Abstract:
BACKGROUND:Male urethritis is primary sexually transmitted. Northern Territory (NT) has the highest rates of gonococcal infection in Australia and local guidelines recommend empiric treatment with azithromycin and ceftriaxone for all men presenting with urethritis. As gonococcal drug resistance is a growing concern, this study aims to improve empiric use of ceftriaxone through examining local patterns of male urethritis, comparing cases of gonococcal urethritis (GU) to controls with non-gonococcal urethritis (NGU). METHODS:A retrospective study was undertaken of all men with symptomatic urethritis presenting to Darwin sexual health clinic from July 2015 to July 2016 and aetiology of urethritis in this population was described. Demographic, risk profile, and clinical features of GU cases were compared to NGU controls. RESULTS:Among n = 145 men, the most common organisms identified were Chlamydia trachomatis (23.4%, SE 3.5%) and Neisseria gonorrhoeae (17.2%, SE 3.1%). The main predictors of GU were any abnormalities on genital examination (aOR 10.4, 95% CI 2.1 to 50.8) and a history of urethral discharge (aOR 5.7, 95% CI 1.4 to 22.6). Aboriginal patients (aOR 3.0, 95% CI 0.9 to 9.6) and those over 30 years of age (aOR 1.4, 95% CI 0.3 to 7.0) were more likely to have GU in the unadjusted analysis, but not in the adjusted model. CONCLUSION:This is the first study looking at patterns of male urethritis in urban NT and the results support a move towards adopting national guidelines to use ceftriaxone for empiric management of syndromic urethritis only in high-risk patients. In addition to traditional demographic risk factors, clinical features remain an important component of risk stratification.
journal_name
BMC Infect Disjournal_title
BMC infectious diseasesauthors
Chen W,Connor S,Gunathilake Mdoi
10.1186/s12879-019-4625-8subject
Has Abstractpub_date
2019-11-21 00:00:00pages
991issue
1issn
1471-2334pii
10.1186/s12879-019-4625-8journal_volume
19pub_type
杂志文章abstract:BACKGROUND:A novel Ehrlichia, closely related to Ehrlichia ruminantium, was recently discovered from Panola Mountain State Park, GA, USA. We conducted a study to determine if this agent was recently introduced into the United States. METHODS:We developed a sensitive PCR assay based on the conserved gltA (citrate synth...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-8-54
更新日期:2008-04-23 00:00:00
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更新日期:2015-10-14 00:00:00
abstract:BACKGROUND:The diagnosis of typhoid fever is confirmed by culture of Salmonella enterica serotype Typhi (S. typhi). However, a more rapid, simpler, and cheaper diagnostic method would be very useful especially in developing countries. The Widal test is widely used in Africa but little information exists about its relia...
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更新日期:2010-06-22 00:00:00
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更新日期:2015-07-08 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2010-09-21 00:00:00
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更新日期:2005-09-21 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,meta分析
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更新日期:2013-09-27 00:00:00
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更新日期:2019-03-15 00:00:00
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pub_type: 杂志文章,meta分析
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更新日期:2021-01-04 00:00:00
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pub_type: 杂志文章
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更新日期:2009-02-05 00:00:00
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doi:10.1186/1471-2334-11-55
更新日期:2011-03-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2013-06-19 00:00:00
abstract:BACKGROUND:Visceral disseminated varicella zoster virus (VDVZV) infection is a rare disease with a high mortality rate (55%) in immunocompromised patients, but it is not yet widely recognized in the field of nephrology. We report a case of VDVZV contracted during immunosuppressive therapy for membranous nephropathy. C...
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doi:10.1186/s12879-019-4193-y
更新日期:2019-07-15 00:00:00
abstract:BACKGROUND:To reach non-participants, reluctant to undergo clinician-based cervical cancer screening and vaginal self-sampling, urine collection for high-risk human papillomavirus detection (hrHPV) may be valuable. Using two hrHPV DNA assays, we evaluated the concordance of hrHPV positivity in urine samples in comparis...
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abstract:BACKGROUND:Human Parainfluenza Virus (hPIV) causes severe respiratory illness in infants and adults. Our study describes the association of hPIV1-4 with bronchiolitis, croup, and pneumonia using retrospective laboratory, administrative and public health data. Due to issues including the historic lack of hPIV4 in some c...
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pub_type: 杂志文章
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更新日期:2016-08-11 00:00:00
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更新日期:2010-08-11 00:00:00
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doi:10.1186/1471-2334-11-91
更新日期:2011-04-13 00:00:00
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更新日期:2010-05-25 00:00:00
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更新日期:2014-12-31 00:00:00
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pub_type: 杂志文章
doi:10.1186/s12879-019-4750-4
更新日期:2020-01-28 00:00:00
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更新日期:2009-04-22 00:00:00
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pub_type: 杂志文章
doi:10.1186/s12879-015-0768-4
更新日期:2015-02-12 00:00:00
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journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-14-103
更新日期:2014-02-25 00:00:00
abstract:BACKGROUND:Within the genus Aspergillus, A. flavus is the second most important species of clinical significance. It is predominantly associated with infections involving sinuses, eye and skin, mostly in geographic regions with hot and arid climate, including the Middle East. Recent reports on emergence of resistance t...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/1471-2334-13-126
更新日期:2013-03-06 00:00:00
abstract:BACKGROUND:Many people have multiple infections at the same time, but the combined contribution of those infections to disease-related mortality is unknown. Registered causes of death offer a unique opportunity to study associations between multiple infections. METHODS:We analysed over 900,000 death certificates that ...
journal_title:BMC infectious diseases
pub_type: 杂志文章
doi:10.1186/s12879-015-1118-2
更新日期:2015-10-06 00:00:00