A rare case of rosai-dorfman disease in an adult male associated with auto-immune hemolytic anemia.

abstract：:Kikuchi-Fujimoto Disease (KFD), also known as histiocytic necrotizing lymphadenitis [corrected], is a benign, self-limiting disease that manifests primarily as cervical lymphadenopathy but may include low-grade fever, headache, and fatigue. There is a higher incidence of KFD in women aged 20-35 years and in Asian popu...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Deaver D,Naghashpour M,Sokol L

更新日期：2014-01-01 00:00:00

abstract：:Therapy for hemophilia has evolved in the last 40 years from plasma-based concentrates to recombinant proteins and, more recently, to non-factor therapeutics. Along this same timeline, research in adeno-associated viral (AAV) based gene therapy vectors has provided the framework for early phase clinical trials initial...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Arruda VR,Doshi BS

更新日期：2020-09-01 00:00:00

abstract：:The introduction of newer cytotoxic monoclonal antibodies and chimeric antigen receptor modified T cells is opening a new age in the management of B-lineage adult acute lymphoblastic leukemia. This therapeutic change must be very positively acknowledged because of the limits of intensive chemotherapy programs and allo...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Maino E,Scattolin AM,Viero P,Sancetta R,Pascarella A,Vespignani M,Bassan R

更新日期：2015-01-01 00:00:00

abstract：:HIV-associated PBL is an AIDS-defining cancer, classified by WHO as a distinct entity of aggressive DLBCL. To date less than 250 cases have been published, of them 17 are pediatric. The pathogenesis of this rare disease is related to immunodeficiency, chronic immune stimulation and EBV. Clinically is a rapid growing d...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Bibas M,Castillo JJ

更新日期：2014-11-01 00:00:00

abstract：:Sitagliptin, a modern antidiabetic agent which is weight neutral and associated with low rate of hypoglycaemias, is being increasingly used in type 2 diabetes mellitus (DM). However, there is a paucity of data about its efficacy and safety in beta-thalassaemia major (β-TM). This retrospective case series of five patie...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Zonoozi S,Barnard M,Prescott E,Jones R,Shah FT,Tzoulis P

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:This study aimed to compare polymerase chain reaction (PCR) and IgM detection using enzyme linked immune-sorbent assay (ELISA) in diagnosis of congenital cytomegalovirus (CMV) infection. METHODS:This study was conducted from May 2009 to December 2010. Urine and blood samples were collected from 94 neonates ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Albanna EA,El-Latif RS,Sharaf HA,Gohar MK,Ibrahim BM

更新日期：2013-07-10 00:00:00

abstract：Background:Italy has been one of the first European countries hit by the COVID-19 pandemic, with many patients dying from severe respiratory issues, especially frail subjects. Hematology patients are generally thought to be at high risk of developing severe COVID-19-associated complications. The aim of this work was to...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Botti S,Serra N,Castagnetti F,Chiaretti S,Mordini N,Gargiulo G,Orlando L

更新日期：2021-01-01 00:00:00

abstract：:The primary objective of this review was to update and discuss the current concepts and the results of the treatment of acute lymphoblastic leukemia (ALL) in adolescents and young adults (AYA). After a brief consideration of the epidemiologic and clinicobiologic characteristics of ALL in the AYA population, the main r...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Ribera JM,Ribera J,Genescà E

更新日期：2014-07-02 00:00:00

abstract：INTRODUCTION:Follicular lymphoma (FL) is an indolent lymphoproliferative disorder of B-cells with variable clinical behavior. It is the second most common subtype of Non-Hodgkin lymphoma in western countries but reported to have a lower incidence in Asia. MATERIALS AND METHODS:Cases of FL diagnosed in the Department o...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Sylvia MT,Dey B,Basu D,Jacob SE,Kar R,Dubashi B

更新日期：2016-11-01 00:00:00

abstract：:Allogeneic hematopoietic cell transplantation (HCT) is the only curative treatment for patients with myelodysplastic syndromes (MDS). Most patients with MDS are older than 60 years and age-associated morbidities limit the patients' options for curative transplant therapy. Since the development of conditioning regimens...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Field T,Anasetti C

更新日期：2010-08-05 00:00:00

abstract：:POEMS syndrome is a rare, chronic and disabling condition. The causes of this condition remain unknown; however, chronic overproduction of proinflammatory cytokines appears to be a major contributor. Early diagnosis is essential to start treatment before the clinical state of the patient becomes compromised. A complet...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Nozza A

更新日期：2017-09-01 00:00:00

abstract：:The clinical presentation of β-thalassemia intermedia phenotypes are influenced by many factors. The persistence of fetal hemoglobin and several polymorphisms located in the promoters of γ- and β-globin genes are some of them. The aim of this study was to evaluate the combined effect of the -158 Gγ (C→T) polymorphism ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Dabke P,Colah R,Ghosh K,Nadkarni A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Multiple myeloma (MM) is a haematological malignancy associated with kidney injury resulting from cast nephropathy, which can be caused by monoclonal free light chains (FLC). It has been demonstrated that early reduction of FLC can lead to a higher proportion of patients recovering renal function with a bett...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Khalafallah AA,Loi SW,Love S,Mohamed M,Mace R,Khalil R,Girgs M,Raj R,Mathew M

更新日期：2013-01-01 00:00:00

abstract：:Echinococcosis is an endemic zoonosis in the Mediterranean area, with Albania interested actually to a level that is becoming a public health concern. Authors describe preliminary data from the only tertiary (university) medical facility of Albania, positioned in the capital of the country (Tirana), with 333 new cases...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Pilaca A,Vyshka G,Pepa A,Shytaj K,Shtjefni V,Boçari A,Beqiri A,Kraja D

更新日期：2014-02-16 00:00:00

abstract：:This retrospective study was conducted to analyze clinical and laboratoristic parameters to individuate specific differences and facilitate differential diagnosis between Measles and Kawasaki Disease (KD) at first evaluation in an emergency room. We found similar clinical features as duration of fever and number of KD...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Buonsenso D,Macchiarulo G,Supino MC,La Penna F,Scateni S,Marchesi A,Reale A,Boccuzzi E

更新日期：2018-05-01 00:00:00

abstract：:The term splanchnic vein thrombosis encompasses Budd-Chiari syndrome (BCS), extrahepatic portal vein obstruction (EHPVO), and mesenteric vein thrombosis.Risk factors can be local or systemic. A local precipitating factor is rare in BCS, while it is common in patients with portal vein thrombosis. Chronic myeloprolifera...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： De Stefano V,Za T,Ciminello A,Betti S,Rossi E

更新日期：2011-01-01 00:00:00

abstract：:The inherited disorders of hemoglobin are by far the commonest monogenic diseases and there is considerable evidence that they have reached their very high frequencies due to heterozygote advantage against malaria. Recent studies have begun to clarify the effect of interactions between malaria and some of the more sev...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Weatherall DJ

更新日期：2009-12-20 00:00:00

abstract：INTRODUCTION:IGF-1 deficiency in TM patients in children and adolescents has been attributed to chronic anemia and hypoxia, chronic liver disease, iron overload and other associated endocrinopathies, e.g. growth hormone deficiency (GHD). Few data are available in the literature regarding adult TM patients and growth di...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： De Sanctis V,Soliman AT,Candini G,Yassin M,Raiola G,Galati MC,Elalaily R,Elsedfy H,Skordis N,Garofalo P,Anastasi S,Campisi S,Karimi M,Kattamis C,Canatan D,Kilinc Y,Sobti P,Fiscina B,El Kholy M

更新日期：2014-11-01 00:00:00

abstract：Introduction:The aim of the study was to enumerate the clinical, hematological, and molecular spectrum of G6PD deficiency in malaria endemic regions of south west Odisha. Methods:Diagnosis of G6PD deficiency was made by using the Di-chloroindophenol Dye test in two south west districts (Kalahandi and Rayagada) of Odis...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Kumar R,Singh MPSS,Mahapatra S,Chaurasia S,Tripathi MK,Oommen J,Bharti PK,Shanmugam R

更新日期：2020-03-01 00:00:00

abstract：:Life-threatening bleeding is a major and early complication of acute promyelocytic leukemia (APL), but in the last years there is a growing evidence of thromboses in APL. We report the first case of a young woman with dyspnea as the first symptom of APL due to massive pulmonary embolism (PE) successfully treated with ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Sorà F,Chiusolo P,Laurenti L,Autore F,Giammarco S,Sica S

更新日期：2016-07-01 00:00:00

abstract：Background:β-thalassemia intermedia (TI) spans a wide spectrum of severity and carries higher morbidity than previously recognized, including extramedullary hematopoiesis, leg ulcers, gallstones, thrombosis, secondary heart failure, pulmonary hypertension, skeletal deformity, growth retardation and endocrine abnormalit...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Yassin MA,Soliman AT,De Sanctis V,Yassin KS,Abdulla MA

更新日期：2019-05-01 00:00:00

abstract：:The transition of patients with ≥20% <30% bone marrow (BM) blast from the FAB category of myelodysplasia to the family of acute myeloid leukemia (AML) according to the recent WHO classification has not resolved the argument as to whether the natural history and responsiveness to therapy of these diseases is comparable...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Maurillo L,Buccisano F,Del Principe MI,Sarlo C,Di Caprio L,Ditto C,Giannotti F,Nasso D,Ceresoli E,Postorino M,Refrigeri M,Amadori S,Venditti A

更新日期：2013-06-03 00:00:00

abstract：BACKGROUND:Iron overload in patients with beta-thalassemia major (BTM) lead to alterations in the arterial structures and the thickness of the carotid arteries. Doppler ultrasound scanning of extra-cranial internal carotid arteries is non-invasive and relatively quick to perform and may identify children at increased r...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Abdelsamei HA,El-Sherif AM,Ismail AM,Abdel Hakeem GL

更新日期：2015-03-01 00:00:00

abstract：:Developing an effective malaria vaccine has been the goal of the scientific community for many years. A malaria vaccine, added to existing tools and strategies, would further prevent infection and decrease the unacceptable malaria morbidity and mortality burden. Great progress has been made over the last decade and a ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： García-Basteiro AL,Bassat Q,Alonso PL

更新日期：2012-01-01 00:00:00

abstract：:Tenofovir is widely used as first-line treatment of HIV infection, although its use is sometimes complicated by a reversible proximal renal tubulopathy.We report the case of a 45-year-old woman with chronic HIV infection and personality disorder, who after 12 months of tenofovir, complained of fatigue, diffuse bone pa...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： De Socio GV,Fabbriciani G,Massarotti M,Messina S,Cecchini E,Marasini B

更新日期：2012-01-01 00:00:00

abstract：:Acinetobacter baumannii is an important opportunistic pathogen, responsible for approximately 10% of all gram-negative nosocomial infection. The aim of this study was to determine aminoglycoside and quinolone resistance genes and their antimicrobial susceptibility profile in the clinically A. baumannii. In this cross-...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Mirnejad R,Heidary M,Bahramian A,Goudarzi M,Pournajaf A

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Beta thalassemia is an inherited hemoglobin disorder resulting in a severe, chronic anemia requiring life-long blood transfusion that induces iron overload. Silymarin is a flavonoid complex isolated from Silybin marianum with a strong antioxidant activity, inducing an hepatoprotective action, and probably, a...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Hagag AA,Elfrargy MS,Gazar RA,El-Lateef AE

更新日期：2013-11-04 00:00:00

abstract：:A 71 year old female with multiple myeloma presented with back pain seven year after autologous stem cell transplant. Skeletal bone survey and magnetic resonance imaging did not show a relapse that was evidenced by CT/PET. Lenalidomide as single agent induced a complete disappearance of the lesions 6 months later and ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Gozzetti A,Rossi V,Cerase A,Papini G,Defina M,Bocchia M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Cardiac iron toxicity is the leading cause of death among β-halassaemia major (TM) patients. Once heart failure becomes overt, it is difficult to reverse. OBJECTIVES:To investigate non-overt cardiac dysfunctions in TM patients using pulsed wave Tissue Doppler Imaging (TD I) and its relation to iron overload...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Ragab SM,Fathy WM,El-Aziz WF,Helal RT

更新日期：2015-08-24 00:00:00

abstract：Background:Although bronchoalveolar lavage (BAL) measurements of galactomannan antigen (GM) seems to be more sensitive than serum testing to detect invasive fungal infection (IFI), a consensus on the most appropriate diagnostic threshold of the BAL GM test is still unclear. Moreover, there is uncertainty as to whether ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Cefalo M,Puxeddu E,Sarmati L,Paterno G,Fontana C,Nasso D,Pane G,De Bellis E,Palmieri R,Buzzati E,Meconi F,Laureana R,Casciani P,Zizzari AG,Rogliani P,de Fabritiis P,Maurillo L,Buccisano F,Cantonetti M,Arcese W,Ven

更新日期：2019-11-01 00:00:00