Abstract:
:In the previous issue of Critical Care, Meybohm and colleagues provide evidence to support hypothermia as a kind of therapeutic option for patients suffering cardiac arrest. Although anesthetics had been used to induce hypothermia, sevoflurane post-conditioning fails to confer additional anti-inflammatory effects after cardiac arrest. Further research in this area is warranted.
journal_name
Crit Carejournal_title
Critical care (London, England)authors
Zhang Hdoi
10.1186/cc8923subject
Has Abstractpub_date
2010-01-01 00:00:00pages
137issue
2eissn
1364-8535issn
1466-609Xpii
cc8923journal_volume
14pub_type
评论,杂志文章相关文献
CRITICAL CARE文献大全abstract:INTRODUCTION:Fever is frequently observed in critically ill patients. An independent association of fever with increased mortality has been observed in non-neurological critically ill patients with mixed febrile etiology. The association of fever and antipyretics with mortality, however, may be different between infect...
journal_title:Critical care (London, England)
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1186/cc11211
更新日期:2012-02-28 00:00:00
abstract:INTRODUCTION:To provide up-to-date information on the prognostic factors associated with 28-day mortality in a cohort of septic shock patients in intensive care units (ICUs). METHODS:Prospective, multicenter, observational cohort study in ICUs from 14 French general (non-academic) and university teaching hospitals. Al...
journal_title:Critical care (London, England)
pub_type: 杂志文章,多中心研究
doi:10.1186/cc12598
更新日期:2013-04-25 00:00:00
abstract:INTRODUCTION:The accurate assessment of intravascular volume status for the therapy of severe hypovolemia and shock is difficult and critical to critically ill patients. Non-invasive evaluation of fluid responsiveness by the rapid infusion of a very limited amount of volume is an important clinical goal. This study aim...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc13891
更新日期:2014-05-27 00:00:00
abstract::The decision to transfuse a hospitalized patient must balance the known risks of transfusion with the need to provide adequate tissue oxygenation and the appropriate utilization of blood as a scarce resource. The minimum tolerated hemoglobin level is not well established, and considerable variation exists in intensivi...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc2846
更新日期:2004-01-01 00:00:00
abstract::Diagnosis of sepsis is complicated by non-specific clinical definitions and delays in laboratory analysis using tests which may have very poor predictive values. The use of host biomarker signature sets, which when measured in combination have high predictive values, offers a paradigm shift forwards for rapid, near-pa...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc13137
更新日期:2013-12-04 00:00:00
abstract::Sepsis, despite recent therapeutic progress, still carries unacceptably high mortality rates. The adrenergic system, a key modulator of organ function and cardiovascular homeostasis, could be an interesting new therapeutic target for septic shock. Beta-adrenergic regulation of the immune function in sepsis is complex ...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc8026
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Acute kidney injury (AKI) affects a large proportion of the critically ill and is associated with worse patient outcomes. Early identification of AKI can lead to earlier initiation of supportive therapy and better management. In this study, we evaluate the impact of computerized AKI decision support tool int...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-020-03343-1
更新日期:2020-11-23 00:00:00
abstract:INTRODUCTION:The administration of dopexamine may constitute a therapeutical option to improve hepatosplanchnic perfusion in sepsis. In order to verify this hypothesis, we administered dopexamine in an experimental sepsis model in rats. METHODS:This prospective, randomized, controlled laboratory study was conducted in...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc5011
更新日期:2006-01-01 00:00:00
abstract::High mobility group box protein 1 (HMGB1) has been shown to participate in acute inflammatory reactions, including acute lung injury and sepsis. There is also evidence that circulating levels of HMGB1 are increased after severe trauma and are associated with clinically important outcome parameters, including mortality...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc8141
更新日期:2009-01-01 00:00:00
abstract::The European Clinical Trials Directive requires an informed consent from the patient or a proxy in drug trials. Although informed consent is a valuable tool to protect patients' rights in clinical trials, this requirement largely impedes research in critical care settings, and if pursued in this context, it does not p...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc10113
更新日期:2011-01-01 00:00:00
abstract:INTRODUCTION:The main objective was to determine risk factors for presence of multidrug resistant bacteria (MDR) in postoperative peritonitis (PP) and optimal empirical antibiotic therapy (EA) among options proposed by Infectious Disease Society of America and the Surgical Infection Society guidelines. METHODS:One hun...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc8877
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Functional status (FS) before intensive care unit (ICU) admission is associated with short-term and long-term outcomes among critically ill patients. However, measures of FS are generally not integrated into ICU-specific mortality prediction models. METHODS:This retrospective cohort study used prospectively...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-017-1688-z
更新日期:2017-05-15 00:00:00
abstract:INTRODUCTION:Mortality and disability following ischemic stroke (IS) remains unacceptably high with respect to the conventional therapies. This study tested the effect of erythropoietin (EPO) on long-term neurological outcome in patients after acute IS. This study aimed to evaluate the safety and efficacy of two consec...
journal_title:Critical care (London, England)
pub_type: 杂志文章,随机对照试验
doi:10.1186/s13054-015-0761-8
更新日期:2015-02-25 00:00:00
abstract:BACKGROUND:Sepsis is an important cause of neonatal morbidity and mortality; therefore, the early diagnosis of neonatal sepsis is essential. METHOD:Our aim was to compare the diagnostic accuracy of procalcitonin (PCT), C-reactive protein (CRP), procalcitonin combined with C-reactive protein (PCT + CRP) and presepsin i...
journal_title:Critical care (London, England)
pub_type: 杂志文章,meta分析
doi:10.1186/s13054-018-2236-1
更新日期:2018-11-21 00:00:00
abstract::Regional citrate anticoagulation (RCA) is now recommended over systemic heparin for continuous renal replacement therapy in patients without contraindications. Its use is likely to increase throughout the world. However, in the absence of citrate blood level monitoring, the diagnosis of citrate accumulation, the most ...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-017-1880-1
更新日期:2017-11-19 00:00:00
abstract::Many advances in medicine have been achieved through challenging established dogma with revolutionary thought and novel practices. Each and every specialty is reinvigorated by regular re-evaluation of processes and practices in the light of new evidence and fresh conceptualization. Challenge can galvanize fresh thinki...
journal_title:Critical care (London, England)
pub_type: 杂志文章,评审
doi:10.1186/cc10245
更新日期:2011-07-26 00:00:00
abstract:INTRODUCTION:The goal of personalised medicine in the intensive care unit (ICU) is to predict which diagnostic tests, monitoring interventions and treatments translate to improved outcomes given the variation between patients. Unfortunately, processes such as gene transcription and drug metabolism are dynamic in the cr...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc7140
更新日期:2008-01-01 00:00:00
abstract::Several prognostic markers have been identified for patients admitted with acute cardiogenic pulmonary edema. Most of the markers are based on clinical risk scores. Unlike hypercapnic respiratory failure, acidosis is not an adverse predictor in these patients. Hemodynamic variables that assess pathophysiological mecha...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章,评审
doi:10.1186/cc9325
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Although early use of broad-spectrum antimicrobials in critically ill patients may increase antimicrobial adequacy, uncontrolled use of these agents may select for more-resistant organisms. This study investigated the effects of early use of broad-spectrum antimicrobials in critically ill patients with hos...
journal_title:Critical care (London, England)
pub_type: 杂志文章,随机对照试验
doi:10.1186/cc11197
更新日期:2012-02-15 00:00:00
abstract:INTRODUCTION:Mechanical ventilation with even moderate-sized tidal volumes synergistically increases lung injury in sepsis and has been associated with proinflammatory low-molecular-weight hyaluronan production. High-molecular-weight hyaluronan (HMW HA), in contrast, has been found to be anti-inflammatory. We hypothesi...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc6982
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Acute kidney injury and hyperchloremia are commonly present in critically ill septic patients. Our study goal was to evaluate the association of hyperchloremia and acute kidney injury in severe sepsis and septic shock patients. METHODS:In this retrospective cohort study in a provincial tertiary care hospita...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/s13054-016-1499-7
更新日期:2016-10-06 00:00:00
abstract:INTRODUCTION:The aim of this study was to determine whether the degree of fluid responsiveness in critically ill septic patients is related to baseline mixed venous oxygen saturation (SvO2) levels. We also sought to define whether fluid responsiveness would be less likely in the presence of a high SvO2 (>70%). METHODS...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc10326
更新日期:2011-07-26 00:00:00
abstract:BACKGROUND:The shock index (SI), defined as heart rate (HR) divided by systolic blood pressure (SBP), is reported to be a more sensitive marker of shock than traditional vital signs alone. In previous literature, use of the reverse shock index (rSI), taken as SBP divided by HR, is recommended instead of SI for hospital...
journal_title:Critical care (London, England)
pub_type: 杂志文章,多中心研究
doi:10.1186/s13054-018-2014-0
更新日期:2018-04-11 00:00:00
abstract:INTRODUCTION:Sepsis is a serious medical condition that requires rapidly administered, appropriate antibiotic treatment. Conventional methods take three or more days for final pathogen identification and antimicrobial susceptibility testing. We organized a prospective observational multicenter study in three study site...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc9234
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Sedation is widely used in intensive care unit (ICU) patients to limit the risk of pulmonary barotrauma and to decrease oxygen needs. However, adverse effects of cc5128sedation have not been fully evaluated; in particular, effects of benzodiazepine and opiates on microcirculation have not been extensively ...
journal_title:Critical care (London, England)
pub_type: 临床试验,杂志文章
doi:10.1186/cc5128
更新日期:2006-01-01 00:00:00
abstract::The rapid response system concept is one of the first patient-centered and organizational-wide systems aimed at preventing deaths and serious adverse events. It has been strongly argued that we need a benchmark that reflects the care of a deteriorating patient across the organization using a 'score to door time'; that...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc10477
更新日期:2011-01-01 00:00:00
abstract::Refractory cardiac shock in the cardiac surgical intensive care unit confers significant morbidity and mortality. Extracorporeal membrane oxygenation (ECMO) has become a common intervention for refractory cardiogenic shock when other therapies have failed. However, it is difficult to predict who will benefit from this...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc13736
更新日期:2014-02-20 00:00:00
abstract::The aim of perioperative haemodilution is to reduce loss of red blood cells during elective surgery. The oncotic and molecular characteristics of the various plasma substitutes employed determine how effectively normovolaemia is maintained, and their non-oncotic effects include alterations in microvascular perfusion. ...
journal_title:Critical care (London, England)
pub_type: 评论,杂志文章
doi:10.1186/cc6892
更新日期:2008-01-01 00:00:00
abstract:INTRODUCTION:Impaired skeletal muscle function has important clinical outcome implications for survivors of critical illness. Previous studies employing volitional manual muscle testing for diagnosing intensive care unit-acquired weakness (ICU-AW) during the early stages of critical illness have only provided limited d...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc13052
更新日期:2013-10-10 00:00:00
abstract:INTRODUCTION:Inter-hospital transport of critically ill patients is increasing. When performed by specialized retrieval teams there are less adverse events compared to transport by ambulance. These transports are performed with technical equipment also used in an Intensive Care Unit (ICU). As a consequence technical pr...
journal_title:Critical care (London, England)
pub_type: 杂志文章
doi:10.1186/cc11191
更新日期:2012-02-12 00:00:00