Possible upregulation of hypothalamic 5-hydroxytryptamine receptors in patients with postviral fatigue syndrome.

abstract：:This paper examines the impact of marital status on maternal mortality in the period before and the period after German reunification in the area covered by the former East Germany. Maternal mortality ratio prior to the reunification was stable and declined after reunification. This can be attributed to the adoption ...

journal_title：BMJ (Clinical research ed.)

authors： Razum O,Jahn A,Snow R

更新日期：1999-10-23 00:00:00

abstract：OBJECTIVES:To describe the menstrual experience of women referred for menstrual problems, in particular menorrhagia (excessive menstrual loss), and to assess associations with reasons for referral given by their general practitioners, the women's understanding of the reasons for their attendance at the hospital clinics...

journal_title：BMJ (Clinical research ed.)

authors： Warner P,Critchley HO,Lumsden MA,Campbell-Brown M,Douglas A,Murray G

更新日期：2001-07-07 00:00:00

abstract：OBJECTIVE:To synthesise the views of patients and carers in decision making regarding treatment for chronic kidney disease, and to determine which factors influence those decisions. DESIGN:Systematic review of qualitative studies of decision making and choice for dialysis, transplantation, or palliative care, and them...

journal_title：BMJ (Clinical research ed.)

authors： Morton RL,Tong A,Howard K,Snelling P,Webster AC

更新日期：2010-01-19 00:00:00

abstract：OBJECTIVE:To examine the effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared with general practitioners. DESIGN:Multicentre randomised controlled trial. SETTING:Nine memory clinics and 159 general practitioners in the Netherlands. PARTICIPANTS:175 patients with a ne...

journal_title：BMJ (Clinical research ed.)

authors： Meeuwsen EJ,Melis RJ,Van Der Aa GC,Golüke-Willemse GA,De Leest BJ,Van Raak FH,Schölzel-Dorenbos CJ,Verheijen DC,Verhey FR,Visser MC,Wolfs CA,Adang EM,Olde Rikkert MG

更新日期：2012-05-15 00:00:00

abstract：:Seventy five consecutive users of the Leeds disabled living foundation were surveyed. Two thirds of these users were at least moderately severely disabled. Forty eight of the 65 people (74%) who completed the questionnaire were recommended aids, and 33 had received some at the end of the survey. Only 10 of 28 people h...

journal_title：BMJ (Clinical research ed.)

authors： Chamberlain MA,Gallop J

更新日期：1988-12-10 00:00:00

abstract：OBJECTIVES:To assess the experiences of obstetricians in England and Wales of serum screening for Down's syndrome. DESIGN:Postal questionnaire survey. SUBJECTS:Questionnaires were sent to all practising obstetricians in England and Wales with nonacademic appointments who had not participated in an earlier (randomly s...

journal_title：BMJ (Clinical research ed.)

authors： Green JM

更新日期：1994-09-24 00:00:00

abstract：OBJECTIVE:To compare the functional results after displaced fractures of the femoral neck treated with internal fixation or hemiarthroplasty. DESIGN:Randomised trial with blinding of assessments of functional results. SETTING:University hospital. PARTICIPANTS:222 patients; 165 (74%) women, mean age 83 years. Inclusi...

journal_title：BMJ (Clinical research ed.)

authors： Frihagen F,Nordsletten L,Madsen JE

更新日期：2007-12-15 00:00:00

abstract：OBJECTIVE:To determine whether peer review medical audit in a primary care setting changes clinical behaviour in relation to the management of hypertension. DESIGN:Review of medical records in general practices to identify hypertensive patients followed up by assessment of the pre-educational and post-educational mana...

journal_title：BMJ (Clinical research ed.)

authors： Mashru M,Lant A

更新日期：1997-03-29 00:00:00

abstract：OBJECTIVES: To determine whether late mortality after sepsis is driven predominantly by pre-existing comorbid disease or is the result of sepsis itself. DEIGN: Observational cohort study. SETTING: US Health and Retirement Study. PARTICIPANTS: 960 patients aged ≥65 (1998-2010) with fee-for-service Medicare coverage w...

journal_title：BMJ (Clinical research ed.)

authors： Prescott HC,Osterholzer JJ,Langa KM,Angus DC,Iwashyna TJ

更新日期：2016-05-17 00:00:00

abstract：OBJECTIVES:To determine the accuracy and acceptability to patients of non-endoscopic screening for Barrett's oesophagus, using an ingestible oesophageal sampling device (Cytosponge) coupled with immunocytochemisty for trefoil factor 3. DESIGN:Prospective cohort study. SETTING:12 UK general practices, with gastroscopi...

journal_title：BMJ (Clinical research ed.)

authors： Kadri SR,Lao-Sirieix P,O'Donovan M,Debiram I,Das M,Blazeby JM,Emery J,Boussioutas A,Morris H,Walter FM,Pharoah P,Hardwick RH,Fitzgerald RC

更新日期：2010-09-10 00:00:00

abstract：OBJECTIVES:To determine whether an aid to the diagnosis of pigmented skin lesions reduces the ratio of benign lesions to melanomas excised in general practice. DESIGN:Controlled trial randomised by practice. SETTING:General practices in Perth, Western Australia. PARTICIPANTS:468 general practitioners in 223 practice...

journal_title：BMJ (Clinical research ed.)

authors： English DR,Burton RC,del Mar CB,Donovan RJ,Ireland PD,Emery G

更新日期：2003-08-16 00:00:00

abstract：OBJECTIVE:To assess the risk of adverse perinatal events of vaccination of pregnant women with an MF59 adjuvanted vaccine. DESIGN:Cross sectional multicentre study. SETTING:49 public hospitals in major cities in Argentina, from September 2010 to May 2011. PARTICIPANTS:30,448 mothers (7293 vaccinated) and their 30,76...

journal_title：BMJ (Clinical research ed.)

authors： Rubinstein F,Micone P,Bonotti A,Wainer V,Schwarcz A,Augustovski F,Pichon Riviere A,Karolinski A,EVA Study Research Group Estudio Embarazo y Vacuna Antigripal.

更新日期：2013-02-04 00:00:00

abstract：OBJECTIVES:To assess the long term clinical and cost effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) intervention compared with usual care in people with newly diagnosed type 2 diabetes. DESIGN:We undertook a cost-utility analysis that used data from a 12 month, mu...

journal_title：BMJ (Clinical research ed.)

authors： Gillett M,Dallosso HM,Dixon S,Brennan A,Carey ME,Campbell MJ,Heller S,Khunti K,Skinner TC,Davies MJ

更新日期：2010-08-20 00:00:00

abstract：OBJECTIVES:To measure the potential for cadaver organ retrieval in New South Wales and to determine the reasons for potential donors failing to become actual donors. DESIGN:Prospective audit of all patients dying in five hospitals in New South Wales between 1 December 1989 and 30 November 1990; quality assurance of th...

journal_title：BMJ (Clinical research ed.)

authors： Hibberd AD,Pearson IY,McCosker CJ,Chapman JR,Macdonald GJ,Thompson JF,O'Connell DL,Mohacsi PJ,McLoughlin MP,Spratt PM

更新日期：1992-05-23 00:00:00

abstract：:The relations among parental reports of respiratory symptoms, bronchospasm measured after exercise, and the presence of visible fungal mould in the home was assessed in a population sample of 7 year old children (n = 873). Wheeze in the past year was the symptom most closely associated with reported dampness and parti...

journal_title：BMJ (Clinical research ed.)

authors： Strachan DP

更新日期：1988-11-12 00:00:00

abstract：OBJECTIVES:To assess heat related mortalities in relation to climate within Europe. DESIGN:Observational population study. SETTING:North Finland, south Finland, Baden-Württemberg, Netherlands, London, north Italy, and Athens. SUBJECTS:People aged 65-74. MAIN OUTCOME MEASURES:Mortalities at temperatures above, below...

journal_title：BMJ (Clinical research ed.)

authors： Keatinge WR,Donaldson GC,Cordioli E,Martinelli M,Kunst AE,Mackenbach JP,Nayha S,Vuori I

更新日期：2000-09-16 00:00:00

abstract：OBJECTIVES:To relate cancer since entry into the Framingham Heart Study with the risk of incident Alzheimer's disease and to estimate the risk of incident cancer among participants with and without Alzheimer's disease. DESIGN:Community based prospective cohort study; nested age and sex matched case-control study. SET...

journal_title：BMJ (Clinical research ed.)

authors： Driver JA,Beiser A,Au R,Kreger BE,Splansky GL,Kurth T,Kiel DP,Lu KP,Seshadri S,Wolf PA

更新日期：2012-03-12 00:00:00

abstract：OBJECTIVE:To investigate estimation of calorie (energy) content of meals from fast food restaurants in adults, adolescents, and school age children. DESIGN:Cross sectional study of repeated visits to fast food restaurant chains. SETTING:89 fast food restaurants in four cities in New England, United States: McDonald's...

journal_title：BMJ (Clinical research ed.)

authors： Block JP,Condon SK,Kleinman K,Mullen J,Linakis S,Rifas-Shiman S,Gillman MW

更新日期：2013-05-23 00:00:00

abstract：OBJECTIVE:To quantify and compare the contribution of 306 diseases and injuries to the changes in health adjusted life expectancy at birth (HALE0) between 1990 and 2013. DESIGN:Retrospective demographic analysis based on aggregated data and using life table technique, Sullivan method, and decomposition method for diff...

journal_title：BMJ (Clinical research ed.)

authors： Chen H,Chen G,Zheng X,Guo Y

更新日期：2019-03-27 00:00:00

abstract：OBJECTIVES:To explore the assumptions underlying consumers' responses to questions of resource priorities in the NHS. DESIGN:Qualitative analysis of semi-structured interviews with a heterogeneous sample of 16 patients drawn from a general practice. RESULTS:Interviewees were not persuaded that they had a legitimate r...

journal_title：BMJ (Clinical research ed.)

authors： Dicker A,Armstrong D

更新日期：1995-10-28 00:00:00

abstract：OBJECTIVE:To assess the effect on time to diagnosis of recurrence and on quality of life of transferring primary responsibility for follow up of women with breast cancer in remission from hospital to general practice. DESIGN:Randomised controlled trial with 18 month follow up in which women received routine follow up ...

journal_title：BMJ (Clinical research ed.)

authors： Grunfeld E,Mant D,Yudkin P,Adewuyi-Dalton R,Cole D,Stewart J,Fitzpatrick R,Vessey M

更新日期：1996-09-14 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of two peritendinous autologous blood injections in addition to a standardised eccentric calf strengthening programme in improving pain and function in patients with mid-portion Achilles tendinopathy. DESIGN:Single centre, participant and single assessor blinded, parallel group, r...

journal_title：BMJ (Clinical research ed.)

authors： Bell KJ,Fulcher ML,Rowlands DS,Kerse N

更新日期：2013-04-18 00:00:00

abstract：OBJECTIVE:To investigate any long term effects of traumatic birth and obstetric procedures in relation to suicide by violent means in offspring as adults. DESIGN:Prospective case-control study. SETTING:Stockholm, Sweden. SUBJECTS:242 adults who committed suicide by violent means from 1978 to 1995, and who were born ...

journal_title：BMJ (Clinical research ed.)

authors： Jacobson B,Bygdeman M

更新日期：1998-11-14 00:00:00

abstract：OBJECTIVES:To assess the associations between both uric acid levels and hyperuricaemia, with ischaemic heart disease and blood pressure, and to explore the potentially confounding role of body mass index. DESIGN:Mendelian randomisation analysis, using variation at specific genes (SLC2A9 (rs7442295) as an instrument fo...

journal_title：BMJ (Clinical research ed.)

authors： Palmer TM,Nordestgaard BG,Benn M,Tybjærg-Hansen A,Davey Smith G,Lawlor DA,Timpson NJ

更新日期：2013-07-18 00:00:00

abstract：OBJECTIVE:To assess the risk of bias associated with missing outcome data in systematic reviews. DESIGN:Imputation study. SETTING:Systematic reviews. POPULATION:100 systematic reviews that included a group level meta-analysis with a statistically significant effect on a patient important dichotomous efficacy outcome...

journal_title：BMJ (Clinical research ed.)

authors： Kahale LA,Khamis AM,Diab B,Chang Y,Lopes LC,Agarwal A,Li L,Mustafa RA,Koujanian S,Waziry R,Busse JW,Dakik A,Schünemann HJ,Hooft L,Scholten RJ,Guyatt GH,Akl EA

更新日期：2020-08-26 00:00:00

abstract：OBJECTIVES:To identify risk factors predisposing to the development of flucloxacillin associated jaundice. DESIGN:Case-control study. Medical records of cases and controls were reviewed and information recorded on standard data collection forms. SETTING:Alfred Hospital recruiting subjects from Melbourne, Sydney, and ...

journal_title：BMJ (Clinical research ed.)

authors： Fairley CK,McNeil JJ,Desmond P,Smallwood R,Young H,Forbes A,Purcell P,Boyd I

更新日期：1993-01-23 00:00:00

abstract：OBJECTIVES:To determine the impact on teenage pregnancy of interventions that address the social disadvantage associated with early parenthood and to assess the appropriateness of such interventions for young people in the United Kingdom. DESIGN:Systematic review, including a statistical meta-analysis of controlled tr...

journal_title：BMJ (Clinical research ed.)

authors： Harden A,Brunton G,Fletcher A,Oakley A

更新日期：2009-11-12 00:00:00

abstract：:For the past 18 years there has been a proliferation of European committees, boards, associations, colleges, and working groups set up to promote the harmonisation of specialist training in Europe. It has been taken as read that this objective is desirable. The fact that these bodies have achieved remarkably little is...

journal_title：BMJ (Clinical research ed.)

authors： Brearley S

更新日期：1995-07-29 00:00:00

abstract：OBJECTIVE:To estimate the usefulness of serum concentrations of the complex of trypsin 2 and alpha 1 antitrypsin in diagnosing and assessing the severity of acute pancreatitis in comparison with serum C reactive protein, amylase, and trypsinogen 2 concentrations (reference markers). DESIGN:Markers were measured in con...

journal_title：BMJ (Clinical research ed.)

authors： Hedström J,Sainio V,Kemppainen E,Haapiainen R,Kivilaakso E,Schröder T,Leinonen J,Stenman UH

更新日期：1996-08-10 00:00:00

abstract：OBJECTIVE:To assess strategies for advice on analgesia and steam inhalation for respiratory tract infections. DESIGN:Open pragmatic parallel group factorial randomised controlled trial. SETTING:Primary care in United Kingdom. PARTICIPANTS:Patients aged ≥ 3 with acute respiratory tract infections. INTERVENTION:889 p...

journal_title：BMJ (Clinical research ed.)

authors： Little P,Moore M,Kelly J,Williamson I,Leydon G,McDermott L,Mullee M,Stuart B,PIPS Investigators.

更新日期：2013-10-25 00:00:00