Abstract：
BACKGROUND:Beta-haemolytic streptococci are important contributors to the global burden of osteoarticular infections (OAI). Knowledge on the disease traits specific for streptococcal OAI, however, remains scarce. We wished to explore temporal trends of OAI caused by Group A Streptococci (GAS), Group B Streptococci (GBS) and Group C and G Streptococci (GCGS), and furthermore, to describe the associated host and pathogen characteristics. METHODS:All cases of microbiologically verified β-haemolytic streptococcal OAI in Health Region Bergen, Norway, in the period 1999-2013 were retrospectively identified. Clinical data were extracted from medical records. Microbial isolates were submitted to antibiotic susceptibility testing and molecular typing. RESULTS:A total of 24 GAS, 45 GBS and 42 GCGS acute OAI were identified. The cumulative incidence of GCGS OAI, but not GAS or GBS OAI, increased significantly from the first to the last 5-year period (IRR 5.7, p = 0.0003), with the annual incidence peaking at 1.9/100 000 in 2013. GAS OAI generally produced the most acute and severe clinical presentation, whereas GBS and GCGS predominantly affected the elderly, and were significantly associated with the presence of host risk factors of systemic and focal origin, respectively. CONCLUSIONS:We found a significantly increasing incidence of GCGS OAI, likely related to the presence of host susceptibility factors, including prosthetic material and pre-existing joint disease. With an increasing application of therapeutic and diagnostic bone and joint procedures, the rising trend of OAI caused by GCGS is likely to continue. Sustained epidemiological attentiveness to GCGS seems warranted.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
Oppegaard O,Skrede S,Mylvaganam H,Kittang BRdoi
10.1186/s12879-016-1874-7subject
Has Abstractpub_date
2016-10-04 00:00:00pages
535issue
1issn
1471-2334pii
10.1186/s12879-016-1874-7journal_volume
16pub_type
杂志文章abstract：BACKGROUND:Changes of miRNAs in exosome have been reported in different disease diagnosis and provided as potential biomarkers. In this study, we compared microRNA profile in exosomes in 5 MHFMD and 5 ESHFMD as well as in 5 healthy children. METHODS:Different expression of miRNAs in exosomes across all the three group...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-14-506
更新日期：2014-09-17 00:00:00
abstract：BACKGROUND:Granulomas caused by Mycobacterium Tuberculosis have been observed at autopsy in the heart, pre-dominantly in the myocardium and endocardium, but rarely involving the coronary vessels and valvular structures. Mycobacterium tuberculosis valvular endocarditis is extremely rare, with most reports coming from au...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-12-231
更新日期：2012-09-27 00:00:00
abstract：BACKGROUND:Identification of people living with HIV is key in HIV prevention and control. Partner Notification service is a World Health Organization backed strategy of reaching out to sexual partners of people diagnosed with HIV for HIV testing. However, its adoption and success rate in Kenya remains unknown. METHODS...
journal_title：BMC infectious diseases
pub_type： 杂志文章
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更新日期：2020-06-22 00:00:00
abstract：BACKGROUND:Comparison of antimicrobial de-escalation rates between healthcare settings is problematic. To objectively and electronically measure de-escalation a method based upon the spectrum of antimicrobial regimens administered (i.e., spectrum score) was developed. METHODS:A Delphi process was used to develop appli...
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pub_type： 杂志文章
doi：10.1186/s12879-015-0933-9
更新日期：2015-04-25 00:00:00
abstract：BACKGROUND:Human T-lymphotropic virus type 1 (HTLV-1), a retrovirus, is the causative agent of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukaemia/lymphoma (ATLL). The reported association with pulmonary disease such as bronchiectasis is less certain. METHODS:A retrospective ...
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更新日期：2015-07-06 00:00:00
abstract：BACKGROUND:Although there is a large increase in investment for tuberculosis control in Myanmar, there are few operational analyses to inform policies. Only 34% of nationally reported cases are from women. In this study, we investigate sex differences in tuberculosis diagnoses in Myanmar in order to identify potential ...
journal_title：BMC infectious diseases
pub_type： 杂志文章
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更新日期：2016-03-03 00:00:00
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pub_type： 杂志文章,多中心研究
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更新日期：2015-08-21 00:00:00
abstract：BACKGROUND:Pregnant women in malaria endemic areas are at high risk of P. falciparum infection and its complications. This study investigated the prevalence and risk factors for P. falciparum infection and malaria among pregnant women reporting for first antenatal care (ANC) clinic visit in the mount Cameroon area. ME...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-015-1211-6
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abstract：BACKGROUND:Data regarding HIV-seronegative pediatric patients with cryptococcal meningitis (CM) have been very limited. METHODS:We retrospectively reviewed non-HIV-infected in patients with CM from January 2002 through December 2013 in Beijing Children's Hospital. Records of the all patients were obtained and compared...
journal_title：BMC infectious diseases
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更新日期：2016-11-04 00:00:00
abstract：BACKGROUND:Measles is a highly infectious viral disease. In August 2017, Lyantonde District, Uganda reported a measles outbreak to Uganda Ministry of Health. We investigated the outbreak to assess the scope, factors facilitating transmission, and recommend control measures. METHODS:We defined a probable case as sudden...
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更新日期：2020-06-05 00:00:00
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更新日期：2013-12-12 00:00:00
abstract：BACKGROUND:Diagnosing pneumonia can be challenging in general practice but is essential to distinguish from other respiratory tract infections because of treatment choice and outcome prediction. We determined predictive signs, symptoms and biomarkers for the presence of pneumonia in patients with acute respiratory trac...
journal_title：BMC infectious diseases
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doi：10.1186/s12879-019-4611-1
更新日期：2019-11-20 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-015-1199-y
更新日期：2015-10-22 00:00:00
abstract：BACKGROUND:The 2009 revised World Health Organization (WHO) guidelines for dengue describe fever as the core symptom. Accordingly, the diagnosis of non-febrile patients is complicated. The aim of this study was to evaluate the importance of fever in patients with dengue according to the 2009 revised WHO classification....
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/s12879-016-2128-4
更新日期：2017-01-04 00:00:00
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journal_title：BMC infectious diseases
pub_type： 杂志文章,多中心研究
doi：10.1186/s12879-015-0765-7
更新日期：2015-02-06 00:00:00
abstract：BACKGROUND:Brucellosis is a zoonotic disease caused by brucella. It has been an increasing trend in recent years (Wang H, Xu WM, Zhu KJ, Zhu SJ, Zhang HF, Wang J, Yang Y, Shao FY, Jiang NM, Tao ZY, Jin HY, Tang Y, Huo LL, Dong F, Li ZJ, Ding H, Liu ZG, Emerg Microbes Infect 9:889-99, 2020). Brucellosis is capable to in...
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pub_type： 杂志文章
doi：10.1186/s12879-020-05358-z
更新日期：2020-09-07 00:00:00
abstract：BACKGROUND:There are few reports in the literature of invasive infection caused by Brevundimonas vesicularis in patients without immunosuppression or other predisposing factors. The choice of antimicrobial therapy for bacteremia caused by the pathogen requires more case experience to be determined. CASE PRESENTATION:T...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-6-179
更新日期：2006-12-29 00:00:00
abstract：BACKGROUND:Pneumocystis jiroveci (formerly known as P. carinii f.sp. hominis) is an opportunistic fungus that causes Pneumocystis pneumonia (PCP) in immunocompromised individuals. Pneumocystis jiroveci can be detected by polymerase chain reaction (PCR). To investigate the clinical importance of a positive Pneumocystis-...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-2-28
更新日期：2002-11-25 00:00:00
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pub_type： 杂志文章
doi：10.1186/s12879-017-2424-7
更新日期：2017-05-08 00:00:00
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doi：10.1186/1471-2334-12-354
更新日期：2012-12-17 00:00:00
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更新日期：2014-01-15 00:00:00
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更新日期：2006-03-30 00:00:00
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更新日期：2015-10-22 00:00:00
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更新日期：2012-12-23 00:00:00
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更新日期：2020-05-20 00:00:00
abstract：BACKGROUND:Infection with cagA-positive, cagA EPIYA motif ABD type, and vacA s1, m1, and i1 genotype strains of Helicobacter pylori is associated with an exacerbated inflammatory response and increased risk of gastroduodenal diseases. However, it is unclear whether the prevalence and virulence factor genotypes found in...
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pub_type： 杂志文章,meta分析
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更新日期：2012-09-21 00:00:00
abstract：BACKGROUND:Male urethritis is primary sexually transmitted. Northern Territory (NT) has the highest rates of gonococcal infection in Australia and local guidelines recommend empiric treatment with azithromycin and ceftriaxone for all men presenting with urethritis. As gonococcal drug resistance is a growing concern, th...
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更新日期：2019-11-21 00:00:00
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pub_type： 杂志文章
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更新日期：2016-11-21 00:00:00
abstract：BACKGROUND:Despite Noroviruses (NV, previously "Norwalk-like viruses") being a leading cause of acute gastroenteritis outbreaks, the impact of NV infection is at present unknown and little information is available about strains circulating in Italy. In April 2002 an outbreak of gastroenteritis occurred in the province ...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-4-37
更新日期：2004-09-21 00:00:00
abstract：BACKGROUND:Procalcitonin (PCT)-protocols to guide antibiotic treatment in severe infections are known to be effective. But less is known about the long-term effects of such protocols on antibiotic consumption under real life conditions. This retrospective study analyses the effects on antibiotic use in patients with se...
journal_title：BMC infectious diseases
pub_type： 杂志文章
doi：10.1186/1471-2334-13-158
更新日期：2013-04-01 00:00:00
