Kaposi's sarcoma of the conjunctiva and the eyelid leads to the diagnosis of human immunodeficiency virus infection - a case report.

abstract：BACKGROUND:The aim of this study was to investigate the incidence and prognostic value of disseminated tumor cells in bone marrow of breast carcinoma patients with early disease, and to analyze this finding in relation to lymph node involvement, determined by sentinel lymph node (SLN) biopsy analysis, and to prognostic...

journal_title：BMC cancer

authors： Solá M,Margelí M,Castellá E,Julian JF,Rull M,Gubern JM,Mariscal A,Barnadas A,Fraile M

更新日期：2011-06-16 00:00:00

abstract：BACKGROUND:We sought to determine the comparative diagnostic performance of standard b-value (800-1000 s/mm2) versus low b-value (400-500 s/mm2) diffusion-weighted magnetic resonance imaging (DW-MRI) in the detection of renal cell carcinoma (RCC). METHOD:After a systematic review of the available literature, studies w...

journal_title：BMC cancer

authors： Tang Y,Zhou Y,Du W,Liu N,Zhang C,Ouyang T,Hu J

更新日期：2014-11-18 00:00:00

abstract：OBJECTIVE:C-reactive protein (CRP) is considered a useful serum marker for patients with RCC. However, its clinical utility in advanced metastatic renal cell carcinoma (AM-RCC), particularly in deciding whether to perform nephrectomy at the onset, is not well studied. PATIENTS AND METHODS:We retrospectively evaluated ...

journal_title：BMC cancer

authors： Ito H,Shioi K,Murakami T,Takizawa A,Sano F,Kawahara T,Mizuno N,Makiyama K,Nakaigawa N,Kishida T,Miura T,Kubota Y,Yao M

更新日期：2012-08-02 00:00:00

abstract：BACKGROUND:Anchoring filament protein ladinin-1 (LAD1) was related to the aggressive progression of breast, lung, laryngeal and thyroid cancers. However, the association of LAD1 with colorectal cancer remained unknown. Here, to determine the relationship of LAD1 with colorectal cancer progression, we explored the effec...

journal_title：BMC cancer

authors： Moon B,Yang SJ,Park SM,Lee SH,Song KS,Jeong EJ,Park M,Kim JS,Yeom YI,Kim JA

更新日期：2020-12-02 00:00:00

abstract：BACKGROUND:Malignant pleural mesothelioma (MPM) is a tumor known to be resistant to conventional therapies. Thus, an in vivo model can represent an important tool for assessing the efficacy of novel approaches in the treatment of MPM.Presently, human MPM cells have been grown orthotopically in mice upon transplantation...

journal_title：BMC cancer

authors： Martarelli D,Catalano A,Procopio A,Orecchia S,Libener R,Santoni G

更新日期：2006-05-17 00:00:00

abstract：BACKGROUND:The neutrophil-to-lymphocyte ratio (NLR), a simple marker of the systemic inflammatory response in critical care patients, has been suggested as an independent prognostic factor for several solid malignancies. We investigated the utility of pretreatment NLR as a prognosticator in patients who presented with ...

journal_title：BMC cancer

authors： Kawahara T,Yokomizo Y,Ito Y,Ito H,Ishiguro H,Teranishi J,Makiyama K,Miyoshi Y,Miyamoto H,Yao M,Uemura H

更新日期：2016-02-16 00:00:00

abstract：BACKGROUND:Pneumatosis cystoides intestinalis (PCI) is a rare self-limiting condition characterized by air-filled cysts within intestinal walls. Diagnosis should be prudent because it can mimic pneumoperitoneum leading to unnecessary treatment such as surgical exploration. Although various drugs including anti-neoplast...

journal_title：BMC cancer

authors： Lee YS,Han JJ,Kim SY,Maeng CH

更新日期：2017-11-09 00:00:00

abstract：BACKGROUND:One of the basic prerequisites for generating evidence-based data is the availability of classification systems. Attempts to date to classify breast cancer operations have focussed on specific problems, e.g. the avoidance of secondary corrective surgery for surgical defects, rather than taking a generic appr...

journal_title：BMC cancer

authors： Hoffmann J,Wallwiener D

更新日期：2009-04-08 00:00:00

abstract：BACKGROUND:This study is designed to investigate the clinical value of systemic chemotherapy combined with bronchoscopic interventional cryotherapy in the treatment of lung cancer. METHODS:A total of 412 lung cancer patients admitted to Cangzhou People's Hospital from March 2018 to March 2020 were collected and divide...

journal_title：BMC cancer

authors： Xu F,Song J,Xu B,Wang J,Mao J,Liu H,Li X,Deng A

更新日期：2020-11-11 00:00:00

abstract：BACKGROUND:Acute myeloid leukemia (AML) is predominantly a disease of older patients with a poor long-term survival. Approval of decitabine (DAC) in the European Union (EU) in 2012 for the treatment of patients with AML ≥65 years marks the potential for hypomethylating agents in elderly AML. Nevertheless the situation ...

journal_title：BMC cancer

authors： Grishina O,Schmoor C,Döhner K,Hackanson B,Lubrich B,May AM,Cieslik C,Müller MJ,Lübbert M

更新日期：2015-05-26 00:00:00

abstract：BACKGROUND:The prognostic value of histone γ-H2AX and 53BP1 proteins to predict the radiotherapy (RT) outcome of patients with rectal carcinoma (RC) was evaluated in a prospective study. High expression of the constitutive histone γ-H2AX is indicative of defective DNA repair pathway and/or genomic instability, whereas ...

journal_title：BMC cancer

authors： Djuzenova CS,Zimmermann M,Katzer A,Fiedler V,Distel LV,Gasser M,Waaga-Gasser AM,Flentje M,Polat B

更新日期：2015-11-06 00:00:00

abstract：BACKGROUND:It has been previously demonstrated in several cancer models, that Dronabinol (THC) may have anti-tumor activity--however, controversial data exists for acute leukemia. We have anecdotal evidence that THC may have contributed to disease control in a patient with acute undifferentiated leukemia. METHODS:To t...

journal_title：BMC cancer

authors： Kampa-Schittenhelm KM,Salitzky O,Akmut F,Illing B,Kanz L,Salih HR,Schittenhelm MM

更新日期：2016-01-16 00:00:00

abstract：BACKGROUND:BRAF-activated noncoding RNA (BANCR) is aberrantly expressed in various tumor tissues and has been confirmed to function as a tumor suppressor or oncogene in many types of cancers. Considering the conflicting results and insufficient sampling, a meta-analysis was performed to explore the prognostic value of ...

journal_title：BMC cancer

authors： Fang S,Liu Z,Guo Q,Chen C,Ke X,Xu G

更新日期：2020-09-09 00:00:00

abstract：BACKGROUND:Genomic initiatives such as The Cancer Genome Atlas (TCGA) contain data from -omics profiling of thousands of tumor samples, which may be used to decipher cancer signaling, and related alterations. Managing and analyzing data from large-scale projects, such as TCGA, is a demanding task. It is difficult to di...

journal_title：BMC cancer

authors： Lucchetta M,da Piedade I,Mounir M,Vabistsevits M,Terkelsen T,Papaleo E

更新日期：2019-08-20 00:00:00

abstract：BACKGROUND:DNA methylation changes occurring in cancer cells are featured with both promoter CpG island hypermethylation and diffuse genomic hypomethylation. Long interspersed element-1 (LINE-1) is repeated in an interspersed manner with an estimated 500,000 copies per genome. LINE-1 has its CpG sites of the 5' untrans...

journal_title：BMC cancer

authors： Jeong S,Lee K,Wen X,Kim Y,Cho NY,Jang JJ,Kang GH

更新日期：2017-08-29 00:00:00

abstract：BACKGROUND:Malignant glioma is a common primary tumor of the central nervous system. Brevican, an abundant extracellular matrix component in the adult brain, plays a critical role in the process of glioma. The mechanisms for the highly invasive behavior of gliomas are still poorly understood. The aim of this study was ...

journal_title：BMC cancer

authors： Lu R,Wu C,Guo L,Liu Y,Mo W,Wang H,Ding J,Wong ET,Yu M

更新日期：2012-12-19 00:00:00

abstract：BACKGROUND:Classical in vitro wound-healing assays and other techniques designed to study cell migration and invasion have been used for many years to elucidate the various mechanisms associated with metastasis. However, many of these methods are limited in their ability to achieve reproducible, quantitative results th...

journal_title：BMC cancer

authors： Kam Y,Guess C,Estrada L,Weidow B,Quaranta V

更新日期：2008-07-14 00:00:00

abstract：BACKGROUND:Peritoneal dissemination is the most common type of recurrence in advanced gastric cancer. The main mechanism is thought to be via the exfoliation of free cancer cells (FCCs) from tumor in the gastric serosa. The frequency of recurrence thus increases once the tumor cells penetrate the serosa. However, this ...

journal_title：BMC cancer

authors： Huang B,Sun Z,Wang Z,Lu C,Xing C,Zhao B,Xu H

更新日期：2013-02-04 00:00:00

abstract：BACKGROUND:Women with ovarian cancer can present with a variety of symptoms and signs, and an increasing range of tests are available for their investigation. A number of international guidelines provide advice for the initial assessment of possible ovarian cancer in symptomatic women. We systematically identified and ...

journal_title：BMC cancer

authors： Funston G,Van Melle M,Baun ML,Jensen H,Helsper C,Emery J,Crosbie EJ,Thompson M,Hamilton W,Walter FM

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Ectopic TSH-secreting pituitary adenoma (TSH-oma) is a very unusual disorder. To date, there are only four cases reported. It is difficult to distinguish ectopic cases from both regular TSH-omas and resistance to thyroid hormone (RTH). CASE PRESENTATION:A newly identified case of ectopic TSH-oma arising fro...

journal_title：BMC cancer

authors： Song M,Wang H,Song L,Tian H,Ge Q,Li J,Zhu Y,Li J,Zhao R,Ji HL

更新日期：2014-07-28 00:00:00

abstract：BACKGROUND:Local control in malignant salivary gland tumours is dose dependent. High local control rates in adenoid cystic carcinomas could be achieved by highly conformal radiotherapy techniques and particle (neutron/carbon ion) therapy. Considering high doses are needed to achieve local control, all malignant salivar...

journal_title：BMC cancer

authors： Jensen AD,Nikoghosyan A,Windemuth-Kieselbach C,Debus J,Münter MW

更新日期：2010-10-11 00:00:00

abstract：BACKGROUND:Biannual ultrasound (US)-with or without alpha-fetoprotein (AFP)-is recommended by current guidelines for the surveillance of hepatocellular carcinoma (HCC). However, the inadequate sensitivity of US has been a concern. Magnetic resonance imaging (MRI) is known to have high sensitivity in detecting hepatic m...

journal_title：BMC cancer

authors： An C,Kim DY,Choi JY,Han KH,Roh YH,Kim MJ

更新日期：2018-09-24 00:00:00

abstract：BACKGROUND:Lymphangiogenesis has become a new research frontier in tumor metastasis since the discovery of reliable lymphatic markers that have allowed observation and isolation of lymphatic endothelium. Cyclooxygenase-2 (COX-2) has been reported to be involved in the critical steps in carcinogenesis. However, possible...

journal_title：BMC cancer

authors： Zhang XH,Huang DP,Guo GL,Chen GR,Zhang HX,Wan L,Chen SY

更新日期：2008-01-13 00:00:00

abstract：BACKGROUND:Little is known about colorectal adenoma patients' ability to adhere to behavioural interventions promoting a change in diet and physical activity. This review aimed to examine health behaviour intervention programmes promoting change in diet and/or physical activity in adenoma patients and characterise inte...

journal_title：BMC cancer

authors： McCahon D,Daley AJ,Jones J,Haslop R,Shajpal A,Taylor A,Wilson S,Dowswell G

更新日期：2015-07-07 00:00:00

abstract：BACKGROUND:The purpose of the PROLUCA study is to investigate the efficacy of preoperative and early postoperative rehabilitation in a non-hospital setting in patients with operable lung cancer with special focus on exercise. METHODS:Using a 2 x 2 factorial design with continuous effect endpoint (Maximal Oxygen Uptake...

journal_title：BMC cancer

authors： Sommer MS,Trier K,Vibe-Petersen J,Missel M,Christensen M,Larsen KR,Langer SW,Hendriksen C,Clementsen P,Pedersen JH,Langberg H

更新日期：2014-06-04 00:00:00

abstract：BACKGROUND:The effect of current therapies in improving the survival of lung cancer patients remains far from satisfactory. It is consequently desirable to find more appropriate therapeutic opportunities based on informed insights. A molecular pharmacological analysis was undertaken to design an improved chemotherapeut...

journal_title：BMC cancer

authors： Gemma A,Li C,Sugiyama Y,Matsuda K,Seike Y,Kosaihira S,Minegishi Y,Noro R,Nara M,Seike M,Yoshimura A,Shionoya A,Kawakami A,Ogawa N,Uesaka H,Kudoh S

更新日期：2006-06-30 00:00:00

abstract：BACKGROUND:Metastasis is the main cause of death for lung cancer patients. The ex vivo 4D acellular lung model has been shown to mimic this metastatic process. However, the main concern is the model's lack of cellular components of the tumor's microenvironment. In this study, we aim to determine if the intact lung micr...

journal_title：BMC cancer

authors： Mishra DK,Miller RA,Pence KA,Kim MP

更新日期：2018-04-18 00:00:00

abstract：BACKGROUND:Endometrial cancer, one of the most common malignant tumors, is a serious threat to women's health. Endometrial hyperplasia is a precursor of endometrial cancer. S100 calcium binding protein P (S100P) has been found to play important roles in many types of cancer. The present study aimed to investigate the e...

journal_title：BMC cancer

authors： Zhang D,Chen X,Xia H,Wang L,Zhao H,Xu B,Zhang A,Zhang W

更新日期：2020-09-03 00:00:00

abstract：BACKGROUND:Oncolytic viruses represent a promising therapy against cancers with acquired drug resistance. However, low efficacy limits its clinical application. The objective of this study is to investigate whether pharmacologically modulating autophagy could enhance oncolytic Newcastle disease virus (NDV) strain NDV/F...

journal_title：BMC cancer

authors： Jiang K,Li Y,Zhu Q,Xu J,Wang Y,Deng W,Liu Q,Zhang G,Meng S

更新日期：2014-07-30 00:00:00

abstract：BACKGROUND:Oncotype DX® (ODX) is used to assess risk of disease recurrence in hormone receptor positive, HER2-negative breast cancer and to guide decisions regarding adjuvant chemotherapy. Little is known about how physician factors impact treatment decisions. The purpose of this study was to examine patient and physic...

journal_title：BMC cancer

authors： Schwedhelm TM,Rees JR,Onega T,Zipkin RJ,Schaefer A,Celaya MO,Moen EL

更新日期：2020-09-03 00:00:00