Abstract:
BACKGROUND:Due to a lack of survey of health care seeking behavior for influenza, the actual magnitude of influenza in Beijing of China has not been well described. METHODS:During 2013-2014 influenza season, two cross-sectional household surveys were carried out respectively during the epidemic and non-epidemic season of influenza. A structured survey was undertaken with individuals who were ≥18 years selected by a multistage random sampling method in the study. Health care seeking behaviors were then examined to estimate the actual case number of influenza, using a multiplier model. RESULTS:A total of 14,665 adults were interviewed. 61.9% of ILI cases consulted a physician. The consultation rate during epidemic period is higher than that during non-epidemic period (67.9% vs. 52.3%). Similarly, the proportion of healthcare usage of general hospital during epidemic period is higher than that was during non-epidemic period (27.1% vs. 19.0%, p = 0.008). Lack of insurance and education reduced healthcare seeking significantly in this study. It was estimated that there were 379,767 (90% CI = [281,934, 526,565]) confirmed cases of influenza amongst adults in Beijing, during 2013-2014 influenza season, with an incidence rate of 2.0%. CONCLUSIONS:The surveillance system for ILI and virological data has the potential to provide baseline case number to estimate the actual annual magnitude of influenza. Given the changes in healthcare seeking behavior over time, sentinel surveillance on healthcare seeking behavior are required to be established for better estimate of the true case number of influenza.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
Wang X,Wu S,Yang P,Li H,Chu Y,Tang Y,Hua W,Zhang H,Li C,Wang Qdoi
10.1186/s12879-017-2217-zsubject
Has Abstractpub_date
2017-02-03 00:00:00pages
120issue
1issn
1471-2334pii
10.1186/s12879-017-2217-zjournal_volume
17pub_type
杂志文章abstract:BACKGROUND:Antiretroviral therapy (ART) markedly reduces HIV transmission, and testing and treatment programs have been advocated as a method for decreasing transmission at the population level. Little is known, however, about the extent to which sexually transmitted infections (STIs), which increase the HIV infectious...
journal_title:BMC infectious diseases
pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12879-015-0961-5
更新日期:2015-06-30 00:00:00
abstract:BACKGROUND:Little is known about the morbidity and mortality of invasive fungal disease (IFD) at a population level. The aim of this study was to determine the incidence, trends and outcomes of IFD in all haematology-oncology patients by linking Victorian hospital data to state-based registries. METHODS:Episodes of IF...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-3901-y
更新日期:2019-03-21 00:00:00
abstract:BACKGROUND:Indirect herd effect from vaccination of children offers potential for improving the effectiveness of influenza prevention in the remaining unvaccinated population. Static models used in cost-effectiveness analyses cannot dynamically capture herd effects. The objective of this study was to develop a methodol...
journal_title:BMC infectious diseases
pub_type: 杂志文章,meta分析
doi:10.1186/1471-2334-13-25
更新日期:2013-01-22 00:00:00
abstract:BACKGROUND:Mycobacterium tuberculosis can enter into a dormant state which has resulted in one third of the world's population being infected with latent tuberculosis making the study of latency and reactivation of utmost importance. M. tuberculosis encodes five resuscitation promoting factors (Rpfs) that bear strong s...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-7-146
更新日期:2007-12-17 00:00:00
abstract:BACKGROUND:Dengue fever and leptospirosis have partially overlapping geographic distributions, similar clinical presentations and potentially life-threatening complications but require different treatments. Distinguishing between these cosmopolitan emerging pathogens represents a diagnostic dilemma of global importance...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-14-35
更新日期:2014-01-20 00:00:00
abstract:BACKGROUND:Uganda has experienced seven Ebola Virus Disease (EVD) outbreaks and four Marburg Virus Disease (MVD) outbreaks between 2000 and 2019. We investigated the seroprevalence and risk factors for Marburg virus and ebolaviruses in gold mining communities around Kitaka gold mine in Western Uganda and compared them ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-020-05187-0
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Variations of porB1A and porB1B genes and their serotypes exist in Neisseria gonorrhoeae isolates from different geographical areas, and some site mutations in the porB1B gene correlate with drug resistance. METHODS:The β-lactamase production of N. gonorrhoeae isolates was determined by paper acidometric te...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-10-323
更新日期:2010-11-10 00:00:00
abstract:BACKGROUND:Young people are disproportionately affected by sexually transmissible infections in Australia but face barriers to accessing sexual health services, including concerns over confidentiality and, for some, geographic remoteness. A possible innovation to increase access to services is the use of telemedicine. ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-11-285
更新日期:2011-10-25 00:00:00
abstract:BACKGROUND:Annual influenza vaccination of healthcare workers (HCWs) is recommended in Australia, but uptake in healthcare facilities has historically been low (approximately 50%). The objective of this study was to develop and implement a dedicated campaign to improve uptake of staff influenza annual vaccination at a ...
journal_title:BMC infectious diseases
pub_type: 杂志文章,多中心研究
doi:10.1186/s12879-015-0765-7
更新日期:2015-02-06 00:00:00
abstract:BACKGROUND:Ureaplasma urealyticum is a fastidious bacteria which lacks a cell wall. Extragenital infections are rare in immunocompetent adults. There are few literature reports of perinephric abscess. We present a case of non-resolving multifocal "culture-negative" abscesses in a hypogammaglobulinemic adult female due ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-020-4771-z
更新日期:2020-01-15 00:00:00
abstract:BACKGROUND:Early insights into the timing of the start, peak, and intensity of the influenza season could be useful in planning influenza prevention and control activities. To encourage development and innovation in influenza forecasting, the Centers for Disease Control and Prevention (CDC) organized a challenge to pre...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-016-1669-x
更新日期:2016-07-22 00:00:00
abstract:BACKGROUND:Seroreactivity, processes of seroconversion and seroreversion, in the context of HPV infection has been investigated in numerous studies. However, the data resulting from these studies are usually not accounted for in mathematical transmission models of various HPV types due to gaps in our understanding of t...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-13-83
更新日期:2013-02-13 00:00:00
abstract:BACKGROUND:Lack of rapid and reliable susceptibility testing for second-line drugs used in the treatment of multidrug-resistant tuberculosis (MDR-TB) may limit treatment success. METHODS:Mycobacterium tuberculosis isolates from patients referred to Kibong'oto National TB Hospital in Tanzania for second-line TB treatme...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-13-432
更新日期:2013-09-14 00:00:00
abstract:BACKGROUND:Mycobacterium goodii is a rare cause of significant infection. M. goodii has mainly been associated with lymphadenitis, cellulitis, osteomyelitis, and wound infection. CASE PRESENTATION:A case of a 76-year-old Caucasian female is presented. The patient developed a prosthetic valve endocarditis caused by M. ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-12-301
更新日期:2012-11-14 00:00:00
abstract:BACKGROUND:In order to investigate the epidemiology, molecular characteristics, and distribution of extended-spectrum β-lactamase (ESBL)- and AmpC-producing Escherichia coli from community-onset infections in Chinese county hospitals. METHODS:E. coli isolates were collected from patients with community-onset infection...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-014-0659-0
更新日期:2014-12-03 00:00:00
abstract:BACKGROUND:The new HIV treatment guidelines in China recommend antiretroviral therapy (ART) for all people living with HIV, but significant gaps in implementation still exist. Pre-exposure prophylaxis (PrEP) can effectively reduce the risk of HIV transmission among men who have sex with men (MSM). This study assessed t...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-018-3516-8
更新日期:2018-11-28 00:00:00
abstract:BACKGROUND:Giardia duodenalis is a flagellate parasite which has been considered the most common protozoa infecting human worldwide. Molecular characterization of G. duodenalis isolates have revealed the existence of eight groups (Assemblage A to H) which differ in their host distribution. Assemblages A and B are found...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-14-78
更新日期:2014-02-12 00:00:00
abstract:BACKGROUND:Tuberculosis remains a serious threat to human health as an infectious disease in China. Henan, a most populated province in China, has a high incidence of tuberculosis (TB). Though the genetic diversity of Mycobacterium tuberculosis (MTB) has been investigated in many regions, there have been only a few stu...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-018-3351-y
更新日期:2018-09-03 00:00:00
abstract:BACKGROUND:Chronic hepatitis C virus (HCV) infection can progress to cirrhosis and end-stage liver disease in a substantial proportion of patients. The infection is frequently asymptomatic, leaving many infected individuals unaware of the diagnosis until complications occur. This advocates the screening of healthy indi...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-3832-7
更新日期:2019-02-26 00:00:00
abstract:BACKGROUND:Some children are prone to recurrent invasive pneumococcal disease (rIPD) and of these, some respond insufficiently to standard pneumococcal vaccination. Little is known about how to handle these children and if they benefit from additional vaccination. Here, we present results from a nationwide study of ped...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-018-3267-6
更新日期:2018-08-06 00:00:00
abstract:BACKGROUND:Infection with cagA-positive, cagA EPIYA motif ABD type, and vacA s1, m1, and i1 genotype strains of Helicobacter pylori is associated with an exacerbated inflammatory response and increased risk of gastroduodenal diseases. However, it is unclear whether the prevalence and virulence factor genotypes found in...
journal_title:BMC infectious diseases
pub_type: 杂志文章,meta分析
doi:10.1186/1471-2334-12-223
更新日期:2012-09-21 00:00:00
abstract:BACKGROUND:Imported loiasis is a rare cause of consultation at the return of stay in central Africa, which often poses difficult diagnostic and therapeutic questions to practitioners especially those who are unaccustomed to tropical medicine. These difficulties can lead to risks for the patients especially if inappropr...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-4740-6
更新日期:2020-01-20 00:00:00
abstract:BACKGROUND:The 2009 revised World Health Organization (WHO) guidelines for dengue describe fever as the core symptom. Accordingly, the diagnosis of non-febrile patients is complicated. The aim of this study was to evaluate the importance of fever in patients with dengue according to the 2009 revised WHO classification....
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-016-2128-4
更新日期:2017-01-04 00:00:00
abstract:BACKGROUND:Monocytes are the predominant innate immune cells at the early stage of Mycobacterium tuberculosis (M. tb) infection as the host defense against intracellular pathogens. Understanding the profile of different monocyte subpopulations and the dynamics of monocyte-related biomarkers may be useful for the diagno...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-4525-y
更新日期:2019-11-28 00:00:00
abstract:BACKGROUND:Culturing has long been the gold standard for detecting aetiologic agents in bacterial infections. In some cases, however, culturing fails to detect the infection. To further investigate culture-negative samples, amplification and subsequent sequencing of the 16S rRNA gene is often applied. The aim of the pr...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-017-2333-9
更新日期:2017-03-27 00:00:00
abstract:BACKGROUND:The aim of this study was to determine the prevalence of human papillomavirus (HPV) and 15 species that cause sexually transmitted infections (STIs) in negative cytology. In addition, we compared the diagnostic performance of multiplex polymerase chain reaction (PCR) with widely available techniques used to ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-10-284
更新日期:2010-09-28 00:00:00
abstract:BACKGROUND:Surveillance of current changes in the epidemiology of Invasive Fungal Diseases (IFDs) as an important component of the antifungal stewardship programs (ASP), requires careful regular monitoring, especially in high-risk settings such as oncology centers. This study aimed to examine Candida colonization statu...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-4372-x
更新日期:2019-08-30 00:00:00
abstract:BACKGROUND:Clostridium difficile infection (CDI), a complication of antibiotic-induced injury to the gut microbiome, is a prevalent and dangerous cause of infectious diarrhea. Antimicrobial therapy for CDI is typically effective for acute symptoms, but up to one third of patients later experience recurrent CDI. Fecal-d...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-015-0930-z
更新日期:2015-04-17 00:00:00
abstract:BACKGROUND:Chemokines have been reported to play an important role in granulomatous inflammation during Schistosoma mansoni infection. However there is less information on their role in Schistosoma haematobium infection, or on the effect of concurrent HIV-1 infection, as a potential modifying influence. METHODS:To det...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-9-174
更新日期:2009-10-23 00:00:00
abstract:BACKGROUND:Bedaquiline was recently introduced into World Health Organization (WHO)-recommended regimens for treatment of drug resistant tuberculosis. There is limited data on the long-term safety of bedaquiline. Because bedaquiline prolongs the QT interval, there are concerns regarding cardiovascular safety. The Weste...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-019-4197-7
更新日期:2019-06-20 00:00:00