Abstract:
BACKGROUND:Breast cancer survivors have an elevated risk of cognitive impairment compared to age-matched women without cancer. Causes of this impairment are complex, including both treatment and psychological factors. Mindfulness-based interventions, which have been shown to improve cognitive function in the general population, may be one approach to mitigate cognitive impairment in this survivor population. Our objective was to conduct a systematic literature review of studies on the effect of mindfulness-based interventions on cognition among breast cancer survivors. METHODS:We conducted searches of three electronic databases (Scopus, PubMed and Cochrane Database of Systematic Reviews) in September 2017 for studies pertaining mindfulness and cognitive function among breast cancer survivors. Abstracts were manually searched by two reviewers and additional articles were identified through reference lists. RESULTS:A total of 226 articles were identified through our systematic search and six met inclusion criteria for this review. The reviewed studies lacked consistency in terms of the cognition domains studied (e.g. executive function, recent memory, etc) and in the measures used to assess cognition. Of the included studies, two found no association between mindfulness interventions and cognitive function, two found improvement that was not sustained at the follow-up, and another two found sustained improvement at 2- or 6-months. CONCLUSIONS:Mindfulness-based interventions have shown some evidence for improving cognition among breast cancer survivors, but further research using validated and comprehensive cognitive assessments is needed. More research is also needed related to the timing, duration and content of mindfulness interventions.
journal_name
BMC Cancerjournal_title
BMC cancerauthors
Cifu G,Power MC,Shomstein S,Arem Hdoi
10.1186/s12885-018-5065-3subject
Has Abstractpub_date
2018-11-26 00:00:00pages
1163issue
1issn
1471-2407pii
10.1186/s12885-018-5065-3journal_volume
18pub_type
杂志文章相关文献
BMC CANCER文献大全abstract:BACKGROUND:pressurized intraperitoneal aerosol chemotherapy (PIPAC), with or without electrostatic precipitation (ePIPAC), was recently introduced in the treatment of peritoneal metastases (PM) from ovarian cancer (OC). Preliminary clinical data are promising, but several methodological issues as well the anticancer ef...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-019-5658-5
更新日期:2019-05-07 00:00:00
abstract:BACKGROUND:Clinical characterization of bladder carcinomas is still inadequate using the standard clinico-pathological prognostic markers. We assessed the correlation between nm23-H1, Rb, EGFR and p53 in relation to the clinical outcome of patients with muscle invasive bilharzial bladder cancer (MI-BBC). METHODS:nm23-...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-9-32
更新日期:2009-01-26 00:00:00
abstract:BACKGROUND:Methotrexate-associated lymphoproliferative disorder (MTX-LPD) is a benign lymphoid proliferation or malignant lymphoma in patients who have been treated with MTX. MTX withdrawal and observation for a short period should be considered in the initial management of patients who develop LPD while on MTX therapy...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-016-2672-8
更新日期:2016-08-15 00:00:00
abstract:BACKGROUND:A low cost and accurate method for detecting high-risk (HR) human papillomavirus (HPV) is important to permit HPV testing for cervical cancer prevention. We used a commercially available HPV method (H13, Hybribio) which was documented to function accurately in a reduced volume of cervical specimen to determi...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-018-4438-y
更新日期:2018-05-15 00:00:00
abstract:BACKGROUND:Most currently known breast cancer predisposition genes play a role in DNA repair by homologous recombination. Recent studies conducted on RAD51 paralogs, involved in the same DNA repair pathway, have identified rare germline mutations conferring breast and/or ovarian cancer predisposition in the RAD51C, RAD...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-13-484
更新日期:2013-10-19 00:00:00
abstract:BACKGROUND:Malignant melanoma is an aggressive type of skin cancer, and despite recent advances in treatment, the survival rate of the metastatic form remains low. Nifuroxazide analogues are drugs based on the substitution of the nitrofuran group by benzofuroxan, in view of the pharmacophore similarity of the nitro gro...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-015-1835-3
更新日期:2015-10-27 00:00:00
abstract:BACKGROUND:Solid tumours are less oxygenated than normal tissues. This is called tumour hypoxia and leads to resistance to radiotherapy and chemotherapy. The molecular mechanisms underlying such resistance have been investigated in a range of tumour types, including the adult brain tumours glioblastoma, yet little is k...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-019-5476-9
更新日期:2019-04-03 00:00:00
abstract:BACKGROUND:The aim of this study was to determine the safety and efficacy of fractionated stereotactic radiotherapy (SRT) in combination with systemic therapies (ST) for brain metastases (BM). METHODS:Ninety-nine patients (171 BM) received SRT and concurrent ST (group 1) and 95 patients (131 BM) received SRT alone wit...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-020-07491-z
更新日期:2020-10-13 00:00:00
abstract:BACKGROUND:Protein secretion by mammary cells results in autocrine and paracrine signaling that defines cell growth, migration and the extracellular environment. Even so, we have a limited understanding of the cellular processes that regulate protein secretion. METHODS:In this study, we utilize human epithelial mammar...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-11-69
更新日期:2011-02-14 00:00:00
abstract:BACKGROUND:Obesity is linked to poor disease outcomes in breast cancer patients. However, this link was mostly based on body weight or BMI rather than body-fat. The purpose of this study was to evaluate the relationship between body-fat gain and disease progression in Taiwanese women after breast cancer surgery and how...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-017-3869-1
更新日期:2017-12-18 00:00:00
abstract:BACKGROUND:Interleukin 12 (IL-12) is a cytokine that has been reported to exhibit potent tumoricidal effects in animal tumor models. A combined approach using Paclitaxel and platinum-based doublet chemotherapy is the most commonly used backbone regimen for treating lung cancer. Despite numerous studies regarding the an...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-016-2701-7
更新日期:2016-08-22 00:00:00
abstract:BACKGROUND:Socioeconomic inequalities in cancer mortality in Britain have been shown to be present in the 1990s and early 2000s. Little is known about on-going patterns in such inequalities in cancer mortality. We examined time trends in socioeconomic inequalities in cancer mortality in Britain between 1978 and 2013. ...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-14-474
更新日期:2014-06-30 00:00:00
abstract:BACKGROUND:Recent data in esophageal cancer suggests the variant allele of a single-nucleotide polymorphism (SNP) in XRCC1 may be associated with resistance to radiochemotherapy. However, this SNP has not been assessed in a histologically homogeneous clinical trial cohort that has been treated with a uniform approach. ...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-11-176
更新日期:2011-05-17 00:00:00
abstract:BACKGROUND:Disparities in multiple myeloma (MM) prognosis based on sociodemographic factors may exist. We investigated whether education level at diagnosis influenced Chinese MM patient outcomes. METHODS:We performed a multicenter retrospective analysis of data from 773 MM patients across 9 centers in China from 2006 ...
journal_title:BMC cancer
pub_type: 杂志文章,多中心研究
doi:10.1186/s12885-020-07178-5
更新日期:2020-08-08 00:00:00
abstract:BACKGROUND:Alteration in gut microbiota has been recently linked with childhood leukemia and the use of chemotherapy. Whether the perturbed microbiota community is restored after disease remission and cessation of cancer treatment has not been evaluated. This study examines the chronological changes of gut microbiota i...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-020-6654-5
更新日期:2020-02-24 00:00:00
abstract:BACKGROUND:The neutrophil-to-lymphocyte ratio (NLR), a simple marker of the systemic inflammatory response in critical care patients, has been suggested as an independent prognostic factor for several solid malignancies. We investigated the utility of pretreatment NLR as a prognosticator in patients who presented with ...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-016-2134-3
更新日期:2016-02-16 00:00:00
abstract:BACKGROUND:Multimodality treatment improves the chance of survival but increases the risk for long-term side effects in young cancer survivors, so-called" Adolescents and Young Adults"(AYAs). Compared to the general population AYAs have a 5 to 15-fold increased risk of cardiovascular morbidity. Thus, improving modifiab...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-016-2896-7
更新日期:2016-11-08 00:00:00
abstract:BACKGROUND:Patients with metastatic renal cell cancer (mRCC) are commonly treated with the tyrosine kinase inhibitor sunitinib, which blocks signalling from vascular endothelial growth factor (VEGF) - and platelet-derived growth factor-receptors, inhibiting development of new blood vessels. There are currently no predi...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-020-06770-z
更新日期:2020-04-22 00:00:00
abstract:BACKGROUND:Currently, there are three main surgical approaches for resectable esophageal cancer: open transthoracic esophagectomy (OTE), conventional minimally invasive esophagectomy (MIE) and robot-assisted esophagectomy (RAE). Previous studies had demonstrated the better short-term outcomes in MIE or RAE when compare...
journal_title:BMC cancer
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/s12885-019-5799-6
更新日期:2019-06-21 00:00:00
abstract:BACKGROUND:Alterations in the redox balance are involved in the origin, promotion and progression of cancer. Inter-individual differences in the oxidative stress regulation can explain a part of the variability in cancer susceptibility.The aim of this study was to evaluate if polymorphisms in genes codifying for the di...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-14-861
更新日期:2014-11-21 00:00:00
abstract:BACKGROUND:Uridine 5'-diphosphate-glucuronosyltransferase 2B (UGT2B) genes code for enzymes that catalyze the clearance of testosterone, dihydrotestosterone (DHT), and DHT metabolites in the prostate basal and luminal tissue. The expression of the UGT2B15, UGT2B17, and UGT2B28 enzymes has not been evaluated in prostate...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-017-3463-6
更新日期:2017-07-03 00:00:00
abstract:BACKGROUND:Kruppel family member zinc binding protein 89 (ZBP-89), also known as ZNF148, regulates Bak expression via binding to GC-rich promoter domain. It is not clear if other GC-rich binding factors, such as Sp family members, can interact with ZBPp-89 on Bak expression. This study aims to elucidate the mechanism o...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-018-4349-y
更新日期:2018-04-13 00:00:00
abstract:BACKGROUND:Hepatocellular carcinoma (HCC) is a lethal disease, while the precise underlying molecular mechanisms of HCC pathogenesis remain to be defined. MicroRNA (miRNA), a class of non-coding small RNAs, can post-transcriptionally regulate gene expression. Altered miRNA expression has been reported in HCCs. This stu...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-016-2801-4
更新日期:2016-10-18 00:00:00
abstract:BACKGROUND:The serine/threonine kinase PIM1 has been implicated as an oncogene in various human cancers including lymphomas, gastric, colorectal and prostate carcinomas. In mouse models, Pim1 is known to cooperate with c-Myc to promote tumorigenicity. However, there has been limited analysis of the tumorigenic potentia...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-10-248
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Associations between polycyclic aromatic hydrocarbons (PAHs) and colorectal cancer have been reported previously but few studies have characterized PAH exposure using biological measurements. We evaluated colorectal cancer risk in relation to urinary concentration of 1-hydroxypyrene glucuronide (1-OHPG), a p...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-13-282
更新日期:2013-06-11 00:00:00
abstract:BACKGROUND:Long-term locoregional control in locally advanced squamous cell carcinoma of the head and neck (SCCHN) remains challenging. While recent years have seen various approaches to improve outcome by intensification of treatment schedules through introduction of novel induction and combination chemotherapy regime...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-11-182
更新日期:2011-05-19 00:00:00
abstract:BACKGROUND:The majority of patients undergoing hepatectomy for hepatocellular carcinoma (HCC) suffer from underlying liver disease and are exposed to the risk of postoperative ascites, which is favored by an imbalance between portal venous inflow and a diminished hepatic volume. Finding a reversible, non-invasive metho...
journal_title:BMC cancer
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/s12885-018-4667-0
更新日期:2018-08-23 00:00:00
abstract:BACKGROUND:Although cisplatin is one of the most effective chemotherapeutic agents, cisplatin alone does not achieve a satisfactory therapeutic outcome. Also cisplatin accumulation shows toxicity to normal tissues. In this study, we examined the possibility of HemoHIM both to enhance anticancer effect with cisplatin an...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-9-85
更新日期:2009-03-17 00:00:00
abstract:BACKGROUND:Cancer cells release exosomes and can be taken up by mast cells (MCs), but the potential functional effects of MCs on tumor metastasis remain unknown. METHOD:Exosomes were isolated from the lung adenocarcinoma cell line A549, and the uptake of PKH26-labeled exosomes by bone marrow MCs was examined via flow ...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/s12885-019-6203-2
更新日期:2019-10-29 00:00:00
abstract:BACKGROUND:Abundant research suggested that the cancer cells avoid destruction by the immune system through down-regulation or mutation of death receptors. Therefore, it is very important that finding the agents that increase the death receptors of cancer cells. In this study, we demonstrated that the snake venom toxin...
journal_title:BMC cancer
pub_type: 杂志文章
doi:10.1186/1471-2407-12-228
更新日期:2012-06-08 00:00:00