The my experience of taking medicines (MYMEDS) questionnaire for assessing medicines adherence barriers in post-myocardial infarction patients: development and utility.

Abstract:

BACKGROUND:The 'My Experience of Taking Medicines' (MYMEDS) questionnaire is a self-reporting tool for identifying modifiable adherence barriers among individuals prescribed post-myocardial infarction (MI) secondary prevention medicines (SPM) in clinical practice. It was found to be a useful tool to support the conduction of patient-centred consultation in cardiology outpatient leading to improved outcomes including better adherence to SPM and patient satisfaction. This study describes the rationale and development of the MYMEDS tool, its performance and usefulness in identifying modifiable barriers to adherence in cardiology medical practice including user feedback of 204 consecutive post-MI patients who completed an evaluation based on MYMEDS. METHODS:Modifiable non-adherence factors were initially identified based on literature review and stakeholder feedback. A draft MYMEDS questionnaire was piloted in 10 patients and adapted accordingly. The final version comprises six sections, covering current medicines, understanding and satisfaction with medicines, concerns about medicines, practical adherence barriers, fitting medicines into daily routine, and adherence to individual SPMs. The questionnaire was mailed to post-MI patients who then attended an outpatient medicines optimisation clinic. RESULTS:Mean age was 70.5 years and 67.6% were male. The tool was effective in revealing modifiable adherence barriers that could be addressed during the consultation. There were high rates of concern that SPMs could be harmful (33.2%) or overprescribed (43.2%), practical issues with swallowing medicines (8.2%), opening packaging (7.3%) or accessing repeat prescriptions (5.2%), forgetfulness (19.7%), and concerns about inconvenience (13.5%). Mean number of barriers per patient was 1.8 ± 1.5. The medications most commonly associated with non-adherence were statins (21.5%), angiotensin II receptor blockers (21.1%), and antiplatelet agents (18.5%). In total, 42.5% of patients acknowledged non-adherence behaviour. Patient feedback on MYMEDS was positive, with near-unanimous agreement that it was simple, clear and not too long, and that it enabled them to raise any concerns they had about their medicines. Patients reported that their individual medicines related needs were better addressed. CONCLUSIONS:MYMEDS is a practical tool that can successfully identify modifiable barriers to SPM adherence which can be addressed in a clinical setting. It can be easily rolled out in daily clinical practice to enable individualised person-centred medicines optimisation consultation.

journal_name

BMC Cardiovasc Disord

authors

Khatib R,Patel N,Hall AS

doi

10.1186/s12872-020-01362-y

subject

Has Abstract

pub_date

2020-02-03 00:00:00

pages

46

issue

1

issn

1471-2261

pii

10.1186/s12872-020-01362-y

journal_volume

20

pub_type

杂志文章
  • Deletion of the NR4A nuclear receptor NOR1 in hematopoietic stem cells reduces inflammation but not abdominal aortic aneurysm formation.

    abstract:BACKGROUND:The NR4A3 orphan nuclear hormone receptor, NOR1, functions as a constitutively active transcription factor to regulate inflammation, proliferation, and cell survival during pathological vascular remodeling. Inflammatory processes represent key mechanisms leading to abdominal aortic aneurysm (AAA) formation. ...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-017-0701-4

    authors: Qing H,Jones KL,Heywood EB,Lu H,Daugherty A,Bruemmer D

    更新日期:2017-10-18 00:00:00

  • Evaluation of the autonomic nervous system by analysis of heart rate variability in the preterm infants.

    abstract:BACKGROUND:Premature infants may present with damage to the autonomic nervous system (ANS), which may be related to poorer neurological development. Among the techniques used to evaluate the ANS, heart rate variability (HRV) emerged as a simple, non-invasive, and easy to apply tool. The aim of the present study was to ...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-019-1166-4

    authors: de Souza Filho LFM,de Oliveira JCM,Ribeiro MKA,Moura MC,Fernandes ND,de Sousa RD,Pedrino GR,Rebelo ACS

    更新日期:2019-08-16 00:00:00

  • The impact of renal insufficiency and anaemia on survival in patients with cardiovascular disease: a cohort study.

    abstract:BACKGROUND:The simultaneous occurrence of cardiovascular disease (CVD), kidney disease, and anaemia is associated with increased morbidity and mortality. In the community setting, little data exists about the risk associated with milder levels of anaemia when it is present concurrently with CVD and chronic kidney disea...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-9-51

    authors: Anderson J,Glynn LG,Newell J,Iglesias AA,Reddan D,Murphy AW

    更新日期:2009-11-12 00:00:00

  • Omentin-1 is associated with atrial fibrillation in patients with cardiac valve disease.

    abstract:BACKGROUND:Epicardial adipose tissue (EAT) remodeling and adipocytokines are associated with structural remodeling in atrial fibrillation (AF). However, the role of omentin-1, a novel adipocytokine, in structural remodeling remains unknown. METHODS:Hematoxylin and eosin (H&E) and Masson's trichrome stains were used to...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-020-01478-1

    authors: Chen Y,Liu F,Han F,Lv L,Tang CE,Xie Z,Luo F

    更新日期:2020-05-06 00:00:00

  • Assessment of central haemomodynamics from a brachial cuff in a community setting.

    abstract:BACKGROUND:Large artery stiffening and wave reflections are independent predictors of adverse events. To date, their assessment has been limited to specialised techniques and settings. A new, more practical method allowing assessment of central blood pressure from waveforms recorded using a conventional automated oscil...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-12-48

    authors: Nunan D,Wassertheurer S,Lasserson D,Hametner B,Fleming S,Ward A,Heneghan C

    更新日期:2012-06-26 00:00:00

  • Life's simple 7 and cardiovascular disease risk knowledge in Hong Kong.

    abstract:BACKGROUND:This study aimed at investigating the CV health and CV disease knowledge in terms of LS7 score among 3 age groups in Hong Kong. METHODS:A cross-sectional multicenter observational study was conducted to observe the CV health and disease risk knowledge in Hong Kong. Elderly subjects were recruited from 15 el...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12872-019-1171-7

    authors: Lee VWY,Fong FYH,Cheng FWT,Yan BPY

    更新日期:2019-08-02 00:00:00

  • Heart disease and left ventricular rotation - a systematic review and quantitative summary.

    abstract:BACKGROUND:Left ventricular (LV) rotation is increasingly examined in those with heart disease. The available evidence measuring LV rotation in those with heart diseases has not been systematically reviewed. METHODS:To review systematically the evidence measuring LV rotational changes in various heart diseases compare...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,评审

    doi:10.1186/1471-2261-12-46

    authors: Phillips AA,Cote AT,Bredin SS,Warburton DE

    更新日期:2012-06-24 00:00:00

  • Takotsubo cardiomyopathy in a patient with ileus: a case report.

    abstract:BACKGROUND:Takotsubo cardiomyopathy (TCM) is a form of stress-induced cardiomyopathy featured by the dilatation of the apex of the left ventricle during systole. Whereas the pathogenesis of this disorder is not well understood, it usually occurs after an emotional or physical stress such as acute asthma, surgery, chemo...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-017-0700-5

    authors: Guo CC,Chou NS

    更新日期:2017-10-17 00:00:00

  • BRG1 overexpression in smooth muscle cells promotes the development of thoracic aortic dissection.

    abstract:BACKGROUND:Here we investigated Brahma-related gene 1 (BRG1) expression in aortic smooth muscle cells (SMCs) and its role in the regulation of the pathological changes in aortic SMCs of thoracic arotic dissection (TAD). METHODS:BRG1, matrix metalloproteinase 2 (MMP2), and MMP9 mRNA and protein expression in human aort...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-14-144

    authors: Yuan Y,Wang C,Xu J,Tao J,Xu Z,Huang S

    更新日期:2014-10-11 00:00:00

  • A medical epopee: recurrent fungal endocarditis, heart transplantation and chylopericardium.

    abstract:BACKGROUND:Candida prosthetic endocarditis is associated with high mortality rates and valve replacement surgery, together with antifungal treatment, play a major role in eradicating the fungal infection. Valve reoperations in these scenarios may be relatively common due to the high infection relapse rates and, in some...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-020-01755-z

    authors: de Santis A,Gilberto GM,Mangini S,Megale AB,Gaiotto FA,Terra RM,Garcia RG

    更新日期:2020-10-31 00:00:00

  • Value of the Barthel scale in prognostic prediction for patients with cerebral infarction.

    abstract:BACKGROUND:This study aims to evaluate the ADL(activity of daily living) of patients with acute cerebral infarction through BI scoring, in order to observe its predictive value in the prognosis of these patients. METHODS:According to the inclusion and exclusion criteria, patients with acute anterior circulation cerebr...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-019-01306-1

    authors: Li QX,Zhao XJ,Wang Y,Wang DL,Zhang J,Liu TJ,Peng YB,Fan HY,Zheng FX

    更新日期:2020-01-13 00:00:00

  • A potential marker of bare metal stent restenosis: monocyte count - to- HDL cholesterol ratio.

    abstract:BACKGROUND:Oxidation and inflammation play significant roles in the pathogenesis of coronary artery diseases. Monocyte count to high-density lipoprotein (HDL) cholesterol ratio (MHR) is a new marker and has revealed as an indicator of inflammation in the literature. The present study aimed to search the effect of MHR o...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-016-0367-3

    authors: Ucar FM

    更新日期:2016-10-03 00:00:00

  • The role of a behavioural medicine intervention in physiotherapy for the effects of rehabilitation outcomes in exercise-based cardiac rehabilitation (ECRA) - the study protocol of a randomised, controlled trial.

    abstract:BACKGROUND:To help patients with coronary artery disease (CAD) benefit from the positive health effects attained by exercise-based cardiac rehabilitation (CR), adherence to these programmes according to international guidelines is important. Strategies to increase adherence to exercise-based CR are mainly an unexplored...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12872-017-0557-7

    authors: Borg S,Öberg B,Nilsson L,Söderlund A,Bäck M

    更新日期:2017-05-25 00:00:00

  • Atherosclerosis profile and incidence of cardiovascular events: a population-based survey.

    abstract:BACKGROUND:Atherosclerosis is a chronic progressive disease often presenting as clinical cardiovascular disease (CVD) events. This study evaluated the characteristics of individuals with a diagnosis of atherosclerosis and estimated the incidence of CVD events to assist in the early identification of high-risk individua...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-9-46

    authors: Robinson JG,Fox KM,Bullano MF,Grandy S,SHIELD Study Group.

    更新日期:2009-09-15 00:00:00

  • Permanent pacemaker implanted into patient's left ventricle via subclavian artery by mistake: a case report.

    abstract:BACKGROUND:Although various iatrogenic complications could be observed in the process of permanent pacemaker implantation, pacemaker electrode mistakenly implanted into left ventricle via subclavian artery and aortic valve has not been reported. CASE PRESENTATION:Herein, we reported a 71-year-old woman with permanent ...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-015-0032-2

    authors: Tang G,Zhai C,Wang Z,Chen H

    更新日期:2015-05-12 00:00:00

  • Evaluation of β-blocker therapy for long-term outcomes in patients with low ejection fraction after cardiac surgery.

    abstract:BACKGROUND:Preoperative low left ventricular ejection fraction (LVEF) has been reported as an independent risk factor for in-hospital mortality. However, there were few studies evaluating the long-term mortality in these patients. We, therefore, conducted this study to investigate long-term outcomes of surgery on patie...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-020-01651-6

    authors: Fan FD,Zhang HT,Pan T,Tang XL,Wang DJ

    更新日期:2020-08-20 00:00:00

  • Effects of abciximab on key pattern of human coronary restenosis in vitro: impact of the SI/MPL-ratio.

    abstract:BACKGROUND:The significant reduction of angiographic restenosis rates in the ISAR-SWEET study (intracoronary stenting and antithrombotic regimen: is abciximab a superior way to eliminate elevated thrombotic risk in diabetes) raises the question of whether abciximab acts on clopidogrel-independent mechanisms in suppress...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-6-14

    authors: Voisard R,Alan M,von Müller L,Baur R,Hombach V

    更新日期:2006-04-04 00:00:00

  • Isolated metastasis of hepatocellular carcinoma in the right ventricle.

    abstract:BACKGROUND:Hepatocellular carcinoma (HCC) with right ventricle metastasis without inferior vena cava and right atrium involvement is very rare and the prognosis of HCC with RV metastasis is generally poor. The mass in the cardiac chamber may lead to lethal instability of hemodynamics, however, the initial symptom is pr...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,评审

    doi:10.1186/s12872-019-01290-6

    authors: Zhang XT,Li Y,Ren SH,Ren WD,Song G,Xiao YJ,Sun FF,Sun L,Yang XH,Tan XY

    更新日期:2019-12-12 00:00:00

  • Differing effects of beta-blockers on long-term clinical outcomes following percutaneous coronary intervention between patients with mid-range and reduced left ventricular ejection fraction.

    abstract:BACKGROUND:The aim of this study was to determine the difference in effects of beta-blockers on long-term clinical outcomes between ischemic heart disease (IHD) patients with mid-range ejection fraction (mrEF) and those with reduced ejection fraction (rEF). METHODS:Data were assessed of 3508 consecutive IHD patients w...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-021-01850-9

    authors: Shitara J,Naito R,Kasai T,Endo H,Wada H,Doi S,Konishi H,Tsuboi S,Ogita M,Dohi T,Okazaki S,Miyauchi K,Daida H

    更新日期:2021-01-15 00:00:00

  • Prognosis after percutaneous coronary intervention in patients with psoriasis: a cohort study using Danish nationwide registries.

    abstract:BACKGROUND:Psoriasis is an inflammatory disease associated with increased risk of coronary artery disease. However, the potential impact of psoriasis on the prognosis following percutaneous coronary revascularization (PCI) is unknown. METHODS:The study comprised the entire Danish population undergoing first-time PCI i...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-12-79

    authors: Ahlehoff O,Lindhardsen J,Gislason GH,Olesen JB,Charlot M,Skov L,Torp-Pedersen C,Hansen PR

    更新日期:2012-09-24 00:00:00

  • Adipo/cytokines in atherosclerotic secretomes: increased visfatin levels in unstable carotid plaque.

    abstract:BACKGROUND:Novel pro-inflammatory and anti-inflammatory derivatives from adipose tissue, known as adipokines, act as metabolic factors. The aim of this study was to analyse the secreted expression of different adipo/cytokines in secretomes of unstable carotid atherosclerotic plaque versus non-atherosclerotic mammary ar...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-016-0320-5

    authors: Auguet T,Aragonès G,Guiu-Jurado E,Berlanga A,Curriu M,Martinez S,Alibalic A,Aguilar C,Camara ML,Hernández E,Ruyra X,Martín-Paredero V,Richart C

    更新日期:2016-07-08 00:00:00

  • Quality of life after aortic valve repair is similar to Ross patients and superior to mechanical valve replacement: a cross-sectional study.

    abstract:BACKGROUND:In patients after aortic valve surgery, the quality of life is hypothesized to be influenced by the type of the valve procedure. A cross-sectional study on the postoperative quality of life was carried out in patients after aortic valve-sparing surgery (with regards to the age of the patient), Ross procedure...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-016-0236-0

    authors: Zacek P,Holubec T,Vobornik M,Dominik J,Takkenberg J,Harrer J,Vojacek J

    更新日期:2016-04-02 00:00:00

  • Implication of plasma intermedin levels in patients who underwent first-time diagnostic coronary angiography: a single centre, cross-sectional study.

    abstract:BACKGROUND:Intermedin (IMD) is involved in the prevention of atherosclerotic plaque progression, possessing cardioprotective effects from hypertrophy, fibrosis and ischemia-reperfusion injury. Elevated plasma IMD levels have been demonstrated in patients with acute coronary syndromes. No human study has examined the ro...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-14-182

    authors: Yamac AH,Bacaksiz A,Ismailoglu Z,Kucukbuzcu S,Sevgili E,Asoglu E,Nasifov M,Jafarov P,Erdogan E,Goktekin O

    更新日期:2014-12-11 00:00:00

  • Approach selection of radiofrequency catheter ablation for ventricular arrhythmias originating from the left ventricular summit: potential relevance of Pseudo Delta wave, Intrinsicoid deflection time, maximal deflection index.

    abstract:BACKGROUND:Ventricular arrhythmias (VAs) originating from the left ventricular summit is a challenge for radiofrequency catheter ablation (RFCA). The present study aimed to investigate the appropriate RFCA strategy for VAs originating from the left ventricular summit. METHODS:Forty-five consecutive patients with VAs a...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-017-0575-5

    authors: Zheng C,Li J,Li J,Zhou DP,Li XW,Wu SJ,Lin JF

    更新日期:2017-05-30 00:00:00

  • INvestigation on Routine Follow-up in CONgestive HearT FAilure Patients with Remotely Monitored Implanted Cardioverter Defibrillators SysTems (InContact).

    abstract:BACKGROUND:In heart failure (HF) patients with implantable cardioverter defibrillators (ICD) or cardiac resynchronisation therapy defibrillators (CRT-D), remote monitoring has been shown to result in at least non-inferior outcomes relative to in-clinic visits. We aimed to provide further evidence for this effect, and t...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1186/s12872-018-0864-7

    authors: Hansen C,Loges C,Seidl K,Eberhardt F,Tröster H,Petrov K,Grönefeld G,Bramlage P,Birkenhauer F,Weiss C

    更新日期:2018-06-28 00:00:00

  • A-002 (Varespladib), a phospholipase A2 inhibitor, reduces atherosclerosis in guinea pigs.

    abstract:BACKGROUND:The association of elevated serum levels of secretory phospholipase A2 (sPLA2) in patients with cardiovascular disease and their presence in atherosclerotic lesions suggest the participation of sPLA2 enzymes in this disease. The presence of more advanced atherosclerotic lesions in mice that overexpress sPLA2...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-9-7

    authors: Leite JO,Vaishnav U,Puglisi M,Fraser H,Trias J,Fernandez ML

    更新日期:2009-02-17 00:00:00

  • Early changes in ambulatory electrocardiography after transcatheter closure in patients with atrial septal defect and factors affecting heart rate variability.

    abstract:BACKGROUND:Factors affecting heart rate variability (HRV) in patients with atrial septal defect (ASD) have not been clarified. This study sought to identify those factors and establish a preliminary risk model. METHODS:A total of 154 patients with ASD who underwent transcatheter closure and met the study requirements ...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-020-01699-4

    authors: Su Z,Cao Q,Zhang H,Sun W,Zhang H,Sheng Y,Yang R,Kong X

    更新日期:2020-09-11 00:00:00

  • Association between markers of glycemia and carotid intima-media thickness: the MARK study.

    abstract:BACKGROUND:Carotid intima-media thickness (C-IMT) is a reliable predictor of cardiovascular events. We Investigated the relationship between markers of glycemia and C-IMT in intermediate-risk cardiovascular patients. METHODS:This study analyzed 427 subjects, aged 35 to 74 years (mean, 60.3 ± 8.5 years), 55 % women, en...

    journal_title:BMC cardiovascular disorders

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1186/s12872-016-0380-6

    authors: Gomez-Marcos MA,Gomez-Sanchez L,Patino-Alonso MC,Recio-Rodriguez JI,Regalado NG,Ramos R,Marti R,Agudo-Conde C,Rodriguez-Sanchez E,Maderuelo-Fernandez JA,Garcia-Ortiz L,MARK Group.

    更新日期:2016-10-28 00:00:00

  • Administration of granulocyte-colony stimulating factor accompanied with a balanced diet improves cardiac function alterations induced by high fat diet in mice.

    abstract:BACKGROUND/OBJECTIVES:High fat diet (HFD) is a major contributor to the development of obesity and cardiovascular diseases due to the induction of cardiac structural and hemodynamic abnormalities. We used a model of diabetic cardiomyopathy in C57Bl/6 mice fed with a HFD to investigate the effects of granulocyte-colony ...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-015-0154-6

    authors: Daltro PS,Alves PS,Castro MF,Azevedo CM,Vasconcelos JF,Allahdadi KJ,de Freitas LA,de Freitas Souza BS,Dos Santos RR,Soares MB,Macambira SG

    更新日期:2015-12-03 00:00:00

  • The association between T wave inversion in leads with ST-elevation and patency of the infarct-related artery.

    abstract:BACKGROUND:Up to over half of the patients with ST-segment elevation myocardial infarction (STEMI) are reported to undergo spontaneous reperfusion without therapeutic interventions. Our objective was to evaluate the applicability of T wave inversion in electrocardiography (ECG) of patients with STEMI as an indicator of...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-021-01851-8

    authors: Ranjbar A,Sohrabi B,Sadat-Ebrahimi SR,Ghaffari S,Kazemi B,Aslanabadi N,Seyvani B,Hajizadeh R

    更新日期:2021-01-12 00:00:00