Impact of individual background on the unmet needs of cancer survivors and caregivers - a mixed-methods analysis.

abstract：BACKGROUND:In Chile, more than 500 women die every year from cervical cancer, and a majority of Chilean women are not up-to-date with their Papanicolau (Pap) test. Mobile health has great potential in many health areas, particularly in health promotion and prevention. There are no randomized controlled trials in Latin ...

journal_title：BMC cancer

authors： Momany MC,Martinez-Gutierrez J,Soto M,Capurro D,Ciampi F,Thompson B,Puschel K

更新日期：2017-12-13 00:00:00

abstract：BACKGROUND:Treatment standard for patients with primary glioblastoma (GBM) is combined radiochemotherapy with temozolomide (TMZ). Radiation is delivered up to a total dose of 60 Gy using photons. Using this treatment regimen, overall survival could be extended significantly however, median overall survival is still onl...

journal_title：BMC cancer

authors： Combs SE,Kieser M,Rieken S,Habermehl D,Jäkel O,Haberer T,Nikoghosyan A,Haselmann R,Unterberg A,Wick W,Debus J

更新日期：2010-09-06 00:00:00

abstract：BACKGROUND:Bevacizumab, an antibody neutralizing Vascular Endothelial Growth Factor (VEGF), is licensed for the management of patients with advanced colon cancer. However, tumor biomarkers identifying the molecular tumor subsets most amenable to angiogenesis modulation are lacking. METHODS:We profiled expession of 245...

journal_title：BMC cancer

authors： Pentheroudakis G,Kotoula V,Fountzilas E,Kouvatseas G,Basdanis G,Xanthakis I,Makatsoris T,Charalambous E,Papamichael D,Samantas E,Papakostas P,Bafaloukos D,Razis E,Christodoulou C,Varthalitis I,Pavlidis N,Fountzilas G

更新日期：2014-02-20 00:00:00

abstract：BACKGROUND:Most currently known breast cancer predisposition genes play a role in DNA repair by homologous recombination. Recent studies conducted on RAD51 paralogs, involved in the same DNA repair pathway, have identified rare germline mutations conferring breast and/or ovarian cancer predisposition in the RAD51C, RAD...

journal_title：BMC cancer

authors： Golmard L,Caux-Moncoutier V,Davy G,Al Ageeli E,Poirot B,Tirapo C,Michaux D,Barbaroux C,d'Enghien CD,Nicolas A,Castéra L,Sastre-Garau X,Stern MH,Houdayer C,Stoppa-Lyonnet D

更新日期：2013-10-19 00:00:00

abstract：BACKGROUND:Nasopharyngeal carcinoma (NPC) is a type of neoplasm that is highly prevalent in East Asia and Africa with Epstein-Barr virus (EBV), genetic, and dietary factors implicated as possible aetiologic factors. Previous studies suggested the association of certain cytokines with the invasion and metastatic propert...

journal_title：BMC cancer

authors： Chew MM,Gan SY,Khoo AS,Tan EL

更新日期：2010-10-22 00:00:00

abstract：BACKGROUND:Outpatient autologous stem cell transplantations (ASCTs) in multiple myeloma and lymphoma patients have been shown to reduce the overall costs and improve the quality of life relative to inpatient ASCTs. This systematic review and meta-analysis was performed with the aim of comprehensively comparing the risk...

journal_title：BMC cancer

authors： Owattanapanich W,Suphadirekkul K,Kunacheewa C,Ungprasert P,Prayongratana K

更新日期：2018-11-16 00:00:00

abstract：BACKGROUND:The feasibility of submandibular gland (SMG) preservation in oral squamous cell carcinoma (SCC) has occasionally been analyzed, but the differences in survival associated with the presence or absence of SMG preservation remain unknown. We aimed to prospectively evaluate the oncologic results of SMG preservat...

journal_title：BMC cancer

authors： Gu B,Fang Q,Wu Y,Du W,Zhang X,Chen D

更新日期：2020-10-27 00:00:00

abstract：BACKGROUND:Aberrant expression and activation of the IGF-IR have been reported in a variety of human cancers and have been associated with resistance to HER targeted therapy. In this study, we investigated the effect of simultaneous targeting of IGF-IR and HER (erbB) family, with NVP-AEW541 and afatinib, on proliferati...

journal_title：BMC cancer

authors： Ioannou N,Seddon AM,Dalgleish A,Mackintosh D,Modjtahedi H

更新日期：2013-01-31 00:00:00

abstract：BACKGROUND:The prognostic value of rectal invasion is still unclear in stage IVA cervical cancer. The objective of this study is to evaluate patient outcome and prognostic factors in stage IVA cervical cancer treated with radiation therapy. METHODS:A retrospective review of the medical records of patients treated with...

journal_title：BMC cancer

authors： Wakatsuki M,Kato S,Kiyohara H,Ohno T,Karasawa K,Tamaki T,Ando K,Shiba S,Kamada T,Nakano T

更新日期：2016-03-23 00:00:00

abstract：BACKGROUND:The impact of local tumor ablative therapy in oligometastasized prostate cancer (PC) is still under debate. To gain data for this approach, we evaluated oligometastasized PC patients receiving stereotactic body radiotherapy (SBRT) to bone metastases. METHODS:In this retrospective study, 15 oligometastasized...

journal_title：BMC cancer

authors： Habl G,Straube C,Schiller K,Duma MN,Oechsner M,Kessel KA,Eiber M,Schwaiger M,Kübler H,Gschwend JE,Combs SE

更新日期：2017-05-22 00:00:00

abstract：BACKGROUND:Bladder cancer is the ninth most common type of cancer worldwide. In the past, radical cystectomy via open surgery has been considered the gold-standard treatment for muscle invasive bladder cancer. However, in recent years there has been a progressive increase in the use of robot-assisted laparoscopic radic...

journal_title：BMC cancer

authors： Porreca A,Palmer K,Artibani W,Antonelli A,Bianchi L,Brunocilla E,Bocciardi AM,Brausi M,Busetto GM,Carini M,Carrieri G,Celia A,Cindolo L,Cochetti G,Colombo R,De Berardinis E,De Cobelli O,Di Maida F,Ercolino A,Gaboard

更新日期：2021-01-11 00:00:00

abstract：BACKGROUND:It is well known that osteopontin (OPN) plays an important role in tumor progression and that a high OPN expression level in several tumor entities correlates with poor prognosis in cancer patients. However, little is known about the prognostic relevance of the OPN mRNA splice variants. METHODS:We analyzed ...

journal_title：BMC cancer

authors： Hahnel A,Wichmann H,Greither T,Kappler M,Würl P,Kotzsch M,Taubert H,Vordermark D,Bache M

更新日期：2012-04-02 00:00:00

abstract：BACKGROUND:Although this effect is well known, tailored treatment methods have not yet been broadly adopted. The aim of this study was to identify those patient characteristics that most influence the impairment of quality of life and thus to identify those patients who need and can benefit most from specific intervent...

journal_title：BMC cancer

authors： Peters E,Mendoza Schulz L,Reuss-Borst M

更新日期：2016-10-10 00:00:00

abstract：BACKGROUND:We evaluated the hierarchical risk groups for the estimated survival of WHO grade III glioma patients using recursive partitioning analysis (RPA). To our knowledge, this is the first study to address the results of RPA specifically for WHO grade III gliomas. METHODS:A total of 133 patients with anaplastic a...

journal_title：BMC cancer

authors： Park CK,Lee SH,Han JH,Kim CY,Kim DW,Paek SH,Kim DG,Heo DS,Kim IH,Jung HW

更新日期：2009-12-18 00:00:00

abstract：BACKGROUND:Territorial differences in the access to innovative anticancer drugs have been reported from many countries. The objectives of this study were to evaluate access to innovative treatments for metastatic lung cancer in France, and to assess whether socioeconomic indicators were predictors of access at the leve...

journal_title：BMC cancer

authors： Scherpereel A,Durand-Zaleski I,Cotté FE,Fernandes J,Debieuvre D,Blein C,Gaudin AF,Tournier C,Vainchtock A,Chauvin P,Souquet PJ,Westeel V,Chouaïd C

更新日期：2018-10-22 00:00:00

abstract：BACKGROUND:Splenic marginal zone lymphoma (SMZL) is a rare lymphoid B-cell malignant neoplasm with primary involvement of the spleen. It is a chronic disease, of indolent behavior and prolonged survival. However, 25% of cases have higher biological aggressiveness, propensity for histological transformation to high grad...

journal_title：BMC cancer

authors： de Pádua Covas Lage LA,Dos Santos FFC,Levy D,Moreira FR,Couto SCF,Culler HF,de Oliveira Costa R,Rocha V,Pereira J

更新日期：2020-08-03 00:00:00

abstract：BACKGROUND:Several studies show that the regulatory impact of microRNAs (miRNAs) is an essential contribution to the pathogenesis of colorectal cancer (CRC). The expression levels of diverse miRNAs are associated with specific clinical diagnoses and prognoses of CRC. However, this association reveals very little action...

journal_title：BMC cancer

authors： Li J,Mansmann UR

更新日期：2015-06-18 00:00:00

abstract：BACKGROUND:Neoadjuvant chemotherapy (NAC) is a standard treatment for stage II/III breast cancer patients, and response to NAC is a useful prognostic marker. Since its introduction, 6-8 cycles of NAC has become the standard regimen to improve the outcome of these patients. The purpose of this study is to evaluate the p...

journal_title：BMC cancer

authors： Yang Y,Im SA,Keam B,Lee KH,Kim TY,Suh KJ,Ryu HS,Moon HG,Han SW,Oh DY,Han W,Kim TY,Park IA,Noh DY

更新日期：2016-07-21 00:00:00

abstract：BACKGROUND:Microarray gene-profiling of invasive breast cancer has identified different subtypes including luminal A, luminal B, HER2-overexpressing and basal-like groups. Basal-like invasive breast cancer is associated with a worse prognosis. However, the prognosis of basal-like ductal carcinoma in situ (DCIS) is stil...

journal_title：BMC cancer

authors： Zhou W,Jirström K,Johansson C,Amini RM,Blomqvist C,Agbaje O,Wärnberg F

更新日期：2010-11-30 00:00:00

abstract：BACKGROUND:Spinal bone metastases are commonly diagnosed in cancer patients. The consequences are pain both at rest and under exercise, impairment of activities of daily life (ADL), reduced clinical performance, the risk of pathological fractures, and neurological deficits. The aim of this randomized, controlled pilot ...

journal_title：BMC cancer

authors： Rief H,Omlor G,Akbar M,Welzel T,Bruckner T,Rieken S,Haefner MF,Schlampp I,Gioules A,Habermehl D,von Nettelbladt F,Debus J

更新日期：2014-02-05 00:00:00

abstract：BACKGROUND:Allelic counterparts of biallelically expressed genes display an epigenetic symmetry normally manifested by synchronous replication, different from genes subjected to monoallelic expression, which normally are characterized by an asynchronous mode of replication (well exemplified by the SNRPN imprinted locus...

journal_title：BMC cancer

authors： Dotan ZA,Dotan A,Ramon J,Avivi L

更新日期：2008-12-25 00:00:00

abstract：:Following publication of the original article [1], the authors reported that during the production process, Table 1 was omitted. ...

journal_title：BMC cancer

authors： Boon SS,Chen Z,Li J,Lee KYC,Cai L,Zhong R,Chan PKS

更新日期：2019-12-29 00:00:00

abstract：BACKGROUND:The management of unresectable or metastatic gastrointestinal stromal tumors (GISTs) has previously been difficult as they are resistant to conventional chemotherapy and radiation. The development of imatinib mesylate has made a major impact on the management of advanced GISTs. It is apparent that there are ...

journal_title：BMC cancer

authors： Hughes B,Yip D,Goldstein D,Waring P,Beshay V,Chong G

更新日期：2004-10-09 00:00:00

abstract：BACKGROUND:In Europe, gastric cancer remains diagnosed at advanced stage (serosal and/or lymph node involvement). Despite curative management combining perioperative systemic chemotherapy and gastrectomy with D1-D2 lymph node dissection, 5-year survival rates of T3 and/or N + patients remain under 30%. More than 50% of...

journal_title：BMC cancer

authors： Glehen O,Passot G,Villeneuve L,Vaudoyer D,Bin-Dorel S,Boschetti G,Piaton E,Garofalo A

更新日期：2014-03-14 00:00:00

abstract：BACKGROUND:For the expanding population of bladder cancer survivors in Korea, the development of subsequent cancers is a significant concern. Here, we provide the second primary cancer incidence rates and types in Korean patients with bladder cancer. METHODS:Using population-based data from the Korea Central Cancer Re...

journal_title：BMC cancer

authors： Kwon WA,Joung JY,Lim J,Oh CM,Jung KW,Kim SH,Seo HK,Park WS,Chung J,Lee KH,Won YJ

更新日期：2018-05-31 00:00:00

abstract：BACKGROUND:Response-guided neoadjuvant chemotherapy (RG-NACT) with magnetic resonance imaging (MRI) is effective in treating oestrogen receptor positive/human epidermal growth factor receptor-2 negative (ER-positive/HER2-negative) breast cancer. We estimated the expected cost-effectiveness and resources required for it...

journal_title：BMC cancer

authors： Miquel-Cases A,Steuten LM,Rigter LS,van Harten WH

更新日期：2016-09-05 00:00:00

abstract：BACKGROUND:Lactic acid bacteria (LAB) are beneficial probiotic organisms that contribute to improved nutrition, microbial balance, and immuno-enhancement of the intestinal tract, as well as anti-tumor activity. The aim of the present work was to study the growth inhibition of tumor cells by butanol extract of Bifidobac...

journal_title：BMC cancer

authors： Lee DK,Jang S,Kim MJ,Kim JH,Chung MJ,Kim KJ,Ha NJ

更新日期：2008-10-27 00:00:00

abstract：BACKGROUND:Head and neck squamous cell carcinoma (HNSCC) is the sixth leading cause of cancer death in the US. The protein kinase D (PKD) family has emerged as a promising target for cancer therapy with PKD1 being most intensively studied; however, its role in HNSCC has not been investigated. METHODS:The expression of...

journal_title：BMC cancer

authors： Zhang L,Li Z,Liu Y,Xu S,Tandon M,Appelboom B,LaValle CR,Chiosea SI,Wang L,Sen M,Lui VWY,Grandis JR,Wang QJ

更新日期：2018-11-12 00:00:00

abstract：BACKGROUND:Genomic alterations of the proto-oncogene c-erbB-2 (HER-2/neu) are associated with aggressive behavior and poor prognosis in patients with breast cancer. The variable clinical outcomes seen in patients with similar HER2 status, given similar treatments, suggests that the effects of amplification of HER2 can ...

journal_title：BMC cancer

authors： Ellsworth RE,Ellsworth DL,Patney HL,Deyarmin B,Love B,Hooke JA,Shriver CD

更新日期：2008-10-14 00:00:00

abstract：BACKGROUND:Free flap-mediated gene therapy in the tumor bed following surgical resection is a promising approach in cancer targeted treatment of residual disease. We investigated the selective killing efficacy of a lentivirus-mediated cytosine deaminase-thymidine kinase (CDglyTK) gene in transplanted breast cancer deli...

journal_title：BMC cancer

authors： Zhang J,Liu Y,Zang M,Zhu S,Chen B,Li S,Xue B,Yan L

更新日期：2019-09-14 00:00:00