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Breast cancer in association with thyroid disorders.

Abstract：

BACKGROUND:The relationship between breast cancer and thyroid diseases is controversial. Discrepant results have been reported in the literature. The incidences of autoimmune and nonautoimmune thyroid diseases were investigated in patients with breast cancer and age-matched control individuals without breast or thyroid disease. METHODS:Clinical and ultrasound evaluation of thyroid gland, determination of serum thyroid hormone and antibody levels, and fine-needle aspiration of thyroid gland were performed in 150 breast cancer patients and 100 control individuals. RESULTS:The mean values for anti-thyroid peroxidase antibodies were significantly higher in breast cancer patients than in control individuals (P = 0.030). The incidences of autoimmune and nonautoimmune thyroid diseases were higher in breast cancer patients than in control individuals (38% versus 17%, P = 0.001; 26% versus 9%, P = 0.001, respectively). CONCLUSION:Our results indicate an increased prevalence of autoimmune and nonautoimmune thyroid diseases in breast cancer patients.

journal_name

Breast Cancer Res

journal_title

Breast cancer research : BCR

authors

Turken O,NarIn Y,DemIrbas S,Onde ME,Sayan O,KandemIr EG,YaylacI M,Ozturk A

doi

10.1186/bcr609

keywords:

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

R110-3

issue

5

eissn

1465-5411

issn

1465-542X

journal_volume

5

pub_type

杂志文章

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