A case of metastatic renal cell carcinoma and bile duct carcinoma treated with a combination of sunitinib and gemcitabine.

abstract：BACKGROUND:Whether PET scan maximum standard uptake value (SUVmax) could differentiate luminal A from luminal B and help predict the survival of metastatic breast cancer (MBC) patients with luminal subtype is still unknown and need to be investigated. METHODS:305 MBC patients with luminal subtypes were screened with P...

journal_title：BMC cancer

authors： Zhang J,Jia Z,Ragaz J,Zhang YJ,Zhou M,Zhang YP,Li G,Wang BY,Wang ZH,Hu XC

更新日期：2013-01-31 00:00:00

abstract：BACKGROUND:MicroRNA (miR)-200c has been widely reported to be involved in colon cancer progress. However, the mechanisms of miR-200c in regulating tumor metastasis and growth remain to be fully elucidated. This study aimed to investigate the mechanism of miR-200c targets fucosyltransferase 4 (FUT4) on the proliferation...

journal_title：BMC cancer

authors： Cong J,Gong J,Yang C,Xia Z,Zhang H

更新日期：2021-01-04 00:00:00

abstract：BACKGROUND:In the presence of both HIV infection and cervical intraepithelial neoplasia (CIN), the risk of cancer development despite treatment may be greater. We investigated clinical predictors of persistent cytological abnormalities in women who had had a large loop excision of the transformation zone (LLETZ). METH...

journal_title：BMC cancer

authors： Adam Y,van Gelderen CJ,de Bruyn G,McIntyre JA,Turton DA,Martinson NA

更新日期：2008-07-25 00:00:00

abstract：BACKGROUND:During the last part of the 1990s the chance of surviving breast cancer increased. Changes in survival functions reflect a mixture of effects. Both, the introduction of adjuvant treatments and early screening with mammography played a role in the decline in mortality. Evaluating the contribution of these int...

journal_title：BMC cancer

authors： Vilaprinyo E,Rué M,Marcos-Gragera R,Martínez-Alonso M

更新日期：2009-03-30 00:00:00

abstract：BACKGROUND:Neoadjuvant systemic therapy (NST) is increasingly used in the treatment of breast cancer, yet it is clear that there is significant geographical variation in its use in the UK. This study aimed to examine stated practice across UK breast units, in terms of indications for use, radiological monitoring, patho...

journal_title：BMC cancer

authors： Whitehead I,Irwin GW,Bannon F,Coles CE,Copson E,Cutress RI,Dave RV,Gardiner MD,Grayson M,Holcombe C,Irshad S,O'Brien C,O'Connell RL,Palmieri C,Shaaban AM,Sharma N,Singh JK,Potter S,McIntosh SA,NeST Study Research Co

更新日期：2021-01-22 00:00:00

abstract：BACKGROUND:The classification of Breast Imaging Reporting and Data System 4A (BI-RADS 4A) lesions is mostly based on the personal experience of doctors and lacks specific and clear classification standards. The development of artificial intelligence (AI) provides a new method for BI-RADS categorisation. We analysed the...

journal_title：BMC cancer

authors： Niu S,Huang J,Li J,Liu X,Wang D,Zhang R,Wang Y,Shen H,Qi M,Xiao Y,Guan M,Liu H,Li D,Liu F,Wang X,Xiong Y,Gao S,Wang X,Zhu J

更新日期：2020-10-02 00:00:00

abstract：BACKGROUND:This study investigated whether patients with acquired haemolytic anaemia (AHA) would have elevated cancer risk including that for non-haematological solid tumours. We further examined whether the cancer risk would be different between patients with autoimmune type AHA (AIHA) and patients of non-AIHA. METHO...

journal_title：BMC cancer

authors： Kok VC,Sung FC,Kao CH,Lin CC,Tseng CH

更新日期：2016-02-04 00:00:00

abstract：BACKGROUND:To evaluate radiomics analysis in neuro-oncologic studies according to a radiomics quality score (RQS) system to find room for improvement in clinical use. METHODS:Pubmed and Embase were searched up the terms radiomics or radiogenomics and gliomas or glioblastomas until February 2019. From 189 articles, 51 ...

journal_title：BMC cancer

authors： Park JE,Kim HS,Kim D,Park SY,Kim JY,Cho SJ,Kim JH

更新日期：2020-01-10 00:00:00

abstract：BACKGROUND:Obesity is associated with tumor aggressiveness and disease-specific mortality for more than 15 defined malignancies, including prostate cancer. Preclinical studies suggest that weight loss from caloric restriction and increased physical activity may suppress hormonal, energy-sensing, and inflammatory factor...

journal_title：BMC cancer

authors： Demark-Wahnefried W,Nix JW,Hunter GR,Rais-Bahrami S,Desmond RA,Chacko B,Morrow CD,Azrad M,Frugé AD,Tsuruta Y,Ptacek T,Tully SA,Segal R,Grizzle WE

更新日期：2016-02-05 00:00:00

abstract：BACKGROUND:The receptor tyrosine kinases (RTKs) play critical roles in the development of cancers. Clear cell renal cell carcinoma (ccRCC) accounts for 75% of the RCC. The previous studies on the RTKs in ccRCCs mainly focused on their gene expressions. The activation and function of the RTKs in ccRCC have not been full...

journal_title：BMC cancer

authors： Zhang Q,Liu JH,Liu JL,Qi CT,Yan L,Chen Y,Yu Q

更新日期：2019-11-05 00:00:00

abstract：BACKGROUND:The main aim of this study was to investigate pre- and post-diagnostic physical activity (PA) levels, as well as changes in pre- and post-diagnostic PA levels, and their association with all-cause and breast cancer-specific mortality in women with breast cancer. Our study will add to the knowledge on whether...

journal_title：BMC cancer

authors： Borch KB,Braaten T,Lund E,Weiderpass E

更新日期：2015-12-16 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) isoforms, particularly the diffusible VEGF-121, could play a major role in the response of recurrent glioblastoma (GB) to anti-angiogenetic treatment with bevacizumab. We hypothesized that circulating VEGF-121 may reduce the amount of bevacizumab available to target ...

journal_title：BMC cancer

authors： Martini M,de Pascalis I,D'Alessandris QG,Fiorentino V,Pierconti F,Marei HE,Ricci-Vitiani L,Pallini R,Larocca LM

更新日期：2018-05-10 00:00:00

abstract：BACKGROUND:Uterine leiomyosarcoma (ULMS) is an aggressive form of soft tissue tumors. The molecular heterogeneity and pathogenesis of ULMS are not well understood. METHODS:Expression profiling data were used to determine the possibility and optimal number of ULMS molecular subtypes. Next, clinicopathological character...

journal_title：BMC cancer

authors： An Y,Wang S,Li S,Zhang L,Wang D,Wang H,Zhu S,Zhu W,Li Y,Chen W,Ji S,Guo X

更新日期：2017-09-11 00:00:00

abstract：BACKGROUND:The development and evaluation of new therapeutic approaches for malignant mesothelioma has been sparse due, in part, to lack of suitable tumor models. METHODS:We established primary mesothelioma cultures from pleural and ascitic fluids of five patients with advanced mesothelioma. Electron microscopy and im...

journal_title：BMC cancer

authors： Kalra N,Zhang J,Thomas A,Xi L,Cheung M,Talarchek J,Burkett S,Tsokos MG,Chen Y,Raffeld M,Miettinen M,Pastan I,Testa JR,Hassan R

更新日期：2015-05-08 00:00:00

abstract：BACKGROUND:Primary angiosarcomas of the right atrium are extremely rare, often resulted in missed diagnosis or misdiagnosis with routine examination tools. These malignant cardiac tumors are highly aggressive with generally poor prognosis. Surgical excision is the mainstay of treatment as it is essentially not responsi...

journal_title：BMC cancer

authors： Yu Y,Wang Q,Sun J,Zhao J,Chen S,Li Y

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:Breast cancer is the most common cancer type in female. As microRNAs play vital role in breast cancer, this study aimed to explore the molecular mechanism and clinical value of miR-21 in breast cancer. METHODS:qRT-PCR was performed to detect miR-21 levels in plasma of 127 healthy controls, 82 benign breast ...

journal_title：BMC cancer

authors： Wang H,Tan Z,Hu H,Liu H,Wu T,Zheng C,Wang X,Luo Z,Wang J,Liu S,Lu Z,Tu J

更新日期：2019-07-27 00:00:00

abstract：BACKGROUND:We previously reported that IL-6 and transglutaminase 2 (TG2) were expressed in more aggressive basal-like breast cancer cells, and TG2 and IL-6 expression gave these cells stem-cell-like phenotypes, increased invasive ability, and increased metastatic potential. In the present study, the underlying mechanis...

journal_title：BMC cancer

authors： Oh K,Lee OY,Park Y,Seo MW,Lee DS

更新日期：2016-09-08 00:00:00

abstract：BACKGROUND:Mammographic breast density and parenchymal patterns are well-established risk factors for breast cancer. We aimed to report inter-observer agreement on three different subjective ways of assessing mammographic density and parenchymal pattern, and secondarily to examine what potential impact reproducibility ...

journal_title：BMC cancer

authors： Winkel RR,von Euler-Chelpin M,Nielsen M,Diao P,Nielsen MB,Uldall WY,Vejborg I

更新日期：2015-04-12 00:00:00

abstract：BACKGROUND:Recent reports indicate the existence of breast cancer cells expressing very high levels of the Arylhydrocarbon receptor (AhR), a ubiquitous intracellular receptor best known for mediating toxic action of dioxin and related pollutants. Positive correlation between the degree of AhR overexpression and states ...

journal_title：BMC cancer

authors： Wong PS,Li W,Vogel CF,Matsumura F

更新日期：2009-07-15 00:00:00

abstract：BACKGROUND:The purpose of the PROLUCA study is to investigate the efficacy of preoperative and early postoperative rehabilitation in a non-hospital setting in patients with operable lung cancer with special focus on exercise. METHODS:Using a 2 x 2 factorial design with continuous effect endpoint (Maximal Oxygen Uptake...

journal_title：BMC cancer

authors： Sommer MS,Trier K,Vibe-Petersen J,Missel M,Christensen M,Larsen KR,Langer SW,Hendriksen C,Clementsen P,Pedersen JH,Langberg H

更新日期：2014-06-04 00:00:00

abstract：BACKGROUND:Infection with human papillomavirus (HPV) is necessary for the development of cervical carcinoma. By contrast, the role of HPV in the pathogenesis of other malignancies, such as head and neck cancers, is less well characterised. This study aimed to address key information gaps by conducting a systematic revi...

journal_title：BMC cancer

authors： Abogunrin S,Di Tanna GL,Keeping S,Carroll S,Iheanacho I

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:Toll-like receptors (TLRs) have garnered an extraordinary amount of interest in cancer research due to their role in tumor progression. By activating the production of several biological factors, TLRs induce type I interferons and other cytokines, which drive an inflammatory response and activate the adaptiv...

journal_title：BMC cancer

authors： González-Reyes S,Marín L,González L,González LO,del Casar JM,Lamelas ML,González-Quintana JM,Vizoso FJ

更新日期：2010-12-03 00:00:00

abstract：BACKGROUND:To the best of our knowledge, no study has reported mediastinal shift accompanied with obstructive atelectasis due to bulky primary esophageal tumor components treated with adaptive radiotherapy and concurrent chemotherapy. CASE PRESENTATION:Here we report the case of a 65-year-old male patient diagnosed wi...

journal_title：BMC cancer

authors： Sakanaka K,Fujii K,Mizowaki T

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:Improving the coordination of cancer care is a priority area for service improvement. However, quality improvement initiatives are hindered by the lack of accurate and reliable measures of this aspect of cancer care. This study was conducted to develop a questionnaire to measures patients' experience of canc...

journal_title：BMC cancer

authors： Young JM,Walsh J,Butow PN,Solomon MJ,Shaw J

更新日期：2011-07-15 00:00:00

abstract：BACKGROUNDS:There have been conflicting reports about serum golgi protein 73 (GP73) as one of the most promising serum markers for the diagnosis of hepatocellular carcinoma (HCC). This study was to make a systematic review about the diagnostic accuracy of serum GP73 versus alpha-fetoprotein (AFP) for HCC. METHODS:Afte...

journal_title：BMC cancer

authors： Zhou Y,Yin X,Ying J,Zhang B

更新日期：2012-01-16 00:00:00

abstract：BACKGROUND:Muscle invasive bladder cancer (MIBC) is often lethal and non-MIBC (NMIBC) can recur and progress, yet prognostic markers are currently inadequate. SAM68, a member of RNA-binding proteins, has been reported to contribute to progression of other cancers. The aim of this study is to investigate the potential u...

journal_title：BMC cancer

authors： Zhang Z,Yu C,Li Y,Jiang L,Zhou F

更新日期：2015-05-06 00:00:00

abstract：BACKGROUND:SET domain containing protein 2 (SETD2) is a histone methyltransferase that is involved in transcriptional elongation. There is evidence that SETD2 interacts with p53 and selectively regulates its downstream genes. Therefore, it could be implicated in the process of carcinogenesis. Furthermore, this gene is ...

journal_title：BMC cancer

authors： Al Sarakbi W,Sasi W,Jiang WG,Roberts T,Newbold RF,Mokbel K

更新日期：2009-08-21 00:00:00

abstract：BACKGROUND:5-fluorouracil, leucovorin, irinotecan and oxaliplatin (FOLFIRINOX) is superior to gemcitabine in patients with metastatic pancreatic cancer who have a good performance status. We investigated this combination as neoadjuvant therapy for locally advanced pancreatic cancer (LAPC). METHODS:In this retrospectiv...

journal_title：BMC cancer

authors： Hosein PJ,Macintyre J,Kawamura C,Maldonado JC,Ernani V,Loaiza-Bonilla A,Narayanan G,Ribeiro A,Portelance L,Merchan JR,Levi JU,Rocha-Lima CM

更新日期：2012-05-29 00:00:00

abstract：BACKGROUND:The association between immune-related adverse events (irAEs) and survival outcomes in patients with advanced melanoma receiving therapy with immune checkpoint inhibitors (ICIs) has not been well established, particularly in Asian melanoma. METHODS:We retrospectively reviewed 49 melanoma patients undergoing...

journal_title：BMC cancer

authors： Wu CE,Yang CK,Peng MT,Huang PW,Chang CF,Yeh KY,Chen CB,Wang CL,Hsu CW,Chen IW,Lin CT,Ueng SH,Lin G,Lin YF,Cheng CY,Chang JW

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:To date, the clinical benefit of topical steroid use has only been demonstrated for radiation dermatitis induced by 50-60 Gy irradiation in breast cancer. However, these agents are also often used clinically for the control of radiation dermatitis induced by high-dose (>60Gy) irradiation with chemotherapy in...

journal_title：BMC cancer

authors： Zenda S,Yamaguchi T,Yokota T,Miyaji T,Mashiko T,Tanaka M,Yonemura M,Takeno M,Okano T,Kawasaki T,Nakamori Y,Ishii S,Shimada S,Kanamaru M,Uchitomi Y

更新日期：2018-09-06 00:00:00