Abstract:
BACKGROUND:Intravascular ultrasound (IVUS) can be a useful tool during drug-eluting stents (DES) implantation as it allows accurate assessment of lesion severity and optimal treatment planning. However, numerous reports have shown that IVUS guided percutaneous coronary intervention is not associated with improved clinical outcomes, especially in non-complex patients and lesions. METHODS:We searched the literature in Medline, the Cochrane Library, and other internet sources to identify studies that compare clinical outcomes between IVUS-guided and angiography-guided DES implantation. Random-effects model was used to assess treatment effect. RESULTS:Twenty eligible studies with a total of 29,068 patients were included in this meta-analysis. The use of IVUS was associated with significant reductions in major adverse cardiovascular events (MACE, odds ratios [OR] 0.77, 95 % confidence intervals [CI] 0.71-0.83, P < 0.001), death (OR 0.62, 95 % CI 0.54-0.71, p < 0.001), and stent thrombosis (OR 0.59, 95 % CI: 0.47-0.73, P < 0.001). The benefit was also seen in the repeated analysis of matched and randomized studies. In stratified analysis, IVUS guidance appeared to be beneficial not only in patients with complex lesions or acute coronary syndromes (ACS) but also patients with mixed lesions or presentations (MACE: OR 0.69, 95 % CI: 0.60-0.79, p < 0.001, OR 0.81, 95 % CI 0.74-0.90, p < 0.001, respectively). By employing meta-regression analysis, the benefit of IVUS is significantly pronounced in patients with complex lesions or ACS with respect to death (p = 0.048). CONCLUSIONS:IVUS guidance was associated with improved clinical outcomes, especially in patients with complex lesions admitted with ACS. Large, randomized clinical trials are warranted to identify populations and lesion characteristics where IVUS guidance would be associated with better outcomes.
journal_name
BMC Cardiovasc Disordjournal_title
BMC cardiovascular disordersauthors
Zhang YJ,Pang S,Chen XY,Bourantas CV,Pan DR,Dong SJ,Wu W,Ren XM,Zhu H,Shi SY,Iqbal J,Gogas BD,Xu B,Chen SLdoi
10.1186/s12872-015-0144-8subject
Has Abstractpub_date
2015-11-17 00:00:00pages
153issn
1471-2261pii
10.1186/s12872-015-0144-8journal_volume
15pub_type
杂志文章,meta分析,评审abstract:BACKGROUND:Early detection of heart failure is essential to effectively reduce related mortality. The quantification of the mechanical properties of the myocardium, a primordial indicator of the viability of the cardiac tissue, is a key element in patient's care. Despite an incremental utilization of multi-parametric m...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/1471-2261-13-24
更新日期:2013-03-27 00:00:00
abstract:BACKGROUND:Previous renal denervation (RDN) studies showed controversial results in reducing blood pressure. The aim of this study was to provide evidence supporting the effectiveness of laparoscopic-based renal denervation (L-RDN) in treating hypertension. METHODS:Sixteen Beagle dogs were randomly divided into RDN gr...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-020-01546-6
更新日期:2020-06-11 00:00:00
abstract:BACKGROUND:Adiponectin is a biomarker that is associated with type 2 diabetes and hypertension. Lower circulating level is a risk factor. Higher levels are protective. African Americans have a higher prevalence of type 2 diabetes and hypertension and lower levels of adiponectin when compared to other racial/ethnic grou...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-015-0005-5
更新日期:2015-02-25 00:00:00
abstract:BACKGROUND:The growing population of cancer survivors and their high frequency of cardiovascular disease have resulted in a dramatic increase in cancer patients requiring cardiovascular intervention. However, there is a lack of evidence to guide optimal management in this complex population who have historically been e...
journal_title:BMC cardiovascular disorders
pub_type: 评论,杂志文章
doi:10.1186/s12872-020-01539-5
更新日期:2020-05-27 00:00:00
abstract:BACKGROUND:Ectonucleotidase plays an important role in the regulation of cardiac function by controlling extracellular levels of adenine nucleotides and adenosine. To determine the influence of ischemia-reperfusion injury on ectonucleotidase activity in coronary vascular bed, we compared the metabolic profile of adenin...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/1471-2261-13-53
更新日期:2013-07-28 00:00:00
abstract:BACKGROUND:For patients with ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI), the efficacy and safety of novel P2Y12 antagonists, including prasugrel or ticagrelor, has not been established relative to that of the clopidogrel-based triple-antiplatelet treatments (T...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章,meta分析
doi:10.1186/s12872-020-01403-6
更新日期:2020-03-12 00:00:00
abstract:BACKGROUND:Risk stratification is recommended as the key step to prevent contrast-associated acute kidney injury (CA-AKI) among at-risk patients following coronary angiography (CAG) and/or percutaneous coronary intervention (PCI). Patients with hypoalbuminemia are prone to CA-AKI and do not have their own risk stratifi...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-020-01689-6
更新日期:2020-08-31 00:00:00
abstract:BACKGROUND:Neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that correlates with cardiac events. This study assessed the association between NLR and the presence of chronic coronary total occlusion (CTO). METHODS:The study population included 225 patients, a control group (n = 75), a coronary ...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/1471-2261-14-130
更新日期:2014-09-27 00:00:00
abstract:BACKGROUND:Smooth muscle cells play an important role in the development of atherosclerosis. SHP2 is known to regulate the proliferation and migration of smooth muscle cells. The purpose of this study was to determine whether the SHP2 inhibitor PHPS1 has a pro-atherosclerotic or an atheroprotective effect in vivo and i...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-018-0816-2
更新日期:2018-04-27 00:00:00
abstract:BACKGROUND:Psoriasis is an inflammatory disease associated with increased risk of coronary artery disease. However, the potential impact of psoriasis on the prognosis following percutaneous coronary revascularization (PCI) is unknown. METHODS:The study comprised the entire Danish population undergoing first-time PCI i...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/1471-2261-12-79
更新日期:2012-09-24 00:00:00
abstract:BACKGROUND:In the absence of a systematic collection of data pertaining to heart failure, summarizing the data available from individual studies provides an opportunity to estimate the burden of heart failure. The present study systematically reviewed the literature to estimate the incidence and prevalence rates of hea...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章,评审
doi:10.1186/s12872-016-0208-4
更新日期:2016-02-06 00:00:00
abstract:BACKGROUND:Reported effects of obesity on the extent of angiographic coronary artery disease(CAD) have been inconsistent. The present study aimed to investigate the relationships between the indices of obesity and other anthropometric markers with the extent of CAD. METHODS:This study was conducted on 1008 consecutive...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-020-01534-w
更新日期:2020-05-29 00:00:00
abstract:BACKGROUND:Periostin, an extracellular matrix protein, plays a significant role in adverse cardiac remodeling. However, no report has documented the function of periostin in left ventricular remodeling of streptozototin (STZ)-induced diabetic rats. The aim of the present study was to observe the expression of periostin...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-015-0084-3
更新日期:2015-08-18 00:00:00
abstract:BACKGROUND:Cigarette smoking is a leading cause of mortality and morbidity and is associated with cardiovascular disease via contributory processes such as endothelial dysfunction, inflammation and thrombosis. Cigarette smoke both contains and stimulates the production of cellular oxidants and it may also promote vascu...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2261-12-75
更新日期:2012-09-17 00:00:00
abstract:BACKGROUND:The rational length of stay following non-complicated percutaneous coronary intervention (PCI) for Non-ST elevation myocardial infarction (NSTEMI) patients remains controversial. Few studies have examined the impact of early discharge on short-term outcomes in NSTEMI patients, but short-time discharge is not...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-019-1096-1
更新日期:2019-05-14 00:00:00
abstract:BACKGROUND:Epicardial adipose tissue (EAT) remodeling and adipocytokines are associated with structural remodeling in atrial fibrillation (AF). However, the role of omentin-1, a novel adipocytokine, in structural remodeling remains unknown. METHODS:Hematoxylin and eosin (H&E) and Masson's trichrome stains were used to...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-020-01478-1
更新日期:2020-05-06 00:00:00
abstract:BACKGROUND:ST elevation Myocardial infarction is a medical emergency. A variety of noncardiac conditions had been known to mimic the ECG changes that are seen in acute coronary syndrome. Although the common ECG changes that are documented with raised intracranial pressure are T inversions, prolongation of QT interval a...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-017-0525-2
更新日期:2017-04-04 00:00:00
abstract:BACKGROUND:We investigated the association between heart rate and its variability with the parameters that assess vascular, renal and cardiac target organ damage. METHODS:A cross-sectional study was performed including a consecutive sample of 360 hypertensive patients without heart rate lowering drugs (aged 56 ± 11 ye...
journal_title:BMC cardiovascular disorders
pub_type: 临床试验,杂志文章
doi:10.1186/1471-2261-12-19
更新日期:2012-03-22 00:00:00
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journal_title:BMC cardiovascular disorders
pub_type: 杂志文章,meta分析
doi:10.1186/s12872-018-0881-6
更新日期:2018-07-11 00:00:00
abstract:BACKGROUND:Mean platelet volume has been associated with stroke in patients with atrial fibrillation. However, its role as a predictor of left atrial stasis, assessed by transesophageal echocardiography, in patients with non-valvular atrial fibrillation has not yet been clarified. METHODS:Single center cross-sectional...
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pub_type: 杂志文章
doi:10.1186/1471-2261-13-40
更新日期:2013-06-10 00:00:00
abstract:BACKGROUND:Smoking is the most important reversible cardiovascular risk factor. It is well established that quitting smoking reduces coronary events. However, on several occasions, the cardiovascular safety of smoking cessation drugs has been questioned. Our goal is to evaluate the effects of smoking cessation drugs on...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-015-0180-4
更新日期:2016-01-05 00:00:00
abstract:BACKGROUND:Despite the potentially life-saving benefits of the implantable cardioverter-defibrillator (ICD), a significant group of patients experiences emotional distress after ICD implantation. Different psychosocial interventions have been employed to improve this condition, but previous reviews have suggested that ...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章,评审
doi:10.1186/1471-2261-9-56
更新日期:2009-12-29 00:00:00
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journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-016-0215-5
更新日期:2016-02-17 00:00:00
abstract:BACKGROUND:Angiography is a highly effective invasive method for diagnosing coronary artery diseases but can lead to certain psychological problems such as stress, anxiety, and depression. This study aimed to compare the effects of education delivery through multimedia DVD content or text messaging in comparison with c...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-020-01820-7
更新日期:2021-01-04 00:00:00
abstract:BACKGROUND:Cigarette exposure increases brain oxidative stress. The literature showed that increased brain oxidative stress affects cardiovascular regulation. However, no previous study investigated the involvement of brain oxidative stress in animals exposed to cigarette and its relationship with cardiovascular regula...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/1471-2261-12-22
更新日期:2012-03-30 00:00:00
abstract:BACKGROUND:Long term β-blocker therapy after myocardial infarction (MI) reduces mortality and recurrent MI but evidence for this treatment predates contemporary acute coronary care. β-blocker treatment is a key quality of care indicator in the Swedish national quality register for acute coronary care, Riks-HIA. Between...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-020-01441-0
更新日期:2020-04-09 00:00:00
abstract:BACKGROUND:Ticagrelor and clopidogrel, P2Y12 receptor antagonists, can prevent thrombotic events and are used to treat cardiovascular diseases such as acute coronary syndrome and chronic obstructive pulmonary disease, in which inflammation is involved. Moreover, NF-B is the central regulator of inflammation. Thus, we s...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-019-01287-1
更新日期:2019-12-30 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate the predictive value of cystatin C (CysC) and estimated glomerular filtration rate (eGFR) regarding vascular lesions and their severity in patients with acute coronary syndrome (ACS). METHODS:According to the results of coronary angiography, 195 ACS patients were divide...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-017-0483-8
更新日期:2017-01-31 00:00:00
abstract:BACKGROUND:Systemic inflammation is an important feature of post-cardiac arrest syndrome (PCAS). This study was designed to determine whether the plasma concentrations of some circulating pro-inflammatory cytokines (interleukin-17 [IL-8], IL-22, IL-23 and IL-33) are of value in predicting the outcome of patients after ...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-020-01451-y
更新日期:2020-04-15 00:00:00
abstract:BACKGROUND:A number of registry studies have reported suboptimal adherence to guidelines for cardiovascular prevention during the first year after acute myocardial infarction (AMI). However, only a few studies have addressed long-term secondary prevention after AMI. This study evaluates prevention guideline adherence a...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-016-0400-6
更新日期:2016-11-17 00:00:00