An accurate test for homogeneity of odds ratios based on Cochran's Q-statistic.

abstract：BACKGROUND:Social-environmental data obtained from the US Census is an important resource for understanding health disparities, but rarely is the full dataset utilized for analysis. A barrier to incorporating the full data is a lack of solid recommendations for variable selection, with researchers often hand-selecting ...

journal_title：BMC medical research methodology

authors： Handorf E,Yin Y,Slifker M,Lynch S

更新日期：2020-12-10 00:00:00

abstract：BACKGROUND:Cluster randomised trials with unequal sized clusters often have lower precision than with clusters of equal size. To allow for this, sample sizes are inflated by a modified version of the design effect for clustering. These inflation factors are valid under the assumption that randomisation is stratified by...

journal_title：BMC medical research methodology

authors： Martin JT,Hemming K,Girling A

更新日期：2019-06-14 00:00:00

abstract：BACKGROUND:Multiple imputation (MI) provides an effective approach to handle missing covariate data within prognostic modelling studies, as it can properly account for the missing data uncertainty. The multiply imputed datasets are each analysed using standard prognostic modelling techniques to obtain the estimates of ...

journal_title：BMC medical research methodology

authors： Marshall A,Altman DG,Holder RL,Royston P

更新日期：2009-07-28 00:00:00

abstract：BACKGROUND:Sero- prevalence studies often have a problem of missing data. Few studies report the proportion of missing data and even fewer describe the methods used to adjust the results for missing data. The objective of this review was to determine the analytical methods used for analysis in HIV surveys with missing ...

journal_title：BMC medical research methodology

authors： Mosha NR,Aluko OS,Todd J,Machekano R,Young T

更新日期：2020-03-14 00:00:00

abstract：BACKGROUND:Multistate models have become increasingly useful to study the evolution of a patient's state over time in intensive care units ICU (e.g. admission, infections, alive discharge or death in ICU). In addition, in critically-ill patients, data come from different ICUs, and because observations are clustered int...

journal_title：BMC medical research methodology

authors： Liquet B,Timsit JF,Rondeau V

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:The systematic collection of high-quality mortality data is a prerequisite in designing relevant drowning prevention programmes. This descriptive study aimed to assess the quality (i.e., level of specificity) of cause-of-death reporting using ICD-10 drowning codes across 69 countries. METHODS:World Health O...

journal_title：BMC medical research methodology

authors： Lu TH,Lunetta P,Walker S

更新日期：2010-04-08 00:00:00

abstract：BACKGROUND:Chronic Obstructive Pulmonary Disease (COPD) is currently the fifth leading cause of death in Australia, and there are marked differences in mortality trends between men and women. In this study, we have sought to model and forecast age related changes in COPD mortality over time for men and women separately...

journal_title：BMC medical research methodology

authors： Erbas B,Ullah S,Hyndman RJ,Scollo M,Abramson M

更新日期：2012-02-21 00:00:00

abstract：BACKGROUND:Posttraumatic growth is the positive change resulting from traumatic experiences and is typically assessed with retrospective measures like the Posttraumatic Growth Inventory (PTGI). The PTGI was designed to include reference to a specific traumatic event, making it difficult to implement, without change, in...

journal_title：BMC medical research methodology

authors： Kaur N,Porter B,LeardMann CA,Tobin LE,Lemus H,Luxton DD,Millennium Cohort Study Team.

更新日期：2017-04-20 00:00:00

abstract：BACKGROUND:In prognostic studies model instability and missing data can be troubling factors. Proposed methods for handling these situations are bootstrapping (B) and Multiple imputation (MI). The authors examined the influence of these methods on model composition. METHODS:Models were constructed using a cohort of 58...

journal_title：BMC medical research methodology

authors： Vergouw D,Heymans MW,Peat GM,Kuijpers T,Croft PR,de Vet HC,van der Horst HE,van der Windt DA

更新日期：2010-09-17 00:00:00

abstract：BACKGROUND:Centralisation of thrombolysis may offer substantial benefits. The aim of this study was to assess short term costs and effects of centralisation of thrombolysis and optimised care in a decentralised system. METHODS:Using simulation modelling, three scenarios to improve decentralised settings in the North o...

journal_title：BMC medical research methodology

authors： Lahr MM,van der Zee DJ,Luijckx GJ,Vroomen PC,Buskens E

更新日期：2017-01-10 00:00:00

abstract：BACKGROUND:We would expect information on adverse drug reactions in randomised clinical trials to be easily retrievable from specific searches of electronic databases. However, complete retrieval of such information may not be straightforward, for two reasons. First, not all clinical drug trials provide data on the fre...

journal_title：BMC medical research methodology

authors： Derry S,Loke YK,Aronson JK

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Clinical study reports (CSRs) have been increasingly utilised within academic research in recent years. European Medicines Agency (EMA) Policy 0070 'Phase 1,' which came into effect in January 2015, requires the publication of regulatory documents such as CSRs from central applications in an anonymised forma...

journal_title：BMC medical research methodology

authors： Ferran JM,Nevitt SJ

更新日期：2019-11-05 00:00:00

abstract：BACKGROUND:Models of hepatitis C virus (HCV) kinetics are increasingly used to estimate and to compare in vivo drug's antiviral effectiveness of new potent anti-HCV agents. Viral kinetic parameters can be estimated using non-linear mixed effect models (NLMEM). Here we aimed to evaluate the performance of this approach ...

journal_title：BMC medical research methodology

authors： Laouénan C,Guedj J,Mentré F

更新日期：2013-04-25 00:00:00

abstract：BACKGROUND:Joint models of longitudinal and time-to-event data are increasingly used to perform individual dynamic prediction of a risk of event. However the difficulty to perform inference in nonlinear models and to calculate the distribution of individual parameters has long limited this approach to linear mixed-effe...

journal_title：BMC medical research methodology

authors： Desmée S,Mentré F,Veyrat-Follet C,Sébastien B,Guedj J

更新日期：2017-07-17 00:00:00

abstract：BACKGROUND:Video stimulated recall (VSR) is a method of enhancing participants' accounts of the consultation using a video recording of the event to encourage and prompt recall in a post consultation interview. VSR is used in education and education research, and to a lesser extent in medical and nursing research. Litt...

journal_title：BMC medical research methodology

authors： Paskins Z,McHugh G,Hassell AB

更新日期：2014-08-30 00:00:00

abstract：BACKGROUND:The aim was to describe a strategy for recruitment of healthy volunteers (HV) to a randomized trial that assessed the efficacy of different telephone techniques to assist HV in performing cardiac massage for vital emergency. Participation in the randomized trial was not financially compensated, however HV we...

journal_title：BMC medical research methodology

authors： Luzurier Q,Damm C,Lion F,Daniel C,Pellerin L,Tavolacci MP

更新日期：2015-01-05 00:00:00

abstract：BACKGROUND:Various papers have addressed pros and cons of the stepped wedge cluster randomized trial design (SWD). However, some issues have not or only limitedly been addressed. Our aim was to provide a comprehensive overview of all merits and limitations of the SWD to assist researchers, reviewers and medical ethics ...

journal_title：BMC medical research methodology

authors： de Hoop E,van der Tweel I,van der Graaf R,Moons KG,van Delden JJ,Reitsma JB,Koffijberg H

更新日期：2015-10-30 00:00:00

abstract：BACKGROUND:There is increasing awareness that meta-analyses require a sufficiently large information size to detect or reject an anticipated intervention effect. The required information size in a meta-analysis may be calculated from an anticipated a priori intervention effect or from an intervention effect suggested b...

journal_title：BMC medical research methodology

authors： Wetterslev J,Thorlund K,Brok J,Gluud C

更新日期：2009-12-30 00:00:00

abstract：BACKGROUND:Data on lifetime exposures are often self-reported in epidemiologic studies, sometimes many years after the relevant age. Validity of self-reported data is usually inferred from their agreement with measured values, but few studies directly quantify the likely effects of reporting errors in body size and rep...

journal_title：BMC medical research methodology

authors： Cairns BJ,Liu B,Clennell S,Cooper R,Reeves GK,Beral V,Kuh D

更新日期：2011-01-17 00:00:00

abstract：BACKGROUND:Compliance is a critical issue for parental questionnaires in school based epidemiological surveys and high compliance is difficult to achieve. The objective of this study was to determine trends and factors associated with parental questionnaire compliance during respiratory health surveys of school childre...

journal_title：BMC medical research methodology

authors： Koshy G,Brabin BJ

更新日期：2012-04-20 00:00:00

abstract：BACKGROUND:Occupational stress and specifically job anxiety are crucial factors in determining health outcomes, job satisfaction as well as performance. In order to assess this phenomenon, the Job Anxiety Scale is one of the instruments available. It consists of 70 items that are clustered in 14 subscales and five dime...

journal_title：BMC medical research methodology

authors： Schmalbach B,Kalkbrenner A,Bassler M,Hinz A,Petrowski K

更新日期：2020-04-21 00:00:00

abstract：BACKGROUND:Glaucoma is a leading cause of avoidable blindness worldwide. Open angle glaucoma is the most common type of glaucoma. No randomised controlled trials have been conducted evaluating the effectiveness of glaucoma screening for reducing sight loss. It is unclear what the most appropriate intervention to be eva...

journal_title：BMC medical research methodology

authors： Glaucoma screening Platform Study group.,Burr JM,Campbell MK,Campbell SE,Francis JJ,Greene A,Hernández R,Hopkins D,McCann SK,Vale LD

更新日期：2011-04-21 00:00:00

abstract：BACKGROUND:The ethical, methodological, and technical aspects of pediatric research, often results in complications and delays in implementation. Our objective was to identify factors associated with the implementation duration of hospital-based pediatric studies. METHODS:All hospital-based pediatric studies sponsored...

journal_title：BMC medical research methodology

authors： Meier-Girard D,Tibi A,Abdoul H,Prot-Labarthe S,Brion F,Bourdon O,Alberti C

更新日期：2016-03-29 00:00:00

abstract：BACKGROUND:Greater transparency and, in particular, sharing of patient-level data for further scientific research is an increasingly important topic for the pharmaceutical industry and other organisations who sponsor and conduct clinical trials as well as generally in the interests of patients participating in studies....

journal_title：BMC medical research methodology

authors： Tucker K,Branson J,Dilleen M,Hollis S,Loughlin P,Nixon MJ,Williams Z

更新日期：2016-07-08 00:00:00

abstract：BACKGROUND:Patient-reported outcome (PRO) measures play a key role in the advancement of patient-centered care research. The accuracy of inferences, relevance of predictions, and the true nature of the associations made with PRO data depend on the validity of these measures. Errors inherent to self-report measures can ...

journal_title：BMC medical research methodology

authors： Dowling NM,Bolt DM,Deng S,Li C

更新日期：2016-05-26 00:00:00

abstract：BACKGROUND:The mechanisms and pathways to impacts from public health research in the UK have not been widely studied. Through the lens of one funder (NIHR), our aims are to map the diversity of public health research, in terms of funding mechanisms, disciplinary contributions, and public health impacts, identify exampl...

journal_title：BMC medical research methodology

authors： Boulding H,Kamenetzky A,Ghiga I,Ioppolo B,Herrera F,Parks S,Manville C,Guthrie S,Hinrichs-Krapels S

更新日期：2020-02-19 00:00:00

abstract：BACKGROUND:Studies in both paediatric and psychiatric settings often experience problems in recruitment. This can compromise the ability of the study to recruit to target, meaning studies are potentially underpowered. It can also result in a biased sample if a non-representative group are selectively recruited. Recruit...

journal_title：BMC medical research methodology

authors： Loades ME,Smith L,Higson-Sweeney N,Beasant L,Stallard P,Kessler D,Crawley E

更新日期：2019-04-27 00:00:00

abstract：BACKGROUND:The reporting of randomised controlled trial (RCT) abstracts is of vital importance. The primary objective of this study was to investigate the association between structure format and RCT abstracts' quality of methodology reporting, informed by the current requirement and usage of structure formats by leadi...

journal_title：BMC medical research methodology

authors： Hua F,Walsh T,Glenny AM,Worthington H

更新日期：2018-01-10 00:00:00

abstract：BACKGROUND:The Computer Adaptive Test version of the Community Reintegration of Injured Service Members measure (CRIS-CAT) consists of three scales measuring Extent of, Perceived Limitations in, and Satisfaction with community integration. The CRIS-CAT was developed using item response theory methods. The purposes of t...

journal_title：BMC medical research methodology

authors： Resnik L,Borgia M,Ni P,Pirraglia PA,Jette A

更新日期：2012-09-17 00:00:00

abstract：BACKGROUND:Disease registers aim to collect information about all instances of a disease or condition in a defined population of individuals. Traditionally methods of operating disease registers have required that notifications of cases be identified by unique identifiers such as social security number or national iden...

journal_title：BMC medical research methodology

authors： Churches T

更新日期：2003-01-06 00:00:00