Effects of Extra Virgin Olive Oil (EVOO) and the Traditional Brazilian Diet on Sarcopenia in Severe Obesity: A Randomized Clinical Trial.

Abstract:

BACKGROUND:Nutritional interventions may have positive effects on sarcopenia and body composition. OBJECTIVE:to evaluate the effectiveness of extra virgin olive oil (EVOO) consumption and a healthy traditional Brazilian diet (DieTBra) on improving sarcopenia indicators and reducing total body fat in severe obesity. METHODS:A randomized controlled trial registered at ClinicalTrials.gov (NCT02463435) conducted with 111 severely obese participants randomized into three treatment groups-(1) EVOO (52 mL/day), (2) DieTBra, (3) DieTBra + EVOO (52 mL/day)-for 12 weeks. Body composition was assessed by dual-energy X-ray absorptiometry and sarcopenia by walking speed and handgrip strength. RESULTS:Significant reductions in total body fat (p = 0.041) and body weight (p = 0.003) were observed in the DieTBra group. In the DietBra + olive oil group there was also a significant reduction in body weight (0.001) compared to the olive oil-only group. ANCOVA analyses showed reductions in total body fat in the DieTBra (p = 0.016) and DieTBra + olive oil (p = 0.004) groups. Individuals in the DieTBra group had significant improvements in their walking speed (p = 0.042) and handgrip strength (p = 0.044). CONCLUSIONS:DieTBra contributes to improvements in handgrip strength, walking speed, and total body fat in severely obese adults. The major study was registered at ClinicalTrials.gov (NCT02463435).

journal_name

Nutrients

journal_title

Nutrients

authors

Aparecida Silveira E,Danésio de Souza J,Dos Santos Rodrigues AP,Lima RM,de Souza Cardoso CK,de Oliveira C

doi

10.3390/nu12051498

subject

Has Abstract

pub_date

2020-05-21 00:00:00

issue

5

issn

2072-6643

pii

nu12051498

journal_volume

12

pub_type

杂志文章
  • Bioavailability of Sulforaphane Following Ingestion of Glucoraphanin-Rich Broccoli Sprout and Seed Extracts with Active Myrosinase: A Pilot Study of the Effects of Proton Pump Inhibitor Administration.

    abstract::We examined whether gastric acidity would affect the activity of myrosinase, co-delivered with glucoraphanin (GR), to convert GR to sulforaphane (SF). A broccoli seed and sprout extract (BSE) rich in GR and active myrosinase was delivered before and after participants began taking the anti-acid omeprazole, a potent pr...

    journal_title:Nutrients

    pub_type: 临床试验,杂志文章

    doi:10.3390/nu11071489

    authors: Fahey JW,Wade KL,Stephenson KK,Panjwani AA,Liu H,Cornblatt G,Cornblatt BS,Ownby SL,Fuchs E,Holtzclaw WD,Cheskin LJ

    更新日期:2019-06-29 00:00:00

  • Gastroprotective efficacy and safety evaluation of scoparone derivatives on experimentally induced gastric lesions in rodents.

    abstract::This study investigated the gastroprotective efficacy of synthesized scoparone derivatives on experimentally induced gastritis and their toxicological safety. Six scoparone derivatives were synthesized and screened for gastroprotective activities against HCl/ethanol- and indomethacin-induced gastric ulcers in rats. Am...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu7031945

    authors: Son DJ,Lee GR,Oh S,Lee SE,Choi WS

    更新日期:2015-03-13 00:00:00

  • Prevalence and Predictors of Dietary and Nutritional Supplement Use in the Australian Army: A Cross-Sectional Survey.

    abstract::Dietary supplements (DSs) and nutritional supplements (NSs) can enhance performance, recovery or training adaptations, however, some substances, dosages, and usage protocols are unsafe. Knowledge of the type and extent of use within populations enables strategies to be formulated to promote safe and effective use (whe...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu11071462

    authors: Baker B,Probert B,Pomeroy D,Carins J,Tooley K

    更新日期:2019-06-27 00:00:00

  • Biological Activity of New Cichoric Acid-Metal Complexes in Bacterial Strains, Yeast-Like Fungi, and Human Cell Cultures In Vitro.

    abstract::Cichoric acid (CA) belongs to the group of polyphenols, which occurs in a variety of plant species and it is characterized by anticancer, antibacterial, and antiviral properties. Selected polyphenols have the ability to combine with metal ions to form chelate complexes that reveal greater biological activity than free...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu12010154

    authors: Jabłońska-Trypuć A,Wydro U,Wołejko E,Świderski G,Lewandowski W

    更新日期:2020-01-06 00:00:00

  • β-Cyclodextrin Does not Alter the Bioaccessibility and the Uptake by Caco-2 Cells of Olive By-Product Phenolic Compounds.

    abstract::Alperujo-a two-phase olive mill waste that is composed of olive vegetation water and solid skin, pulp, and seed fragments - is a highly valuable olive by-product due to its high content in phenolic compounds. In this study, we assessed whether β-cyclodextrin (β-CD), which is used to extract and protect alpejuro phenol...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu10111653

    authors: Malapert A,Tomao V,Margier M,Nowicki M,Gleize B,Dangles O,Reboul E

    更新日期:2018-11-03 00:00:00

  • A New Approach to Assess Lifetime Dietary Patterns Finds Lower Consumption of Animal Foods with Aging in a Longitudinal Analysis of a Health-Oriented Adventist Population.

    abstract::Life-course diet patterns may impact risk of disease, but little is known about dietary trends with aging. In a retrospective longitudinal analysis we estimated lifetime intake of animal products and adherence to vegetarian dietary patterns among 51,082 Adventist Health Study-2 (AHS-2) subjects using data from a relia...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu9101118

    authors: Martins MCT,Jaceldo-Siegl K,Orlich M,Fan J,Mashchak A,Fraser GE

    更新日期:2017-10-13 00:00:00

  • Hydrolysis of the rutinose-conjugates flavonoids rutin and hesperidin by the gut microbiota and bifidobacteria.

    abstract::Flavonols and flavanones are polyphenols exerting many healthy biological activities. They are often glycosylated by rutinose, which hampers absorption in the small intestine. Therefore they require the gut microbiota to release the aglycone and enable colonic absorption. The role of the gut microbiota and bifidobacte...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu7042788

    authors: Amaretti A,Raimondi S,Leonardi A,Quartieri A,Rossi M

    更新日期:2015-04-14 00:00:00

  • Is Trabecular Bone Score Valuable in Bone Microstructure Assessment after Gastric Bypass in Women with Morbid Obesity?

    abstract:INTRODUCTION:The effects of bariatric surgery on skeletal health raise many concerns. Trabecular bone score (TBS) is obtained through the analysis of lumbar spine dual X-ray absorptiometry (DXA) images and allows an indirect assessment of skeletal microarchitecture (MA). The aim of our study was to evaluate the changes...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu9121314

    authors: Marengo AP,Guerrero Pérez F,San Martín L,Monseny R,Casajoana A,Valera R,Virgili N,Simó Servat A,Prats A,Gómez-Vaquero C,Vilarrasa N

    更新日期:2017-12-02 00:00:00

  • Effects of Anserine/Carnosine Supplementation on Mild Cognitive Impairment with APOE4.

    abstract:BACKGROUND:Oral supplementation of anserine/carnosine helps preserve cognitive functions in healthy older adults. Mild cognitive impairment (MCI) is a transition between cognitive-normal and dementia. Therefore, it needs to investigate whether anserine/carnosine supplementation (ACS) has effects on subjects with MCI. ...

    journal_title:Nutrients

    pub_type: 杂志文章,随机对照试验

    doi:10.3390/nu11071626

    authors: Masuoka N,Yoshimine C,Hori M,Tanaka M,Asada T,Abe K,Hisatsune T

    更新日期:2019-07-17 00:00:00

  • Altered Red Blood Cell Membrane Fatty Acid Profile in Cancer Patients.

    abstract::The fatty acid (FA) composition of red blood cell (RBC) membrane phospholipids of cancer patients can reflect tumor status, dietary intakes, and cancer type or therapy. However, the characteristic membrane profiles have so far not yet defined as a potential biomarker to monitor disease evolution. The present work prov...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu10121853

    authors: Amézaga J,Arranz S,Urruticoechea A,Ugartemendia G,Larraioz A,Louka M,Uriarte M,Ferreri C,Tueros I

    更新日期:2018-12-01 00:00:00

  • Oligonol, a Low-Molecular Weight Polyphenol Derived from Lychee, Alleviates Muscle Loss in Diabetes by Suppressing Atrogin-1 and MuRF1.

    abstract::Stimulation of the ubiquitin-proteasome pathway-especially E3 ubiquitin ligases Atrogin-1 and MuRF1-is associated with muscle loss in diabetes. Elevated lipid metabolites impair myogenesis. Oligonol, a low molecular weight polyphenol derived from lychee, exhibited anti-diabetic and anti-obesity properties, suggesting ...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu9091040

    authors: Liu HW,Chen YJ,Chang YC,Chang SJ

    更新日期:2017-09-20 00:00:00

  • Biological variability and impact of oral contraceptives on vitamins B(6), B(12) and folate status in women of reproductive age.

    abstract::Vitamins B(6), B(12) and folate play crucial metabolic roles especially during the reproductive years for women. There is limited reporting of within-subject variability of these vitamins. This study aimed to determine the within and between subject variability in serum vitamins B(6), B(12), folate and erythrocyte fol...

    journal_title:Nutrients

    pub_type: 杂志文章,随机对照试验

    doi:10.3390/nu5093634

    authors: McArthur JO,Tang H,Petocz P,Samman S

    更新日期:2013-09-16 00:00:00

  • Bioelectrical Impedance Phase Angle as an Indicator of Malnutrition in Hospitalized Children with Diagnosed Inflammatory Bowel Diseases-A Case Control Study.

    abstract::The phase angle (PhA) seems to be a reliable screening tool for the identification of malnutrition risk in hospitalized children with inflammatory bowel disease (IBD). The aim of the present study was to assess the body composition and nutritional status of hospitalized children and adolescents with IBD by using bioel...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu10040499

    authors: Więch P,Dąbrowski M,Bazaliński D,Sałacińska I,Korczowski B,Binkowska-Bury M

    更新日期:2018-04-17 00:00:00

  • The Effect of Alcohol on Cardiovascular Risk Factors: Is There New Information?

    abstract::The effects of alcohol on cardiovascular health are heterogeneous and vary according toconsumption dose and pattern. These effects have classically been described as having a J-shapedcurve, in which low-to-moderate consumption is associated with less risk than lifetime abstention,and heavy drinkers show the highest ri...

    journal_title:Nutrients

    pub_type: 杂志文章,评审

    doi:10.3390/nu12040912

    authors: Minzer S,Losno RA,Casas R

    更新日期:2020-03-27 00:00:00

  • Egg Consumption and Risk of Metabolic Syndrome in Korean Adults: Results from the Health Examinees Study.

    abstract::Metabolic syndrome (MetS) is defined as a cluster of metabolic alterations such as abdominal obesity, dyslipidemias, elevated fasting glucose, and hypertension. Studies on the association between egg consumption and MetS are limited and inconsistent. A cross-sectional analysis was conducted to examine the association ...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu9070687

    authors: Shin S,Lee HW,Kim CE,Lim J,Lee JK,Lee SA,Kang D

    更新日期:2017-07-02 00:00:00

  • Accuracy of Automatic Carbohydrate, Protein, Fat and Calorie Counting Based on Voice Descriptions of Meals in People with Type 1 Diabetes.

    abstract::The aim of this work was to assess the accuracy of automatic macronutrient and calorie counting based on voice descriptions of meals provided by people with unstable type 1 diabetes using the developed expert system (VoiceDiab) in comparison with reference counting made by a dietitian, and to evaluate the impact of in...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu10040518

    authors: Ladyzynski P,Krzymien J,Foltynski P,Rachuta M,Bonalska B

    更新日期:2018-04-21 00:00:00

  • Usual Dietary Intake, Nutritional Adequacy and Food Sources of Calcium, Phosphorus, Magnesium and Vitamin D of Spanish Children Aged One to

    abstract::Bone problems in the population begin to be establish in childhood. The present study aims to assess the usual calcium, phosphorus, magnesium, and vitamin D intakes, along with the food sources of these nutrients, in Spanish children participating in the EsNuPI (Estudio Nutricional en Población Infantil Española) stud...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu12061787

    authors: Cuadrado-Soto E,López-Sobaler AM,Jiménez-Ortega AI,Aparicio A,Bermejo LM,Hernández-Ruiz Á,Lara Villoslada F,Leis R,Martínez de Victoria E,Moreno JM,Ruiz-López MD,Soto-Méndez MJ,Valero T,Varela-Moreiras G,Gil Á,Ortega RM

    更新日期:2020-06-16 00:00:00

  • Maternal Folic Acid Deficiency Is Associated to Developing Nasal and Palate Malformations in Mice.

    abstract::Craniofacial development requires extremely fine-tuned developmental coordination of multiple specialized tissues. It has been evidenced that a folate deficiency (vitamin B9), or its synthetic form, folic acid (FA), in maternal diet could trigger multiple craniofacial malformations as oral clefts, tongue, or mandible ...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu13010251

    authors: Maldonado E,Martínez-Sanz E,Partearroyo T,Varela-Moreiras G,Pérez-Miguelsanz J

    更新日期:2021-01-16 00:00:00

  • Efficacy of Polygonatum sibiricum on Mild Insomnia: A Randomized Placebo-Controlled Trial.

    abstract::Polygonatum sibiricum (PS) rhizome, which contains glyceryl-1-monolinoleate as its primary active component, has been shown to improve insomnia in animal models. Based on these findings, we aimed to investigate the safety and efficacy of PS rhizome extract in improving sleep quality in individuals with mild insomnia. ...

    journal_title:Nutrients

    pub_type: 杂志文章,随机对照试验

    doi:10.3390/nu11081719

    authors: Ha E,Hong H,Kim TD,Hong G,Lee S,Kim S,Kim N,Jeon SD,Ahn CW,Kim HJ,Lee YJ,Yoon S,Kim GH,Kim J

    更新日期:2019-07-25 00:00:00

  • Solid Dispersion of Resveratrol Supported on Magnesium DiHydroxide (Resv@MDH) Microparticles Improves Oral Bioavailability.

    abstract::Resveratrol, because of its low solubility in water and its high membrane permeability, is collocated in the second class of the biopharmaceutical classification system, with limited bioavailability due to its dissolution rate. Solid dispersion of resveratrol supported on Magnesium DiHydroxide (Resv@MDH) was evaluated...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu10121925

    authors: Spogli R,Bastianini M,Ragonese F,Iannitti RG,Monarca L,Bastioli F,Nakashidze I,Brecchia G,Menchetti L,Codini M,Arcuri C,Mancinelli L,Fioretti B

    更新日期:2018-12-05 00:00:00

  • Distribution of selenium and oxidative stress in breast tumor-bearing mice.

    abstract::The present study investigated the effects of breast tumors on the blood and tissue distribution of essential trace mineral selenium (Se), and oxidative stress status of mice. Female 10-week-old BALB/cByJNarl mice were randomly assigned into control (CNL) and breast tumor-bearing (TB) groups. TB mice were injected sub...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu5020594

    authors: Guo CH,Hsia S,Chen PC

    更新日期:2013-02-20 00:00:00

  • Blind Analysis of Food-Related IgG Identifies Five Possible Nutritional Clusters for the Italian Population: Future Implications for Pregnancy and Lactation.

    abstract:BACKGROUND:The influence of diet in pregnant women on the immune tolerance process is intricate. Food-specific immunoglobulin G (IgG) was associated with exposure to particular food antigens. The IgG antibodies can cross the placental barrier and enter into the colostrum, and maternal IgG is amply present in breast mil...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu11051096

    authors: Piuri G,Ferrazzi E,Speciani AF

    更新日期:2019-05-17 00:00:00

  • An Anthocyanin-Rich Extract Obtained from Portuguese Blueberries Maintains Its Efficacy in Reducing Microglia-Driven Neuroinflammation after Simulated Digestion.

    abstract::Dietary polyphenols are multi-target compounds that have been considered promising candidates in strategies for the mitigation of neurological diseases, acting particularly through reduction of microglia-driven neuroinflammation. In this study, an anthocyanin-rich extract obtained from Portuguese blueberries was subje...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu12123670

    authors: Serra D,Henriques JF,Serra T,Bento Silva A,Bronze MR,Dinis TCP,Almeida LM

    更新日期:2020-11-28 00:00:00

  • Evaluating the Impact of Different Hypercaloric Diets on Weight Gain, Insulin Resistance, Glucose Intolerance, and its Comorbidities in Rats.

    abstract::Animal experimentation has a long history in the study of metabolic syndrome-related disorders. However, no consensus exists on the best models to study these syndromes. Knowing that different diets can precipitate different metabolic disease phenotypes, herein we characterized several hypercaloric rat models of obesi...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu11061197

    authors: Melo BF,Sacramento JF,Ribeiro MJ,Prego CS,Correia MC,Coelho JC,Cunha-Guimaraes JP,Rodrigues T,Martins IB,Guarino MP,Seiça RM,Matafome P,Conde SV

    更新日期:2019-05-28 00:00:00

  • A Scoping Review of Interactions between Omega-3 Long-Chain Polyunsaturated Fatty Acids and Genetic Variation in Relation to Cancer Risk.

    abstract::This scoping review examines the interaction of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) and genetic variants of various types of cancers. A comprehensive search was performed to identify controlled and observational studies conducted through August 2017. Eighteen unique studies were included: breast...

    journal_title:Nutrients

    pub_type: 杂志文章,评审

    doi:10.3390/nu12061647

    authors: Yurko-Mauro K,Van Elswyk M,Teo L

    更新日期:2020-06-02 00:00:00

  • In "High-Risk" Infants with Sufficient Vitamin D Status at Birth, Infant Vitamin D Supplementation Had No Effect on Allergy Outcomes: A Randomized Controlled Trial.

    abstract::Lower vitamin D status at birth and during infancy has been associated with increased incidence of eczema and food allergies. The aim of this study was to investigate the effect of early infancy vitamin D supplementation on allergic disease outcomes in infants at "hereditary risk" of allergic disease, but who had suff...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu12061747

    authors: Rueter K,Jones AP,Siafarikas A,Lim EM,Prescott SL,Palmer DJ

    更新日期:2020-06-11 00:00:00

  • Dietary Protein and Muscle in Aging People: The Potential Role of the Gut Microbiome.

    abstract::Muscle mass, strength, and physical function are known to decline with age. This is associated with the development of geriatric syndromes including sarcopenia and frailty. Dietary protein is essential for skeletal muscle function. Resistance exercise appears to be the most beneficial form of physical activity for pre...

    journal_title:Nutrients

    pub_type: 杂志文章,评审

    doi:10.3390/nu10070929

    authors: Ni Lochlainn M,Bowyer RCE,Steves CJ

    更新日期:2018-07-20 00:00:00

  • Higher Polygenetic Predisposition for Asthma in Cow's Milk Allergic Children.

    abstract::Cow's milk allergy (CMA) is an early-onset allergy of which the underlying genetic factors remain largely undiscovered. CMA has been found to co-occur with other allergies and immunological hypersensitivity disorders, suggesting a shared genetic etiology. We aimed to (1) investigate and (2) validate whether CMA childr...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu10111582

    authors: Jansen PR,Petrus NCM,Venema A,Posthuma D,Mannens MMAM,Sprikkelman AB,Henneman P

    更新日期:2018-10-27 00:00:00

  • Strategies to Address the Complex Challenge of Improving Regional and Remote Children's Fruit and Vegetable Consumption.

    abstract::Fruit and vegetables (F&V) are imperative for good health, yet less than one per cent of Australian children consume these food groups in sufficient quantities. As guided by Social Cognitive Theory (SCT), this paper aimed to: (i) understand key informant perspectives of the amount, types and quality of F&V consumed by...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu10111603

    authors: Godrich SL,Davies CR,Darby J,Devine A

    更新日期:2018-11-01 00:00:00

  • Erucic Acid (22:1n-9) in Fish Feed, Farmed, and Wild Fish and Seafood Products.

    abstract::The European Food Safety Authority (EFSA) published a risk assessment of erucic acid (22:1n-9) in 2016, establishing a Tolerable Daily Intake (TDI) for humans of 7 mg kg-1 body weight per day. This report largely excluded the contribution of erucic acid from fish and seafood, due to this fatty acid often not being rep...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu10101443

    authors: Sissener NH,Ørnsrud R,Sanden M,Frøyland L,Remø S,Lundebye AK

    更新日期:2018-10-05 00:00:00