Ischaemic heart disease and Cancer: competing malignant conditions.

Abstract:

BACKGROUND:The growing population of cancer survivors and their high frequency of cardiovascular disease have resulted in a dramatic increase in cancer patients requiring cardiovascular intervention. However, there is a lack of evidence to guide optimal management in this complex population who have historically been excluded from cardiovascular trials. DISCUSSION:We review the recently published meta-analysis by Roule et al. The findings of this analysis demonstrate that patients with cancer presenting with acute coronary syndrome (ACS) have increased rates of in-hospital cardiovascular mortality, bleeding and one-year cardiovascular mortality. All-cause mortality measured in-hospital and at one-year were also significantly greater in cancer patients as was all-cause mortality in cancer patients that undergo percutaneous coronary intervention (PCI). In contrast to the short-term outcomes, rates of long-term cardiovascular mortality did not differ significantly between groups. Patient-specific assessment of risk, accounting for disease characteristics and treatment, and close communication with oncology providers is vital in defining optimal treatment strategies in this population.

journal_name

BMC Cardiovasc Disord

authors

Murphy AC,Koshy AN,Yudi MB

doi

10.1186/s12872-020-01539-5

subject

Has Abstract

pub_date

2020-05-27 00:00:00

pages

254

issue

1

issn

1471-2261

pii

10.1186/s12872-020-01539-5

journal_volume

20

pub_type

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