Abstract:
BACKGROUND:Implantation of left atrial appendage (LAA) occlusion devices was shown to be a feasible and effective alternative to oral anticoagulation in patients with non-valvular atrial fibrillation. However, only few data about in-hospital and peri-procedural data are currently available. This study aims to report about echocardiographic, procedural and in-hospital data of patients receiving LAA occlusion devices. METHODS:This single-center, prospective and observational study includes consecutively patients being eligible for percutaneous implantation of LAA occlusion devices (either Watchman™ or Amplatzer™ Cardiac Plug 2). Data on pre- and peri-procedural transesophageal echocardiography (TEE), implantation and procedure related in-hospital complications were collected. The primary efficacy outcome measure was a successful device implantation without relevant peri-device leaks (i.e., < 5 mm). RESULTS:In total, 37 patients were included, 22 receiving the Watchman™ and 15 ACP 2 device. Baseline characteristics did not differ significantly in both patient groups. The primary efficacy outcome measure was reached in 91.9% of patients (90.9% for the Watchman™, 93.3 % for the ACP 2 group). One device embolization (Watchman™ group) with successful retrieval occurred (2.7% of patients). No thromboembolism or device thrombosis were present. The majority of bleedings was caused by access site bleedings (88.3% of all bleedings), consisting mostly of mild hematomas corresponding to a BARC type 1 bleeding (80.0% of all access-site complications). One patient died due to septic shock (non-procedure related). CONCLUSIONS:In daily real-life practice, percutaneous treatment with LAA occlusion devices appears to be an effective and safe.
journal_name
BMC Cardiovasc Disordjournal_title
BMC cardiovascular disordersauthors
Fastner C,Behnes M,Sartorius B,Yildiz M,Mashayekhi K,El-Battrawy I,Lehmann R,Baumann S,Becher T,Borggrefe M,Akin Idoi
10.1186/s12872-016-0200-zsubject
Has Abstractpub_date
2016-01-28 00:00:00pages
25issn
1471-2261pii
10.1186/s12872-016-0200-zjournal_volume
16pub_type
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