Abstract:
BACKGROUND:The aim of the present study is to evaluate the association between BMD and type 2 DM status in middle-aged and elderly men. To investigate a possible correlation, the present study used the BMD dataset of the Korea National Health and Nutrition Examination Survey (KNHANES) from 2008 to 2011. METHODS:In total, 37,753 individuals participated in health examination surveys between 2008 and 2011. A total of 3383 males aged ≥50 years were eligible. They underwent BMD measurement through dual-energy X-ray absorptiometry (DXA). The fasting plasma glucose and insulin levels of participants were also measured. RESULTS:Men with prediabetes and diabetes had significantly higher mean BMD at all measured sites than control men did, irrespective of DM status. This was confirmed by multivariable linear regression analyses. DM duration was an important factor affecting BMD. Patients with DM for > 5 years had lower mean BMD in the total hip and femoral neck than those with DM for ≤5 years. Per multivariable linear regression analyses, patients with DM for > 5 years had significantly lower mean BMD at the femoral neck than those with DM ≤5 years. CONCLUSIONS:DM duration was significantly associated with reduced femoral neck BMD.
journal_name
BMC Endocr Disordjournal_title
BMC endocrine disordersauthors
Jang M,Kim H,Lea S,Oh S,Kim JS,Oh Bdoi
10.1186/s12902-018-0290-ysubject
Has Abstractpub_date
2018-09-05 00:00:00pages
61issue
1issn
1472-6823pii
10.1186/s12902-018-0290-yjournal_volume
18pub_type
杂志文章abstract:BACKGROUND:Adipose tissue abundance relies partly on the factors that regulate adipogenesis, i.e. proliferation and differentiation of adipocytes. While components of the transcriptional program that initiates adipogenesis is well-known, the importance of microRNAs in adipogenesis is less well studied. We thus set out ...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-11-7
更新日期:2011-03-22 00:00:00
abstract:BACKGROUND:Non-thyroidal illness syndrome (NTIS) is a characteristic functional constellation of thyrotropic feedback control that frequently occurs in critically ill patients. Although this condition is associated with significantly increased morbidity and mortality, there is still controversy on whether NTIS is cause...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-8-13
更新日期:2008-10-13 00:00:00
abstract:BACKGROUND:Rosiglitazone not only improves insulin-sensitivity, but also exerts anti-inflammatory effects. We have now examined in type 2 diabetic patients if these effects are reflected by changes in mRNA expression in peripheral blood mononuclear cells (PBMCs) to see if these cells can be used to study these anti-inf...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-9-8
更新日期:2009-02-25 00:00:00
abstract:BACGROUND:To assess the contribution of macroprolactin to high serum prolactin levels and their association with thyroid status and thyroid autoimmunity during pregnancy. METHODS:138 pregnant women who suspected of having thyroid dysfunction were studied and divided into three groups according to the thyroid status; g...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-015-0025-2
更新日期:2015-06-20 00:00:00
abstract:BACKGROUND:Caloric restriction is an effective way to treat Type 2 diabetes (T2D). However, chronic and severe restriction of food intake is difficult to sustain and is known to promote slower metabolism. Intermittent and frequent fasting can exert similar metabolic effects, but may be even more challenging for most pa...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-020-00576-7
更新日期:2020-06-24 00:00:00
abstract:BACKGROUND:The prevalence of type 2 diabetes mellitus (T2DM) is expected to increase from 7.7% in 2017 to 8.4% in 2045 worldwide. Diabetes complications contribute to morbidity and mortality. To evaluate whether the diabetes complications severity index (DCSI) was associated with increased risks of mortality and hospit...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-020-00605-5
更新日期:2020-08-10 00:00:00
abstract:BACKGROUND:As an insulin-dependent disease, type 1 diabetes requires paying close attention to the glycemic control. Studies have shown that mobile health (mHealth) can improve the management of chronic diseases. However, the effectiveness of mHealth in controlling the glycemic control remains uncertain. The objective ...
journal_title:BMC endocrine disorders
pub_type: 杂志文章,meta分析
doi:10.1186/s12902-019-0347-6
更新日期:2019-02-13 00:00:00
abstract:BACKGROUND:Radioisotope scanning is important to diagnose subacute thyroiditis (SAT), but it's not always available. So we aim to establish a diagnostic scale for SAT without radioisotope scanning. METHODS:The suspected SAT patients hospitalized in Yuebei people's Hospital from January 2012 to December 2016 were selec...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-020-00554-z
更新日期:2020-05-27 00:00:00
abstract:BACKGROUND:Type 2 diabetes is a common and costly illness, associated with significant morbidity and mortality. Despite this, there is relatively little information on the 'real-world' medication utilization patterns for patients with type 2 diabetes initiating exenatide BID or glargine. The objective of this study was...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-13-20
更新日期:2013-06-22 00:00:00
abstract:UNLABELLED: BACKGROUND:Severe hypoglycaemia (SH) is one of the most feared complications of type 1 diabetes (T1DM) with a reported prevalence of nearly 40%. In randomized trials of Multiple Daily Injections (MDI) and Continuous Subcutaneous Insulin Infusion (CSII) therapy there is a possible benefit of CSII in reducin...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-12-33
更新日期:2012-12-13 00:00:00
abstract:BACKGROUND:A growing body of evidence supports neutrophils as having an active role in the development of diabetic kidney disease (DKD). However, the clinical relevance of neutrophils and DKD in autoimmune diabetes remains unknown. This study aimed to investigate the relationship between circulating neutrophils and DKD...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-020-00597-2
更新日期:2020-10-22 00:00:00
abstract:BACKGROUND:Type 2 diabetes mellitus (T2DM) and several types of neurodegeneration, including Alzheimer's, are linked to insulin-resistance, and chronic high dietary fat intake causes T2DM with mild neurodegeneration. Intra-cerebral Streptozotocin, a nitrosamine-related compound, causes neurodegeneration, whereas periph...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-10-4
更新日期:2010-03-19 00:00:00
abstract:BACKGROUND:Medullary thyroid carcinoma is a malignant uncommon and aggressive tumour of the parafollicular C cells. In about 75% of cases it is sporadic while, in case of RET mutation, it is associated to multiple endocrine neoplasia type 2 (25% of cases). The biochemical features of medullary thyroid carcinoma include...
journal_title:BMC endocrine disorders
pub_type: 杂志文章,评审
doi:10.1186/s12902-019-0435-7
更新日期:2019-10-16 00:00:00
abstract:BACKGROUND:Sympathetic activity and insulin resistance have recently been linked with chronic tendon and musculoskeletal pain. Polycystic ovarian syndrome is linked with insulin resistance and increased sympathetic drive and was therefore an appropriate condition to study the effects of modulating sympathetic activity ...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-020-00610-8
更新日期:2020-08-26 00:00:00
abstract:BACKGROUND:Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms are not fully understood. This study investigated the effects of type 1 diabetes (T1D), type 2 diabet...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-019-0350-y
更新日期:2019-02-08 00:00:00
abstract:BACKGROUND:The hypertension cure rate of unilateral adrenalectomy in primary aldosteronism (PA) patients varies widely in existing studies. METHODS:We conducted an observational meta-analysis to summarize the pooled hypertension cure rate of unilateral adrenalectomy in PA patients. Comprehensive electronic searches of...
journal_title:BMC endocrine disorders
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12902-017-0209-z
更新日期:2017-10-03 00:00:00
abstract:BACKGROUND:We quantified, among diabetic adults, the frequency, costs, and factors associated with visits to the emergency department (EDs) and subsequent hospitalizations for acute hypoglycaemic and hyperglycaemic events. METHODS:We included adults with diabetes residing in the Milan Agency for Health Protection betw...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-020-0546-1
更新日期:2020-05-19 00:00:00
abstract:BACKGROUND:Diabetes mellitus is usually preceded by a pre-diabetic stage before the clinical presentation of the disease, the influence of which on persons' quality of life is not adequately elucidated. The purpose of this study was to compare the Health-Related Quality of Life (HRQOL) of persons with pre-diabetes with...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-018-0261-3
更新日期:2018-05-29 00:00:00
abstract:BACKGROUND:Islet cell transplantation is a method to stabilize type 1 diabetes patients with hypoglycemia unawareness and unstable blood glucose levels by reducing insulin dependency and protecting against severe hypoglycemia through restoring endogenous insulin secretion. This study analyses the current cost-effective...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-016-0097-7
更新日期:2016-04-09 00:00:00
abstract:BACKGROUND:Hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome is a rare autosomal dominant disorder caused by mutations in the zinc finger transcription factor gene, GATA3. GATA3 has 2 zinc finger domains, which play an important role in the increase in target gene transcription activity. CASE PRESENTATI...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-015-0065-7
更新日期:2015-10-30 00:00:00
abstract:BACKGROUND:Self- management is vital to the control of diabetes. This study aims to assess the diabetes self-care behaviours of patients attending two tertiary hospitals in Gauteng, South Africa. The study also seeks to estimate the inequalities in adherence to diabetes self-care practices and associated factors. METH...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-020-0492-y
更新日期:2020-01-28 00:00:00
abstract:BACKGROUND:Early identification of children and adolescents with type 1 diabetes at high risk for development of complications is important, as early intervention may prevent further deterioration. Here we investigate the applicability of assessing skin advanced glycation end products (sAGEs) by skin autofluorescence (...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-016-0129-3
更新日期:2016-09-09 00:00:00
abstract:BACKGROUND:Spontaneous haemorrhage into a parathyroid adenoma is a rare and potentially life-threatening presentation. CASE PRESENTATION:We report the case of a 45 year old female recently diagnosed with primary hyperparathyroidism who presented with chest discomfort and acute airway compromise due to spontaneous extr...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-017-0186-2
更新日期:2017-06-21 00:00:00
abstract:BACKGROUND:Most of the patients with type 1 and V hyperlipoproteinemia (HLP) present with symptoms and signs of acute pancreatitis due to marked elevation of triglycerides, but this baby presented with a chest infection, which was later diagnosed as type V HLP on laboratory workup. CASE PRESENTATION:We report a case o...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-020-0502-0
更新日期:2020-02-11 00:00:00
abstract:BACKGROUND:Type 2 diabetic patients display significantly higher incidence of cardiovascular (CV) events including stroke compared to non-diabetics. Morning blood pressure surge (MBPS) and blunted systolic night-day (SND) ratio have been associated with CV events in hypertensive patients. No studies have evaluated MBPS...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-015-0068-4
更新日期:2015-12-03 00:00:00
abstract:BACKGROUND:Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder, and its pathogenesis is still under debate. Trimethylamine-N-oxide (TMAO) is a small, organic compound generated by the gut microbiome with a hypothesized relation to insulin resistance (IR) and low-grade inflammation in PCOS. By compar...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-019-0486-9
更新日期:2020-01-06 00:00:00
abstract:BACKGROUND:Thyrotoxicosis is often caused by destructive thyroiditis (DT) or Graves' disease (GD), and a prompt and accurate differential diagnosis for thyrotoxicosis is needed as management strategy differs. A meta-analysis of published literature was performed to evaluate the diagnostic accuracy for differentiating G...
journal_title:BMC endocrine disorders
pub_type: 杂志文章,meta分析
doi:10.1186/s12902-019-0388-x
更新日期:2019-06-06 00:00:00
abstract:BACKGROUND:To estimate the proportion of diabetic patients (DPts) with peripheral vascular disease treated at a primary health care site after an endocrinologist-based intervention, who meet ATP III and Steno targets of metabolic control, as well as to compare the outcome with the results of the patients treated by end...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-8-9
更新日期:2008-07-31 00:00:00
abstract:BACKGROUND:Alogliptin is a new dipeptidyl peptidase (DPP-4) inhibitor, which is under investigation for treatment of type 2 diabetes either alone or in combination with other antidiabetic drugs. The aim of this meta-analysis was to assess the efficacy and tolerability of alogliptin in patients with type 2 diabetes. ME...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/1472-6823-13-9
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Previous studies have shown inconsistent results about the usefulness of bilateral inferior petrosal sinus sampling (BIPSS) in differential diagnosis of adrenocorticotropic hormone (ACTH)-dependent Cushing syndrome. This meta-analysis evaluated the diagnostic value of BIPSS via the published literature. MET...
journal_title:BMC endocrine disorders
pub_type: 杂志文章
doi:10.1186/s12902-020-00623-3
更新日期:2020-09-17 00:00:00