Gender-specific associations of serum sex hormone-binding globulin with features of metabolic syndrome in children.

abstract：BACKGROUND:Evidences support the benefits of moderate- to high-intensity statins for patients with acute myocardial infarction (AMI) except for those with type 2 diabetes mellitus (T2DM) on dialysis after AMI. This study was aimed to investigate the safety and efficacy of secondary prevention of cardiovascular diseases...

journal_title：Diabetology & metabolic syndrome

authors： Li YR,Tsai SS,Lin YS,Chung CM,Chen ST,Sun JH,Liou MJ,Chen TH

更新日期：2017-09-19 00:00:00

abstract：BACKGROUND:Type 1 diabetes mellitus in pregnant women is associated with an increased risk of congenital malformations, obstetric complications, neonatal morbidity, and mortality. Our aim was to evaluate which factors from the first trimester of pregnancy have a significant impact on the pregnancy outcomes of women wit...

journal_title：Diabetology & metabolic syndrome

authors： Timar B,Timar R,Albai A,Stoian D,Nitu R,Craina M

更新日期：2014-11-22 00:00:00

abstract：BACKGROUND:Non-alcoholic steatohepatitis (NASH) is highly associated with metabolic syndrome, a major cause of morbidity in the globalized society. The renin-angiotensin system (RAS) influences hepatic fatty acid metabolism, inflammation and fibrosis. Thus, in the present study, we aimed to evaluate the effect of alisk...

journal_title：Diabetology & metabolic syndrome

authors： Ramalho FN,Sanches SC,Foss MC,Augusto MJ,Silva DM,Oliveira AM,Ramalho LN

更新日期：2017-10-13 00:00:00

abstract：BACKGROUND:Using patient data from the GetGoal-Duo1, -L, and L-Asia trials, the objectives of this study were to evaluate and compare the impact of lixisenatide once-daily add-on treatment to basal insulin therapy ±oral antidiabetic drugs (OADs) among type 2 diabetes (T2DM) patients subdivided into groups, based on the...

journal_title：Diabetology & metabolic syndrome

authors： Eto K,Naito Y,Seino Y

更新日期：2015-11-21 00:00:00

abstract：Background:Adipokines are involved in the pathogenesis of metabolic disorders including obesity and type 2 diabetes mellitus (T2DM). This study investigates the levels of leptin, resistin, visfatin, secreted frizzled-related protein 5 (SFRP5), monocyte chemoattractant protein-1 (MCP-1) and retinol-binding protein 4 (RB...

journal_title：Diabetology & metabolic syndrome

authors： Toan NL,Van Hoan N,Cuong DV,Dung NV,Dung PT,Hang NT,Dieu DTH,Chung DT,Son HA,Phong PX,Lenon GB,Van De D,Van Tong H

更新日期：2018-05-15 00:00:00

abstract：Background:Population attributable fractions (PAFs) are frequently used to quantify the proportion of Type 2 diabetes cases due to single risk factors, an approach which may result in an overestimation of their individual contributions. This study aimed to examine Type 2 diabetes incidence associated with multiple risk...

journal_title：Diabetology & metabolic syndrome

authors： Naicker K,Manuel D,Øverland S,Skogen JC,Johnson JA,Sivertsen B,Colman I

更新日期：2018-11-22 00:00:00

abstract：Background:Metabolic syndrome is characterized by macrophage infiltration and inflammatory responses-metaflammation in adipose tissue. IL-6 and IL-1β could mediate the inflammatory responses in macrophage stimulated-preadipocytes by modulating MAPK and NF-κB pathways. To test this hypothesis we used antibodies to block...

journal_title：Diabetology & metabolic syndrome

authors： Zhu J,Bing C,Wilding JPH

更新日期：2019-01-25 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme (ACE) inhibitors are widely prescribed for patients with diabetes as a nephroprotector drug or to treat hypertension. Generally they are safe for clinical practice, but the relationship between these drugs and angioedema is known. The exact mechanism for ACE inhibitors-induced a...

journal_title：Diabetology & metabolic syndrome

authors： Alencar RC,Cobas RA,Gomes MB

更新日期：2010-01-20 00:00:00

abstract：UNLABELLED: BACKGROUND:Achieving good glycemic control is of paramount importance in the reduction of diabetes mellitus (DM) associated morbidity and mortality. Insulin plays a key role in the management of DM but unfortunately whilst some healthcare providers present insulin as a treatment of last resort , patients o...

journal_title：Diabetology & metabolic syndrome

authors： Ogbera AO,Kuku SF

更新日期：2012-12-02 00:00:00

abstract：BACKGROUND:Many patients with chronic heart failure (CHF) are believed to have unrecognized diabetes, which is associated with a worse prognosis. This study aimed to describe glucose tolerance in a general stable CHF population and to identify determinants of glucose tolerance focusing on body composition and skeletal ...

journal_title：Diabetology & metabolic syndrome

authors： Stevens AL,Hansen D,Vandoren V,Westerlaken R,Creemers A,Eijnde BO,Dendale P

更新日期：2014-03-27 00:00:00

abstract：Background:Genome-wide association studies have shown that risk alleles on chromosome 9p21.3 locus, are associated with increasing the risk of cardiovascular diseases (CVDs). Several epidemiological studies have found that metabolic syndrome (MetS) is associated with CVDs. Dietary antioxidants also have shown to have p...

journal_title：Diabetology & metabolic syndrome

authors： Mirzababaei A,Mollahosseini M,Rahimi MH,Yekaninejad MS,Maghbooli Z,Sobhani R,Mirzaei K

更新日期：2018-10-18 00:00:00

abstract：BACKGROUND:Visceral adiposity contributes to cardiometabolic risk, and visceral adiposity index (VAI) had significant correlation with visceral adiposity. We aimed to explore whether VAI was associated with cardiac structure and function and assess the impact of the cut-off points of VAI defining visceral adipose dysfu...

journal_title：Diabetology & metabolic syndrome

authors： Han L,Fu KL,Zhao J,Wang ZH,Tang MX,Wang J,Wang H,Zhang Y,Zhang W,Zhong M

更新日期：2014-12-22 00:00:00

abstract：BACKGROUND:Hypertriglyceridemia (HTG) is considered an independent risk factor for major adverse cardiovascular events (MACE). METHODS:This study analyzed the effects of various agents on MACE risk reduction in HTG (serum triglyceride ≥ 150 mg/dl) populations by performing a network meta-analysis. We performed a frequ...

journal_title：Diabetology & metabolic syndrome

authors： Qi YY,Yan L,Wang ZM,Wang X,Meng H,Li WB,Chen DC,Li M,Liu J,An ST

更新日期：2021-01-29 00:00:00

abstract：BACKGROUND:Dipeptidyl peptidase-4 (DDP4) is an enzyme responsible for glucagon-like peptide-1 inactivation and plays an important role in glucose metabolism. OBJECTIVE:The aim of this study was to evaluate DPP4 levels in patients with familial partial lipodystrophy type 2 (FPLD2) and correlate it with body fat distrib...

journal_title：Diabetology & metabolic syndrome

authors： Valerio CM,de Almeida JS,Moreira RO,Aguiar LBS,Siciliano PO,Carvalho DP,Godoy-Matos AF

更新日期：2017-04-24 00:00:00

abstract：Background:Obesity is associated with several comorbidities, such as cardiovascular disease and type 2 diabetes mellitus, and may have its origin in early life stages, such as in the lactation period, through metabolic programming. Physical activity aids in decreasing the chances of developing cardiovascular and metabo...

journal_title：Diabetology & metabolic syndrome

authors： de Lade CG,Andreazzi AE,Bolotari M,Costa VMG,Peters VM,Guerra MO

更新日期：2018-09-26 00:00:00

abstract：: In recent decades, Diabetes Mellitus has become a severe and growing global public healthcare problem due to the increase of its prevalence, morbidity and mortality. Post-transplant diabetes mellitus (PTDM) is a complication which takes place after a solid organ transplant, and its incidence is widely variable, rangi...

journal_title：Diabetology & metabolic syndrome

authors： Gomes MB,Cobas RA

更新日期：2009-10-05 00:00:00

abstract：BACKGROUND:Long non-coding RNA cyclin-dependent kinase inhibitor 2B antisense RNA 1 (CDKN2B-AS1) has been reported to be related to diabetic nephropathy (DN) progression. However, the regulatory mechanisms of CDKN2B-AS1 in DN are unclear. METHODS:High glucose (HG) was used to induce human mesangial cells (HMCs) for es...

journal_title：Diabetology & metabolic syndrome

authors： Chang J,Yu Y,Fang Z,He H,Wang D,Teng J,Yang L

更新日期：2020-12-09 00:00:00

abstract：BACKGROUND:This study aimed to determine self-monitoring practices, awareness to dietary modifications and barriers to medication adherence among physically disabled type 2 diabetes mellitus patients. METHODS:Interview sessions were conducted at diabetes clinic-Penang general hospital. The invited participants represe...

journal_title：Diabetology & metabolic syndrome

authors： Gillani SW,Sulaiman SAS,Abdul MIM,Saad SY

更新日期：2017-07-24 00:00:00

abstract：BACKGROUND:Helicobacter pylori (H. pylori) infection is reported to be associated with various extragastrointestinal conditions such as insulin resistance, diabetes mellitus and metabolic syndrome. H. pylori infection and type 2 diabetes mellitus (T2DM) are associated with oxidative stress, this cross-relation between ...

journal_title：Diabetology & metabolic syndrome

authors： Nasif WA,Mukhtar MH,Nour Eldein MM,Ashgar SS

更新日期：2016-05-03 00:00:00

abstract：Background:New technologies are changing diabetes treatment and contributing better outcomes in developed countries. To our knowledge, no previous studies have investigated the comparative effect of sensor-based monitoring on glycemic markers in developing countries like Brazil. The present study aims to evaluate the u...

journal_title：Diabetology & metabolic syndrome

authors： Calliari LEP,Krakauer M,Vianna AGD,Ram Y,Barbieri DE,Xu Y,Dunn TC

更新日期：2020-01-07 00:00:00

abstract：BACKGROUND:Reduced insulin sensitivity not only contributes to the pathogenesis of type 2 diabetes but is also linked to multiple metabolic risk factors and cardiovascular diseases (CVD). A prolonged heart rate-corrected QT interval (QTc interval) is related to ventricular arrhythmias and CVD mortality and exhibits a h...

journal_title：Diabetology & metabolic syndrome

authors： Yang XH,Su JB,Zhang XL,Zhao LH,Xu F,Wang XQ,Cheng XB

更新日期：2017-09-11 00:00:00

abstract：BACKGROUND:The single-center, open-label, four-arm, exploratory study investigates the relation of different anti-diabetics to serum levels of active TGF-β, a known pro-fibrotic stimulus, before and after a defined test meal. FINDINGS:We investigated sera of patients with type 2 diabetes mellitus (T2DM) treated with m...

journal_title：Diabetology & metabolic syndrome

authors： Pscherer S,Freude T,Forst T,Nussler AK,Braun KF,Ehnert S

更新日期：2013-08-31 00:00:00

abstract：Background:There is lack of ideal and comprehensive economic evaluations of various GDM strategies. The aim of this study is to the compare efficacy and cost-effectiveness of five different methods of screening for gestational diabetes mellitus (GDM). Methods:This study is a randomized community non-inferiority trial ...

journal_title：Diabetology & metabolic syndrome

authors： Ramezani Tehrani F,Gulf Study Cooperative Research Group.

更新日期：2019-12-18 00:00:00

abstract：BACKGROUND:Coronary artery disease (CAD) is a major cardiovascular complication in diabetic patients. Despite the significant association between obesity and diabetes, the majority of the diabetic subjects are not obese in an Asian population. This study evaluated the association between obesity and coronary artery dis...

journal_title：Diabetology & metabolic syndrome

authors： Won KB,Chang HJ,Niinuma H,Sung J,Cho IJ,Shim CY,Hong GR,Kim YJ,Choi BW,Chung N

更新日期：2014-12-05 00:00:00

abstract：BACKGROUND:Polymorphisms in genes encoding adiponectin (ADIPOQ) and interleukin-6 (IL6) have been associated with adiposity and obese-related phenotypes. This study investigated the relationship of ADIPOQ and IL6 gene polymorphisms with pro-inflammatory and cardiometabolic markers in obese patients. METHODS:Anthropome...

journal_title：Diabetology & metabolic syndrome

authors： de Oliveira R,Moraes TI,Cerda A,Hirata MH,Fajardo CM,Sousa MC,Dorea EL,Bernik MM,Hirata RD

更新日期：2015-04-11 00:00:00

abstract：Background:Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with type 2 diabetes (T2DM). Carotid intima-media thickness (CIMT) is considered a preclinical stage of atherosclerosis. Therefore, it is necessary to identify the related risk factors for CIMT to facilitate the early pr...

journal_title：Diabetology & metabolic syndrome

authors： Zhou YY,Qiu HM,Yang Y,Han YY

更新日期：2020-01-28 00:00:00

abstract：BACKGROUND:Vildagliptin, a DPP-4 inhibitor widely used for the treatment of type 2 diabetes mellitus (T2DM), shows beneficial effects on endothelial function. This study aims to evaluate the effect of vildagliptin on endothelial function and arterial stiffness in patients with T2DM and hypertension. METHODS:Fifty over...

journal_title：Diabetology & metabolic syndrome

authors： Cosenso-Martin LN,Giollo-Júnior LT,Martineli DD,Cesarino CB,Nakazone MA,Cipullo JP,Vilela-Martin JF

更新日期：2015-08-26 00:00:00

abstract：Background:Whether polymorphisms in tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), interleukin-10 (IL-10) or adiponectin (ADIPOQ) influence the risk of gestational diabetes mellitus (GDM) or not remain inconclusive. Therefore, the authors conducted a meta-analysis to robustly assess relationships between polymo...

journal_title：Diabetology & metabolic syndrome

authors： Huang Q,Wang Y,Gu B,Xu Y

更新日期：2020-09-17 00:00:00

abstract：BACKGROUND:Patients with either diabetes mellitus (DM) or metabolic syndrome (MS) are recognized as a high risk group for cardiovascular disease (CVD). Several studies have demonstrated the clinical value of MS for predicting additional CVD risk in the DM population, although the clinical significance remains debatable...

journal_title：Diabetology & metabolic syndrome

authors： Rhee SY,Park SY,Hwang JK,Son JI,Chin SO,Kim YS,Woo JT

更新日期：2014-09-12 00:00:00

abstract：BACKGROUND:Diabetic retinopathy is the main cause of preventable blindness in the economically active population in western countries. Diabetic retinopathy screening is effective in preventing blindness and can be performed through various diagnostic methods. Our objective is to compare binocular indirect ophthalmoscop...

journal_title：Diabetology & metabolic syndrome

authors： Malerbi FK,Morales PH,Farah ME,Drummond KR,Mattos TC,Pinheiro AA,Mallmann F,Perez RV,Leal FS,Gomes MB,Dib SA,Brazilian Type 1 Diabetes Study Group.

更新日期：2015-12-21 00:00:00