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Raised mammographic density: causative mechanisms and biological consequences.

Abstract：

:High mammographic density is the most important risk factor for breast cancer, after ageing. However, the composition, architecture, and mechanical properties of high X-ray density soft tissues, and the causative mechanisms resulting in different mammographic densities, are not well described. Moreover, it is not known how high breast density leads to increased susceptibility for cancer, or the extent to which it causes the genomic changes that characterise the disease. An understanding of these principals may lead to new diagnostic tools and therapeutic interventions.

journal_name

Breast Cancer Res

journal_title

Breast cancer research : BCR

authors

Sherratt MJ,McConnell JC,Streuli CH

doi

10.1186/s13058-016-0701-9

subject

Has Abstract

pub_date

2016-05-03 00:00:00

pages

45

issue

1

eissn

1465-5411

issn

1465-542X

pii

10.1186/s13058-016-0701-9

journal_volume

18

pub_type

杂志文章,评审

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