Glial fibrillary acidic protein as a biomarker in severe traumatic brain injury patients: a prospective cohort study.

abstract：INTRODUCTION:Bacterial infection represents a serious risk in neonates and critically ill paediatric patients. Current clinical practice is characterized by frequent antibiotic treatment despite low incidence of true infection. However, some patients escape early diagnosis and progress to septic shock. Many new markers...

journal_title：Critical care (London, England)

authors： Horisberger T,Harbarth S,Nadal D,Baenziger O,Fischer JE

更新日期：2004-12-01 00:00:00

abstract：:BACKGROUND: That thrombocytopenia results in increased mortality or transfusion requirements has not been confirmed by previous studies. We performed a case-control study in which 36 patients who developed severe thrombocytopenia of less than 50x109 platelets/l were carefully matched for the severity of underlying dis...

journal_title：Critical care (London, England)

authors： Stephan F,Montblanc Jd,Cheffi A,Bonnet F

更新日期：1999-01-01 00:00:00

abstract：:The epidemiology of severe acute renal failure has dramatically changed in the past decade. Its leading cause is sepsis and the syndrome develops mostly in the intensive care unit as part of multiple organ dysfunction syndrome. After the significant improvements obtained from the mid 1970s to the mid 1990s, the past d...

journal_title：Critical care (London, England)

authors： Ronco C

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Critical illness following head injury is associated with a hypermetabolic state but there are insufficient epidemiological data describing acute nutrition delivery to this group of patients. Furthermore, there is little information describing relationships between nutrition and clinical outcomes in this pop...

journal_title：Critical care (London, England)

authors： Chapple LA,Chapman MJ,Lange K,Deane AM,Heyland DK

更新日期：2016-01-07 00:00:00

abstract：INTRODUCTION:The appropriate strategy for trauma-induced coagulopathy management is under debate. We report the treatment of major trauma using mainly coagulation factor concentrates. METHODS:This retrospective analysis included trauma patients who received >or= 5 units of red blood cell concentrate within 24 hours. C...

journal_title：Critical care (London, England)

authors： Schöchl H,Nienaber U,Hofer G,Voelckel W,Jambor C,Scharbert G,Kozek-Langenecker S,Solomon C

更新日期：2010-01-01 00:00:00

abstract：:Cardiogenic shock is a lethal condition. Physicians are searching for hemodynamic markers which could help risk-stratification of patients in this picture. Torgersen and coworkers present an hourly time integral of the cardiac power index and cardiac index drops to predict outcomes in the setting of cardiogenic shock....

journal_title：Critical care (London, England)

authors： Yilmaz MB,Mebazaa A

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Acute respiratory failure (ARF) remains a common hazardous complication in immunocompromised patients and is associated with increased mortality rates when endotracheal intubation is needed. We aimed to evaluate the effect of early noninvasive ventilation (NIV) compared with oxygen therapy alone in this pati...

journal_title：Critical care (London, England)

authors： Huang HB,Xu B,Liu GY,Lin JD,Du B

更新日期：2017-01-07 00:00:00

abstract：BACKGROUND:The lack of a patent source of infection after 24 hours of management of shock considered septic is a common and disturbing scenario. We aimed to determine the prevalence and the causes of shock with no diagnosis 24 hours after its onset, and to compare the outcomes of patients with early-confirmed septic sh...

journal_title：Critical care (London, England)

authors： Contou D,Roux D,Jochmans S,Coudroy R,Guérot E,Grimaldi D,Ricome S,Maury E,Plantefève G,Mayaux J,Mekontso Dessap A,Brun-Buisson C,de Prost N

更新日期：2016-11-06 00:00:00

abstract：:During the past 50 years, caring for the critically ill has become increasingly complex and the need for an intensivist has become more evident. Management by intensivists has become a quality indicator for many ICUs. Numerous small studies have demonstrated the beneficial effect of intensivists on outcomes in the cri...

journal_title：Critical care (London, England)

authors： Levy MM

更新日期：2013-10-14 00:00:00

abstract：BACKGROUND:Hyperbilirubinaemia is a common occurrence in patients who are admitted to intensive care units (ICUs) after major surgery, and it is associated with high mortality. We investigated the incidence of hyperbilirubinaemia after two major types of thoracic surgery: open-heart surgery and oesophagectomy. In order...

journal_title：Critical care (London, England)

authors： Hosotsubo KK,Nishimura M,Nishimura S

更新日期：2000-01-01 00:00:00

abstract：INTRODUCTION:Prophylactic steroid therapy to reduce the occurrence of postextubation laryngeal edema is controversial. Only a limited number of prospective trials involve adults in an intensive care unit. The purpose of this study was to ascertain whether administration of multiple doses of dexamethasone to critically ...

journal_title：Critical care (London, England)

authors： Lee CH,Peng MJ,Wu CL

更新日期：2007-01-01 00:00:00

abstract：:A crucial determinant for the success of intensive insulin therapy in critically ill patients is the frequent and accurate measurement of blood glucose values with immediate feedback of results. In general, therefore, this is achieved by point-of-care testing, raising the question of the best way of monitoring blood g...

journal_title：Critical care (London, England)

authors： Brunkhorst FM,Wahl HG

更新日期：2006-01-01 00:00:00

abstract：:A new randomised controlled trial suggested that plasma exchange hastened removal from the ventilator in mechanically ventilated children with Guillain-Barré syndrome compared with intravenous immunoglobulin. Two larger trials in adults showed the opposite result. ...

journal_title：Critical care (London, England)

authors： Hughes RA

更新日期：2011-07-28 00:00:00

abstract：INTRODUCTION:The main objective was to determine risk factors for presence of multidrug resistant bacteria (MDR) in postoperative peritonitis (PP) and optimal empirical antibiotic therapy (EA) among options proposed by Infectious Disease Society of America and the Surgical Infection Society guidelines. METHODS:One hun...

journal_title：Critical care (London, England)

authors： Augustin P,Kermarrec N,Muller-Serieys C,Lasocki S,Chosidow D,Marmuse JP,Valin N,Desmonts JM,Montravers P

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Post-resuscitation hemodynamic instability following out-of-hospital cardiac arrest (OHCA) may occur from myocardial dysfunction underlying cardiogenic shock and/or inflammation-mediated distributive shock. Distinguishing the predominant shock subtype with widely available clinical metrics may have prognosti...

journal_title：Critical care (London, England)

authors： Anderson RJ,Jinadasa SP,Hsu L,Ghafouri TB,Tyagi S,Joshua J,Mueller A,Talmor D,Sell RE,Beitler JR

更新日期：2018-06-15 00:00:00

abstract：INTRODUCTION:Making a differential diagnosis between bacterial meningitis and aseptic meningitis is a critical clinical problem. The utility of a cerebrospinal fluid (CSF) lactate assay for this purpose has been debated and is not yet routinely clinically performed. To adequately evaluate this assay, a systematic revie...

journal_title：Critical care (London, England)

authors： Huy NT,Thao NT,Diep DT,Kikuchi M,Zamora J,Hirayama K

更新日期：2010-01-01 00:00:00

abstract：:Large quantitaties of inflammatory mediators are released during the course of endotoxaemia. These mediators in turn can stimulate the sympathetic nervous system (SNS) to release catecholamines, which ultimately regulate inflammation-associated impairment in tissue perfusion, myocardial impairment and vasodilatation. ...

journal_title：Critical care (London, England)

authors： Beck GCh,Brinkkoetter P,Hanusch C,Schulte J,van Ackern K,van der Woude FJ,Yard BA

更新日期：2004-12-01 00:00:00

abstract：INTRODUCTION:This prospective study aimed to assess whether use of the subxiphoid acoustic window in transthoracic echocardiography (TTE) can be an accurate alternative in the absence of an apical view to assess hemodynamic parameters. METHODS:This prospective study took place in a teaching hospital medical ICU. Over ...

journal_title：Critical care (London, England)

authors： Maizel J,Salhi A,Tribouilloy C,Massy ZA,Choukroun G,Slama M

更新日期：2013-09-03 00:00:00

abstract：BACKGROUND:In hospitalised patients, anaemia increases the risk of developing acute kidney injury (AKI). Our aim was to determine whether anaemia also has an impact on the risk of progression from early AKI to more severe AKI in critically ill patients. METHODS:We retrospectively analysed the data of patients admitted...

journal_title：Critical care (London, England)

authors： Powell-Tuck J,Crichton S,Raimundo M,Camporota L,Wyncoll D,Ostermann M

更新日期：2016-03-08 00:00:00

abstract：:An influenza pandemic threatens to be the most lethal public health crisis to confront the world. Physicians will have critical roles in diagnosis, containment and treatment of influenza, and their commitment to treat despite increased personal risks is essential for a successful public health response. The obligation...

journal_title：Critical care (London, England)

authors： Anantham D,McHugh W,O'Neill S,Forrow L

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Fever is associated with a poor outcome in severely brain-injured patients, and its control is one of the therapies used in this condition. But, fever suppression may promote infection, and severely brain-injured patients are frequently exposed to infectious diseases, particularly ventilator-associated pne...

journal_title：Critical care (London, England)

authors： Launey Y,Nesseler N,Le Cousin A,Feuillet F,Garlantezec R,Mallédant Y,Seguin P

更新日期：2014-12-15 00:00:00

abstract：:Owing to an increasing focus on the rising cost of medical care in the United States, bending the cost curve has become the central tenet of healthcare reform. The exact definition of this phrase, however, remains elusive. In order to affect change in the cost and quality of healthcare, the importance of comparative e...

journal_title：Critical care (London, England)

authors： Ghaferi AA

更新日期：2010-01-01 00:00:00

abstract：:Care of the critically ill patient is becoming increasingly complex. Protocols, which standardize care of patients with similar diseases, represent a potential solution to managing multiple simultaneous problems in critically ill patients. In this article, we examine the advantages and disadvantages to care protocoliz...

journal_title：Critical care (London, England)

authors： Chang SY,Sevransky J,Martin GS

更新日期：2012-01-01 00:00:00

abstract：:Even more than in previous disasters, Katrina has proven itself to be a testing ground for a plethora of new technologies. Although not all of these technologies did immediately save lives, in this regard a number of them exhibited considerable potential for the future, and hence there is a need to include them in fut...

journal_title：Critical care (London, England)

authors： Leitl E

更新日期：2006-02-01 00:00:00

abstract：:In an effort to reduce the complications related to invasive ventilation, the use of noninvasive ventilation (NIV) has increased over the last years in patients with acute respiratory failure. However, failure rates for NIV remain high in specific patient categories. Several studies have identified factors that contri...

journal_title：Critical care (London, England)

authors： Oppersma E,Doorduin J,van der Heijden EH,van der Hoeven JG,Heunks LM

更新日期：2013-12-05 00:00:00

abstract：:The Surviving Sepsis Campaign guidelines for the management of severe sepsis and septic shock recommend that the initial hemodynamic resuscitation be done according to the protocol used by Rivers and colleagues in their well-known early goal-directed therapy (EGDT) study. However, it may well be that their patients we...

journal_title：Critical care (London, England)

authors： Perel A

更新日期：2008-01-01 00:00:00

abstract：:The early recognition and management of sepsis remain the greatest challenges in the field of critical care medicine. Endothelial injury is one of the hallmarks of sepsis, leading to capillary leak, microcirculatory dysfunction, organ failure, and eventual death in many critically ill patients. The angiogenic growth f...

journal_title：Critical care (London, England)

authors： Giuliano JS Jr,Wheeler DS

更新日期：2009-01-01 00:00:00

abstract：:Vasopressin (antidiuretic hormone) is emerging as a potentially major advance in the treatment of septic shock. Terlipressin (tricyl-lysine-vasopressin) is the synthetic, long-acting analogue of vasopressin, and has comparable pharmacodynamic but different pharmacokinetic properties. Vasopressin mediates vasoconstrict...

journal_title：Critical care (London, England)

authors： Delmas A,Leone M,Rousseau S,Albanèse J,Martin C

更新日期：2005-04-01 00:00:00

abstract：:Respiratory tract obstruction due to a blood clot may result in life threatening ventilatory impairment. Ball valve blood clot obstructions of the airways are rare. A ball valve blood clot acts as a one-way valve, allowing (near) normal air entry into the airways, but (completely) blocking expiration. In a near fatal ...

journal_title：Critical care (London, England)

authors： Dongelmans DA,Jonkers RE,Schultz MJ

更新日期：2004-10-01 00:00:00

abstract：INTRODUCTION:Abdominal distension is common in critical illness. There is a growing recognition that intra-abdominal hypertension (IAH) may complicate nonsurgical critical illness as well as after abdominal surgery. However, the pathophysiological basis of the injury to the intestinal mucosal barrier and its influence ...

journal_title：Critical care (London, England)

authors： Cheng J,Wei Z,Liu X,Li X,Yuan Z,Zheng J,Chen X,Xiao G,Li X

更新日期：2013-12-09 00:00:00