The lack of clinical value of peritoneal washing cytology in high risk patients undergoing risk-reducing salpingo-oophorectomy: a retrospective study and review.

abstract：BACKGROUND:The mixture of volatile organic compounds in the headspace gas of urine may be able to distinguish lung cancer patients from relevant control populations. METHODS:Subjects with biopsy confirmed untreated lung cancer, and others at risk for developing lung cancer, provided a urine sample. A colorimetric sens...

journal_title：BMC cancer

authors： Mazzone PJ,Wang XF,Lim S,Choi H,Jett J,Vachani A,Zhang Q,Beukemann M,Seeley M,Martino R,Rhodes P

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:In a recent pilot report, we showed that Smac/DIABLO mRNA is expressed de novo in a subset of cervical cancer patients. We have now expanded this study and analyzed Smac/DIABLO expression in the primary lesions in 109 cervical cancer patients. METHODS:We used immunohistochemistry of formalin-fixed, paraffin...

journal_title：BMC cancer

authors： Arellano-Llamas A,Garcia FJ,Perez D,Cantu D,Espinosa M,De la Garza JG,Maldonado V,Melendez-Zajgla J

更新日期：2006-10-26 00:00:00

abstract：BACKGROUND:Little information is available concerning how patient delay may be affected by mass disasters. The main objectives of the present study are to identify whether there was a post-disaster increase in the risk of experiencing patient delay among breast cancer patients in an area affected by the 2011 triple dis...

journal_title：BMC cancer

authors： Ozaki A,Nomura S,Leppold C,Tsubokura M,Tanimoto T,Yokota T,Saji S,Sawano T,Tsukada M,Morita T,Ochi S,Kato S,Kami M,Nemoto T,Kanazawa Y,Ohira H

更新日期：2017-06-19 00:00:00

abstract：BACKGROUND:Pancreas ductal adenocarcinoma (PDAC) has the most dismal prognosis among all human cancers since it is highly resistant to chemotherapy, radiotherapy and immunotherapy. The anticipated consequence of all therapies is induction of tumor apoptosis. The highly resistance nature of PDACs to all therapies sugges...

journal_title：BMC cancer

authors： Lu C,Yang D,Sabbatini ME,Colby AH,Grinstaff MW,Oberlies NH,Pearce C,Liu K

更新日期：2018-02-06 00:00:00

abstract：BACKGROUND:Radiation-induced parotid damage is one of the most common complications in patients with nasopharyngeal carcinoma (NPC) undergoing radiotherapy (RT). Intravoxel incoherent motion (IVIM) magnetic resonance (MR) imaging has been reported for evaluating irradiated parotid damage. However, the changes of IVIM p...

journal_title：BMC cancer

authors： Zhou N,Chu C,Dou X,Li M,Liu S,Zhu L,Liu B,Guo T,Chen W,He J,Yan J,Zhou Z,Yang X,Liu T

更新日期：2016-11-08 00:00:00

abstract：BACKGROUND:Racial disparities are well-documented in preventive cancer care, but they have not been fully explored in the context of lung cancer screening. We sought to explore racial differences in lung cancer screening outcomes within a lung cancer screening program (LCSP) at our urban academic medical center includi...

journal_title：BMC cancer

authors： Lake M,Shusted CS,Juon HS,McIntire RK,Zeigler-Johnson C,Evans NR,Kane GC,Barta JA

更新日期：2020-06-16 00:00:00

abstract：BACKGROUND:The 3rd isoform of the metallothionein (MT3) gene family has been shown to be overexpressed in most ductal breast cancers. A previous study has shown that the stable transfection of MCF-7 cells with the MT3 gene inhibits cell growth. The goal of the present study was to determine the role of the unique C-ter...

journal_title：BMC cancer

authors： Voels B,Wang L,Sens DA,Garrett SH,Zhang K,Somji S

更新日期：2017-05-25 00:00:00

abstract：BACKGROUND:The glycosylphosphatidylinositol-anchored extracellular membrane serine protease prostasin is expressed in normal bladder urothelial cells. Bladder inflammation reduces prostasin expression and a loss of prostasin expression is associated with epithelial-mesenchymal transition (EMT) in human bladder transiti...

journal_title：BMC cancer

authors： Chai AC,Robinson AL,Chai KX,Chen LM

更新日期：2015-12-29 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate epigenetic status of cyclin A1 in human papillomavirus-associated cervical cancer. Y. Tokumaru et al., Cancer Res 64, 5982-7 (Sep 1, 2004)demonstrated in head and neck squamous-cell cancer an inverse correlation between cyclin A1 promoter hypermethylation and TP53 mutati...

journal_title：BMC cancer

authors： Kitkumthorn N,Yanatatsanajit P,Kiatpongsan S,Phokaew C,Triratanachat S,Trivijitsilp P,Termrungruanglert W,Tresukosol D,Niruthisard S,Mutirangura A

更新日期：2006-03-08 00:00:00

abstract：BACKGROUND:Socioeconomic inequalities in cancer mortality in Britain have been shown to be present in the 1990s and early 2000s. Little is known about on-going patterns in such inequalities in cancer mortality. We examined time trends in socioeconomic inequalities in cancer mortality in Britain between 1978 and 2013. ...

journal_title：BMC cancer

authors： Ramsay SE,Morris RW,Whincup PH,Papacosta AO,Lennon LT,Wannamethee SG

更新日期：2014-06-30 00:00:00

abstract：BACKGROUND:The immune system plays an important role in the multifactorial biologic system during the development of neoplasias. However, the involvement of the inflammatory response in the promotion/control of malignant cells is still controversial, and the cell subsets and the mechanisms involved are poorly investiga...

journal_title：BMC cancer

authors： Estrela-Lima A,Araújo MS,Costa-Neto JM,Teixeira-Carvalho A,Barrouin-Melo SM,Cardoso SV,Martins-Filho OA,Serakides R,Cassali GD

更新日期：2010-06-04 00:00:00

abstract：BACKGROUND:Free flap-mediated gene therapy in the tumor bed following surgical resection is a promising approach in cancer targeted treatment of residual disease. We investigated the selective killing efficacy of a lentivirus-mediated cytosine deaminase-thymidine kinase (CDglyTK) gene in transplanted breast cancer deli...

journal_title：BMC cancer

authors： Zhang J,Liu Y,Zang M,Zhu S,Chen B,Li S,Xue B,Yan L

更新日期：2019-09-14 00:00:00

abstract：BACKGROUND:It is urgent to find some biochemical markers for predicting the radiochemotherapy sensitivity. microRNAs have a huge potential as a predictive biomarker in gastric cancer. The current study aims to identify the microRNAs related to the radiochemotherapy sensitivity in gastric cancer. METHODS:From April 201...

journal_title：BMC cancer

authors： Liu X,Cai H,Sheng W,Huang H,Long Z,Wang Y

更新日期：2018-10-29 00:00:00

abstract：BACKGROUND:Compared with World Health Organization-defined acute myeloid leukaemia (AML) not otherwise specified, patients with AML with myelodysplasia-related changes (AML-MRC) are generally older and more likely to have poor-risk cytogenetics, leading to poor response and prognosis. More than one-half of all older (≥...

journal_title：BMC cancer

authors： Seymour JF,Döhner H,Butrym A,Wierzbowska A,Selleslag D,Jang JH,Kumar R,Cavenagh J,Schuh AC,Candoni A,Récher C,Sandhu I,Del Castillo TB,Al-Ali HK,Falantes J,Stone RM,Minden MD,Weaver J,Songer S,Beach CL,Dombret H

更新日期：2017-12-14 00:00:00

abstract：BACKGROUND:It is well known that women suffer from negative consequences following breast cancer (BC) treatment and that their largely varying needs for rehabilitation are often unmet. Up to 43% of these women are at risk of developing chronic distress requiring complex interventions; however, how to early identify and...

journal_title：BMC cancer

authors： Olsson Möller U,Rydén L,Malmström M

更新日期：2020-05-29 00:00:00

abstract：BACKGROUND:Currently there are very few biomarkers to identify head and neck squamous cell carcinoma (HNSCC) cancer patients at a greater risk of recurrence and shortened survival. This study aimed to investigate whether a marker of systemic inflammation, the neutrophil-to-lymphocyte ratio (NLR), was predictive of clin...

journal_title：BMC cancer

authors： Charles KA,Harris BD,Haddad CR,Clarke SJ,Guminski A,Stevens M,Dodds T,Gill AJ,Back M,Veivers D,Eade T

更新日期：2016-02-18 00:00:00

abstract：BACKGROUND:Venous thromboembolic events (VTE) are common in cancer patients and associated with higher mortality. In vivo thrombosis and anticoagulation might be involved in tumor growth and progression. We studied the association of warfarin and other anticoagulant use as antithrombotic medication and prostate cancer ...

journal_title：BMC cancer

authors： Kinnunen PTT,Murtola TJ,Talala K,Taari K,Tammela TLJ,Auvinen A

更新日期：2017-08-29 00:00:00

abstract：BACKGROUND:This study is designed to investigate the clinical value of systemic chemotherapy combined with bronchoscopic interventional cryotherapy in the treatment of lung cancer. METHODS:A total of 412 lung cancer patients admitted to Cangzhou People's Hospital from March 2018 to March 2020 were collected and divide...

journal_title：BMC cancer

authors： Xu F,Song J,Xu B,Wang J,Mao J,Liu H,Li X,Deng A

更新日期：2020-11-11 00:00:00

abstract：BACKGROUND:Pancreatic ductal adenocarcinoma (PDAC) is considered as one of the most aggressive cancers lacking efficient early detection biomarkers. Circulating miRNAs are now being considered to have potency to be used as diagnostic and prognostic biomarkers in different diseases as well as cancers. In case of cancer,...

journal_title：BMC cancer

authors： Chhatriya B,Mukherjee M,Ray S,Sarkar P,Chatterjee S,Nath D,Das K,Goswami S

更新日期：2019-12-03 00:00:00

abstract：BACKGROUND:Axonal sensory peripheral neuropathy is the major dose-limiting side effect of paclitaxel.Omega-3 fatty acids have beneficial effects on neurological disorders from their effects on neurons cells and inhibition of the formation of proinflammatory cytokines involved in peripheral neuropathy. METHODS:This stu...

journal_title：BMC cancer

authors： Ghoreishi Z,Esfahani A,Djazayeri A,Djalali M,Golestan B,Ayromlou H,Hashemzade S,Asghari Jafarabadi M,Montazeri V,Keshavarz SA,Darabi M

更新日期：2012-08-15 00:00:00

abstract：BACKGROUND:Oesophagectomy remains the only curative intervention for oesophageal cancer, with defined nutritional and health-related quality of life (HR-QOL) consequences. It follows therefore that there is a significant risk of decline in physical wellbeing with oesophagectomy however this has been inadequately quanti...

journal_title：BMC cancer

authors： Guinan EM,Bennett AE,Doyle SL,O'Neill L,Gannon J,Foley G,Elliott JA,O'Sullivan J,Reynolds JV,Hussey J

更新日期：2019-07-12 00:00:00

abstract：BACKGROUND:Breast cancer places a heavy burden on the Australian healthcare system, but information about the actual number of women living with breast cancer and their current or future health service needs is limited. We used existing population-based data and innovative statistical methods to address this critical r...

journal_title：BMC cancer

authors： Yu XQ,De Angelis R,Luo Q,Kahn C,Houssami N,O'Connell DL

更新日期：2014-12-11 00:00:00

abstract：BACKGROUND:The aim of this study was to assess the feasibility and potential benefit of a brief psychosocial intervention based on cognitive-behavioral therapy performed in addition to early palliative care (PC) in the reduction of depressive symptoms among patients with advanced cancer. METHODS:An open-label randomiz...

journal_title：BMC cancer

authors： do Carmo TM,Paiva BSR,de Oliveira CZ,Nascimento MSA,Paiva CE

更新日期：2017-08-23 00:00:00

abstract：BACKGROUND:Ovarian cancer is associated with poor long-term survival due to late diagnosis and development of chemoresistance. Tumour hypoxia is associated with many features of tumour aggressiveness including increased cellular proliferation, inhibition of apoptosis, increased invasion and metastasis, and chemoresista...

journal_title：BMC cancer

authors： McEvoy LM,O'Toole SA,Spillane CD,Martin CM,Gallagher MF,Stordal B,Blackshields G,Sheils O,O'Leary JJ

更新日期：2015-07-25 00:00:00

abstract：BACKGROUND:Dabrafenib and trametinib combination therapy is approved for the treatment of patients with BRAF V600E positive tumors including melanoma and lung cancer. The effect of BRAF and MEK inhibitors on the immune system is not fully understood although a number of case reports indicate autoimmune side effects rel...

journal_title：BMC cancer

authors： Dimou A,Barron G,Merrick DT,Kolfenbach J,Doebele RC

更新日期：2020-03-04 00:00:00

abstract：BACKGROUND:The association of genes XRCC1, TP53 and MDM2 with breast cancer (BC) has never been tested in Kyrgyz population. We, therefore, aimed to identify an association of alleles and genotypes of polymorphic markers Arg399Gln of gene XRCC1, Arg72Pro of gene TP53, and T309G of gene MDM2 with the risk of BC in Kyrgy...

journal_title：BMC cancer

authors： Isakova J,Talaibekova E,Aldasheva N,Vinnikov D,Aldashev A

更新日期：2017-11-13 00:00:00

abstract：BACKGROUND:KIAA1199 is a recently identified novel gene that is up-regulated in human cancer with poor survival. Our proteomic study on signaling polarity in chemotactic cells revealed KIAA1199 as a novel protein target that may be involved in cellular chemotaxis and motility. In the present study, we examined the func...

journal_title：BMC cancer

authors： Jami MS,Hou J,Liu M,Varney ML,Hassan H,Dong J,Geng L,Wang J,Yu F,Huang X,Peng H,Fu K,Li Y,Singh RK,Ding SJ

更新日期：2014-03-15 00:00:00

abstract：BACKGROUND:Intrahepatic cholangiocarcinomas are malignant tumors arising from the intrahepatic biliary tract. The pathogenesis of these tumors remains unknown. Although there is a marked global variation in prevalence, some recent studies have suggested an increase in mortality from intrahepatic cholangiocarcinoma in s...

journal_title：BMC cancer

authors： Patel T

更新日期：2002-05-03 00:00:00

abstract：BACKGROUND:An understanding of growth dynamics of tumors is important in understanding progression of cancer and designing appropriate treatment strategies. We perform a comparative study of the hyperbolastic growth models with the Weibull and Gompertz models, which are prevalently used in the field of tumor growth. M...

journal_title：BMC cancer

authors： Eby WM,Tabatabai MA,Bursac Z

更新日期：2010-09-23 00:00:00

abstract：BACKGROUND:Cervical dysplasia and tumorigenesis have been linked with numerous chromosomal aberrations. The goal of this study was to evaluate 35 genomic regions associated with cervical disease and to select those which were found to have the highest frequency of aberration for use as probes in fluorescent in-situ hyb...

journal_title：BMC cancer

authors： Policht FA,Song M,Sitailo S,O'Hare A,Ashfaq R,Muller CY,Morrison LE,King W,Sokolova IA

更新日期：2010-08-16 00:00:00