Advances in the management of chronic insomnia.

abstract：OBJECTIVE:To conduct a systematic review and meta-analysis of cohort studies of body mass index (BMI) and the risk of all cause mortality, and to clarify the shape and the nadir of the dose-response curve, and the influence on the results of confounding from smoking, weight loss associated with disease, and preclinical...

journal_title：BMJ (Clinical research ed.)

authors： Aune D,Sen A,Prasad M,Norat T,Janszky I,Tonstad S,Romundstad P,Vatten LJ

更新日期：2016-05-04 00:00:00

abstract：OBJECTIVE:To describe risk factors for infantile colic. DESIGN:Questionnaire administered by health visitors. SETTING:Sheffield. SUBJECTS:Mothers of 76,747 infants born between 1 August 1975 and 31 May 1988, interviewed when the infant was 1 month old. MAIN OUTCOME MEASURES:Reporting of infantile colic and its dura...

journal_title：BMJ (Clinical research ed.)

authors： Crowcroft NS,Strachan DP

更新日期：1997-05-03 00:00:00

abstract：OBJECTIVE:To determine the association between exposure to radiotherapy for the treatment of prostate cancer and subsequent second malignancies (second primary cancers). DESIGN:Systematic review and meta-analysis of observational studies. DATA SOURCES:Medline and Embase up to 6 April 2015 with no restrictions on year...

journal_title：BMJ (Clinical research ed.)

authors： Wallis CJ,Mahar AL,Choo R,Herschorn S,Kodama RT,Shah PS,Danjoux C,Narod SA,Nam RK

更新日期：2016-03-02 00:00:00

abstract：OBJECTIVE:To compare the efficacy of five probiotic preparations recommended to parents in the treatment of acute diarrhoea in children. Design Randomised controlled clinical trial in collaboration with family paediatricians over 12 months. SETTING:Primary care. PARTICIPANTS:Children aged 3-36 months visiting a famil...

journal_title：BMJ (Clinical research ed.)

authors： Canani RB,Cirillo P,Terrin G,Cesarano L,Spagnuolo MI,De Vincenzo A,Albano F,Passariello A,De Marco G,Manguso F,Guarino A

更新日期：2007-08-18 00:00:00

abstract：OBJECTIVE:To identify and explore parents' concerns when young children become acutely ill. DESIGN:Qualitative study making use of semi-structured one to one and group interviews with parents of preschool children. SETTING:Disadvantaged inner city community. SUBJECTS:95 parents of preschool children. RESULTS:Fever,...

journal_title：BMJ (Clinical research ed.)

authors： Kai J

更新日期：1996-10-19 00:00:00

abstract：OBJECTIVE:To examine association of different measures of serum lipid concentration and obesity with mortality in women. DESIGN:Prospective observational study initiated in 1968-9, follow up examination after 12 years, and follow up study based on death certificates after 20 years. SETTING:Gothenburg, Sweden. SUBJEC...

journal_title：BMJ (Clinical research ed.)

authors： Bengtsson C,Björkelund C,Lapidus L,Lissner L

更新日期：1993-11-27 00:00:00

abstract：OBJECTIVE:To assess the education and workload of preregistration house officers in the four Thames regions. DESIGN:Postal questionnaire. SETTING:Teaching and non-teaching hospitals in the four Thames regions. PARTICIPANTS:1064 Preregistration house officers. RESULTS:Response rate was 70% (740 replies). Nine per ce...

journal_title：BMJ (Clinical research ed.)

authors： Dent TH,Gillard JH,Aarons EJ,Crimlisk HL,Smyth-Pigott PJ

更新日期：1990-03-17 00:00:00

abstract：OBJECTIVES:To determine the prevalence and associations of symptoms of fatigue. DESIGN:Questionnaire survey. SETTING:London general practice. PARTICIPANTS:611 General practice attenders. MAIN OUTCOME MEASURES:Scores on a fatigue questionnaire and reasons given for fatigue. RESULTS:10.2% Of men (17/167) and 10.6% o...

journal_title：BMJ (Clinical research ed.)

authors： David A,Pelosi A,McDonald E,Stephens D,Ledger D,Rathbone R,Mann A

更新日期：1990-11-24 00:00:00

abstract：OBJECTIVE:To assess the incidence and severity of physical and psychosexual symptoms in young women due to ovarian failure caused by total body irradiation for leukaemia and the women's response to hormone treatment. DESIGN:Postal questionnaire and interview. SETTING:Leukaemia unit of oncology hospital. PATIENTS:Con...

journal_title：BMJ (Clinical research ed.)

authors： Cust MP,Whitehead MI,Powles R,Hunter M,Milliken S

更新日期：1989-12-16 00:00:00

abstract：OBJECTIVE:To analyse the cost effectiveness of a national programme to screen blood donors for infection with the human T cell leukaemia/lymphoma virus. DESIGN:Three models for calculating the costs and benefits of screening were developed. The first model analysed the cost of continuously testing all donations; the s...

journal_title：BMJ (Clinical research ed.)

authors： Tynell E,Andersson S,Lithander E,Arneborn M,Blomberg J,Hansson HB,Krook A,Nomberg M,Ramstedt K,Shanwell A,Bjorkman A

更新日期：1998-05-09 00:00:00

abstract：OBJECTIVE:To describe and quantify patterns of injury from antipersonnel mines in terms of distribution of injury, drain on surgical resources, and residual disability. DESIGN:Retrospective analysis. SETTING:Two hospitals for patients injured in war. SUBJECTS:757 patients with injuries from antipersonnel mines. MAI...

journal_title：BMJ (Clinical research ed.)

authors： Coupland RM,Korver A

更新日期：1991-12-14 00:00:00

abstract：OBJECTIVE:To determine whether the use of the UK clinical aptitude test (UKCAT) in the medical schools admissions process reduces the relative disadvantage encountered by certain sociodemographic groups. DESIGN:Prospective cohort study. SETTING:Applicants to 22 UK medical schools in 2009 that were members of the cons...

journal_title：BMJ (Clinical research ed.)

authors： Tiffin PA,Dowell JS,McLachlan JC

更新日期：2012-04-17 00:00:00

abstract：OBJECTIVE:To evaluate risk of late life coronary heart disease associated with being overweight in late middle or old age and to assess whether weight change modifies this risk. DESIGN:Longitudinal study of subjects in the epidemiological follow up study of the national health and nutrition examination survey I. SETT...

journal_title：BMJ (Clinical research ed.)

authors： Harris TB,Launer LJ,Madans J,Feldman JJ

更新日期：1997-06-21 00:00:00

abstract：OBJECTIVE:To compare blood pressure control, satisfaction, and adherence to drug treatment in patients with treated hypertension followed up by their family physicians either every three months or every six months for three years. DESIGN:Randomised equivalence clinical trial. Settings 50 family practices in south east...

journal_title：BMJ (Clinical research ed.)

authors： Birtwhistle RV,Godwin MS,Delva MD,Casson RI,Lam M,MacDonald SE,Seguin R,Rühland L

更新日期：2004-01-24 00:00:00

abstract：:Telephone helplines are an effective way of dealing with health related incidents in which large numbers of people need personal counselling or information for reassurance or case finding. Helplines often have to be set up at short notice, which is labour intensive and makes recruitment of appropriate staff difficult....

journal_title：BMJ (Clinical research ed.)

authors： Stark C,Christie P,Marr AC

更新日期：1994-07-02 00:00:00

abstract：OBJECTIVE:This study updates work published in 1998, which found that of 47 rating instruments appearing on websites offering health information, 14 described how they were developed, five provided instructions for use, and none reported the interobserver reliability and construct validity of the measurements. DESIGN:...

journal_title：BMJ (Clinical research ed.)

authors： Gagliardi A,Jadad AR

更新日期：2002-03-09 00:00:00

abstract：OBJECTIVE:To estimate the risk of acute hepatotoxicity associated with nimesulide compared with other non-steroidal anti-inflammatory drugs. DESIGN:Retrospective cohort and nested case-control study. SETTING:Umbria region, Italy. PARTICIPANTS:400 000 current, recent, and past users (almost 2 million prescriptions) o...

journal_title：BMJ (Clinical research ed.)

authors： Traversa G,Bianchi C,Da Cas R,Abraha I,Menniti-Ippolito F,Venegoni M

更新日期：2003-07-05 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of a monovalent rotavirus vaccine against severe rotavirus disease and to assess its impact on diarrhoea in children aged less than 2 years after national introduction in El Salvador, a low-middle income country in Central America. DESIGN:Matched case-control study. SETTING:Sev...

journal_title：BMJ (Clinical research ed.)

authors： de Palma O,Cruz L,Ramos H,de Baires A,Villatoro N,Pastor D,de Oliveira LH,Kerin T,Bowen M,Gentsch J,Esposito DH,Parashar U,Tate J,Patel M

更新日期：2010-06-15 00:00:00

abstract：:In just 3 months in 1991, WHO increased its estimate of the number of people infected with HIV in all of Asia 2 fold (500,000-1 million). By 2000, WHO estimated that there will be 250,000 new cases each year in India and Thailand alone where HIV infection has spread most rapidly. A professor from the All India Insti...

journal_title：BMJ (Clinical research ed.)

authors： Tanne JH

更新日期：1991-06-29 00:00:00

abstract：OBJECTIVES:To assess incidence of and mortality from cancer in hypertensive patients taking atenolol, comparing the findings with two control populations and with hypertensive patients taking other drugs. DESIGN:Retrospective analysis of patients first seen in the Glasgow Blood Pressure Clinic between 1972 and 1990. P...

journal_title：BMJ (Clinical research ed.)

authors： Hole DJ,Hawthorne VM,Isles CG,McGhee SM,Robertson JW,Gillis CR,Wapshaw JA,Lever AF

更新日期：1993-03-06 00:00:00

abstract：OBJECTIVE:To describe the association between epithelial cell IgM, which has previously been associated with an increased incidence of loss of renal graft in children, with a novel cutaneous eruption and unexplained native renal disease. DESIGN:Observational study on children with epithelial cell antibody presenting w...

journal_title：BMJ (Clinical research ed.)

authors： Deal JE,Groves RW,Harmer AW,Welsh KI,MacDonald DM,Rigden SP

更新日期：1991-07-20 00:00:00

abstract：OBJECTIVES:To investigate the circumstances since the 1950s in which people who were attracted to members of the same sex received treatments to change their sexual orientation, the referral pathway and the process of therapy, and its aftermath. DESIGN:A nationwide study based on qualitative interviews. PARTICIPANTS:...

journal_title：BMJ (Clinical research ed.)

authors： Smith G,Bartlett A,King M

更新日期：2004-02-21 00:00:00

abstract：:Several forces have resulted in the creation in Tayside of the first formally integrated unit of undergraduate and postgraduate education in general practice in the United Kingdom. Forces that helped this integration included the desire for change, national developments in education, financial support through funds se...

journal_title：BMJ (Clinical research ed.)

authors： Bain J,Scott R,Snadden D

更新日期：1995-06-17 00:00:00

abstract：OBJECTIVE:To investigate the relation between total fat intake and body weight in adults and children. DESIGN:Systematic review and meta-analysis of randomised controlled trials and cohort studies. DATA SOURCES:Medline, Embase, CINAHL, and the Cochrane Central Register of Controlled Trials to June 2010. INCLUSION CR...

journal_title：BMJ (Clinical research ed.)

authors： Hooper L,Abdelhamid A,Moore HJ,Douthwaite W,Skeaff CM,Summerbell CD

更新日期：2012-12-06 00:00:00

abstract：OBJECTIVES:To estimate the prevalence and incidence of divorce among US physicians compared with other healthcare professionals, lawyers, and non-healthcare professionals, and to analyze factors associated with divorce among physicians. DESIGN:Retrospective analysis of nationally representative surveys conducted by th...

journal_title：BMJ (Clinical research ed.)

authors： Ly DP,Seabury SA,Jena AB

更新日期：2015-02-18 00:00:00

abstract：OBJECTIVES:To investigate whether routinely collected data from hospital episode statistics could be used to identify the gynaecologist Rodney Ledward, who was suspended in 1966 and was the subject of the Ritchie inquiry into quality and practice within the NHS. DESIGN:A mixed scanning approach was used to identify se...

journal_title：BMJ (Clinical research ed.)

authors： Harley M,Mohammed MA,Hussain S,Yates J,Almasri A

更新日期：2005-04-23 00:00:00

abstract：AIM:To compare perinatal morbidity and mortality for babies delivered in water with rates for babies delivered conventionally (not in water). DESIGN:Surveillance study (of all consultant paediatricians) and postal survey (of all NHS maternity units). SETTING:British Isles (surveillance study); England and Wales (post...

journal_title：BMJ (Clinical research ed.)

authors： Gilbert RE,Tookey PA

更新日期：1999-08-21 00:00:00

abstract：OBJECTIVE:To assess the risk of bias associated with missing outcome data in systematic reviews. DESIGN:Imputation study. SETTING:Systematic reviews. POPULATION:100 systematic reviews that included a group level meta-analysis with a statistically significant effect on a patient important dichotomous efficacy outcome...

journal_title：BMJ (Clinical research ed.)

authors： Kahale LA,Khamis AM,Diab B,Chang Y,Lopes LC,Agarwal A,Li L,Mustafa RA,Koujanian S,Waziry R,Busse JW,Dakik A,Schünemann HJ,Hooft L,Scholten RJ,Guyatt GH,Akl EA

更新日期：2020-08-26 00:00:00

abstract：:According to a London physician, women with epilepsy taking antiepileptic drugs can take combined oral contraceptives (OCs). It is usual to recommend a combined OC preparation containing at least 50 mcg of estrogen (Ovran) from patients taking enzyme-inducing antiepileptic drugs; this can be increased to 60 mcg by ta...

journal_title：BMJ (Clinical research ed.)

authors： O'Brien MD,Gilmour-White S

更新日期：1993-08-21 00:00:00

abstract：OBJECTIVE:To evaluate the effects of a multifaceted empowerment strategy on the actual use of single embryo transfer after in vitro fertilisation. DESIGN:Randomised controlled trial. SETTING:Five in vitro fertilisation clinics in the Netherlands. PARTICIPANTS:308 couples (women aged <40) on the waiting list for a fi...

journal_title：BMJ (Clinical research ed.)

authors： van Peperstraten A,Nelen W,Grol R,Zielhuis G,Adang E,Stalmeier P,Hermens R,Kremer J

更新日期：2010-09-30 00:00:00