Abstract:
:Endometriosis is a clinical entity characterized by the presence of normal endometrial mucosa abnormally implanted in locations other than the uterine cavity. Endometriosis can be either endopelvic or extrapelvic depending on the location of endometrial tissue implantation. Despite the rarity of extrapelvic endometriosis, several cases of endometriosis of the gastrointestinal tract, the urinary tract, the upper and lower respiratory system, the diaphragm, the pleura and the pericardium, as well as abdominal scars loci have been reported in the literature. There are several theories about the pathogenesis and the pathophysiology of endometriosis. Depending on the place of endometrial tissue implantation, endometriosis can be expressed with a wide variety of symptoms. The diagnosis of this entity is neither easy nor routine. Many diagnostic methods clinical and laboratory have been used, but none of them is the golden standard. The multipotent localization of endometriosis in combination with the wide range of its clinical expression should raise the clinical suspicion in every woman with periodic symptoms of extrapelvic organs. Finally, the therapeutic approach of this clinical entity is also correlated with the bulk of endometriosis and the locum that it is found. It varies from simple observation, to surgical treatment and treatment with medication as well as a combination of those. Virtual slides: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1968087883113362.
journal_name
Diagn Patholjournal_title
Diagnostic pathologyauthors
Machairiotis N,Stylianaki A,Dryllis G,Zarogoulidis P,Kouroutou P,Tsiamis N,Katsikogiannis N,Sarika E,Courcoutsakis N,Tsiouda T,Gschwendtner A,Zarogoulidis K,Sakkas L,Baliaka A,Machairiotis Cdoi
10.1186/1746-1596-8-194subject
Has Abstractpub_date
2013-12-02 00:00:00pages
194issn
1746-1596pii
1746-1596-8-194journal_volume
8pub_type
杂志文章,评审abstract::Concurrent hematologic malignancies are relatively rare. We encountered a case of concurrent acute myeloid leukemia (AML) and T lymphoblastic lymphoma. The bone marrow chromosome analysis showed the karyotype 46, XY, t(5;12)(q33;p13), which indicated presence of PDGFRB gene translocations. Therefore, this disease belo...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/1746-1596-7-19
更新日期:2012-02-22 00:00:00
abstract::Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by recurrent coma, ventricular tachycardias and the replacement of the myocardium with fatty and fibrous tissue. We described a 42-year-old female patient without clinical arrhythmias which was diagnosed as ARVC by magnetic resonance imaging (MRI)...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/1746-1596-7-67
更新日期:2012-06-12 00:00:00
abstract:BACKGROUND:Gliomas are aggressive tumors of the central nervous system that rely on production of growth factors for tumor progression. Interleukin 8 (IL-8) is up-regulated in gliomas to promote angiogenesis and proliferation. The aim of this study was to evaluate the association of the IL-8 -251 T/A and +781 C/T polym...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/s13000-015-0378-x
更新日期:2015-08-07 00:00:00
abstract:BACKGROUND:Prostate cancer patients with rectal involvement are rare, and the factors associated with the survival of these patients are yet to be elucidated. PATIENTS AND METHODS:We collected data on patients who were admitted to our hospital for prostate cancer in the last thirteen years and of those in studies in t...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/1746-1596-9-35
更新日期:2014-02-20 00:00:00
abstract::Cutaneous apocrine carcinoma (AC) is a rare adnexal neoplasm that histologically can mimic breast carcinoma metastatic to the skin or apocrine carcinoma arising in ectopic breast tissue. As extremely rare condition, neuroendocrine differentiation may be observed in AC although its etiology and pathogenesis is still un...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/s13000-015-0302-4
更新日期:2015-06-10 00:00:00
abstract:BACKGROUND:Chronic hepatitis B virus (HBV) infection is a known major etiological factor for hepatocellular carcinoma (HCC) development. Alpha-fetoprotein (AFP) is widely used to detect primary HCC, whereas its sensitivity and specificity are not satisfying. Recently, circulating microRNAs (miRNAs) have been reported t...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/s13000-015-0369-y
更新日期:2015-07-28 00:00:00
abstract:OBJECTIVES:Non-Hodgkin's lymphoma (NHL) primarily derived from the base of the tongue, is rare. Human papillomavirus (HPV) and Epstein-Barr virus (EBV) are important aetiological risk factors for tumours of the head and neck. This study describes the clinicopathological features of NHL in the tongue base and the status...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/s13000-020-00936-w
更新日期:2020-04-01 00:00:00
abstract::Central neurocytoma/extraventricular neurocytoma is a central nervous system (CNS) tumor composed of uniform round cells with neuronal differentiation. The typical lesions of central neurocytoma/extraventricular neurocytoma are at the interventricular foramen of the lateral ventricles (central neurocytoma) or brain pa...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/s13000-015-0406-x
更新日期:2015-09-17 00:00:00
abstract:INTRODUCTION:Necrobiosis lipoidica diabeticorum is a rare disease of unclear etiology, that occurs in about 1% of diabetic patients. CASE REPORT:We present case of granulomatosis disciformis chronica et progressiva Miescher with good response to systemic corticosteroids therapy.Patient 45 years old woman, with primary...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/1746-1596-4-28
更新日期:2009-08-28 00:00:00
abstract::Bronchoalveolar lavage (BAL) is a useful diagnostic tool in interstitial lung diseases (ILD). However, differential cell counts are often non specific and immunocytochemistry is time consuming. Staining of glycoproteins by periodic acid Schiff (PAS) reaction may help in discriminating different forms of ILD. In additi...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/1746-1596-4-13
更新日期:2009-04-23 00:00:00
abstract:BACKGROUND:The microRNAs present a class of non-coding RNAs which are usually implicated in tumor biology. Recent report has unraveled that a novel member of microRNA family called miR-1246. However, the functional role and molecular mechanisms of miR-1246 in non-small cell lung cancer (NSCLC) is still elusive. METHOD...
journal_title:Diagnostic pathology
pub_type: 杂志文章,收录出版
doi:10.1186/s13000-015-0366-1
更新日期:2015-07-25 00:00:00
abstract:BACKGROUND:Rapid ("warm") autopsies of patients with advanced metastatic cancer provide important insight into the natural history, pathobiology and histomorphology of disease in treatment-resistant tumors. Plasmacytoid urothelial carcinoma (PUC) is a rare variant of urothelial carcinoma characterized by neoplastic cel...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/s13000-019-0896-z
更新日期:2019-10-21 00:00:00
abstract::Primary liver tumors in children are rare with malignant hepatoblastoma being the most common neoplasm. In this report, we describe the diagnosis and clinical management of a large liver tumor in a 3-year-old child that displayed the features of both, conventional hepatoblastoma and malignant teratoma. Pathological as...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/1746-1596-4-37
更新日期:2009-11-12 00:00:00
abstract:BACKGROUND:The transcriptional co-activator, TAZ, is an important effector of the Hippo pathway and is critical for the development of human cancers. However, the expression and prognostic significance of TAZ in retinoblastoma is currently unclear. METHODS:TAZ expression was examined in 43 retinoblastoma samples by im...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/s13000-015-0415-9
更新日期:2015-10-13 00:00:00
abstract:BACKGROUND:Fluorescence in situ hybridization (FISH) is one of the most powerful genetic analysis tools for pathological diagnoses. FISH can detect various genetic abnormalities including gene translocation that was specifically found in translocation-related sarcomas (TRSs). Here, we report the use of FISH in expert r...
journal_title:Diagnostic pathology
pub_type: 杂志文章,多中心研究
doi:10.1186/s13000-016-0486-2
更新日期:2016-04-12 00:00:00
abstract:BACKGROUND:Rhabdoid colorectal tumor (RCT) is a rare, highly aggressive neoplasm recurrent in elderly patients, commonly at the caecum. The molecular mechanisms underlying RCT pathogenesis remain poorly elucidated. The differential diagnosis is with the malignant rhabdoid tumors of infancy characterized by genetic inac...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/1746-1596-8-31
更新日期:2013-02-20 00:00:00
abstract:BACKGROUND:Gastrointestinal stromal tumors (GISTs), a type of mesenchymal tumor in the gastrointestinal tract, are believed to be closely associated with PDGFRA and C-KIT mutations. Schwannoma in the stomach, which is an unusual location, is a rare disorder. The simultaneous occurrence of the two diseases is rarer than...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/s13000-019-0898-x
更新日期:2019-10-23 00:00:00
abstract:BACKGROUND:The histopathological subtype, nuclear grade and presence or absence of comedonecrosis are established as critical elements in the reporting of ductal carcinoma in situ (DCIS) of the breast. The aims of this study were to determine the frequencies of morphological subtypes of DCIS, nuclear grade and comedone...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/s13000-014-0227-3
更新日期:2014-12-03 00:00:00
abstract:BACKGROUND:Advancing knowledge in molecular pathogenesis of hepatocellular carcinoma (HCC) opens up new horizons in the diagnostic, prognostic and therapeutic perspectives. Assessing the expression of molecular targets prior to definitive treatment is gaining importance in clinical practice. In this study, we investiga...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/s13000-017-0649-9
更新日期:2017-08-01 00:00:00
abstract::Primary pleural angiosarcoma is a rare and clinically aggressive tumor. Patients usually present with chest pain, dyspnea, hemoptysis and/or cough. Radiologic studies reveal diffuse pleural thickening and pleural effusion with or without mass lesion. The clinical and radiological features both resemble those of mesoth...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/1746-1596-6-130
更新日期:2011-12-30 00:00:00
abstract:UNLABELLED:As rare condition, mucoepidermoid carcinoma may occur in liver although its etiology and pathogenesis is still unclear. We report here a case of intrahepatic mucoepidermoid carcinoma misdiagnosed as cholangiocarcinoma and squamous cell carcinoma by preoperative radiologic and intraoperative histological exam...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/1746-1596-9-24
更新日期:2014-01-29 00:00:00
abstract:BACKGROUND:The programmed death receptor 1 (PD-1) protein is a cell-surface receptor on certain lymphocytes that, with its ligand programmed death ligand 1 (PD-L1), helps to down-regulate immune responses. Many cancer types express PD-L1 and evade immune recognition via the PD-1/PD-L1 interaction. Precision therapies t...
journal_title:Diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1186/s13000-018-0689-9
更新日期:2018-02-09 00:00:00
abstract:BACKGROUND:Epithelioid schwannoma as a rare variant poses a challenge to all pathologists, as this uncommon entity is extremely difficult to conclusively diagnose by morphological analyses on a resected sample alone owing to its unique histopathological features. However, few papers have described the detailed clinicop...
journal_title:Diagnostic pathology
pub_type: 杂志文章,评审
doi:10.1186/s13000-017-0604-9
更新日期:2017-01-19 00:00:00
abstract:BACKGROUND:Although often associated with holoprosencephaly, little detail of the histopathology of cyclopia is available. Here, we describe the ocular findings in a case of trisomy 13 to better understand the histogenesis of the rosettes, or tubules, characteristic of the retinal dysplasia associated with this conditi...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/1746-1596-2-48
更新日期:2007-12-18 00:00:00
abstract:UNLABELLED:Atypical teratoid/rhabdoid tumors are rare and highly malignant central nervous system tumors. They have no specific radiological features and often present several histological components that make a problem in differential diagnosis with medulloblastoma and primitive neuroectodermal tumors. We present the ...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/s13000-015-0284-2
更新日期:2015-05-02 00:00:00
abstract:BACKGROUND:Preventive and therapeutic options for renal failure are still limited. Gene expression profile analysis is powerful in the identification of biological differences between end stage renal failure patients and healthy controls. Previous studies mainly used variance/regression analysis without considering var...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/1746-1596-9-137
更新日期:2014-07-05 00:00:00
abstract:BACKGROUND:Appendiceal parasites can cause symptoms of appendiceal pain, independent of microscopic evidence of acute inflammation. The diagnosis of a parasitic infestation is generally achieved only after the pathologic examination of the resected appendices. PATIENTS/METHODS:Pathology department records were reviewe...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/1746-1596-2-16
更新日期:2007-05-24 00:00:00
abstract::Meningioma, craniopharyngeoma and glioma are mainly intracranial lesions. Nevertheless, in rare cases these entities may occur solely as extracranial lesions that may present as intranasal/sinusoidal masses, with headaches and nasal obstruction. We present three cases of common intracranial tumors, with purely extracr...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/1746-1596-3-14
更新日期:2008-04-16 00:00:00
abstract:BACKGROUND:To distinguish between malignant and benign lesions of the thyroid gland histological demonstration is often required since the fine-needle aspiration biopsy method applied pre-operatively has some limitations. In an attempt to improve diagnostic accuracy, markers using immunocytochemistry and immunohistoche...
journal_title:Diagnostic pathology
pub_type: 杂志文章,meta分析,评审
doi:10.1186/1746-1596-7-97
更新日期:2012-08-13 00:00:00
abstract:BACKGROUND:GATA-binding protein 3 (GATA3) has been identified as a sensitive marker for breast carcinoma but its sensitivity in primary genital extramammary Paget diseases (EMPDs) has not been well studied. METHODS:Here we investigated immunohistochemical expression of GATA3 in 72 primary genital EMPDs (35 from female...
journal_title:Diagnostic pathology
pub_type: 杂志文章
doi:10.1186/s13000-017-0638-z
更新日期:2017-07-10 00:00:00