Is KCNH1 mutation related to coronary artery ectasia.

Abstract:

BACKGROUND:Coronary artery ectasia (CAE) is an uncommon finding in patients undergoing coronary angiography and acute myocardial infarction is an extremely uncommon condition in the presence of coronary artery ectasia. To date, 50 gene variants associated with coronary artery disease have been identified, but none appear to be related to coronary artery ectasia. CASE PRESENTATION:This is a rare case of Coronary artery ectasia which is considered to be related to Gene variations in potassium voltage-gated channel subfamily H member 1, KCNH1 (encoding a protein designated ether à go-go, EAG1 or KV10.1). CONCLUSION:Occurrence of Acute myocardial infarction in patient with coronary artery ectasia after diarrhea is a very rare condition and involvement of KCNH1 gene mutation which is described in this case report.

journal_name

BMC Cardiovasc Disord

authors

Noori MR,Zhang B,Pan L

doi

10.1186/s12872-019-01276-4

subject

Has Abstract

pub_date

2019-12-17 00:00:00

pages

296

issue

1

issn

1471-2261

pii

10.1186/s12872-019-01276-4

journal_volume

19

pub_type

  • Acute effects of using an electronic nicotine-delivery device (electronic cigarette) on myocardial function: comparison with the effects of regular cigarettes.

    abstract:BACKGROUND:Electronic cigarettes have been developed and marketed in recent years as smoking substitutes. However, no studies have evaluated their effects on the cardiovascular system. The purpose of this study was to examine the immediate effects of electronic cigarette use on left ventricular (LV) function, compared ...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-14-78

    authors: Farsalinos KE,Tsiapras D,Kyrzopoulos S,Savvopoulou M,Voudris V

    更新日期:2014-06-23 00:00:00

  • The relationship between mitral annular systolic velocity and ejection fraction in patients with preserved global systolic function of the left ventricle.

    abstract:BACKGROUND:The aim of the study was to investigate the relationship between the ejection fraction (EF) and the mitral annular systolic velocity (Sm) in patients with preserved left ventricular systolic function (EF>55%). The study task was to evaluate whether the assessment of Sm(avg) can be used as an alternative to t...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2261-13-92

    authors: Daskalov IR,Daskalova IK,Demirevska LD,Atzev BG

    更新日期:2013-10-26 00:00:00

  • Systematic review and meta-analysis of music interventions in hypertension treatment: a quest for answers.

    abstract:BACKGROUND:Adverse effects, treatment resistance and high costs associated with pharmacological treatment of hypertension have led to growing interest in non-pharmacological complementary therapies such as music interventions. This meta-analysis aims to provide an overview of reported evidence on the efficacy of music ...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,meta分析,评审

    doi:10.1186/s12872-016-0244-0

    authors: Kühlmann AY,Etnel JR,Roos-Hesselink JW,Jeekel J,Bogers AJ,Takkenberg JJ

    更新日期:2016-04-19 00:00:00

  • Prasugrel or ticagrelor relative to clopidogrel in triple-antiplatelet treatment combined with glycoprotein IIb/IIIa inhibitor for patients with STEMI undergoing PCI: a meta-analysis.

    abstract:BACKGROUND:For patients with ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI), the efficacy and safety of novel P2Y12 antagonists, including prasugrel or ticagrelor, has not been established relative to that of the clopidogrel-based triple-antiplatelet treatments (T...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,meta分析

    doi:10.1186/s12872-020-01403-6

    authors: Wang Z,Zhou DY,Su Y,Si LY,Xu Q

    更新日期:2020-03-12 00:00:00

  • Postoperative supraventricular tachycardia and polymorphic ventricular tachycardia due to a novel SCN5A variant: a case report of a rare comorbidity that is difficult to diagnose.

    abstract:BACKGROUND:Loss-of-function mutations of human cardiac sodium channel gene SCN5A induce a wide range of arrhythmic disorders. Mutation carriers with co-existing conditions such as congenital heart diseases and histories of cardiac surgeries, could develop complex arrhythmic events that are difficult to diagnose. CASE ...

    journal_title:BMC cardiovascular disorders

    pub_type:

    doi:10.1186/s12872-020-01601-2

    authors: Kato K,Ozawa T,Ohno S,Nakagawa Y,Horie M

    更新日期:2020-07-02 00:00:00

  • Outcome and quality of life after aorto-bifemoral bypass surgery.

    abstract:BACKGROUND:Aorto-bifemoral bypass (AFB) is commonly performed to treat aorto-iliac disease and a durable long-term outcome is achieved. Most studies documenting beneficial outcomes after AFB have been limited to mortality and morbidity rates, costs and length of hospital stay (LOS). Few studies have examined the depend...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-10-15

    authors: Abelha FJ,Botelho M,Fernandes V,Barros H

    更新日期:2010-03-18 00:00:00

  • The association between periodontal disease and the risk of myocardial infarction: a pooled analysis of observational studies.

    abstract:BACKGROUND:Several meta-analyses have indicated that periodontal disease (PD) are related to cardiovascular diseases (CVDs). However, the association between PD and myocardial infarction (MI) remains controversial. Here we aimed to assess the association between PD and MI by meta-analysis of observational studies. MET...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,meta分析,评审

    doi:10.1186/s12872-017-0480-y

    authors: Xu S,Song M,Xiong Y,Liu X,He Y,Qin Z

    更新日期:2017-02-01 00:00:00

  • Quantifying late gadolinium enhancement on CMR provides additional prognostic information in early risk-stratification of nonischemic cardiomyopathy: a cohort study.

    abstract:BACKGROUND:Suspected nonischemic cardiomyopathy (NICM) is a common clinical setting with highly variable prognosis. Early noninvasive risk-stratification is important for justification of invasive examinations, specific treatment and patient surveillance. We studied the additional prognostic value of late gadolinium en...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-14-110

    authors: Pöyhönen P,Kivistö S,Holmström M,Hänninen H

    更新日期:2014-08-27 00:00:00

  • Effects of Tolvaptan in patients with acute heart failure: a systematic review and meta-analysis.

    abstract:BACKGROUND:Acute heart failure, which requires urgent evaluation and treatment, is a leading cause for admission to the emergency department. The aim of this meta-analysis was to evaluate the effects of tolvaptan on acute heart failure and compare them with the effects of conventional therapy or placebo. METHODS:The e...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,meta分析,评审

    doi:10.1186/s12872-017-0598-y

    authors: Wang C,Xiong B,Cai L

    更新日期:2017-06-20 00:00:00

  • Mean platelet volume is associated with the presence of left atrial stasis in patients with non-valvular atrial fibrillation.

    abstract:BACKGROUND:Mean platelet volume has been associated with stroke in patients with atrial fibrillation. However, its role as a predictor of left atrial stasis, assessed by transesophageal echocardiography, in patients with non-valvular atrial fibrillation has not yet been clarified. METHODS:Single center cross-sectional...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-13-40

    authors: Providência R,Faustino A,Paiva L,Fernandes A,Barra S,Pimenta J,Trigo J,Botelho A,Leitão-Marques AM

    更新日期:2013-06-10 00:00:00

  • Important aspects in relation to patients' attendance at exercise-based cardiac rehabilitation - facilitators, barriers and physiotherapist's role: a qualitative study.

    abstract:BACKGROUND:In order to improve attendance at exercise-based cardiac rehabilitation (CR), a greater insight into patients' perspectives is necessary. The aim of the study was to explore aspects that influence patients' attendance at exercise-based CR after acute coronary artery disease (CAD) and the role of the physioth...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-017-0512-7

    authors: Bäck M,Öberg B,Krevers B

    更新日期:2017-03-14 00:00:00

  • Anomalous aortic origin of coronary arteries from the opposite sinus: a critical appraisal of risk.

    abstract:BACKGROUND:Anomalous aortic origin of the coronary artery (AAOCA) from the opposite sinus of Valsalva with an interarterial course has received much attention due to its association with sudden death in otherwise healthy individuals. AAOCA is relatively common and may have significant public health implications. While ...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,评审

    doi:10.1186/1471-2261-12-83

    authors: Peñalver JM,Mosca RS,Weitz D,Phoon CK

    更新日期:2012-10-01 00:00:00

  • Differences in metabolic profiles between bicuspid and tricuspid aortic stenosis in the setting of transcatheter aortic valve replacement.

    abstract:BACKGROUND:To explore why bicuspid aortic stenosis has certain clinical differences from the tricuspid morphology, we evaluated the metabolomics profile involved in bicuspid aortic valve (BAV) aortic stenosis prior to and after transcatheter aortic valve replacement (TAVR) in comparison with tricuspid aortic valve (TAV...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-020-01491-4

    authors: Xiong TY,Liu C,Liao YB,Zheng W,Li YJ,Li X,Ou Y,Wang ZJ,Wang X,Li CM,Zhao ZG,Feng Y,Liu XJ,Chen M

    更新日期:2020-05-18 00:00:00

  • Differing effects of beta-blockers on long-term clinical outcomes following percutaneous coronary intervention between patients with mid-range and reduced left ventricular ejection fraction.

    abstract:BACKGROUND:The aim of this study was to determine the difference in effects of beta-blockers on long-term clinical outcomes between ischemic heart disease (IHD) patients with mid-range ejection fraction (mrEF) and those with reduced ejection fraction (rEF). METHODS:Data were assessed of 3508 consecutive IHD patients w...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-021-01850-9

    authors: Shitara J,Naito R,Kasai T,Endo H,Wada H,Doi S,Konishi H,Tsuboi S,Ogita M,Dohi T,Okazaki S,Miyauchi K,Daida H

    更新日期:2021-01-15 00:00:00

  • The relation between neutrophil-to-lymphocyte ratio and coronary chronic total occlusions.

    abstract:BACKGROUND:Neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that correlates with cardiac events. This study assessed the association between NLR and the presence of chronic coronary total occlusion (CTO). METHODS:The study population included 225 patients, a control group (n = 75), a coronary ...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-14-130

    authors: Demir K,Avci A,Altunkeser BB,Yilmaz A,Keles F,Ersecgin A

    更新日期:2014-09-27 00:00:00

  • Idiopathic premature ventricular contractions and ventricular tachycardias originating from the vicinity of tricuspid annulus: results of radiofrequency catheter ablation in thirty-five patients.

    abstract:BACKGROUND:In recent years, catheter ablation has increasingly been used for ablation of idiopathic premature ventricular complexes (PVCs) or ventricular tachycardias (IVTs). However, the mapping and catheter ablation of the arrhythmias originating from the vicinity of tricuspid annulus (TA) may not be fully understood...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-12-32

    authors: Yue-Chun L,Wen-Wu Z,Na-Dan Z,Teng Z,Pin-Xiao W,Bei G,Jia L,Kang-Ting J,Jia-Feng L

    更新日期:2012-07-10 00:00:00

  • High platelet reactivity affects the clinical outcomes of patients undergoing percutaneous coronary intervention.

    abstract:BACKGROUND:The association of platelet reactivity and clinical outcomes, especially stent thrombosis, was not so clear. We sought to investigate whether high platelet reactivity affects clinical outcomes of patients with drug eluting stents (DESs) implantation. METHODS:All enrolled individuals treated with DESs implan...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-016-0394-0

    authors: Zhang JJ,Gao XF,Ge Z,Tian NL,Liu ZZ,Lin S,Ye F,Chen SL

    更新日期:2016-11-29 00:00:00

  • Associations between hyperhomocysteinemia and the presence and severity of acute coronary syndrome in young adults ≤ 35 years of age.

    abstract:BACKGROUND:The prevalence of acute coronary syndrome (ACS) continues to increase among young Chinese adults. Homocysteine (HCY) has been suggested as a promoter of atherosclerosis leading to coronary artery disease (CAD). Yet, it remains uncertain whether HCY is associated with the ACS and the severity of coronary arte...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-021-01869-y

    authors: Sun J,Han W,Wu S,Jia S,Yan Z,Guo Y,Zhao Y,Zhou Y,Liu W

    更新日期:2021-01-23 00:00:00

  • Aortic stenosis and mitral regurgitation as predictors of atrial fibrillation during 11 years of follow-up.

    abstract:BACKGROUND:There is limited information about any association between the onset of atrial fibrillation (AF) and the presence of valvular disease. METHODS:We retrospectively examined 940 patients in sinus rhythm, examined by echocardiography in 1996. During 11 years of follow-up, we assessed the incidence of AF and out...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-12-92

    authors: Widgren V,Dencker M,Juhlin T,Platonov P,Willenheimer R

    更新日期:2012-10-18 00:00:00

  • Atrial matrix remodeling in atrial fibrillation patients with aortic stenosis.

    abstract:BACKGROUND:This study aimed to evaluate atrium extracellular matrix remodeling in atrial fibrillation (AF) patients with severe aortic stenosis, through histological fibrosis quantification and extracellular matrix gene expression analysis, as well as serum quantification of selected protein targets. METHODS:A posthoc...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-020-01754-0

    authors: Fragão-Marques M,Miranda I,Martins D,Barroso I,Mendes C,Pereira-Neves A,Falcão-Pires I,Leite-Moreira A

    更新日期:2020-10-31 00:00:00

  • Genetic and ElectroNic medIcal records to predict oUtcomeS in Heart Failure patients (GENIUS-HF) - design and rationale.

    abstract:BACKGROUND:Studies adopting electronic medical records and genomic information are becoming widespread. Through this new modality in research, it is possible to study how genetic variants influence susceptibility towards chronic conditions and can improve patient care.Our aim is to develop a biobank with 2,000 heart fa...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-14-32

    authors: Gioli-Pereira L,Bernardez-Pereira S,Goulart Marcondes-Braga F,Rocha Spina JM,Muniz Miranda da Silva R,Evangelista Ferreira N,Bacal F,Fernandes F,Mansur AJ,Krieger JE,Costa Pereira A

    更新日期:2014-03-04 00:00:00

  • Mortality and morbidity trends after the first year in survivors of acute myocardial infarction: a systematic review.

    abstract:BACKGROUND:Most studies of outcomes after myocardial infarction (MI) focus on the acute phase after the index event. We assessed mortality and morbidity trends after the first year in survivors of acute MI, by conducting a systematic literature review. METHODS:Literature searches were conducted in Embase, MEDLINE, and...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,评审

    doi:10.1186/s12872-017-0482-9

    authors: Johansson S,Rosengren A,Young K,Jennings E

    更新日期:2017-02-07 00:00:00

  • Influence of smoking cessation drugs on blood pressure and heart rate in patients with cardiovascular disease or high risk score: real life setting.

    abstract:BACKGROUND:Smoking is the most important reversible cardiovascular risk factor. It is well established that quitting smoking reduces coronary events. However, on several occasions, the cardiovascular safety of smoking cessation drugs has been questioned. Our goal is to evaluate the effects of smoking cessation drugs on...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-015-0180-4

    authors: Silva AP,Scholz J,Abe TO,Pinheiro GG,Gaya PV,Pereira AC,Santos PC

    更新日期:2016-01-05 00:00:00

  • The association between processes, structures and outcomes of secondary prevention care among VA ischemic heart disease patients.

    abstract:BACKGROUND:Hyperlipidemia and hypertension are well-established risk factors for recurrent cardiovascular events among patients with ischemic heart disease (IHD). Despite national recommendations, concordance with guidelines for LDL cholesterol and blood pressure remains inadequate. The objectives of this study were to...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-6-6

    authors: Ho PM,Prochazka AV,Magid DJ,Sales AE,Grunwald GK,Hammermeister KE,Rumsfeld JS

    更新日期:2006-02-09 00:00:00

  • Prevalence of heart failure in Australia: a systematic review.

    abstract:BACKGROUND:In the absence of a systematic collection of data pertaining to heart failure, summarizing the data available from individual studies provides an opportunity to estimate the burden of heart failure. The present study systematically reviewed the literature to estimate the incidence and prevalence rates of hea...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,评审

    doi:10.1186/s12872-016-0208-4

    authors: Sahle BW,Owen AJ,Mutowo MP,Krum H,Reid CM

    更新日期:2016-02-06 00:00:00

  • Late discovery of left atrial appendage occluder device embolization: a case report.

    abstract:BACKGROUND:Left atrial appendage (LAA) closure has been well evaluated in the prevention of stroke in patients with atrial fibrillation. Device embolization remains one of the most common complications. To the best of our knowledge, there have been no reports of late discovery of LAA occluder device embolization at 1.5...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,评审

    doi:10.1186/s12872-020-01589-9

    authors: Mansour MJ,Bénic C,Didier R,Noel A,Gilard M,Mansourati J

    更新日期:2020-06-22 00:00:00

  • Loss of ectonucleotidases from the coronary vascular bed after ischemia-reperfusion in isolated rat heart.

    abstract:BACKGROUND:Ectonucleotidase plays an important role in the regulation of cardiac function by controlling extracellular levels of adenine nucleotides and adenosine. To determine the influence of ischemia-reperfusion injury on ectonucleotidase activity in coronary vascular bed, we compared the metabolic profile of adenin...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-13-53

    authors: Takahashi-Sato K,Murakawa M,Kimura J,Ito MA,Matsuoka I

    更新日期:2013-07-28 00:00:00

  • β-blockers and risk of all-cause mortality in patients with chronic heart failure and atrial fibrillation-a meta-analysis.

    abstract:BACKGROUND:Effects of β-blockers on outcomes in patients with chronic heart failure (CHF) and atrial fibrillation (AF) is still in controversy. METHODS:Searching was conducted by using keywords "atrial fibrillation", and "heart failure" in PubMed, MEDLINE and Embase databases before November 30, 2017. Prospective stud...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,meta分析

    doi:10.1186/s12872-019-1079-2

    authors: Xu T,Huang Y,Zhou H,Bai Y,Huang X,Hu Y,Xu D,Zhang Y,Zhang J

    更新日期:2019-06-03 00:00:00

  • Up-regulating autophagy by targeting the mTOR-4EBP1 pathway: a possible mechanism for improving cardiac function in mice with experimental dilated cardiomyopathy.

    abstract:BACKGROUND:Autophagy plays a crucial role in the pathological process of cardiovascular diseases. However, little is known about the pathological mechanism underlying autophagy regulation in dilated cardiomyopathy (DCM). METHODS:We explored whether up-regulating autophagy could improve cardiac function in mice with ex...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-020-01365-9

    authors: Jin B,Shi H,Zhu J,Wu B,Geshang Q

    更新日期:2020-02-04 00:00:00

  • The association between Matrix Metallo-proteinases-9 (MMP-9) gene family polymorphisms and risk of Coronary Artery Disease (CAD): a systematic review and meta-analysis.

    abstract:BACKGROUND:We performed a systematic review and meta-analysis of the Matrix metalloproteinases (MMP)-9 (C1562T), MMP-9 (R279Q), MMP-9 (P574R) and MMP-9 (R668Q) polymorphisms and risk of Coronary Artery Disease (CAD). METHODS:After a systematic literature search, pooled odds ratio (OR) and their corresponding 95% confi...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,meta分析

    doi:10.1186/s12872-020-01510-4

    authors: Hassanzadeh-Makoui R,Razi B,Aslani S,Imani D,Tabaee SS

    更新日期:2020-05-19 00:00:00