due to their high ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10010043
更新日期:2018-01-05 00:00:00
abstract::Evidence indicates that many forms of fructose-induced metabolic disturbance are associated with oxidative stress and mitochondrial dysfunction. Mitochondria are prominent targets of oxidative damage; however, it is not clear whether mitochondrial DNA (mtDNA) damage and/or its lack of repair are events involved in met...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9040323
更新日期:2017-03-24 00:00:00
abstract::To clarify the anti-obesity effect of Allomyrina dichotoma larvae (ADL), we previously reported that ADL block adipocyte differentiation on 3T3-L1 cell lines through downregulation of transcription factors, such as peroxisome proliferator-activated receptor-γ (PPARG) and CCAAT/enhancer binding protein-α (CEBPA). In th...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7031978
更新日期:2015-03-17 00:00:00
abstract::There is currently little information on changes in vitamin D status during pregnancy and its predictors. The aim was to study the determinants of change in vitamin D status during pregnancy and of vitamin D deficiency (<30 nmol/L) in early pregnancy. Blood was drawn in the first (T1) and third trimester (T3). Serum 2...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8100655
更新日期:2016-10-22 00:00:00
abstract::Poor diet quality and obesity, especially abdominal obesity, have been associated with systemic inflammation. The neutrophil-to-lymphocyte Ratio (NLR) is an available and inexpensive inflammation biomarker. The aim of the present study was to determine the association of dietary patterns and obesity with an inflammato...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12030855
更新日期:2020-03-23 00:00:00
abstract::The aim of this work was to assess the accuracy of automatic macronutrient and calorie counting based on voice descriptions of meals provided by people with unstable type 1 diabetes using the developed expert system (VoiceDiab) in comparison with reference counting made by a dietitian, and to evaluate the impact of in...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10040518
更新日期:2018-04-21 00:00:00
abstract::Probiotics possibly affect local and systemic immune reactions and maintain the intestinal immune homeostasis in healthy individuals and patients with diseases such as irritable bowel syndrome (IBS). In this single-center, blinded trial, we enrolled 40 individuals (20 patients with IBS and 20 healthy individuals) whos...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061706
更新日期:2020-06-07 00:00:00
abstract::Despite several reports on the relationship between metabolic and neurodegenerative diseases, the effect of a high-sugar diet (HSD) on brain function is still unknown. Given the crucial role of oxidative stress in the pathogenesis of these disorders, this study was the first to compare the effect of an HSD on the acti...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12103181
更新日期:2020-10-18 00:00:00
abstract::Type 2 diabetes mellitus (T2DM) is associated with increased total plasma free fatty acid (FFA) concentrations and an elevated risk of cardiovascular disease. The exact mechanisms by which the plasma FFA profile of subjects with T2DM changes is unclear, but it is thought that dietary fats and changes to lipid metaboli...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu11092022
更新日期:2019-08-28 00:00:00
abstract::Metabolic syndrome (MetS) is defined as a cluster of metabolic alterations such as abdominal obesity, dyslipidemias, elevated fasting glucose, and hypertension. Studies on the association between egg consumption and MetS are limited and inconsistent. A cross-sectional analysis was conducted to examine the association ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9070687
更新日期:2017-07-02 00:00:00
abstract::Advanced glycation endproducts (AGEs) can be found in protein- and sugar-rich food products processed at high temperatures, which make up a vast amount of the Western diet. The effect of AGE-rich food products on human health is not yet clear and controversy still exists due to possible contamination of samples with e...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10121868
更新日期:2018-12-02 00:00:00
abstract::Awareness and knowledge of nutrient-dense foods are important for older adults to help them make dietary choices that support a food-first approach to healthy aging. This is especially important since age is a major risk factor for chronic disease and the proportion of older adults in North America is increasing. Bean...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11112680
更新日期:2019-11-05 00:00:00
abstract::We examined the impact of APOE genotype on plasma lipids and glucose in a secondary analysis of data from a five-arm, randomised controlled, parallel dietary intervention trial ('RISCK' study), to investigate the impact of replacing saturated fatty acids (SFA) with either monounsaturated fat (MUFA) or carbohydrate of ...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu10101524
更新日期:2018-10-17 00:00:00
abstract::Carrots are consumed worldwide. Several meta-analysis studies on carrot consumption have indicated that carrots play a central role as a protecting vegetable against development of different types of cancers. A cancer-preventive role of carrots is plausible because they are the main dietary source of the bioactive pol...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12020332
更新日期:2020-01-27 00:00:00
abstract::Responsive feeding is crucial to the formation of life-long healthy eating behavior. Few studies have examined maternal responsive feeding in early infancy among a Chinese population. This prospective study describes maternal responsive feeding and factors associated with maternal responsive feeding, with emphasis on ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061766
更新日期:2020-06-12 00:00:00
abstract::Dietary habits in adolescence persist into adulthood; thus, it is important to identify the factors that influence adolescent diet and establish a healthy diet. This study aimed to examine the association between mothers' nutrition knowledge and their children's nutrient intake inadequacy among Japanese junior high sc...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12092801
更新日期:2020-09-13 00:00:00
abstract::The Recommended Dietary Allowance (RDA) is the nutrient intake considered to be sufficient to meet the requirements of 97.5% of the population. Recent reports revealed a statistical error in the calculation of the RDA for vitamin D opening the question of what the recommendation should be. We took a dual approach to a...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7125527
更新日期:2015-12-04 00:00:00
abstract::This study aimed to detect the association of the MADD-FOLH1 single nucleotide polymorphisms (SNPs) and their haplotypes with the risk of coronary heart disease (CHD) and ischemic stroke (IS) in a Chinese Han population. Six SNPs of rs7395662, rs326214, rs326217, rs1051006, rs3736101, and rs7120118 were genotyped in 5...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8040208
更新日期:2016-04-08 00:00:00
abstract::Providing information to consumers through the label is a means for food companies to inform consumers about product's attributes, including the country of origin (COO). In the EU, COO labeling has been made mandatory for several categories of food products, to enable consumers to make informed choices at the point of...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12072150
更新日期:2020-07-19 00:00:00