Influence of different electrode belt positions on electrical impedance tomography imaging of regional ventilation: a prospective observational study.

abstract：BACKGROUND:This study aimed to investigate the feasibility of optical coherence tomography angiography (OCT-A) for quantitative analysis of flow density to assess changes in retinal perfusion in an experimental model of haemorrhagic shock. METHODS:Haemorrhagic shock was induced in five healthy, anaesthetized sheep by ...

journal_title：Critical care (London, England)

authors： Alnawaiseh M,Ertmer C,Seidel L,Arnemann PH,Lahme L,Kampmeier TG,Rehberg SW,Heiduschka P,Eter N,Hessler M

更新日期：2018-05-29 00:00:00

abstract：BACKGROUND:Heterogeneity of acute respiratory distress syndrome (ARDS) could be reduced by identification of biomarker-based phenotypes. The set of ARDS biomarkers to prospectively define these phenotypes remains to be established. OBJECTIVE:To provide an overview of the biomarkers that were multivariately associated ...

journal_title：Critical care (London, England)

authors： van der Zee P,Rietdijk W,Somhorst P,Endeman H,Gommers D

更新日期：2020-05-24 00:00:00

abstract：:With imprecise definitions, inexact measurement tools, and flawed study execution, our clinical science often lags behind bedside experience and simply documents what appear to be the apparent faults or validity of ongoing practices. These impressions are later confirmed, modified, or overturned by the results of the ...

journal_title：Critical care (London, England)

authors： Marini JJ,De Backer D,Ince C,Singer M,Van Haren F,Westphal M,Wischmeyer P

更新日期：2017-12-28 00:00:00

abstract：:Antithrombotic prophylaxis in critically ill patients frequently fails. Venous thromboembolism is associated with adverse clinical outcomes, including a prolonged intensive care unit stay and death. A potential mechanism by which critically ill patients may be predisposed to antithrombotic failure is the inability to ...

journal_title：Critical care (London, England)

authors： Crowther M,Lim W

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:A paucity of literature exists regarding delays in transfer out of the intensive care unit. We sought to analyze the incidence, causes, and costs of delayed transfer from a surgical intensive care unit (SICU). METHODS:An IRB-approved prospective observational study was conducted from January 24, 2010, to ...

journal_title：Critical care (London, England)

authors： Johnson DW,Schmidt UH,Bittner EA,Christensen B,Levi R,Pino RM

更新日期：2013-07-04 00:00:00

abstract：INTRODUCTION:The aim of the present study was to investigate the relationship between the blood IL-6 level, the blood glucose level, and glucose control in septic patients. METHODS:This retrospective observational study in a general ICU of a university hospital included a total of 153 patients with sepsis, severe seps...

journal_title：Critical care (London, England)

authors： Nakamura M,Oda S,Sadahiro T,Watanabe E,Abe R,Nakada TA,Morita Y,Hirasawa H

更新日期：2012-12-12 00:00:00

abstract：BACKGROUND:Sepsis is an important cause of neonatal morbidity and mortality; therefore, the early diagnosis of neonatal sepsis is essential. METHOD:Our aim was to compare the diagnostic accuracy of procalcitonin (PCT), C-reactive protein (CRP), procalcitonin combined with C-reactive protein (PCT + CRP) and presepsin i...

journal_title：Critical care (London, England)

authors： Ruan L,Chen GY,Liu Z,Zhao Y,Xu GY,Li SF,Li CN,Chen LS,Tao Z

更新日期：2018-11-21 00:00:00

abstract：:In the previous issue of Critical Care, Meybohm and colleagues provide evidence to support hypothermia as a kind of therapeutic option for patients suffering cardiac arrest. Although anesthetics had been used to induce hypothermia, sevoflurane post-conditioning fails to confer additional anti-inflammatory effects afte...

journal_title：Critical care (London, England)

authors： Zhang H

更新日期：2010-01-01 00:00:00

abstract：:The decision to transfuse a hospitalized patient must balance the known risks of transfusion with the need to provide adequate tissue oxygenation and the appropriate utilization of blood as a scarce resource. The minimum tolerated hemoglobin level is not well established, and considerable variation exists in intensivi...

journal_title：Critical care (London, England)

authors： Marshall JC

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Biomarkers can be of help to understand critical illness and to identify and stratify sepsis. Adrenomedullin is a vasoactive hormone, with reported prognostic and potentially therapeutic value in sepsis. The primary aim of this study was to investigate the association of circulating bioactive adrenomedullin ...

journal_title：Critical care (London, England)

authors： Lundberg OHM,Lengquist M,Spångfors M,Annborn M,Bergmann D,Schulte J,Levin H,Melander O,Frigyesi A,Friberg H

更新日期：2020-11-04 00:00:00

abstract：INTRODUCTION:Glial fibrillary acidic protein (GFAP) may serve as a serum marker of traumatic brain injury (TBI) that can be used to monitor biochemical changes in patients and gauge the response to treatment. However, the temporal profile of serum GFAP in the acute period of brain injury and the associated utility for ...

journal_title：Critical care (London, England)

authors： Lei J,Gao G,Feng J,Jin Y,Wang C,Mao Q,Jiang J

更新日期：2015-10-12 00:00:00

abstract：INTRODUCTION:Recent evidence suggests a link between excess lipid peroxidation and specific organ failures in sepsis. No study has been performed in sepsis by multidrug-resistant (MDR) Gram-negative bacteria. METHODS:Lethal sepsis was induced in rats by the intraperitoneal injection of one MDR isolate of Pseudomonas a...

journal_title：Critical care (London, England)

authors： Toufekoula C,Papadakis V,Tsaganos T,Routsi C,Orfanos SE,Kotanidou A,Carrer DP,Raftogiannis M,Baziaka F,Giamarellos-Bourboulis EJ

更新日期：2013-01-16 00:00:00

abstract：INTRODUCTION:Hypoxemia and high fractions of inspired oxygen (FiO2) are concerns in critically ill patients. An automated FiO2 controller based on continuous oxygen saturation (SpO2) measurement was tested. Two different SpO2-FiO2 feedback open loops, designed to react differently based on the level of hypoxemia, were ...

journal_title：Critical care (London, England)

authors： Saihi K,Richard JC,Gonin X,Krüger T,Dojat M,Brochard L

更新日期：2014-02-19 00:00:00

abstract：:Facilitation of early spontaneous breathing activity is the most important measure to shorten weaning and avoid ventilator-induced lung injury and diaphragmatic injury in mechanically ventilated patients. However, the optimal degree of spontaneous muscle activity and ventilator support remains to be determined. Furthe...

journal_title：Critical care (London, England)

authors： Calzia E,Dembinski R

更新日期：2013-11-19 00:00:00

abstract：BACKGROUND:Candidemia is an opportunistic infection associated with high morbidity and mortality in patients hospitalized both inside and outside intensive care units (ICUs). Identification of patients at risk is crucial to ensure prompt antifungal therapy. We sought to assess risk factors for candidemia and death, bot...

journal_title：Critical care (London, England)

authors： Poissy J,Damonti L,Bignon A,Khanna N,Von Kietzell M,Boggian K,Neofytos D,Vuotto F,Coiteux V,Artru F,Zimmerli S,Pagani JL,Calandra T,Sendid B,Poulain D,van Delden C,Lamoth F,Marchetti O,Bochud PY,FUNGINOS.,Allfun F

更新日期：2020-03-18 00:00:00

abstract：INTRODUCTION:Despite recent modifications, the clinical definition of the acute respiratory distress syndrome (ARDS) remains non-specific, leading to under-diagnosis and under-treatment. This study was designed to test the hypothesis that a biomarker panel would be useful for biologic confirmation of the clinical diagn...

journal_title：Critical care (London, England)

authors： Ware LB,Koyama T,Zhao Z,Janz DR,Wickersham N,Bernard GR,May AK,Calfee CS,Matthay MA

更新日期：2013-10-24 00:00:00

abstract：INTRODUCTION:Currently, little is known about the immunological characteristics of patients with avian influenza A (H7N9) virus infection. METHODS:The numbers and percentages of peripheral blood immune cells were measured in 27 patients with laboratory-confirmed H7N9 virus infection and 30 healthy controls (HCs). The ...

journal_title：Critical care (London, England)

authors： Wu W,Shi Y,Gao H,Liang W,Sheng J,Li L

更新日期：2014-03-24 00:00:00

abstract：INTRODUCTION:Some types of antimicrobial-coated central venous catheters (A-CVC) have been shown to be cost effective in preventing catheter-related bloodstream infection (CR-BSI). However, not all types have been evaluated, and there are concerns over the quality and usefulness of these earlier studies. There is uncer...

journal_title：Critical care (London, England)

authors： Halton KA,Cook DA,Whitby M,Paterson DL,Graves N

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:As more patients are surviving intensive care, mental health concerns in survivors have become a research priority. Among these, post-traumatic stress disorder (PTSD) can have an important impact on the quality of life of critical care survivors. However, data on its burden are conflicting. Therefore, this s...

journal_title：Critical care (London, England)

authors： Righy C,Rosa RG,da Silva RTA,Kochhann R,Migliavaca CB,Robinson CC,Teche SP,Teixeira C,Bozza FA,Falavigna M

更新日期：2019-06-11 00:00:00

abstract：INTRODUCTION:The objective of the study was to describe the pharmacokinetics (PK) of fluconazole, anidulafungin, and caspofungin in critically ill patients and to compare with previously published data. We also sought to determine whether contemporary fluconazole doses achieved PK/pharmacodynamic (PD; PK/PD) targets in...

journal_title：Critical care (London, England)

authors： Sinnollareddy MG,Roberts JA,Lipman J,Akova M,Bassetti M,De Waele JJ,Kaukonen KM,Koulenti D,Martin C,Montravers P,Rello J,Rhodes A,Starr T,Wallis SC,Dimopoulos G,DALI Study authors.

更新日期：2015-02-04 00:00:00

abstract：INTRODUCTION:Acute respiratory distress syndrome (ARDS) has heterogeneous etiologies, rapid progressive change and a high mortality rate. To improve the outcome of ARDS, accurate diagnosis is essential to the application of effective early treatment. The present study investigated the clinical effects and safety of ope...

journal_title：Critical care (London, England)

authors： Kao KC,Tsai YH,Wu YK,Chen NH,Hsieh MJ,Huang SF,Huang CC

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Abdominal compartment syndrome has been described in patients with severe acute pancreatitis, but its clinical impact remains unclear. We therefore studied patient factors associated with the development of intra-abdominal hypertension (IAH), the incidence of organ failure associated with IAH, and the effe...

journal_title：Critical care (London, England)

authors： De Waele JJ,Hoste E,Blot SI,Decruyenaere J,Colardyn F

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVES:We sought to study the association between sedation status, medications (benzodiazepines, opioids, and antipsychotics), and clinical outcomes in a resource-limited setting. DESIGN:A longitudinal study of critically ill participants on mechanical ventilation. SETTING:Five intensive care units (ICUs) in four...

journal_title：Critical care (London, England)

authors： Aragón RE,Proaño A,Mongilardi N,de Ferrari A,Herrera P,Roldan R,Paz E,Jaymez AA,Chirinos E,Portugal J,Quispe R,Brower RG,Checkley W

更新日期：2019-04-17 00:00:00

abstract：INTRODUCTION:Little is known about mortality rates following general surgical procedures in the United Kingdom. Deaths are most common in the 'high-risk' surgical population consisting mainly of older patients, with coexisting medical disease, who undergo major surgery. Only limited data are presently available to desc...

journal_title：Critical care (London, England)

authors： Pearse RM,Harrison DA,James P,Watson D,Hinds C,Rhodes A,Grounds RM,Bennett ED

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Patients with infective endocarditis (IE) have an elevated risk of renal dysfunction because of extensive systemic inflammation and use of nephrotoxic antibiotics. In this randomized, placebo-controlled trial, we investigated whether perioperative sodium bicarbonate administration could attenuate postoperati...

journal_title：Critical care (London, England)

authors： Cho JS,Soh S,Shim JK,Kang S,Choi H,Kwak YL

更新日期：2017-01-05 00:00:00

abstract：INTRODUCTION:A major pathophysiologic mechanism in sepsis is impaired host immunity which results in failure to eradicate invading pathogens and increased susceptibility to secondary infections. Although many immunosuppressive mechanisms exist, increased expression of the inhibitory receptor programmed cell death 1 (PD...

journal_title：Critical care (London, England)

authors： Chang K,Svabek C,Vazquez-Guillamet C,Sato B,Rasche D,Wilson S,Robbins P,Ulbrandt N,Suzich J,Green J,Patera AC,Blair W,Krishnan S,Hotchkiss R

更新日期：2014-01-04 00:00:00

abstract：INTRODUCTION:The objective was to study the effects of a novel lung volume optimization procedure (LVOP) using high-frequency oscillatory ventilation (HFOV) upon gas exchange, the transpulmonary pressure (TPP), and hemodynamics in a porcine model of surfactant depletion. METHODS:With institutional review board approva...

journal_title：Critical care (London, England)

authors： Karmrodt J,David M,Yuan S,Markstaller K

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:In order to improve assessment and outcome prediction in patients suffering from traumatic brain injury (TBI), cerebral protein levels in serum have been suggested as biomarkers of injury. However, despite much investigation, biomarkers have yet to reach broad clinical utility in TBI. This study is a 9-year ...

journal_title：Critical care (London, England)

authors： Thelin EP,Jeppsson E,Frostell A,Svensson M,Mondello S,Bellander BM,Nelson DW

更新日期：2016-09-08 00:00:00

abstract：INTRODUCTION:The aim of this study was to determine whether using pharmacodynamic-based dosing of antimicrobials, such as extended/continuous infusions, in critically ill patients is associated with improved outcomes as compared with traditional dosing methods. METHODS:We searched Medline, HealthStar, EMBASE, Cochrane...

journal_title：Critical care (London, England)

authors： Chant C,Leung A,Friedrich JO

更新日期：2013-11-29 00:00:00

abstract：INTRODUCTION:In the past two decades, healthcare adopted industrial strategies for process measurement and control. In the industry model, care is taken to avoid minimal deviations from a standard. In healthcare there is scarce data to support that a similar strategy can lead to better outcomes. Briefly, when complianc...

journal_title：Critical care (London, England)

authors： Amaral AC,Kure L,Jeffs A

更新日期：2012-05-08 00:00:00