Current knowledge on HIV-associated Plasmablastic Lymphoma.

abstract：OBJECTIVES:Low-dose cytarabine (LD-AraC) is still regarded as the standard of care in elderly patients with acute myeloid leukemia (AML) 'unfit' for intensive chemotherapy. In this study, we reported our experience with LD-AraC in patients ≥ 70 years old and compared the results to those of intensive chemotherapy, best...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Heiblig M,Elhamri M,Tigaud I,Plesa A,Barraco F,Labussière H,Ducastelle S,Michallet M,Nicolini F,Plesa C,Wattel E,Salles G,Thomas X

更新日期：2016-01-01 00:00:00

abstract：:This retrospective study was conducted to analyze clinical and laboratoristic parameters to individuate specific differences and facilitate differential diagnosis between Measles and Kawasaki Disease (KD) at first evaluation in an emergency room. We found similar clinical features as duration of fever and number of KD...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Buonsenso D,Macchiarulo G,Supino MC,La Penna F,Scateni S,Marchesi A,Reale A,Boccuzzi E

更新日期：2018-05-01 00:00:00

abstract：Background:β-thalassemia intermedia (TI) spans a wide spectrum of severity and carries higher morbidity than previously recognized, including extramedullary hematopoiesis, leg ulcers, gallstones, thrombosis, secondary heart failure, pulmonary hypertension, skeletal deformity, growth retardation and endocrine abnormalit...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Yassin MA,Soliman AT,De Sanctis V,Yassin KS,Abdulla MA

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Iron overload in patients with beta-thalassemia major (BTM) lead to alterations in the arterial structures and the thickness of the carotid arteries. Doppler ultrasound scanning of extra-cranial internal carotid arteries is non-invasive and relatively quick to perform and may identify children at increased r...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Abdelsamei HA,El-Sherif AM,Ismail AM,Abdel Hakeem GL

更新日期：2015-03-01 00:00:00

abstract：:In Primary Myelofibrosis (PMF), megakaryocyte dysplasia/hyperplasia determines the release of inflammatory cytokines that, in turn, stimulate stromal cells and induce bone marrow fibrosis. The pathogenic mechanism and the cells responsible for progression to bone marrow fibrosis in PMF are not completely understood. T...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Malara A,Abbonante V,Zingariello M,Migliaccio A,Balduini A

更新日期：2018-11-01 00:00:00

abstract：:The inherited disorders of hemoglobin are by far the commonest monogenic diseases and there is considerable evidence that they have reached their very high frequencies due to heterozygote advantage against malaria. Recent studies have begun to clarify the effect of interactions between malaria and some of the more sev...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Weatherall DJ

更新日期：2009-12-20 00:00:00

abstract：BACKGROUND:Better survival of thalassemia patients allowed previously unrecognized renal complications to emerge. OBJECTIVES:Assess prevalence and early predictors of renal dysfunction in young β-thalassemia major (β-TM) and intermedia (β-TI) patients. SUBJECTS:66 β-TM (group I), 26 β-TI (group II) Egyptian patients ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Tantawy AA,El Bablawy N,Adly AA,Ebeid FS

更新日期：2014-09-01 00:00:00

abstract：INTRODUCTION:IGF-1 deficiency in TM patients in children and adolescents has been attributed to chronic anemia and hypoxia, chronic liver disease, iron overload and other associated endocrinopathies, e.g. growth hormone deficiency (GHD). Few data are available in the literature regarding adult TM patients and growth di...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： De Sanctis V,Soliman AT,Candini G,Yassin M,Raiola G,Galati MC,Elalaily R,Elsedfy H,Skordis N,Garofalo P,Anastasi S,Campisi S,Karimi M,Kattamis C,Canatan D,Kilinc Y,Sobti P,Fiscina B,El Kholy M

更新日期：2014-11-01 00:00:00

abstract：:Hemophagocytic Lymphohistiocytosis (HLH) is an indicator of an exaggerated immune response and eventually adverse outcomes. This study aimed to investigate the clinical and laboratory features and outcomes of patients with HLH. The medical records of 26 HLH adult patients (≥ 16 years of age) were retrospectively analy...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Arslan F,Alp S,Büyükasık Y,Ozkan MC,Şahin F,Basaran S,Cagatay AA,Eraksoy ÖH,Aksu K,Ertunç B,Korten V,Ceylan B,Mert A

更新日期：2018-09-01 00:00:00

abstract：:Developing an effective malaria vaccine has been the goal of the scientific community for many years. A malaria vaccine, added to existing tools and strategies, would further prevent infection and decrease the unacceptable malaria morbidity and mortality burden. Great progress has been made over the last decade and a ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： García-Basteiro AL,Bassat Q,Alonso PL

更新日期：2012-01-01 00:00:00

abstract：:Life-threatening bleeding is a major and early complication of acute promyelocytic leukemia (APL), but in the last years there is a growing evidence of thromboses in APL. We report the first case of a young woman with dyspnea as the first symptom of APL due to massive pulmonary embolism (PE) successfully treated with ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Sorà F,Chiusolo P,Laurenti L,Autore F,Giammarco S,Sica S

更新日期：2016-07-01 00:00:00

abstract：:POEMS syndrome is a rare, chronic and disabling condition. The causes of this condition remain unknown; however, chronic overproduction of proinflammatory cytokines appears to be a major contributor. Early diagnosis is essential to start treatment before the clinical state of the patient becomes compromised. A complet...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Nozza A

更新日期：2017-09-01 00:00:00

abstract：:Allogeneic hematopoietic cell transplantation (HCT) is the only curative treatment for patients with myelodysplastic syndromes (MDS). Most patients with MDS are older than 60 years and age-associated morbidities limit the patients' options for curative transplant therapy. Since the development of conditioning regimens...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Field T,Anasetti C

更新日期：2010-08-05 00:00:00

abstract：INTRODUCTION:Bortezomib is a proteasome inhibitor that targets myeloma cell and its bone marrow microenvironment. Intravenous Bortezomib with or without dexamethasone, is effective and well tolerated in patients with relapsed/refractory multiple myeloma (MM). METHODS:We used Bortezomib without corticosteroids, to avoi...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Gentilini F,Levi A,Federico V,Russo E,Foà R,Petrucci MT

更新日期：2012-01-01 00:00:00

abstract：:The clinical manifestations of severe malaria are several and occur in different anatomical sites. Both parasite- and host-related factors contribute to the pathogenicity of the severe forms of the disease. Cytoadherence of infected red blood cells to the vascular endothelium of different organs and rosetting are uniq...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Autino B,Corbett Y,Castelli F,Taramelli D

更新日期：2012-01-01 00:00:00

abstract：:The primary objective of this review was to update and discuss the current concepts and the results of the treatment of acute lymphoblastic leukemia (ALL) in adolescents and young adults (AYA). After a brief consideration of the epidemiologic and clinicobiologic characteristics of ALL in the AYA population, the main r...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Ribera JM,Ribera J,Genescà E

更新日期：2014-07-02 00:00:00

abstract：:JAK2V617F is a gain of function point mutation that occurs in Myeloproliferative Neoplasm (MPN) patients and deranges their hemopoiesis at cellular level. We speculate that hyperfunctioning JAK2 can modify osteoclast (OCL) homeostasis in MPN patients. We studied 18 newly diagnosed MPN patients and four age-matched nor...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Spanoudakis E,Papoutselis M,Bazdiara I,Lamprianidi E,Kordella X,Tilkeridis C,Tsatalas C,Kotsianidis I

更新日期：2018-11-01 00:00:00

abstract：:The B-cell receptor (BCR) signaling inhibitors ibrutinib and idelalisib are revolutionizing the treatment of chronic lymphocytic leukemia (CLL) and other B-cell malignancies. These oral agents, both alone and in combination with other drugs, have shown remarkable clinical activity in relapsed or refractory CLL across ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Falchi L,Baron JM,Orlikowski CA,Ferrajoli A

更新日期：2016-02-10 00:00:00

abstract：INTRODUCTION:Sickle cell disease (SCD) is one of the leading causes of morbidity and mortality worldwide, causing damage and dysfunction in multiple organs. The complications of this disease are numerous, affect every organ and/or tissue in the body and vary considerably among patients over the time challenging its man...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Yassin M,Soliman A,De Sanctis V,Nashwan A,Abusamaan S,Moustafa A,Kohla S,Soliman D

更新日期：2017-06-20 00:00:00

abstract：:The large multimeric glycoprotein Von Willebrand factor (VWF) is best known for its role in haemostasis; however in recent years other functions of VWF have been identified, indicating that this protein is involved in multiple vascular processes. We recently described a new role for VWF in controlling angiogenesis, wh...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Randi AM,Laffan MA,Starke RD

更新日期：2013-09-02 00:00:00

abstract：BACKGROUND:Homozygous or double heterozygous factor XIII (FXIII) deficiency is characterized by soft tissue hematomas, intracranial and delayed spontaneous bleeding. Alterations of thromboelastography (TEG) parameters in these patients have been reported. The aim of the study was to show results of TEG, TEG Lysis (Lys ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Martinuzzo M,Barrera L,Altuna D,Baña FT,Bieti J,Amigo Q,D'Adamo M,López MS,Oyhamburu J,Otaso JC

更新日期：2016-08-16 00:00:00

abstract：:Long-term survival of relapsed/refractory acute myeloid leukemia (AML) remains a major problem, particularly in patients not eligible for transplantation.We hereby evaluated the feasibility and efficacy of adding Gemtuzumab Ozogamicin to salvage chemotherapy (Ara-C, Idarubicine, Peg-Filgrastim) in relapsed/refractory ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Capria S,Trisolini SM,Minotti C,Stefanizzi C,Cardarelli L,Cartoni C,Diverio D,De Propris MS,Mancini M,Micozzi A,Foà R,Meloni G

更新日期：2012-01-01 00:00:00

abstract：:Human coronaviruses (HCoVs) commonly cause mild upper-respiratory tract illnesses but can lead to more severe and diffusive diseases. A variety of signs and symptoms may be present, and infections can range in severity from the common cold and sore throat to more serious laryngeal or tracheal infections, bronchitis, a...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Lassandro G,Palladino V,Amoruso A,Palmieri VV,Russo G,Giordano P

更新日期：2020-07-01 00:00:00

abstract：:Idiopathic thrombocytopenic purpura (ITP) is an autoimmune hematological disorder characterized by auto antibody-mediated platelet destruction. Although the main cause of ITP remains unclear, but its relationship with some infection was demonstrated. In recent years, many studies have demonstrated improvement of plate...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Payandeh M,Sohrabi N,Zare ME,Kansestani AN,Hashemian AH

更新日期：2012-01-01 00:00:00

abstract：Background:Foetal haemoglobin (HbF) is a major modifying factor influencing sickle cell disease (SCD) severity. Despite this, HbF estimation is not routinely done in Nigeria. The relationship between HbF and SCD severity among affected children is also poorly studied. Methods:In this descriptive cross-sectional study,...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Adeodu OO,Akinlosotu MA,Adegoke SA,Oseni SBA

更新日期：2017-11-01 00:00:00

abstract：Objective:This study focused on the efficacy and safety of thalidomide for patients with β-thalassemia in a multicenter trial. Methods:Patients with non-transfusion-dependent thalassemia (NTDT) or transfusion-dependent thalassemia (TDT), who were unable to pursue conventional therapy with transfusion and chelation, we...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Yang K,Wu Y,Zhou Y,Long B,Lu Q,Zhou T,Wang L,Geng Z,Yin X

更新日期：2020-05-01 00:00:00

abstract：:The recent focus on the potential link between periodontal and cardiovascular disease (PD and CVD) is part of the larger renewed interest on the role of infection and inflammation in the etiology of atherosclerosis and its clinical manifestations. Periodontal Disease is an inflammatory process affecting the periodonti...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Trevisan M,Dorn J

更新日期：2010-10-01 00:00:00

abstract：Background:Although bronchoalveolar lavage (BAL) measurements of galactomannan antigen (GM) seems to be more sensitive than serum testing to detect invasive fungal infection (IFI), a consensus on the most appropriate diagnostic threshold of the BAL GM test is still unclear. Moreover, there is uncertainty as to whether ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Cefalo M,Puxeddu E,Sarmati L,Paterno G,Fontana C,Nasso D,Pane G,De Bellis E,Palmieri R,Buzzati E,Meconi F,Laureana R,Casciani P,Zizzari AG,Rogliani P,de Fabritiis P,Maurillo L,Buccisano F,Cantonetti M,Arcese W,Ven

更新日期：2019-11-01 00:00:00

abstract：:We describe the entire process leading to the start-up of a hematopoietic stem cell transplantation center at the Hiwa Cancer Hospital, in the city of Sulaymaniyah, Kurdistan Iraqi Region. This capacity building project was funded by the Italian Development Cooperation Agency and implemented with the support of the vo...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Majolino I,Othman D,Rovelli A,Hassan D,Rasool L,Vacca M,Abdalrahman N,Abdullah C,Ahmed Z,Ali D,Ali K,Broggi C,Calabretta C,Canesi M,Ciabatti G,Del Fante C,De Sapio E,Dore G,Frigato A,Gabriel M,Ipsevich F,Kareem

更新日期：2017-04-15 00:00:00

abstract：:Peripheral neuropathies are a vast group of diseases with heterogeneous aetiologies, including genetic and acquired causes. Several haematological disorders may cause an impairment of the peripheral nervous system, with diverse mechanisms and variable clinical, electrophysiological and pathological manifestations. In ...

journal_title：Mediterranean journal of hematology and infectious diseases

authors： Sabatelli M,Laurenti L,Luigetti M

更新日期：2018-09-01 00:00:00