Abstract:
:Regular physical activity prescription is a key point for healthy aging and chronic disease management and prevention. Our aim was to evaluate the antioxidant defense system and the mitochondrial status in peripheral blood mononuclear cells (PBMCs) and the level of oxidative damage in plasma in active, intermediate and inactive elderly. In total, 127 healthy men and women >55 years old participated in the study and were classified according on their level of declared physical activity. A more active lifestyle was accompanied by lower weight, fat mass and body mass index when compared to a more sedentary life-style. Active participants exhibited lower circulating PBMCs than inactive peers. Participants who reported higher levels of exercise had increased antioxidant protein levels when compared to more sedentary partakers. Carbonylated protein levels exhibited similar behavior, accompanied by a significant raise in expression of cytochrome c oxidase subunit IV in PBMCs. No significant changes were found in the activities of antioxidant enzymes and in the expression of structural (MitND5) and mitochondrial dynamic-related (PGC1α and Mitofusins1/2.) proteins. Active lifestyle and daily activities exert beneficial effects on body composition and it enhances the antioxidant defenses and oxidative metabolism capabilities in PBMCs from healthy elderly.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Busquets-Cortés C,Capó X,Bibiloni MDM,Martorell M,Ferrer MD,Argelich E,Bouzas C,Carreres S,Tur JA,Pons A,Sureda Adoi
10.3390/nu10101555subject
Has Abstractpub_date
2018-10-20 00:00:00issue
10issn
2072-6643pii
nu10101555journal_volume
10pub_type
杂志文章相关文献
Nutrients文献大全abstract::Vitamin C (ascorbate, ASC) is a critical antioxidant in the body with specific roles in the brain. Despite a recent interest in vitamin C therapies for critical care medicine, little is known about vitamin C regulation during acute inflammation and critical illnesses such as sepsis. Using a cecal slurry (CS) model of ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12040911
更新日期:2020-03-26 00:00:00
abstract::Spinal muscular atrophy (SMA), the main genetic cause of infant death, is a neurodegenerative disease characterized by the selective loss of motor neurons in the anterior horn of the spinal cord, accompanied by muscle wasting. Pathomechanically, SMA is caused by low levels of the survival motor neuron protein (SMN) re...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12123842
更新日期:2020-12-16 00:00:00
abstract::There are a significant number of studies on cognitive restraint among individuals with varying dietary patterns. Although most research has found that vegetarians report higher levels of cognitive restraint compared to non-vegetarians, many studies have contributed inconsistent results. The aim of the current study, ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12072133
更新日期:2020-07-17 00:00:00
abstract::Background: Besides anemia, iron deficiency may cause more subtle symptoms, including the restless legs syndrome (RLS), the chronic fatigue syndrome (CFS) or sleeping disorders. Objective: The aim of this pre-planned secondary analysis of the IronWoMan randomized controlled trial (RCT) was to compare the frequency and...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12051313
更新日期:2020-05-05 00:00:00
abstract:UNLABELLED:Hormonal contraceptives may produce side effects that deter women from their use as a method of family planning. In nutritionally vulnerable populations these effects may be more pronounced due to micronutrient deficiencies and health status. Previous studies have been unable to resolve whether micronutrient...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu6093353
更新日期:2014-08-26 00:00:00
abstract:BACKGROUND:Chronic kidney disease and inflammation promote loss of Klotho expression. Given the well-established anti-inflammatory effects of omega-3 fatty acids, we aimed to investigate the effect of fish oil supplementation in a model of CKD. METHODS:Male C57BL/6 mice received supplementation with an adenine-enriche...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10091283
更新日期:2018-09-11 00:00:00
abstract::Wine grape pomace flour (WGPF) is a fruit byproduct that is high in fiber and antioxidants. We tested whether WGPF consumption could affect blood biochemical parameters, including oxidative stress biomarkers. In a three-month intervention study, 27 male volunteers, each with some components of metabolic syndrome, cons...
journal_title:Nutrients
pub_type: 临床试验,杂志文章
doi:10.3390/nu10101388
更新日期:2018-10-01 00:00:00
abstract::Gynostemma pentaphyllum is widely used in Asia as a herbal medicine to treat type 2 diabetes, dyslipidemia, and inflammation. Here, we investigated the anti-obesity effect and underlying mechanism of G. pentaphyllum extract (GPE) enriched in gypenoside L, gypenoside LI, and ginsenoside Rg3 and obtained using a novel e...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11102475
更新日期:2019-10-15 00:00:00
abstract::Obesity is an escalating health crisis of pandemic proportions and by all accounts it has yet to reach its peak. Growing evidence suggests that obesity may have its origins in utero. Recent studies have shown that maternal obesity during pregnancy may promote adipogenesis in offspring. However, these studies were larg...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11030495
更新日期:2019-02-27 00:00:00
abstract::Patients with irritable bowel syndrome (IBS) exhibit low-grade inflammation and increased gut permeability. Dietary sugar has been shown to contribute to low-grade inflammation and increased gut permeability, and to correlate with gastrointestinal (GI) symptoms. The aim of the present study was to examine the effect o...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11071662
更新日期:2019-07-20 00:00:00
abstract::Dietary record tools such as food frequency questionnaire (FFQ) and food diaries (FD) are the most commonly used choices for assessing dietary intakes in most large-scale epidemiological studies. The authors developed a self-administered 360-item food frequency questionnaire (FFQ) to assess dietary intakes amongst a p...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12020383
更新日期:2020-01-31 00:00:00
abstract::Historically, Mangifera indica L. cultivations have been widely planted in tropical areas of India, Africa, Asia, and Central America. However, at least 20 years ago its spreading allowed the development of some cultivars in Sicily, an island to the south of Italy, where the favourable subtropical climate and adapted ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu9050525
更新日期:2017-05-20 00:00:00
abstract::Reduction in cholesterol blood levels represents one of the therapeutic goals to achieve in order to reduce the occurrence of cardiovascular diseases. Commonly, this goal is attempted by promoting healthy lifestyle behaviors and low-fat diets. Recently, several nutraceuticals have been shown to possess cholesterol-low...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11010163
更新日期:2019-01-14 00:00:00
abstract::Glycyrrhizic acid (GA) ameliorates many components of the metabolic syndrome, but its potential therapeutic use is marred by edema caused by inhibition of renal 11β-hydroxysteroid dehydrogenase 2 (11β-HSD2). We assessed whether 100 mg/kg per day GA administered orally could promote metabolic benefits without causing e...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu6114856
更新日期:2014-11-04 00:00:00
abstract::Despite poverty reduction and increased promotion of improved nutrition practices in the community, undernutrition in Ethiopia remains a concern. The present study aimed to explore the demand and supply side barriers that limit the uptake of nutrition services among pregnant women from the rural communities of the Tig...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10111687
更新日期:2018-11-05 00:00:00
abstract::The loss of skeletal muscle mass with energy deficit is thought to be due to protein breakdown by the autophagy-lysosome and the ubiquitin-proteasome systems. We studied the main signaling pathways through which exercise can attenuate the loss of muscle mass during severe energy deficit (5500 kcal/day). Overweight men...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11112824
更新日期:2019-11-19 00:00:00
abstract::Iron is an essential mineral nutrient for all living organisms, involved in a plurality of biological processes. Its deficit is the cause of the most common form of anemia in the world: iron deficiency anemia (IDA). This paper reviews iron content in various parts of 1228 plant species and its absorption from herbal p...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu7125535
更新日期:2015-12-10 00:00:00
abstract::Oxidative Balance Scores (OBSs) are tools that have emerged to evaluate the global balance of individuals' oxidation-reduction status. The aim was to compare OBSs available in the literature regarding their characteristics and associations with chronic diseases in epidemiological studies. Studies that developed OBSs w...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11040774
更新日期:2019-04-03 00:00:00
abstract::The objective of this study was to examine the relationship between different sleep parameters and energy and macronutrient intake in school-aged children. A total of 203 children 6 to 9 years of age participated in this cross-sectional study. Anthropometric measurements were taken first. Diet was assessed with 3-day ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11112568
更新日期:2019-10-24 00:00:00
abstract::Syndecans are transmembrane proteoglycans that, like integrins, bind to components of the extracellular matrix. Previously, we showed significant associations of genetic variants in the Syndecan-4 (SDC4) gene with intra-abdominal fat, fasting plasma glucose levels, and insulin sensitivity index in children, and with f...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11112810
更新日期:2019-11-18 00:00:00
abstract::As the population is aging rapidly, there is a strong increase in the number of individuals with chronic disease and physical limitations. The decrease in skeletal muscle mass and function (sarcopenia) and the increase in fat mass (obesity) are important contributors to the development of physical limitations, which a...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10050605
更新日期:2018-05-12 00:00:00
abstract::The objective of the study was to investigate the potential association of human milk leptin concentrations with child body mass index (BMI) and BMI trajectory patterns up to two years of age among children in the Ulm SPATZ Health Study. Leptin concentration was measured in skimmed human milk by ELISA (R&D System). Ch...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11081883
更新日期:2019-08-13 00:00:00
abstract::Iron and vitamin D deficiencies are common during pregnancy. Our aim was to identify whether antenatal vitamin D₃ supplementation affects iron status (via hepcidin suppression) and/or inflammation. Using a subset of the UK multicenter Maternal Vitamin D Osteoporosis Study (MAVIDOS)-a double-blinded, randomized, placeb...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11010190
更新日期:2019-01-18 00:00:00
abstract::Heating oils and fats for a considerable length of time results in chemical reactions, leading to the aggravation of a free radical processes, which ultimately contributes to atherosclerosis. Our study focused on elucidating the effect of feeding heated oils with or without dietary cholesterol on the development of at...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10101527
更新日期:2018-10-17 00:00:00
abstract::A large body of evidence has linked unhealthy eating patterns with an alarming increase in obesity and chronic disease worldwide. However, existing methods of assessing dietary intake in nutritional epidemiology rely on food frequency questionnaires or dietary records that are prone to bias and selective reporting. He...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11102407
更新日期:2019-10-09 00:00:00
abstract::The aim was to evaluate whether the ingestion of a high protein diet containing dairy protein is associated with anthropometric indicators of adiposity and blood glucose. METHODS:A cross-sectional study was conducted with volunteers of 20-89 years of age who performed leisure physical activity. We assessed dietary in...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11061384
更新日期:2019-06-20 00:00:00
abstract::The popularity of yogurt has increased among consumers due to its perceived health benefits. This study examined the cross-sectional association between yogurt consumption and nutrient intake/adequacy, dietary quality, and body weight in children and adults. National Health and Nutrition Examination Survey 2001-2016 d...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12113435
更新日期:2020-11-09 00:00:00
abstract::Harman and norharman, two neuroactive β-carbolines, are present in several plants and in thermally processed foods. They exhibited a wide spectrum of biological and pharmacological effects, including antioxidant, neuroprotective, and anti-inflammatory effects. In this article, we review the progress of recent research...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu11040814
更新日期:2019-04-11 00:00:00
abstract::Cholinergic neurons in the central nervous system play a vital role in higher brain functions, such as learning and memory. Choline is essential for the synthesis of the neurotransmitter acetylcholine by cholinergic neurons. The synthesis and metabolism of acetylcholine are important mechanisms for regulating neuronal...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11102265
更新日期:2019-09-20 00:00:00
abstract::Vegetarian diets have gained popularity in sports. However, few data exist on the status of micronutrients and related biomarkers for vegetarian and vegan athletes. The aim of this cross-sectional study was to compare the micronutrient status of omnivorous (OMN, n = 27), lacto-ovo-vegetarian (LOV, n = 26), and vegan (...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11051146
更新日期:2019-05-22 00:00:00