Triple valve endocarditis by mycobacterium tuberculosis: a case report.

Abstract:

BACKGROUND:Granulomas caused by Mycobacterium Tuberculosis have been observed at autopsy in the heart, pre-dominantly in the myocardium and endocardium, but rarely involving the coronary vessels and valvular structures. Mycobacterium tuberculosis valvular endocarditis is extremely rare, with most reports coming from autopsy series. CASE PRESENTATION:We report the case of a 17 year old immunocompetent girl who presented with history of fever, malaise, foot gangrene and a left sided hemiparesis. On investigation she was found to have infective endocarditis involving the aortic, mitral and tricuspid valves. She had developed a right middle cerebral artery stroke. She underwent dual valve replacement and tricuspid repair. The vegetations showed granulomatous inflammation but blood cultures and other biological specimen cultures were negative for any organisms. She was started on antituberculous treatment and anticoagulation. CONCLUSION:This is the first reported case of triple valve endocarditis by Mycobacterium Tuberculosis in an immunocompetent host. Especially important is the fact that the right heart is involved which has been historically described in the setting of intravenous drug abuse.This implies that Tuberculosis should be considered in cases of culture negative endocarditis in endemic areas like Pakistan even in immunocompetent hosts.

journal_name

BMC Infect Dis

journal_title

BMC infectious diseases

authors

Shaikh Q,Mahmood F

doi

10.1186/1471-2334-12-231

subject

Has Abstract

pub_date

2012-09-27 00:00:00

pages

231

issn

1471-2334

pii

1471-2334-12-231

journal_volume

12

pub_type

杂志文章
  • Role of MIRU-VNTR and spoligotyping in assessing the genetic diversity of Mycobacterium tuberculosis in Henan Province, China.

    abstract:BACKGROUND:Tuberculosis remains a serious threat to human health as an infectious disease in China. Henan, a most populated province in China, has a high incidence of tuberculosis (TB). Though the genetic diversity of Mycobacterium tuberculosis (MTB) has been investigated in many regions, there have been only a few stu...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-018-3351-y

    authors: Shi J,Zheng D,Zhu Y,Ma X,Wang S,Li H,Xing J

    更新日期:2018-09-03 00:00:00

  • Effects of undernutrition on mortality and morbidity among adults living with HIV in sub-Saharan Africa: a systematic review and meta-analysis.

    abstract:BACKGROUND:Undernutrition is one of the most common problems among people living with HIV, contributing to premature death and the development of comorbidities within this population. In Sub-Saharan Africa (SSA), the impacts of these often inter-related conditions appear in a series of fragmented and inconclusive studi...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,meta分析

    doi:10.1186/s12879-020-05706-z

    authors: Alebel A,Demant D,Petrucka P,Sibbritt D

    更新日期:2021-01-04 00:00:00

  • The role of super-spreading events in Mycobacterium tuberculosis transmission: evidence from contact tracing.

    abstract:BACKGROUND:In current epidemiology of tuberculosis (TB), heterogeneity in infectiousness among TB patients is a challenge, which is not well studied. We aimed to quantify this heterogeneity and the presence of "super-spreading" events that can assist in designing optimal public health interventions. METHODS:TB epidemi...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-3870-1

    authors: Melsew YA,Gambhir M,Cheng AC,McBryde ES,Denholm JT,Tay EL,Trauer JM

    更新日期:2019-03-12 00:00:00

  • Amoebic liver abscess: an unusual cause for a right iliac fossa mass: a case report.

    abstract:BACKGROUND:Amoebic liver abscess is the most common extra intestinal manifestation of amoebiasis in tropical countries. It usually presents with right hypochondrial pain, fever and anorexia. Amoebic liver abscess has gained clinical significance due to the wide variety of clinical presentations which can cause diagnost...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-2093-y

    authors: Ratnasamy V,Thirunavukarasu K,Selvam K,Arumugam M

    更新日期:2016-12-08 00:00:00

  • Effect of anthelminthic treatment on helminth infection and related anaemia among school-age children in northwestern Ethiopia.

    abstract:BACKGROUND:Information about improvements in the health status of population at-risk of helminth infection after anthelminthic treatment helps to evaluate the effectiveness of the large scale deworming program. The objectives of this study were to assess the impact of anthelminthic treatment on the prevalence and inten...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-1956-6

    authors: Yimam Y,Degarege A,Erko B

    更新日期:2016-10-28 00:00:00

  • High incidence of antimicrobial resistant organisms including extended spectrum beta-lactamase producing Enterobacteriaceae and methicillin-resistant Staphylococcus aureus in nasopharyngeal and blood isolates of HIV-infected children from Cape Town, South

    abstract:BACKGROUND:There is little information on nasopharyngeal (NP) flora or bacteremia in HIV-infected children. Our aim was to describe the organisms and antimicrobial resistance patterns in children enrolled in a prospective study comparing daily and three times weekly trimethoprim-sulfamethoxazole (TMP-SMX) and isoniazid...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-8-40

    authors: Cotton MF,Wasserman E,Smit J,Whitelaw A,Zar HJ

    更新日期:2008-04-01 00:00:00

  • Plague in China 2014-All sporadic case report of pneumonic plague.

    abstract:BACKGROUND:Yersinia pestis is the pathogen of the plague and caused three pandemics worldwide. Pneumonic plague is rarer than bubonic and septicemic plague. We report detailed clinical and pathogenic data for all the three sporadic cases of pneumonic plagues in China in 2014. CASE PRESENTATION:All the three patients a...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-1403-8

    authors: Li YF,Li DB,Shao HS,Li HJ,Han YD

    更新日期:2016-02-19 00:00:00

  • The predicted impact of tuberculosis preventive therapy: the importance of disease progression assumptions.

    abstract:BACKGROUND:Following infection with Mycobacterium tuberculosis (M.tb), individuals may rapidly develop tuberculosis (TB) disease or enter a "latent" infection state with a low risk of progression to disease. Mathematical models use a variety of structures and parameterisations to represent this process. The effect of t...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-05592-5

    authors: Sumner T,White RG

    更新日期:2020-11-23 00:00:00

  • Predominant porB1A and porB1B genotypes and correlation of gene mutations with drug resistance in Neisseria gonorrhoeae isolates in Eastern China.

    abstract:BACKGROUND:Variations of porB1A and porB1B genes and their serotypes exist in Neisseria gonorrhoeae isolates from different geographical areas, and some site mutations in the porB1B gene correlate with drug resistance. METHODS:The β-lactamase production of N. gonorrhoeae isolates was determined by paper acidometric te...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-10-323

    authors: Sun A,Fan X,Gu Y,Du P,Tang R,Mao Y,Lin X,Yan J

    更新日期:2010-11-10 00:00:00

  • Treatment of isoniazid-resistant pulmonary tuberculosis.

    abstract:BACKGROUND:Although resistance to isoniazid (INH) is the most common form of drug resistance seen among Mycobacterium tuberculosis isolates, there have been few studies on the efficacy and optimal duration of treatment for patients with INH-resistant tuberculosis (TB). METHODS:We evaluated retrospectively the treatmen...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-8-6

    authors: Kim YH,Suh GY,Chung MP,Kim H,Kwon OJ,Lim SY,Lim SY,Koh WJ

    更新日期:2008-01-23 00:00:00

  • Moderate endurance training (marathon-training) - effects on immunologic and metabolic parameters in HIV-infected patients: the 42 KM cologne project.

    abstract:BACKGROUND:Improved treatment options of HIV have resulted in regular physical activities of many HIV-infected patients. However, data on effects of sports in HIV-patients are scarce. METHODS:21 HIV-infected persons were monitored prospectively while preparing for a marathon run. Multiple parameters with regard to imm...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-017-2651-y

    authors: Schlabe S,Vogel M,Boesecke C,Schwarze-Zander C,Rockstroh JK,Körner C,Brixius K,Wasmuth JC

    更新日期:2017-08-08 00:00:00

  • Population-level effects of clinical immunity to malaria.

    abstract:BACKGROUND:Despite a resurgence in control efforts, malaria remains a serious public-health problem, causing millions of deaths each year. One factor that complicates malaria-control efforts is clinical immunity, the acquired immune response that protects individuals from symptoms despite the presence of parasites. Cli...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-13-428

    authors: Keegan LT,Dushoff J

    更新日期:2013-09-11 00:00:00

  • Determination of clinical and demographic predictors of laboratory-confirmed influenza with subtype analysis.

    abstract:BACKGROUND:Rapid influenza diagnosis is important for early identification of outbreaks, effective management of high-risk contacts, appropriate antiviral use, decreased inappropriate antibiotic use and avoidance of unnecessary laboratory testing. Given the inconsistent performance of many rapid influenza tests, clinic...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-12-129

    authors: Woolpert T,Brodine S,Lemus H,Waalen J,Blair P,Faix D

    更新日期:2012-06-07 00:00:00

  • Lemierre's syndrome and genetic polymorphisms: a case report.

    abstract:BACKGROUND:Lemierre's syndrome presents a classic clinical picture, the pathophysiology of which remains obscure. Attempts have been made to trace genetic predispositions that modify the host detection of pathogen or the resultant systemic reaction. CASE PRESENTATION:A 17-year old female, with no previous medical hist...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-6-115

    authors: Constantin JM,Mira JP,Guerin R,Cayot-Constantin S,Lesens O,Gourdon F,Romaszko JP,Linval P,Laurichesse H,Bazin JE

    更新日期:2006-07-17 00:00:00

  • Knowledge, attitudes and behaviour of hospital health-care workers regarding influenza A/H1N1: a cross sectional survey.

    abstract:BACKGROUND:To assess the knowledge, the attitudes, and the behaviour towards influenza A/H1N1 and the vaccination among health-care workers (HCWs). METHODS:A sample of HCWs was selected from a random sample of non-teaching public hospitals, located in the cities of Naples and Avellino (Italy), received a self-administ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-14-208

    authors: Albano L,Matuozzo A,Marinelli P,Di Giuseppe G

    更新日期:2014-04-16 00:00:00

  • Impact of daily versus weekly service of infectious diseases consultation on hospital antimicrobial consumption: a retrospective study.

    abstract:BACKGROUND:To verify whether a daily service of Infectious Diseases consultation (ID-cons) is more effective than a weekly service in reducing antibiotic (ATB) consumption without worsening of clinical outcomes. METHODS:Two-year observational analysis of the ID-cons provided in a hospital setting in Milan, Italy. ID-c...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-05550-1

    authors: Cona A,Gazzola L,Viganò O,Bini T,Marchetti GC,d'Arminio Monforte A

    更新日期:2020-11-07 00:00:00

  • Outbreak of Middle East respiratory syndrome coronavirus in Saudi Arabia: a retrospective study.

    abstract:BACKGROUND:The Middle East respiratory syndrome (MERS) is proposed to be a zoonotic disease. Dromedary camels have been implicated due to reports that some confirmed cases were exposed to camels. Risk factors for MERS coronavirus (MERS-CoV) infections in humans are incompletely understood. This study aimed to describe ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-2137-3

    authors: Aleanizy FS,Mohmed N,Alqahtani FY,El Hadi Mohamed RA

    更新日期:2017-01-05 00:00:00

  • Detecting SARS-CoV-2 at point of care: preliminary data comparing loop-mediated isothermal amplification (LAMP) to polymerase chain reaction (PCR).

    abstract:BACKGROUND:A cost effective and efficient diagnostic tool for COVID-19 as near to the point of care (PoC) as possible would be a game changer in the current pandemic. We tested reverse transcription loop mediated isothermal amplification (RT-LAMP), a method which can produce results in under 30 min, alongside standard ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-05484-8

    authors: Österdahl MF,Lee KA,Lochlainn MN,Wilson S,Douthwaite S,Horsfall R,Sheedy A,Goldenberg SD,Stanley CJ,Spector TD,Steves CJ

    更新日期:2020-10-20 00:00:00

  • Vaccination with Toxoplasma gondii calcium-dependent protein kinase 6 and rhoptry protein 18 encapsulated in poly(lactide-co-glycolide) microspheres induces long-term protective immunity in mice.

    abstract:BACKGROUND:Toxoplasmosis is a worldwide zoonosis caused by the intracellular parasite Toxoplasma gondii. However, no effective vaccine is yet available. Poly(lactide-co-glycolide) polymers can reduce protein degradation and sustain the release of antigens over a long period, which could generate a long-lasting immune r...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-016-1496-0

    authors: Zhang NZ,Xu Y,Wang M,Chen J,Huang SY,Gao Q,Zhu XQ

    更新日期:2016-04-18 00:00:00

  • Description and validation of a spectrum score method to measure antimicrobial de-escalation in healthcare associated pneumonia from electronic medical records data.

    abstract:BACKGROUND:Comparison of antimicrobial de-escalation rates between healthcare settings is problematic. To objectively and electronically measure de-escalation a method based upon the spectrum of antimicrobial regimens administered (i.e., spectrum score) was developed. METHODS:A Delphi process was used to develop appli...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-015-0933-9

    authors: Madaras-Kelly K,Jones M,Remington R,Caplinger C,Huttner B,Samore M

    更新日期:2015-04-25 00:00:00

  • A novel optical biosensor for the early diagnosis of sepsis and severe Covid-19: the PROUD study.

    abstract:BACKGROUND:The accuracy of a new optical biosensor (OB) point-of-care device for the detection of severe infections is studied. METHODS:The OB emits different wavelengths and outputs information associated with heart rate, pulse oximetry, levels of nitric oxide and kidney function. At the first phase, recordings were ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-05607-1

    authors: Doulou S,Leventogiannis K,Tsilika M,Rodencal M,Katrini K,Antonakos N,Kyprianou M,Karofylakis E,Karageorgos A,Koufargyris P,Christopoulos G,Kassianidis G,Stamatelopoulos K,Newberry R,Giamarellos-Bourboulis EJ

    更新日期:2020-11-19 00:00:00

  • An enhanced regimen as post-exposure chemoprophylaxis for leprosy: PEP+.

    abstract::The ongoing transmission of Mycobacterium (M.) leprae reflected in a very slow decline in leprosy incidence, forces us to be innovative and conduct cutting-edge research. Single dose rifampicin (SDR) as post-exposure prophylaxis (PEP) for contacts of leprosy patients, reduces their risk to develop leprosy by 60%. This...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-018-3402-4

    authors: Mieras LF,Taal AT,van Brakel WH,Cambau E,Saunderson PR,Smith WCS,Prakoeswa CRS,Astari L,Scollard DM,do Nascimento DC,Grosset J,Kar HK,Izumi S,Gillini L,Virmond MCL,Sturkenboom MGG

    更新日期:2018-10-05 00:00:00

  • Epidemic characteristics of hemorrhagic fever with renal syndrome in China, 2006-2012.

    abstract:BACKGROUND:Hemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses is a serious public health problem in China. The National Notifiable Disease Surveillance System (NNDSS) was established online by China CDC in 2004 and rodent surveillance sites were adjusted to 40 sites in 22 provinces in 2005. Here we ana...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-14-384

    authors: Zhang S,Wang S,Yin W,Liang M,Li J,Zhang Q,Feng Z,Li D

    更新日期:2014-07-11 00:00:00

  • A cluster randomized trial for the implementation of an antibiotic checklist based on validated quality indicators: the AB-checklist.

    abstract:BACKGROUND:Recently we developed and validated generic quality indicators that define 'appropriate antibiotic use' in hospitalized adults treated for a (suspected) bacterial infection. Previous studies have shown that with appropriate antibiotic use a reduction of 13% of length of hospital stay can be achieved. Our mai...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12879-015-0867-2

    authors: van Daalen FV,Prins JM,Opmeer BC,Boermeester MA,Visser CE,van Hest RM,Hulscher ME,Geerlings SE

    更新日期:2015-03-19 00:00:00

  • Prevalence and associated factors of scabies in Ethiopia: systematic review and Meta-analysis.

    abstract:BACKGROUND:Scabies is an infectious disease that affects the skin caused by the mite Sarcoptes scabiei and it transmitted through close personal contact. Even though it is easily treatable disease, its prevalence is high and continuous as neglected tropical disease of resource-poor settings, and particularly affects yo...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章,meta分析

    doi:10.1186/s12879-020-05106-3

    authors: Azene AG,Aragaw AM,Wassie GT

    更新日期:2020-05-27 00:00:00

  • Methicillin-resistant Staphylococcus aureus nasal colonization among HIV-infected patients in Taiwan: prevalence, molecular characteristics and associated factors with nasal carriage.

    abstract:BACKGROUND:To evaluate nasal carriage, antibiotic susceptibility and molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA), as well as the risk factors of MRSA colonization, in human immunodeficiency virus (HIV)-infected patients in northern Taiwan. METHODS:From September 2014 to November 201...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-04979-8

    authors: Hsu YY,Wu D,Hung CC,Huang SS,Yuan FH,Lee MH,Huang CT,Shie SS,Huang PY,Yang CC,Cheng CW,Leu HS,Wu TS,Huang YC

    更新日期:2020-03-30 00:00:00

  • Modelling the force of infection for hepatitis B and hepatitis C in injecting drug users in England and Wales.

    abstract:BACKGROUND:Injecting drug use is a key risk factor, for several infections of public health importance, especially hepatitis B (HBV) and hepatitis C (HCV). In England and Wales, where less than 1% of the population are likely to be injecting drug users (IDUs), approximately 38% of laboratory reports of HBV, and 95% of ...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-6-93

    authors: Sutton AJ,Gay NJ,Edmunds WJ,Hope VD,Gill ON,Hickman M

    更新日期:2006-06-08 00:00:00

  • Epidemiology of urinary tract infection and antimicrobial resistance in a pediatric hospital in Nepal.

    abstract:BACKGROUND:Urinary tract infection is an infection affecting infants and children. The aim of this study was to determine the etiology of urinary tract infection along with their antimicrobial resistance. METHODS:This cross-sectional study was conducted from June 2015 to January 2016 at Siddhi Memorial Hospital, Bhakt...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-019-3997-0

    authors: Ganesh R,Shrestha D,Bhattachan B,Rai G

    更新日期:2019-05-14 00:00:00

  • The influence of carbapenem resistance on mortality in solid organ transplant recipients with Acinetobacter baumannii infection.

    abstract:BACKGROUND:Infection with carbapenem-resistant Acinetobacter baumannii has been associated with high morbidity and mortality in solid organ transplant recipients. The main objective of this study was to assess the influence of carbapenem resistance and other potential risk factors on the outcome of A. baumannii infecti...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/1471-2334-12-351

    authors: de Gouvêa EF,Martins IS,Halpern M,Ferreira AL,Basto ST,Gonçalves RT,Moreira BM,Santoro-Lopes G

    更新日期:2012-12-13 00:00:00

  • Continuous renal replacement therapy rescues severe haemorrhagic fever with renal syndrome in pregnancy: a case report.

    abstract:BACKGROUND:Haemorrhagic fever with renal syndrome (HFRS) is a natural epidemic disease caused by various types of viruses of the genus Hantavirus, which are mainly transmitted by contact with the infected rodents and their droppings. Pregnancy complicated with HFRS is rare; however, adverse maternal and foetal outcomes...

    journal_title:BMC infectious diseases

    pub_type: 杂志文章

    doi:10.1186/s12879-020-05638-8

    authors: Ying X,Lai X,Jin X,Cai L,Li X

    更新日期:2020-12-03 00:00:00