One-layer versus two-layer duct-to-mucosa pancreaticojejunostomy after pancreaticoduodenectomy: study protocol for a randomized controlled trial.

abstract：BACKGROUND:Metabolic acidosis is more common with advancing chronic kidney disease, and has been associated with impaired physical function, impaired bone health, accelerated decline in kidney function and increased vascular risk. Although oral sodium bicarbonate is widely used to correct metabolic acidosis, there exis...

journal_title：Trials

authors： Witham MD,Band MM,Littleford RC,Avenell A,Soiza RL,McMurdo ME,Sumukadas D,Ogston SA,Lamb EJ,Hampson G,McNamee P,BiCARB Study Group.

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:UK National Institute of Health and Clinical Excellence guidelines for obsessive compulsive disorder (OCD) specify recommendations for the treatment and management of OCD using a stepped care approach. Steps three to six of this model recommend treatment options for people with OCD that range from low-intens...

journal_title：Trials

authors： Gellatly J,Bower P,McMillan D,Roberts C,Byford S,Bee P,Gilbody S,Arundel C,Hardy G,Barkham M,Reynolds S,Gega L,Mottram P,Lidbetter N,Pedley R,Peckham E,Connell J,Molle J,O'Leary N,Lovell K

更新日期：2014-07-10 00:00:00

abstract：BACKGROUND:Hypertension is a risk factor for cardiovascular disease, and the prevalence of hypertension tends to increase with age. Current treatments for hypertension have side effects and poor adherence. Qigong has been studied as an alternative therapy for hypertension; however, the types of qigong used in those stu...

journal_title：Trials

authors： Park JE,Liu Y,Park T,Hong S,Kim JE,Kim TH,Kim AR,Jung SY,Park H,Choi SM

更新日期：2011-11-21 00:00:00

abstract：BACKGROUND:Trials of complex interventions are associated with high costs and burdens in terms of paperwork, management, data collection, validation, and intervention fidelity assessment occurring across multiple sites. Traditional data collection methods rely on paper-based forms, where processing can be time-consumin...

journal_title：Trials

authors： Drew CJ,Poile V,Trubey R,Watson G,Kelson M,Townson J,Rosser A,Hood K,Quinn L,Busse M

更新日期：2016-11-17 00:00:00

abstract：BACKGROUND:Worldwide, prevalence rates of adolescent non-suicidal self-injury (NSSI) range between 13 and 45%. In Germany, lifetime prevalence of NSSI is around 25% in non-clinical samples, and the one-year prevalence for repetitive NSSI is 4%. NSSI is present in the context of several axis I and II disorders (for exam...

journal_title：Trials

authors： Fischer G,Brunner R,Parzer P,Resch F,Kaess M

更新日期：2013-09-13 00:00:00

abstract：BACKGROUND:This update outlines changes to the MObile Technology for Improved Family Planning study statistical analysis plan and plans for long-term follow-up. These changes result from obtaining additional funding and the decision to restrict the primary analysis to participants with available follow-up data. The cha...

journal_title：Trials

authors： Smith C,Ngo TD,Edwards P,Free C

更新日期：2014-11-12 00:00:00

abstract：BACKGROUND:ICU stay is often associated with negative experiences for the individual patient. Many patients are disabled and their communication is restricted during the ICU stay. Specific information on procedures, sensations and coping behavior are thought to reduce anxiety on the ICU. Until now information programs ...

journal_title：Trials

authors： Fleischer S,Berg A,Neubert TR,Koller M,Behrens J,Becker R,Horbach A,Radke J,Rothmund M,Kuss O

更新日期：2009-09-14 00:00:00

abstract：BACKGROUND:To evaluate the antiplaque effects of an alcohol-free mouthrinse containing essential oils-Listerine Zero (LZ)-and an alcohol-based essential oils mouthrinse (EO+) compared with a positive control of 0.20% chlorhexidine mouthrinse (CHX) and a negative control of a placebo solution (saline), using an in vivo ...

journal_title：Trials

authors： Marchetti E,Tecco S,Caterini E,Casalena F,Quinzi V,Mattei A,Marzo G

更新日期：2017-03-31 00:00:00

abstract：BACKGROUND:Increasingly, genomics is informing clinical practice, but challenges remain for medical professionals lacking genetics expertise, and in access to and clinical utility of genomic testing for minority and underrepresented populations. The latter is a particularly pernicious problem due to the historical lack...

journal_title：Trials

authors： Odgis JA,Gallagher KM,Suckiel SA,Donohue KE,Ramos MA,Kelly NR,Bertier G,Blackburn C,Brown K,Fielding L,Lopez J,Aguiniga KL,Maria E,Rodriguez JE,Sebastin M,Teitelman N,Watnick D,Yelton NM,Abhyankar A,Abul-Husn NS,B

更新日期：2021-01-14 00:00:00

abstract：BACKGROUND:Indigenous Australian youth (aged 15 to 34) have up to four times the risk of suicide compared with their non-Indigenous counterparts. Barriers to help-seeking include shame, feared loss of autonomy and negative attitudes towards healthcare providers. The use of mobile devices and apps continues to rise amon...

journal_title：Trials

authors： Shand FL,Ridani R,Tighe J,Christensen H

更新日期：2013-11-20 00:00:00

abstract：BACKGROUND:The effects of restrictive fluid therapy combined with controlled hypotension in the elderly on systemic oxygen metabolism and renal function are clinical concerns. The aim of this study was to evaluate blood loss, oxygen metabolism, and renal function in different levels of controlled hypotension induced by...

journal_title：Trials

authors： Qiu X,Tan Z,Tang W,Ye H,Lu X

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND:Parkinson's Disease is a degenerative neurological condition that causes movement problems and other distressing symptoms. People with Parkinson's disease gradually lose their independence and strain is placed on family members. A multidisciplinary approach to rehabilitation for people with Parkinson's is re...

journal_title：Trials

authors： Gage H,Ting S,Williams P,Bryan K,Kaye J,Castleton B,Trend P,Wade D

更新日期：2011-11-23 00:00:00

abstract：:There are many acknowledged benefits for the reuse of clinical trial data; from independent verification of published results to the evaluation of new hypotheses. However, the reuse of shared clinical trial data is not without obstacles. Here we present some of the issues and lessons learned from our own experiences i...

journal_title：Trials

authors： Wilkinson T,Sinha S,Peek N,Geifman N

更新日期：2019-08-19 00:00:00

abstract：BACKGROUND:Neurofeedback has been applied effectively in various areas, especially in the treatment of children with attention-deficit/hyperactivity disorder (ADHD). This study protocol is designed to investigate the effect of slow cortical potential (SCP) feedback and a new form of neurofeedback using near-infrared sp...

journal_title：Trials

authors： Mayer K,Wyckoff SN,Fallgatter AJ,Ehlis AC,Strehl U

更新日期：2015-04-18 00:00:00

abstract：BACKGROUND:Pancreatic ductal adenocarcinoma (PDA) is one of the most aggressive malignancies with marked resistance to chemo- and radiotherapy. PDA-cancer stem cells (CSCs) are not targeted by current therapies and may be a reason for poor prognosis. Studies indicate that diets rich in cabbage, broccoli, and cauliflowe...

journal_title：Trials

authors： Lozanovski VJ,Houben P,Hinz U,Hackert T,Herr I,Schemmer P

更新日期：2014-06-03 00:00:00

abstract：:Mental health problems are highly prevalent in children and adolescents, but professional help-seeking behavior in this age group is extremely low. Therefore, the ProHEAD ("Promoting Help-seeking using E-technology for Adolescents") consortium focuses on three main objectives, i.e.: (1) improving young people's help-s...

journal_title：Trials

authors： Kaess M,Bauer S

更新日期：2019-01-22 00:00:00

abstract：BACKGROUND:The Pneumatic CompREssion for Preventing VENous Thromboembolism (PREVENT) trial evaluates the effect of adjunctive intermittent pneumatic compression (IPC) with pharmacologic thromboprophylaxis compared to pharmacologic thromboprophylaxis alone on venous thromboembolism (VTE) in critically ill adults. METHO...

journal_title：Trials

authors： Arabi Y,Al-Hameed F,Burns KEA,Mehta S,Alsolamy S,Almaani M,Mandourah Y,Almekhlafi GA,Al Bshabshe A,Finfer S,Alshahrani M,Khalid I,Mehta Y,Gaur A,Hawa H,Buscher H,Arshad Z,Lababidi H,Al Aithan A,Jose J,Abdukahil SA

更新日期：2018-03-15 00:00:00

abstract：BACKGROUND:The cross-sectional area of the subclavian vein (csSCV) is an important factor determining the success rate of SCV catheterization. The head-down position increases the csSCV. However, the effects of lateral tilting on subclavian venous cross-sectional area have not yet been explored. In this trial, we test ...

journal_title：Trials

authors： Jung DE,Lee HC,Yoon HK,Park HP

更新日期：2018-05-24 00:00:00

abstract：BACKGROUND:Several drugs are being repurposed for the treatment of the coronavirus disease 2019 (COVID-19) pandemic based on in vitro or early clinical findings. As these drugs are being used in varied regimens and dosages, it is important to enable synthesis of existing safety data from clinical trials. However, avail...

journal_title：Trials

authors： Rodgers F,Pepperrell T,Keestra S,Pilkington V

更新日期：2021-01-15 00:00:00

abstract：BACKGROUND:Adolescence is a high-risk time for the development of mental health and substance use problems. However, fewer than one in four 16-24 year-olds with a current disorder access health services, with those experiencing a substance use disorder being the least likely to seek professional help. Research indicate...

journal_title：Trials

authors： Lubman DI,Berridge BJ,Blee F,Jorm AF,Wilson CJ,Allen NB,McKay-Brown L,Proimos J,Cheetham A,Wolfe R

更新日期：2016-08-08 00:00:00

abstract：BACKGROUND:Chronic non-specific low back pain is the most common medical problem for which patients seek complementary and alternative medical treatment, including bee venom acupuncture. However, the effectiveness and safety of such treatments have not been fully established by randomized clinical trials. The aim of th...

journal_title：Trials

authors： Seo BK,Lee JH,Sung WS,Song EM,Jo DJ

更新日期：2013-01-14 00:00:00

abstract：BACKGROUND:Gestational diabetes (GDM) is associated with an increased lifetime risk for the development of glucose abnormalities, metabolic syndrome, cardiovascular disease, depression and tumours. Despite this high risk of additional comorbidities, there is no standardised approach to the long-term follow-up of women ...

journal_title：Trials

authors： Bogdanet D,Egan A,Fhelelboom N,Biesty L,Thangaratinam S,Dempsey E,Crowther C,Devane D,Dunne F

更新日期：2019-01-05 00:00:00

abstract：BACKGROUND:Allergic rhinitis is a chronic illness, affecting 10 to 40% of the worldwide population. Chinese herbal medicines, the treatment of allergic rhinitis, adopted thousands of years in ancient China, has recently raised much attention among researchers globally. This study evaluates the effects of two Chinese he...

journal_title：Trials

authors： Chan RY,Chien WT

更新日期：2014-07-02 00:00:00

abstract：BACKGROUND:Classroom-based stuttering intervention addressing negative peer attitudes, perceptions, teasing and bullying of children who stutter (CWS) is required as part of holistic stuttering management because of its occurrence in primary school. This study was conducted in 2017, in 10 primary schools in the Western...

journal_title：Trials

authors： Mallick R,Kathard H,Borhan ASM,Pillay M,Thabane L

更新日期：2018-11-29 00:00:00

abstract：BACKGROUND:Cancer is one of the major health issues worldwide. An increasing number of cancer patients are offered treatment with surgery, chemotherapy and radiotherapy. Traditional Chinese medicine (TCM) is one of the most common complementary therapies offered to cancer patients in Taiwan. We designed a randomized, d...

journal_title：Trials

authors： Lo LC,Chen CY,Chen ST,Chen HC,Lee TC,Chang CS

更新日期：2012-12-03 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated the benefit of early integration of palliative care (PC) in oncology. However, patients continue to receive late referrals to PC even in comprehensive cancer centers. Patients and health professionals may perceive PC as 'a place to die,' and this stigma is a barrier to time...

journal_title：Trials

authors： do Carmo TM,Paiva BS,de Siqueira MR,da Rosa Lde T,de Oliveira CZ,Nascimento MS,Paiva CE

更新日期：2015-04-12 00:00:00

abstract：INTRODUCTION:Psoriasis vulgaris is a common skin disease characterized by persistent localized erythematous scaly plaques, typically on the elbows, knees, and scalp. It is an immune-abnormal disease that progresses slowly over a long period with frequent symptom recurrence. Current studies have shown that acupuncture i...

journal_title：Trials

authors： Deng J,Lu C,Xiang Y,Deng H,Wen Z,Yao D,Xuan M,Yan Y

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:As people live longer, their risk of disability increases. Disability affects quality of life and increases health and social care costs. Preventing or delaying disability is therefore an important objective, and identifying an effective intervention could improve the lives of many older people. Observationa...

journal_title：Trials

authors： Morgan GS,Haase AM,Campbell R,Ben-Shlomo Y

更新日期：2015-03-13 00:00:00

abstract：BACKGROUND:There is considerable evidence showing that injured people who are involved in a compensation process show poorer physical and mental recovery than those with similar injuries who are not involved in a compensation process. One explanation for this reduced recovery is that the legal process and the associate...

journal_title：Trials

authors： Elbers NA,Akkermans AJ,Cuijpers P,Bruinvels DJ

更新日期：2013-07-20 00:00:00

abstract：BACKGROUND:Disinvestment from inefficient or ineffective health services is a growing priority for health care systems. Provision of allied health services over the weekend is now commonplace despite a relative paucity of evidence supporting their provision. The relatively high cost of providing this service combined w...

journal_title：Trials

authors： Haines TP,O'Brien L,Mitchell D,Bowles KA,Haas R,Markham D,Plumb S,Chiu T,May K,Philip K,Lescai D,McDermott F,Sarkies M,Ghaly M,Shaw L,Juj G,Skinner EH

更新日期：2015-04-02 00:00:00