Abstract：
:The interaction of dietary and genetic factors may affect the development of bone deterioration. This study investigated whether the effects of dietary acid load (DAL) on bone loss in postmenopausal Chinese women were moderated by the insulin-like growth factor-1 (IGF-1) single nucleotide polymorphism, a known gene that plays a role in the regulation of bone formation and bone remodeling. A total of 217 healthy participants were recruited from the National Council of Senior Citizens Organizations Malaysia. Serum collagen type 1 cross-linked C-telopeptide was used as a surrogate bone marker to assess bone resorption and Agena® MassARRAY genotyping analysis was used to identify the signaling of IGF-1 rs35767. The dietary acid load was measured by potential renal acid load score while physical activity was ascertained using the Global Physical Activity Questionnaire. Hierarchical regression was applied to test the main and interaction effects of DAL and IGF-1 genotypes in bone resorption. The result supported the diet-dependent acid-base balance theory that higher DAL was positively associated with bone resorption (β = 0.152, p = 0.031, F(6,207) = 2.11, sig-F = 0.036, R² = 0.079). However, the results indicated that there was no significant correlation between IGF-1 and bone resorption, or any significant interaction between DAL and IGF-1. In conclusion, there was no moderating effect of IGF-1 on the relationship between DAL and bone resorption.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Lim SY,Zalilah MS,Chin YS,Ramachandran V,Chan YMdoi
10.3390/nu10070915subject
Has Abstractpub_date
2018-07-17 00:00:00issue
7issn
2072-6643pii
nu10070915journal_volume
10pub_type
杂志文章相关文献
Nutrients文献大全abstract：:Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are increased in plasma lipids and blood cell membranes in response to supplementation. Whilst arachidonic acid (AA) is correspondingly decreased, the effect on other fatty acids (FA) is less well described and there may be site-specific differences. In respon...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu7085285
更新日期：2015-08-03 00:00:00
abstract：:Reducing salt intake is a cost-effective public health intervention to reduce the global burden of non-communicable disease (NCDs). Ultra-processed foods contribute ~80% of dietary salt in high income countries, and are becoming prominent in low-middle income countries. Instant noodle consumption is particularly high ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu9060612
更新日期：2017-06-16 00:00:00
abstract：:Previous research indicated that preschoolers of lower socioeconomic status (SES) consume less healthy beverages than high SES preschoolers. The purpose of this study is to investigate the mediating role of parenting practices in the relationship between SES and plain water, soft drink and prepacked fruit juice (FJ) c...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu8100591
更新日期：2016-09-23 00:00:00
abstract：:A high intake of refined carbohydrates, particularly the monosaccharide fructose, has been attributed to the growing epidemics of obesity and type-2 diabetes. Animal studies have helped elucidate the metabolic effects of dietary fructose, however, variations in study design make it difficult to draw conclusions. The a...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu8090577
更新日期：2016-09-20 00:00:00
abstract：:The polyphenol resveratrol (RVT) may drive protective mechanisms of cerebral homeostasis during the hypoperfusion/reperfusion triggered by the transient bilateral common carotid artery occlusion followed by reperfusion (BCCAO/R). This immunochemical study investigates if a single dose of RVT modulates the plasticity-r...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11051000
更新日期：2019-05-01 00:00:00
abstract：:Dietary habits in adolescence persist into adulthood; thus, it is important to identify the factors that influence adolescent diet and establish a healthy diet. This study aimed to examine the association between mothers' nutrition knowledge and their children's nutrient intake inadequacy among Japanese junior high sc...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12092801
更新日期：2020-09-13 00:00:00
abstract：:The American Heart Association (AHA) has advocated that women and men not consume more than 100 and 150 kcal/day, respectively, from added sugars. These levels are currently exceeded by over 90% of the adult population in the United States. Few data exist on longer-term metabolic effects when sucrose and High Fructose...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu6031128
更新日期：2014-03-17 00:00:00
abstract：:The effects of different carbohydrate-protein (CHO + Pro) beverages were compared during recovery from cycling exercise. Twelve male cyclists (VO(2peak): 65 ± 7 mL/kg/min) completed ~1 h of high-intensity intervals (EX1). Immediately and 120 min following EX1, subjects consumed one of three calorically-similar beverag...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu4070568
更新日期：2012-07-01 00:00:00
abstract：:Previous studies have reported that maternal malnutrition is linked to increased risk of developing type 2 diabetes in adulthood. Although several diabetic risk factors associated with early-life environment have been identified, protective factors remain elusive. Here, we conducted a longitudinal study with 671 Nile ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu13010094
更新日期：2020-12-30 00:00:00
abstract：:Globally, childhood undernutrition continues to be a major public health concern, with an estimated 165 million children classified as stunted and 51.5 million suffering from acute malnutrition.[...]. ...
journal_title：Nutrients
pub_type： 社论
doi：10.3390/nu8100603
更新日期：2016-09-27 00:00:00
abstract：:Plant-based diets are associated with reduced risk of lifestyle-induced chronic diseases. The thousands of phytochemicals they contain are implicated in cellular-based mechanisms to promote antioxidant defense and reduce inflammation. While recommendations encourage the intake of fruits and vegetables, most people fal...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu12102929
更新日期：2020-09-24 00:00:00
abstract：:This study investigated the effects of a single dose of arginine (Arg) administration at the beginning of sepsis on CD4+ T-cell regulation and liver inflammation in C57BL/6J mice. Mice were divided into normal control (NC), sham (SH), sepsis saline (SS), and sepsis Arg (SA) groups. An inducible nitric oxide (NO) synth...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12041047
更新日期：2020-04-10 00:00:00
abstract：:Deoxyschizandrin, a major lignan of Schisandra berries, has been demonstrated to have various biological activities such as antioxidant, hepatoprotective, and antidiabetic effects. However, the anti-cancer effects of deoxyschizandrin are poorly characterized. In the present study, we investigated the anti-cancer effec...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10010091
更新日期：2018-01-15 00:00:00
abstract：:Hypertension is affected by both genetic and dietary factors. This study aimed to examine the interaction between dietary sodium/potassium intake, sodium-potassium ratios, and FGF5 rs16998073 and link these with increased risk for developing hypertension. Using data from the Health Examinee (HEXA) Study of the Korean ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12072121
更新日期：2020-07-17 00:00:00
abstract：:The objective of the present study is to analyze the effects of motor mental imagery training on tennis service performance among tennis athletes who fast during Ramadan. Participants were 38 young male tennis players, randomly divided into two groups: Imaging Training (IMG, n = 18) and control group (CG, n = 20). The...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12041035
更新日期：2020-04-09 00:00:00
abstract：:Flavonoids are a class of polyphenolic compounds that naturally occur in plants. Sub-groups of flavonoids include flavone, flavonol, flavanone, flavanonol, anthocyanidin, flavanol and isoflavone. The various modifications on flavonoid molecules further increase the diversity of flavonoids. Certain crops are famous for...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu12061717
更新日期：2020-06-08 00:00:00
abstract：:Nutritional supplements which include natural antitumoral compounds could represent safe and efficient additives for cancer patients. One such nutritional supplement, Ocoxin Oral solution (OOS), is a composite formulation that contains several antioxidants and exhibits antitumoral properties in several in vitro and in...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11051068
更新日期：2019-05-14 00:00:00
abstract：BACKGROUND:Zinc is an essential micronutrient for human beings and its deficiency affects their normal growth and development. OBJECTIVE:The main aim was to evaluate the effect of two doses of zinc supplementation (ZS) on the nutritional status in chronic kidney disease (CKD) children. METHODS:A randomized-trial mult...
journal_title：Nutrients
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.3390/nu11112671
更新日期：2019-11-05 00:00:00
abstract：:The number of people suffering from constant tinnitus is ever-increasing and has spread to all age groups, including adolescents. The etiology of tinnitus is multifactorial, but dietary factors have been rarely investigated. The purpose of this study is to examine the relationship between dietary factors and constant ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12113291
更新日期：2020-10-27 00:00:00
abstract：:Decreased renal function, elevated circulating levels of urea, intestinal levels of urea-degrading bacteria, and gut-derived uremic metabolites are present in end-stage renal disease (ESRD), a cohort that has reduced muscle mass and physical function, and poor muscle composition. This phenotype, defined as the kidney-...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12010106
更新日期：2019-12-30 00:00:00
abstract：:Environmental factors such as food availability and variety can function as cues for overeating in individuals susceptible to overweight or obesity, but relatively little is known about other types of environmental factors that may also be important. This qualitative study compared and contrasted categories of interna...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11061365
更新日期：2019-06-18 00:00:00
abstract：:The inherited metabolic disease phenylketonuria (PKU) is characterized by increased concentrations of phenylalanine in the blood and brain, and as a consequence neurotransmitter metabolism, white matter, and synapse functioning are affected. A specific nutrient combination (SNC) has been shown to improve synapse forma...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu8040185
更新日期：2016-03-26 00:00:00
abstract：:Advanced glycation endproducts (AGEs) can be found in protein- and sugar-rich food products processed at high temperatures, which make up a vast amount of the Western diet. The effect of AGE-rich food products on human health is not yet clear and controversy still exists due to possible contamination of samples with e...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10121868
更新日期：2018-12-02 00:00:00
abstract：:Child-targeted food marketing is a significant public health concern, prompting calls for its regulation. Product packaging is a powerful form of food marketing aimed at children, yet no published studies examine the range of literature on the topic or the "power" of its marketing techniques. This study attempts such ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12040958
更新日期：2020-03-30 00:00:00
abstract：:Obesity, a recognized risk factor for breast cancer in postmenopausal women, is associated with higher mortality rates regardless of menopausal status, which could in part be explained by therapeutic escape. Indeed, adipose microenvironment has been described to influence the efficiency of chemo- and hormonal therapie...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11122839
更新日期：2019-11-20 00:00:00
abstract：:The moderate consumption of fish is recommended for a healthy diet and is also a feature of the Mediterranean diet. Fish is a major food group in diets throughout the world, and studies show that fish consumption is associated with a lower risk of a number of conditions. Spain has one of the highest annual per capita ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu5010010
更新日期：2012-12-27 00:00:00
abstract：:Zinc deficiency has serious wide-ranging health consequences and is thought to be one of the most prevalent micronutrient deficiencies in the world. However, reliable indicators or biomarkers to assess zinc status are not available at present. Indirect indicators such as the prevalence of stunting or anemia, iron defi...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu7053252
更新日期：2015-05-06 00:00:00
abstract：:Many Americans are attempting to lose weight with the help of healthcare professionals. Clinicians can improve weight loss results by using technology. Accurate dietary assessment is crucial to effective weight loss. The aim of this study was to validate a computer-led dietary assessment method in overweight/obese wom...
journal_title：Nutrients
pub_type： 临床试验,杂志文章
doi：10.3390/nu9030218
更新日期：2017-03-01 00:00:00
abstract：:The study objectives were to examine total and individual lignan intakes and their dietary sources in postmenopausal Polish women and to investigate the relationship between lignan intake and the prevalence of cardiovascular disease (CVD), hypertension, hypercholesterolemia and central obesity. A total of 2599 postmen...
journal_title：Nutrients
pub_type： 杂志文章,多中心研究
doi：10.3390/nu10070865
更新日期：2018-07-04 00:00:00
abstract：:Osteoarthritis (OA) is considered one of the most common joint disorders worldwide and its prevalence is constantly increasing due to the global longevity and changes in eating habits and lifestyle. In this context, the role of gut microbiota (GM) in the pathogenesis of OA is still unclear. Perturbation of GM biodiver...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu12020574
更新日期：2020-02-22 00:00:00
