Short-term psychotherapeutic treatment in adolescents engaging in non-suicidal self-injury: a randomized controlled trial.

abstract：BACKGROUND:The obesity epidemic is well established, particularly in rural settings. Programs promoting healthy lifestyles for rural women are urgently needed; however, participant engagement is challenging. In the context of a large randomized controlled trial targeting the prevention of weight gain in rural women, we...

journal_title：Trials

authors： Kozica SL,Harrison CL,Teede HJ,Ng S,Moran LJ,Lombard CB

更新日期：2015-09-16 00:00:00

abstract：BACKGROUND:Previous interventions to increase physical activity and reduce cardiovascular risk factors have been targeted at individuals with established disease; less attention has been given to intervention among individuals with high risk for disease nor has there been determination of the influence of setting in wh...

journal_title：Trials

authors： Petrella RJ,Aizawa K,Shoemaker K,Overend T,Piche L,Marin M,Shapiro S,Atkin S

更新日期：2011-02-16 00:00:00

abstract：BACKGROUND:Graves' hyperthyroidism is an autoimmune disease causing hyperfunction of the thyroid gland. The concentration of selenium is high in the thyroid gland and two important groups of enzymes within the thyroid are selenoproteins, that is, they depend on selenium. Selenium may have beneficial effects on autoimmu...

journal_title：Trials

authors： Watt T,Cramon P,Bjorner JB,Bonnema SJ,Feldt-Rasmussen U,Gluud C,Gram J,Hansen JL,Hegedüs L,Knudsen N,Bach-Mortensen P,Nolsøe R,Nygaard B,Pociot F,Skoog M,Winkel P,Rasmussen AK

更新日期：2013-04-30 00:00:00

abstract：BACKGROUND:Postoperative knee swelling is common and impairs early postoperative function following total knee arthroplasty. It was hypothesised that the use of a short-stretch, inelastic compression bandage would reduce knee swelling and improve pain and early function. The aim of this study was to provide preliminary...

journal_title：Trials

authors： Brock TM,Sprowson AP,Muller S,Reed MR

更新日期：2017-01-09 00:00:00

abstract：BACKGROUND:Adolescent depression is a common mental health problem and there is an urgent need for effective and accessible treatments. Internet-based interventions solve many obstacles for seeking and receiving treatment, thus increasing access to effective treatments. Internet-based cognitive behavioural therapy (ICB...

journal_title：Trials

authors： Mechler J,Lindqvist K,Carlbring P,Lilliengren P,Falkenström F,Andersson G,Topooco N,Johansson R,Midgley N,Edbrooke-Childs J,J Dahl HS,Sandell R,Thorén A,Ulberg R,Lindert Bergsten K,Philips B

更新日期：2020-06-29 00:00:00

abstract：BACKGROUND:Mobile health (mHealth) presents one of the potential solutions to maximize health worker impact and efficiency in an effort to reach the Sustainable Development Goals 3.1 and 3.2, particularly in sub-Saharan African countries. Poor-quality clinical decision-making is known to be associated with poor pregnan...

journal_title：Trials

authors： Amoakoh HB,Klipstein-Grobusch K,Amoakoh-Coleman M,Agyepong IA,Kayode GA,Sarpong C,Grobbee DE,Ansah EK

更新日期：2017-04-04 00:00:00

abstract：BACKGROUND:Randomised controlled trials are being increasingly used to evaluate new surgical interventions. There are a number of problematic methodological issues specific to surgical trials, the most important being identifying whether patients are eligible for recruitment into the trial. This is in part due to the d...

journal_title：Trials

authors： Parsons NR,Kulikov Y,Girling A,Griffin D

更新日期：2011-12-13 00:00:00

abstract：BACKGROUND:With a survival rate of 6 to 11%, out-of-hospital cardiac arrest (OHCA) remains a healthcare challenge with room for improvement in morbidity and mortality. The guidelines emphasize the highest possible quality of cardiopulmonary resuscitation (CPR) and chest compressions (CC). It is essential to minimize CC...

journal_title：Trials

authors： Buléon C,Parienti JJ,Morilland-Lecoq E,Halbout L,Cesaréo E,Dubien PY,Jardel B,Boyer C,Husson K,Andriamirado F,Benet X,Morel-Marechal E,Aubrion A,Muntean C,Dupire E,Roupie E,Hubert H,Vilhelm C,Gueugniaud PY,CILICA-HS

更新日期：2020-07-08 00:00:00

abstract：BACKGROUND:Poverty undermines adherence to tuberculosis treatment. Economic support may both encourage and enable patients to complete treatment. In South Africa, which carries a high burden of tuberculosis, such support may improve the currently poor outcomes of patients on tuberculosis treatment. The aim of this stud...

journal_title：Trials

authors： Lutge E,Lewin S,Volmink J,Friedman I,Lombard C

更新日期：2013-05-28 00:00:00

abstract：BACKGROUND:To prevent clinical relapse in teenagers with inflammatory bowel disease (IBD) there is a need to monitor disease activity continuously. Timely optimisation of medical treatment may nip a preclinical relapse in the bud and change the natural course of IBD. Traditionally, disease monitoring is done during sch...

journal_title：Trials

authors： Heida A,Dijkstra A,Groen H,Muller Kobold A,Verkade H,van Rheenen P

更新日期：2015-06-16 00:00:00

abstract：BACKGROUND:In the presence of heterogeneous treatment effects, it is desirable to divide patients into subgroups based on their expected response to treatment. This is formalised via a personalised treatment recommendation: an algorithm that uses biomarker measurements to select treatments. It could be that multiple, r...

journal_title：Trials

authors： Pierce M,Emsley R

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:There is evidence to suggest that delivery of diabetes self-management support by diabetes educators in primary care may improve patient care processes and patient clinical outcomes; however, the evaluation of such a model in primary care is nonexistent in Canada. This article describes the design for the ev...

journal_title：Trials

authors： Gucciardi E,Fortugno M,Horodezny S,Lou W,Sidani S,Espin S,Webster F,Shah BR

更新日期：2012-09-13 00:00:00

abstract：BACKGROUND:In the last few years, excessive internet use and computer gaming have increased dramatically. Salience, mood modification, tolerance, withdrawal symptoms, conflict, and relapse have been defined as diagnostic criteria for internet addiction (IA) and computer addiction (CA) in the scientific community. Despi...

journal_title：Trials

authors： Jäger S,Müller KW,Ruckes C,Wittig T,Batra A,Musalek M,Mann K,Wölfling K,Beutel ME

更新日期：2012-04-27 00:00:00

abstract：BACKGROUND:Biomass fuel smoke is a leading risk factor for the burden of disease worldwide. International campaigns are promoting the widespread adoption of liquefied petroleum gas (LPG) in resource-limited settings. However, it is unclear if the introduction and use of LPG stoves, in settings where biomass fuels are u...

journal_title：Trials

authors： Fandiño-Del-Rio M,Goodman D,Kephart JL,Miele CH,Williams KN,Moazzami M,Fung EC,Koehler K,Davila-Roman VG,Lee KA,Nangia S,Harvey SA,Steenland K,Gonzales GF,Checkley W,Cardiopulmonary outcomes and Household Air Pollution tria

更新日期：2017-11-03 00:00:00

abstract：BACKGROUND:For adults surviving stroke due to spontaneous (non-traumatic) intracerebral haemorrhage (ICH) who had taken an antithrombotic (i.e. anticoagulant or antiplatelet) drug for the prevention of vaso-occlusive disease before the ICH, it is unclear whether starting antiplatelet drugs results in an increase in the...

journal_title：Trials

authors： Al-Shahi Salman R,Dennis MS,Murray GD,Innes K,Drever J,Dinsmore L,Williams C,White PM,Whiteley WN,Sandercock PAG,Sudlow CLM,Newby DE,Sprigg N,Werring DJ,RESTART collaborators.

更新日期：2018-03-05 00:00:00

abstract：BACKGROUND:Obesity affects 25% of the UK adult population but modest weight loss can reduce the incidence of obesity-related chronic disease. Some effective weight loss treatments exist but there is no nationally available National Health Service (NHS) treatment service, and general practitioners (GPs) rarely discuss w...

journal_title：Trials

authors： Lewis A,Jolly K,Adab P,Daley A,Farley A,Jebb S,Lycett D,Clarke S,Christian A,Jin J,Thompson B,Aveyard P

更新日期：2013-11-19 00:00:00

abstract：BACKGROUND:Quality and service improvement (QSI) research employs a broad range of methods to enhance the efficiency of healthcare delivery. QSI research differs from traditional healthcare research and poses unique ethical questions. Since QSI research aims to generate knowledge to enhance quality improvement efforts,...

journal_title：Trials

authors： Goldstein CE,Weijer C,Brehaut JC,Campbell M,Fergusson DA,Grimshaw JM,Hemming K,Horn AR,Taljaard M

更新日期：2018-06-25 00:00:00

abstract：BACKGROUND:Spleen qi deficiency (SQD), a syndrome based on traditional Chinese medicine (TCM) theory, is common in patients after radical gastrectomy. SQD manifests with chronic gastrointestinal disorders and systemic symptoms and is challenging to manage. Hou Gu Mi Xi (HGMX) is a dietary TCM formula for SQD. This stud...

journal_title：Trials

authors： Zhou X,Yan DM,Zhu WF,Liu WJ,Nie HY,Xu S,Jiang YP,Zhang KH,Fu Y,Wan YY,Yu XY,Li H,Sun X,Chen XF

更新日期：2019-06-10 00:00:00

abstract：BACKGROUND:Plaque psoriasis is a refractory inflammatory skin disease. The common therapies used to treat plaque psoriasis in traditional Chinese medicine (TCM) and western medicine (WM) have distinct characteristics and advantages. Although a combination of TCM and WM therapies, adjusted to the clinical situation, is ...

journal_title：Trials

authors： Sun X,Zhou X,Wei Y,Yang W,Huang N,Ding Y,Hu R,Guo S,Yang C,Weng H,Zhang Y,Chen X,Ding X,Liu L,Yin Q,Wang R,Li X,Li B

更新日期：2020-03-30 00:00:00

abstract：BACKGROUND:High-protein diets and total diet replacements are becoming increasingly popular for weight regulation; however, further research is needed to elucidate their impact on the physiology of body weight regulation. The aim of this inpatient metabolic balance study is to compare the impact of a high-protein total...

journal_title：Trials

authors： Oliveira CLP,Boulé NG,Sharma AM,Elliott S,Siervo M,Ghosh S,Berg A,Prado CM

更新日期：2019-12-27 00:00:00

abstract：BACKGROUND:There is a high prevalence of pain and post-traumatic symptoms among refugees and feasible interventions to manage these are needed. However, knowledge about the effect of physiotherapy and psychological group interventions among refugees is scarce. Our aim is to determine whether two different interventions...

journal_title：Trials

authors： Hasha W,Fadnes LT,Igland J,Vårdal R,Giusti LM,Strømme EM,Haj-Younes J,Heltne U,Kumar BN,Diaz E

更新日期：2019-12-27 00:00:00

abstract：BACKGROUND:Recent clinical observations have reported the potential benefit of vagus nerve stimulation (VNS) as an adjunctive therapy for pediatric epilepsy. Preliminary evidence suggests that VNS treatment is effective for seizure reduction and mental development in young participants between 3 and 6 years of age who ...

journal_title：Trials

authors： Ji T,Yang Z,Liu Q,Liao J,Yin F,Chen Y,Zou L,Li B,Gao Y,Shu X,Huang S,Gao F,Liang J,Lin SF,Peng J,Song S,Wang J,Che C,Sun W,Tian M,Yang L,Hua Y,Hao Y,Cai L,Li L,Jiang Y

更新日期：2019-01-14 00:00:00

abstract：:International calls for registering all trials involving humans and for sharing the results, and sometimes also the raw data and the trial protocols, have increased in recent years. Such calls have come, for example, from the Organization for Economic Cooperation and Development (OECD), the World Health Organization (...

journal_title：Trials

authors： Gøtzsche PC

更新日期：2011-11-23 00:00:00

abstract：BACKGROUND:Sleep disturbance in older people is an important health issue that is associated with many other health problems. Effective interventions are required to address sleep problems in this group. Acupressure has been suggested as a potential therapeutic technique to improve sleep. The aim of this study is to ev...

journal_title：Trials

authors： Hmwe NTT,Browne G,Mollart L,Allanson V,Chan SW

更新日期：2020-04-25 00:00:00

abstract：BACKGROUND:Neck pain caused by cervical spondylosis (CS) has become one of the most common health problems around the world. Electroacupuncture (EA) has been employed to relieve CS neck pain, but there is limited clinical evidence for its effectiveness. METHODS/DESIGN:This study consists of a randomized controlled tri...

journal_title：Trials

authors： Sun ZR,Yue JH,Zhang QH

更新日期：2013-10-29 00:00:00

abstract：BACKGROUND:Current international guidelines recommend the use of a daily topical exit-site antimicrobial to prevent peritoneal dialysis (PD)-related infections. Although nonantibiotic-based therapies are appealing because they may limit antimicrobial resistance, no controlled trials have been conducted to compare topic...

journal_title：Trials

authors： Nochaiwong S,Ruengorn C,Noppakun K,Panyathong S,Dandecha P,Sood MM,Saenjum C,Awiphan R,Sirilun S,Mongkhon P,Chongruksut W,Thavorn K,Thai Renal Outcomes Research (THOR) Investigators.

更新日期：2019-12-19 00:00:00

abstract：BACKGROUND:Recurrent stroke is a major contributor to stroke-related disability and costs. Improving health-risk behaviours and mental health has the potential to significantly improve recovery, enhance health-related quality of life (HRQoL), independent living, and lower the risk of recurrent stroke. The primary aim w...

journal_title：Trials

authors： Guillaumier A,McCrabb S,Spratt NJ,Pollack M,Baker AL,Magin P,Turner A,Oldmeadow C,Collins C,Callister R,Levi C,Searles A,Deeming S,Wynne O,Denham AMJ,Clancy B,Bonevski B

更新日期：2019-08-09 00:00:00

abstract：BACKGROUND:Acupressure therapy may be potentially beneficial in improving postoperative symptoms like postoperative nausea and vomiting (PONV), pain and sleep disorder and improving postoperative quality of recovery. The primary aim of this study is to investigate the efficacy of acupressure therapy on postoperative pa...

journal_title：Trials

authors： Noll E,Shodhan S,Madariaga MC,Page CR,Santangelo D,Guo X,Al Bizri E,Pryor AD,Romeiser J,Bennett-Guerrero E

更新日期：2017-03-07 00:00:00

abstract：BACKGROUND:Endoscopic ultrasonography (EUS)-guided drainage has become the first-line therapy for late peri-pancreatic fluid collection (PFC). Double pigtail plastic stents (DPPS) and lumen-apposing metal stents (LAMS) are commonly used for PFC drainage. Recently, a multi-institutional consensus on PFC drainage has rec...

journal_title：Trials

authors： Zhu HY,Xie P,Song YX,Li ZS,Jin ZD,Du YQ

更新日期：2018-10-11 00:00:00

abstract：BACKGROUND:Alcohol use disorder (AUD) is a chronic and relapsing condition for which current pharmacological treatments are only modestly effective. The development of efficacious medications for AUD remains a high research priority with recent emphasis on identifying novel molecular targets for AUD treatment and to ef...

journal_title：Trials

authors： Burnette EM,Baskerville WA,Grodin EN,Ray LA

更新日期：2020-09-11 00:00:00