The relation between neutrophil-to-lymphocyte ratio and coronary chronic total occlusions.

Abstract:

BACKGROUND:Neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that correlates with cardiac events. This study assessed the association between NLR and the presence of chronic coronary total occlusion (CTO). METHODS:The study population included 225 patients, a control group (n = 75), a coronary artery disease group (n = 75), and a CTO group (n = 75). NLR was compared in the three groups. RESULTS:NLR levels were significantly higher in the CTO than in the other two groups (p < 0.001). Bivariate correlation analysis showed a positive correlation between NLR and SYNTAX Score, and multivariate logistic regression analysis found that NLR was an independent predictor of CTO. ROC analysis showed that an NLR cut-off of 2.09 could distinguish between patients with and without CTO (AUC = 0.74; 95% CI, 0.68-0.81), with a specificity of 69.3% and a sensitivity of 61%. CONCLUSION:NLR may be useful as a marker of CTO.

journal_name

BMC Cardiovasc Disord

authors

Demir K,Avci A,Altunkeser BB,Yilmaz A,Keles F,Ersecgin A

doi

10.1186/1471-2261-14-130

subject

Has Abstract

pub_date

2014-09-27 00:00:00

pages

130

issn

1471-2261

pii

1471-2261-14-130

journal_volume

14

pub_type

杂志文章