Systemic endotoxin activity correlates with clot formation: an observational study in patients with early systemic inflammation and sepsis.

abstract：:The European Society of Intensive Care Medicine Annual Congress offers the opportunity for basic scientists and clinicians to share recent findings. Apart from the large number of free communications, several sessions of the congress were dedicated to state-of-the-art tutorials given by established speakers. The areas...

journal_title：Critical care (London, England)

authors： Preiser JC

更新日期：2001-12-01 00:00:00

abstract：:An influenza pandemic threatens to be the most lethal public health crisis to confront the world. Physicians will have critical roles in diagnosis, containment and treatment of influenza, and their commitment to treat despite increased personal risks is essential for a successful public health response. The obligation...

journal_title：Critical care (London, England)

authors： Anantham D,McHugh W,O'Neill S,Forrow L

更新日期：2008-01-01 00:00:00

abstract：:Despite progress in the diagnosis, prevention and therapy for hospital-acquired infections, ventilator-associated pneumonia (VAP) continues to complicate the course of a significant proportion of patients receiving mechanical ventilation. Mortality rates among patients with VAP have been reported to be as high as 72%,...

journal_title：Critical care (London, England)

authors： Rello J

更新日期：2005-06-01 00:00:00

abstract：:Carbon dioxide is a waste product of aerobic cellular respiration in all aerobic life forms. PaCO2 represents the balance between the carbon dioxide produced and that eliminated. Hypocapnia remains a common - and generally underappreciated - component of many disease states, including early asthma, high-altitude pulmo...

journal_title：Critical care (London, England)

authors： Curley G,Laffey JG,Kavanagh BP

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Sepsis is a major health issue in preterm infants. Biomarkers are used to diagnose and monitor patients with sepsis, but C-reactive protein (CRP) is proven not predictive at onset of late onset neonatal sepsis (LONS) diagnosis. The aim of this study was to evaluate the association of interleukin-6(IL-6), pro...

journal_title：Critical care (London, England)

authors： Kurul Ş,Simons SHP,Ramakers CRB,De Rijke YB,Kornelisse RF,Reiss IKM,Taal HR

更新日期：2021-01-06 00:00:00

abstract：INTRODUCTION:Evidence suggests that dying patients' physical and emotional suffering is inadequately treated in intensive care units. Although there are recommendations regarding decisions to forgo life-sustaining therapy, deciding on withdrawal of life support is difficult, and it is also difficult to decide who shoul...

journal_title：Critical care (London, England)

authors： Fumis RR,Deheinzelin D

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Pre-existing atrial fibrillation (AF) may worsen prognosis in patients admitted to the intensive care unit (ICU). METHODS:In a cohort study (2005-2011) including all patients with first-time ICU admissions in Denmark (n=57,110), we compared patients with and without pre-existing AF and estimated absolute ...

journal_title：Critical care (London, England)

authors： Gamst J,Christiansen CF,Rasmussen BS,Rasmussen LH,Thomsen RW

更新日期：2015-08-19 00:00:00

abstract：BACKGROUND:Recurrent delivery of tidal mechanical energy (ME) inflicts ventilator-induced lung injury (VILI) when stress and strain exceed the limits of tissue tolerance. Mechanical power (MP) is the mathematical description of the ME delivered to the respiratory system over time. It is unknown how ME relates to underl...

journal_title：Critical care (London, England)

authors： Kneyber MCJ,Ilia S,Koopman AA,van Schelven P,van Dijk J,Burgerhof JGM,Markhorst DG,Blokpoel RGT

更新日期：2020-10-07 00:00:00

abstract：:Mechanotransduction holds the underlying mechanisms of ventilator-induced lung injury. Research on this subject, however, could be difficult for clinicians, especially when results are controversial. A recent study by Li and co-workers is used as an example, to explain how to critically read literatures related to bas...

journal_title：Critical care (London, England)

authors： Liu M

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Mechanically ventilated critically ill patients frequently develop ventilator-associated pneumonia (VAP), a life-threatening complication. Proposed preventive measures against VAP include, but are not restricted to, selective decontamination of the digestive tract (SDD), selective oropharyngeal decontamina...

journal_title：Critical care (London, England)

authors： Schultz MJ,Haas LE

更新日期：2011-01-01 00:00:00

abstract：:Chloride is the principal anion in the extracellular fluid and is the second main contributor to plasma tonicity. Its concentration is frequently abnormal in intensive care unit patients, often as a consequence of fluid therapy. Yet chloride has received less attention than any other ion in the critical care literatur...

journal_title：Critical care (London, England)

authors： Yunos NM,Bellomo R,Story D,Kellum J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to assess the incidence of organ failure in trauma patients treated in an intensive care unit (ICU), and to study the relationship between organ failure and long-term survival and functional status. METHODS:This is a cohort study of all adult ICU trauma patients admitted to a unive...

journal_title：Critical care (London, England)

authors： Ulvik A,Kvåle R,Wentzel-Larsen T,Flaatten H

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to assess the effect of low-dose corticosteroid therapy in reducing shock duration after severe burn. METHODS:A placebo-controlled, double-blind, randomized clinical trial (RCT) was performed on two parallel groups in the burn intensive care unit (ICU). Patients were randomized t...

journal_title：Critical care (London, England)

authors： Venet F,Plassais J,Textoris J,Cazalis MA,Pachot A,Bertin-Maghit M,Magnin C,Rimmelé T,Monneret G,Tissot S

更新日期：2015-01-26 00:00:00

abstract：BACKGROUND:Acute kidney injury and hyperchloremia are commonly present in critically ill septic patients. Our study goal was to evaluate the association of hyperchloremia and acute kidney injury in severe sepsis and septic shock patients. METHODS:In this retrospective cohort study in a provincial tertiary care hospita...

journal_title：Critical care (London, England)

authors： Suetrong B,Pisitsak C,Boyd JH,Russell JA,Walley KR

更新日期：2016-10-06 00:00:00

abstract：BACKGROUND:Calcium release-activated calcium (CRAC) channel inhibitors stabilize the pulmonary endothelium and block proinflammatory cytokine release, potentially mitigating respiratory complications observed in patients with COVID-19. This study aimed to investigate the safety and efficacy of Auxora, a novel, intraven...

journal_title：Critical care (London, England)

authors： Miller J,Bruen C,Schnaus M,Zhang J,Ali S,Lind A,Stoecker Z,Stauderman K,Hebbar S

更新日期：2020-08-14 00:00:00

abstract：BACKGROUND:Hypernatraemia is common in inpatients and is associated with substantial morbidity. Its differential diagnosis is challenging, and delayed treatment may have devastating consequences. The most important hormone for the regulation of water homeostasis is arginine vasopressin, and copeptin, the C-terminal por...

journal_title：Critical care (London, England)

authors： Nigro N,Winzeler B,Suter-Widmer I,Schuetz P,Arici B,Bally M,Refardt J,Betz M,Gashi G,Urwyler SA,Burget L,Blum CA,Bock A,Huber A,Müller B,Christ-Crain M

更新日期：2018-02-09 00:00:00

abstract：:Experiencing treatment on a modern intensive care unit (ICU) is a potentially traumatic event. People who experience traumatic events have an increased risk of depression, anxiety disorders and post-traumatic stress disorder (PTSD). Extended follow-up has confirmed that many patients suffer physical and psychological ...

journal_title：Critical care (London, England)

authors： Hatch R,McKechnie S,Griffiths J

更新日期：2011-01-01 00:00:00

abstract：:In the previous issue of Critical Care, Meybohm and colleagues provide evidence to support hypothermia as a kind of therapeutic option for patients suffering cardiac arrest. Although anesthetics had been used to induce hypothermia, sevoflurane post-conditioning fails to confer additional anti-inflammatory effects afte...

journal_title：Critical care (London, England)

authors： Zhang H

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:The present study assessed the opinion of general practitioners (GPs) concerning their relationships with intensivists. METHODS:An anonymous questionnaire was mailed to 7,239 GPs. GPs were asked about their professional activities, postgraduate intensive care unit (ICU) training, the rate of patient admit...

journal_title：Critical care (London, England)

authors： Etesse B,Jaber S,Mura T,Leone M,Constantin JM,Michelet P,Zoric L,Capdevila X,Malavielle F,Allaouchiche B,Orban JC,Fabbro-Peray P,Lefrant JY,AzuRéa Group.

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Neurocritical illness is a growing healthcare problem with profound socioeconomic effects. We assessed differences in healthcare costs and long-term outcome for different forms of neurocritical illnesses treated in the intensive care unit (ICU). METHODS:We used the prospective Finnish Intensive Care Consort...

journal_title：Critical care (London, England)

authors： Raj R,Bendel S,Reinikainen M,Hoppu S,Laitio R,Ala-Kokko T,Curtze S,Skrifvars MB

更新日期：2018-09-20 00:00:00

abstract：INTRODUCTION:In critically ill patients, delirium is a serious and frequent disorder that is associated with a prolonged intensive care and hospital stay and an increased morbidity and mortality. Without the use of a delirium screening instrument, delirium is often missed by ICU nurses and physicians. The effects of im...

journal_title：Critical care (London, England)

authors： van den Boogaard M,Pickkers P,van der Hoeven H,Roodbol G,van Achterberg T,Schoonhoven L

更新日期：2009-01-01 00:00:00

abstract：:Recent studies challenge the utility of central venous pressure monitoring as a surrogate for cardiac preload. Starting with Starling's original studies on the regulation of cardiac output, this review traces the history of the experiments that elucidated the role of central venous pressure in circulatory physiology. ...

journal_title：Critical care (London, England)

authors： Berlin DA,Bakker J

更新日期：2015-02-16 00:00:00

abstract：INTRODUCTION:Our aim in this study was to assess whether the new Glasgow Coma Scale, Age, and Systolic Blood Pressure (GAP) scoring system, which is a modification of the Mechanism, Glasgow Coma Scale, Age, and Arterial Pressure (MGAP) scoring system, better predicts in-hospital mortality and can be applied more easily...

journal_title：Critical care (London, England)

authors： Kondo Y,Abe T,Kohshi K,Tokuda Y,Cook EF,Kukita I

更新日期：2011-08-10 00:00:00

abstract：BACKGROUND:Extracorporeal membrane oxygenation (ECMO) is a life-saving therapy in acute respiratory distress syndrome (ARDS) patients but is associated with complications and costs. Here, we validate various scores supposed to predict mortality and develop an optimized categorical model. METHODS:In a derivation cohort...

journal_title：Critical care (London, England)

authors： Hilder M,Herbstreit F,Adamzik M,Beiderlinden M,Bürschen M,Peters J,Frey UH

更新日期：2017-12-12 00:00:00

abstract：BACKGROUND:Sepsis is an important cause of neonatal morbidity and mortality; therefore, the early diagnosis of neonatal sepsis is essential. METHOD:Our aim was to compare the diagnostic accuracy of procalcitonin (PCT), C-reactive protein (CRP), procalcitonin combined with C-reactive protein (PCT + CRP) and presepsin i...

journal_title：Critical care (London, England)

authors： Ruan L,Chen GY,Liu Z,Zhao Y,Xu GY,Li SF,Li CN,Chen LS,Tao Z

更新日期：2018-11-21 00:00:00

abstract：INTRODUCTION:Thrombomodulin, which is expressed solely on monocytes, along with tissue factor (TF), takes part in coagulation and inflammation. Circulating blood monocytes can be divided into 3 major subtypes on the basis of their receptor phenotype: classical (CD14brightCD16negative, CMs), inflammatory (CD14brightCD16...

journal_title：Critical care (London, England)

authors： Hwang SM,Kim JE,Han KS,Kim HK

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Despite quick implementation of reperfusion therapies, a few patients with high-risk, acute, massive, pulmonary embolism (PE) remain highly hemodynamically unstable. Others have absolute contraindication to receive reperfusion therapies. Venoarterial-extracorporeal membrane oxygenation (VA-ECMO) might lower ...

journal_title：Critical care (London, England)

authors： Corsi F,Lebreton G,Bréchot N,Hekimian G,Nieszkowska A,Trouillet JL,Luyt CE,Leprince P,Chastre J,Combes A,Schmidt M

更新日期：2017-03-28 00:00:00

abstract：:Tight glycemic control in the ICU has been shown to reduce mortality in some but not all prospective randomized control trials. Confounding the interpretation of these studies are differences in how the control was achieved and underlying incidence of hypoglycemia, which can be expected to be affected by the introduct...

journal_title：Critical care (London, England)

authors： Steil GM,Agus MS

更新日期：2014-06-27 00:00:00

abstract：INTRODUCTION:Among critically ill patients with acute kidney injury (AKI) needing continuous renal replacement therapy (CRRT), the effect of convective (via continuous venovenous hemofiltration [CVVH]) versus diffusive (via continuous venovenous hemodialysis [CVVHD]) solute clearance on clinical outcomes is unclear. Ou...

journal_title：Critical care (London, England)

authors： Wald R,Friedrich JO,Bagshaw SM,Burns KE,Garg AX,Hladunewich MA,House AA,Lapinsky S,Klein D,Pannu NI,Pope K,Richardson RM,Thorpe K,Adhikari NK

更新日期：2012-10-24 00:00:00

abstract：INTRODUCTION:Protocols for the delivery of analgesia, sedation and delirium care of the critically ill, mechanically ventilated patient have been shown to improve outcomes but are not uniformly used. The extent to which elements of analgesia, sedation and delirium guidelines are incorporated into order sets at hospital...

journal_title：Critical care (London, England)

authors： Dale CR,Hayden SJ,Treggiari MM,Curtis JR,Seymour CW,Yanez ND 3rd,Fan VS

更新日期：2012-06-18 00:00:00