Advances in the management of chronic insomnia.

abstract：OBJECTIVE:To compare the functional results after displaced fractures of the femoral neck treated with internal fixation or hemiarthroplasty. DESIGN:Randomised trial with blinding of assessments of functional results. SETTING:University hospital. PARTICIPANTS:222 patients; 165 (74%) women, mean age 83 years. Inclusi...

journal_title：BMJ (Clinical research ed.)

authors： Frihagen F,Nordsletten L,Madsen JE

更新日期：2007-12-15 00:00:00

abstract：OBJECTIVE:To assess the effects of preventive home visits to elderly people living in the community. DESIGN:Systematic review. SETTING:15 trials retrieved from Medline, Embase, and the Cochrane controlled trial register. MAIN OUTCOME MEASURES:Physical function, psychosocial function, falls, admissions to institution...

journal_title：BMJ (Clinical research ed.)

authors： van Haastregt JC,Diederiks JP,van Rossum E,de Witte LP,Crebolder HF

更新日期：2000-03-18 00:00:00

abstract：OBJECTIVE:To quantify an association between acute kidney injury and use of high potency statins versus low potency statins. DESIGN:Retrospective observational analysis of administrative databases, using nine population based cohort studies and meta-analysis. We performed as treated analyses in each database with a ne...

journal_title：BMJ (Clinical research ed.)

authors： Dormuth CR,Hemmelgarn BR,Paterson JM,James MT,Teare GF,Raymond CB,Lafrance JP,Levy A,Garg AX,Ernst P,Canadian Network for Observational Drug Effect Studies.

更新日期：2013-03-18 00:00:00

abstract：OBJECTIVE:To compare neonatal mortality and morbidity in term infants presenting by the breech and delivered vaginally or by caesarean section. DESIGN:Population based comparison of outcomes. Data derived from the St Mary's maternity information system. SETTING:North West Thames Regional Health Authority, 1988-90. S...

journal_title：BMJ (Clinical research ed.)

authors： Thorpe-Beeston JG,Banfield PJ,Saunders NJ

更新日期：1992-09-26 00:00:00

abstract：OBJECTIVE:To investigate socioeconomic variation among young women in the risk of hospital admission for diseases (including neoplasms) of the female genital system and breast and for the common surgical procedures of dilatation and curettage and hysterectomy. DESIGN:Large nationally representative cohort study with i...

journal_title：BMJ (Clinical research ed.)

authors： Kuh D,Stirling S

更新日期：1995-09-30 00:00:00

abstract：:Hepatorenal syndrome (HRS), the extreme manifestation of renal impairment in patients with cirrhosis, is characterized by reduction in renal blood flow and glomerular filtration rate. Hepatorenal syndrome is diagnosed when kidney function is reduced but evidence of intrinsic kidney disease, such as hematuria, proteinu...

journal_title：BMJ (Clinical research ed.)

authors： Simonetto DA,Gines P,Kamath PS

更新日期：2020-09-14 00:00:00

abstract：OBJECTIVE:To investigate the risk of glioma in adults in relation to mobile phone use. DESIGN:Population based case-control study with collection of personal interview data. SETTING:Five areas of the United Kingdom. PARTICIPANTS:966 people aged 18 to 69 years diagnosed with a glioma from 1 December 2000 to 29 Februa...

journal_title：BMJ (Clinical research ed.)

authors： Hepworth SJ,Schoemaker MJ,Muir KR,Swerdlow AJ,van Tongeren MJ,McKinney PA

更新日期：2006-04-15 00:00:00

abstract：:Objective To determine the attributable risk of community acquired pneumonia on incidence of heart failure throughout the age range of affected patients and severity of the infection.Design Cohort study.Setting Six hospitals and seven emergency departments in Edmonton, Alberta, Canada, 2000-02.Participants 4988 adults...

journal_title：BMJ (Clinical research ed.)

authors： Eurich DT,Marrie TJ,Minhas-Sandhu JK,Majumdar SR

更新日期：2017-02-13 00:00:00

abstract：OBJECTIVES:To examine how insurance companies assess proposals for life assurance from applicants with raised cholesterol concentrations and to determine the excess mortality rating applied. DESIGN:Survey of 49 companies underwriting term life assurance. SETTING:United Kingdom. SUBJECTS:Four fictional men aged 30 se...

journal_title：BMJ (Clinical research ed.)

authors： Neil HA,Mant D

更新日期：1991-04-13 00:00:00

abstract：OBJECTIVES:To compare outcome and costs of general practitioners, senior house officers, and registrars treating patients who attended accident and emergency department with problems assessed at triage as being of primary care type. DESIGN:Prospective intervention study which was later costed. SETTING:Inner city acci...

journal_title：BMJ (Clinical research ed.)

authors： Dale J,Lang H,Roberts JA,Green J,Glucksman E

更新日期：1996-05-25 00:00:00

abstract：:The recent growth in the numbers of published systematic reviews reflects growing recognition of their importance for improving knowledge about the effects of health care. In Britain the NHS R&D Programme has established two centres to prepare systematic reviews of existing information, and the Cochrane Collaboration-...

journal_title：BMJ (Clinical research ed.)

authors： Chalmers I,Haynes B

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVES:To assess the performance of a panel of common single nucleotide polymorphisms (genotypes) associated with type 2 diabetes in distinguishing incident cases of future type 2 diabetes (discrimination), and to examine the effect of adding genetic information to previously validated non-genetic (phenotype based)...

journal_title：BMJ (Clinical research ed.)

authors： Talmud PJ,Hingorani AD,Cooper JA,Marmot MG,Brunner EJ,Kumari M,Kivimäki M,Humphries SE

更新日期：2010-01-14 00:00:00

abstract：OBJECTIVE:To determine the effectiveness of interventions designed to improve outcomes in patients with multimorbidity in primary care and community settings. DESIGN:Systematic review. DATA SOURCES:Medline, Embase, CINAHL, CAB Health, Cochrane central register of controlled trials, the database of abstracts of review...

journal_title：BMJ (Clinical research ed.)

authors： Smith SM,Soubhi H,Fortin M,Hudon C,O'Dowd T

更新日期：2012-09-03 00:00:00

abstract：OBJECTIVE:To compare the prevalence of antibody to and proviral DNA of the retrovirus HTLV-I in relatives of 11 British patients with tropical spastic paraparesis who had migrated from Jamaica before they developed symptoms, and to examine factors possibly related to transmission of HTLV-I. DESIGN:Migrant, family stud...

journal_title：BMJ (Clinical research ed.)

authors： Cruickshank JK,Richardson JH,Morgan OS,Porter J,Klenerman P,Knight J,Newell AL,Rudge P,Dalgleish AG

更新日期：1990-02-03 00:00:00

abstract：:In Oregon, Planned Parenthood and a group of physicians who perform abortions have filed a civil suit against several anti-abortion groups individuals. The suit seeks $200 million in damages and an injunction to bar the defendants from posting information on the Internet that threatens the lives and well-being of the...

journal_title：BMJ (Clinical research ed.)

authors： Charatan F

更新日期：1999-01-23 00:00:00

abstract：:Objective To examine off-label indications for antidepressants in primary care and determine the level of scientific support for off-label prescribing.Design Descriptive study of antidepressant prescriptions written by primary care physicians using an indication based electronic prescribing system.Setting Primary care...

journal_title：BMJ (Clinical research ed.)

authors： Wong J,Motulsky A,Abrahamowicz M,Eguale T,Buckeridge DL,Tamblyn R

更新日期：2017-02-21 00:00:00

abstract：OBJECTIVE:To assess whether a raised serum troponin T concentration would be an independent predictor of death in patients with an acute ischaemic stroke. DESIGN:Observational study. SETTING:Auckland Hospital, Auckland, New Zealand. SUBJECTS:All 181 patients with an acute ischaemic stroke admitted over nine months i...

journal_title：BMJ (Clinical research ed.)

authors： James P,Ellis CJ,Whitlock RM,McNeil AR,Henley J,Anderson NE

更新日期：2000-06-03 00:00:00

abstract：OBJECTIVE:To test whether a drug review and symptom self management and lifestyle advice intervention by community pharmacists could reduce hospital admissions or mortality in heart failure patients. DESIGN:Randomised controlled trial. SETTING:Home based intervention in heart failure patients. PARTICIPANTS:293 patie...

journal_title：BMJ (Clinical research ed.)

authors： Holland R,Brooksby I,Lenaghan E,Ashton K,Hay L,Smith R,Shepstone L,Lipp A,Daly C,Howe A,Hall R,Harvey I

更新日期：2007-05-26 00:00:00

abstract：OBJECTIVE:To quantify the association of indices of central obesity, including waist circumference, hip circumference, thigh circumference, waist-to-hip ratio, waist-to-height ratio, waist-to-thigh ratio, body adiposity index, and A body shape index, with the risk of all cause mortality in the general population, and t...

journal_title：BMJ (Clinical research ed.)

authors： Jayedi A,Soltani S,Zargar MS,Khan TA,Shab-Bidar S

更新日期：2020-09-23 00:00:00

abstract：OBJECTIVE:To study the dynamic function of hypothalamic 5-hydroxytryptamine receptors in patients with postviral fatigue syndrome. DESIGN:Prospective comparison of patients with postviral fatigue syndrome with two control groups. SETTING:Department of neurology, University of Glasgow, Southern General Hospital; depar...

journal_title：BMJ (Clinical research ed.)

authors： Bakheit AM,Behan PO,Dinan TG,Gray CE,O'Keane V

更新日期：1992-04-18 00:00:00

abstract：OBJECTIVES:To investigate the consequences of longstanding obesity on left ventricular mass and structure and to examine the effects of weight loss on these variables. DESIGN:Cross sectional survey and controlled intervention study. SETTING:City of Gothenburg and surrounding areas. Sweden. SUBJECTS:41 obese patients...

journal_title：BMJ (Clinical research ed.)

authors： Karason K,Wallentin I,Larsson B,Sjöström L

更新日期：1997-10-11 00:00:00

abstract：OBJECTIVE:To assess the impact of Stepping Stones, a HIV prevention programme, on incidence of HIV and herpes simplex type 2 (HSV-2) and sexual behaviour. DESIGN:Cluster randomised controlled trial. SETTING:70 villages (clusters) in the Eastern Cape province of South Africa. PARTICIPANTS:1360 men and 1416 women aged...

journal_title：BMJ (Clinical research ed.)

authors： Jewkes R,Nduna M,Levin J,Jama N,Dunkle K,Puren A,Duvvury N

更新日期：2008-08-07 00:00:00

abstract：OBJECTIVE:To compare characteristics of patients and outcomes after elective surgery in independent sector treatment centres (ISTCs) and NHS providers. DESIGN:Follow-up study with outcomes reported by patients three to six months after surgery. SETTING:25 ISTCs and 72 NHS providers in England. Population Consecutive ...

journal_title：BMJ (Clinical research ed.)

authors： Chard J,Kuczawski M,Black N,van der Meulen J,POiS Audit Steering Committee.

更新日期：2011-10-19 00:00:00

abstract：OBJECTIVE:To determine whether cognitive therapy is effective in preventing the worsening of emerging psychotic symptoms experienced by help seeking young people deemed to be at risk for serious conditions such as schizophrenia. DESIGN:Multisite single blind randomised controlled trial. SETTING:Diverse services at fi...

journal_title：BMJ (Clinical research ed.)

authors： Morrison AP,French P,Stewart SL,Birchwood M,Fowler D,Gumley AI,Jones PB,Bentall RP,Lewis SW,Murray GK,Patterson P,Brunet K,Conroy J,Parker S,Reilly T,Byrne R,Davies LM,Dunn G

更新日期：2012-04-05 00:00:00

abstract：:Robots designed for surgery have three main advantages over humans. They have greater three dimensional spatial accuracy, are more reliable, and can achieve much greater precision. Although few surgical robots are yet in clinical trials one or two have advanced to the stage of seeking approval from the UK's Medical De...

journal_title：BMJ (Clinical research ed.)

authors： Buckingham RA,Buckingham RO

更新日期：1995-12-02 00:00:00

abstract：OBJECTIVE:To examine the potential effectiveness and efficiency of different guidelines for statin treatment to reduce deaths from coronary heart disease in the Canadian population. DESIGN:Modelled outcomes of screening and treatment recommendations of six national or international guidelines--from Canada, Australia, ...

journal_title：BMJ (Clinical research ed.)

authors： Manuel DG,Kwong K,Tanuseputro P,Lim J,Mustard CA,Anderson GM,Ardal S,Alter DA,Laupacis A

更新日期：2006-06-17 00:00:00

abstract：OBJECTIVE:To test the hypothesis of an association between neonatal intramuscular vitamin K and childhood leukaemia and other cancers. DESIGN:Population based case-control study with data abstracted from hospital records. SETTING:Scotland. SUBJECTS:Children aged 0-14 years resident in Scotland from 1991-4 and diagno...

journal_title：BMJ (Clinical research ed.)

authors： McKinney PA,Juszczak E,Findlay E,Smith K

更新日期：1998-01-17 00:00:00

abstract：:A committee of French bishops has contradicted the Vatican's condemnation of all methods of contraception by acknowledging that condom use may be necessary in order to prevent the spread of HIV and protect against AIDS. The Social Commission of the French Episcopate made this statement in a book entitled AIDS: Societ...

journal_title：BMJ (Clinical research ed.)

authors： Dorozynski A

更新日期：1996-02-24 00:00:00

abstract：OBJECTIVE:To assess the effect on time to diagnosis of recurrence and on quality of life of transferring primary responsibility for follow up of women with breast cancer in remission from hospital to general practice. DESIGN:Randomised controlled trial with 18 month follow up in which women received routine follow up ...

journal_title：BMJ (Clinical research ed.)

authors： Grunfeld E,Mant D,Yudkin P,Adewuyi-Dalton R,Cole D,Stewart J,Fitzpatrick R,Vessey M

更新日期：1996-09-14 00:00:00

abstract：:Several viral infections have been reported to result in more severe disease in pregnant than non-pregnant women, but the relative risks have not been well characterised. This has now been done for Lassa fever in a prospective study of 68 pregnant and 79 non-pregnant women who were admitted to hospital in Sierra Leone...

journal_title：BMJ (Clinical research ed.)

authors： Price ME,Fisher-Hoch SP,Craven RB,McCormick JB

更新日期：1988-09-03 00:00:00