Abstract:
:This study investigates the dosimetry and radiobiological model variation when a second photon arc was added to prostate volumetric-modulated arc therapy (VMAT) using the single-arc technique. Dosimetry and radiobiological model comparison between the single-arc and double-arc prostate VMAT plans were performed on five patients with prostate volumes ranging from 29-68.1 cm3. The prescription dose was 78 Gy/39 fractions and the photon beam energy was 6 MV. Dose-volume histogram, mean and maximum dose of targets (planning and clinical target volume) and normal tissues (rectum, bladder and femoral heads), dose-volume criteria in the treatment plan (D99% of PTV; D30%, D50%, V17Gy and V35Gy of rectum and bladder; D5% of femoral heads), and dose profiles along the vertical and horizontal axis crossing the isocenter were determined using the single-arc and double-arc VMAT technique. For comparison, the monitor unit based on the RapidArc delivery method, prostate tumor control probability (TCP), and rectal normal tissue complication probability (NTCP) based on the Lyman-Burman-Kutcher algorithm were calculated. It was found that though the double-arc technique required almost double the treatment time than the single-arc, the double-arc plan provided a better rectal and bladder dose-volume criteria by shifting the delivered dose in the patient from the anterior-posterior direction to the lateral. As the femoral head was less radiosensitive than the rectum and bladder, the double-arc technique resulted in a prostate VMAT plan with better prostate coverage and rectal dose-volume criteria compared to the single-arc. The prostate TCP of the double-arc plan was found slightly increased (0.16%) compared to the single-arc. Therefore, when the rectal dose-volume criteria are very difficult to achieve in a single-arc prostate VMAT plan, it is worthwhile to consider the double-arc technique.
journal_name
J Appl Clin Med Physjournal_title
Journal of applied clinical medical physicsauthors
Chow JC,Jiang Rdoi
10.1120/jacmp.v14i3.4053subject
Has Abstractpub_date
2013-05-06 00:00:00pages
4053issue
3issn
1526-9914journal_volume
14pub_type
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v14i5.4488
更新日期:2013-09-06 00:00:00
abstract:PURPOSE:The target detectability of cone beam computed tomography (CBCT) performed in image-guided radiation therapy (IGRT) was investigated to achieve sufficient image quality for patient positioning over a course of treatment session while maintaining radiation exposure from CBCT imaging as low as reasonably achievab...
journal_title:Journal of applied clinical medical physics
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doi:10.1002/acm2.12306
更新日期:2018-05-01 00:00:00
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i6.5604
更新日期:2015-11-08 00:00:00
abstract:BACKGROUND AND PURPOSE:The purpose of this study of pancreatic cancer patients treated with respiratory-guided stereotactic body radiotherapy (SBRT) on a standard linac was to investigate (a) the intrafractional relationship change (IRC) between a breathing signal and the tumor position, (b) the impact of IRC on the de...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2020-03-01 00:00:00
abstract:PURPOSE:To investigate the daily setup, interfraction motion, variability in the junction areas, and dosimetric effect in craniospinal irradiation (CSI) patients. METHODS:Fifteen CSI patients who had undergone split-field IMRT were followed in the study. Previous, middle, and posttreatment, each target volume position...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2020-08-01 00:00:00
abstract:PURPOSE:The aim of the current study was to evaluate the backscatter dose and energy spectrum from the Lipiodol with flattening filter (FF) and flattening filter-free (FFF) beams. Moreover, the backscatter range, that was defined as the backscatter distance (BD) are revealed. METHODS:6 MVX FF and FFF beams were delive...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12560
更新日期:2019-06-01 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v14i2.4011
更新日期:2013-03-04 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2008-07-14 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2019-07-01 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v13i5.3845
更新日期:2012-09-06 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i6.5317
更新日期:2015-11-08 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2012-05-10 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2017-09-01 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v13i4.3613
更新日期:2012-07-05 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12895
更新日期:2020-07-01 00:00:00
abstract::The case of a 50-year-old man affected by a rhabdomiosarcoma metastatic lesion in the left flank Is reported. The patient was addressed to 50.4 Gy radiotherapy with concomitant chemotherapy in order to locally control the lesion. A Tri-60-Co magnetic resonance hybrid radiotherapy unit was used for treatment delivery a...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12575
更新日期:2019-06-01 00:00:00
abstract::Radiochromic film has become an important tool to verify dose distributions in highly conformal radiation therapy such as IMRT. Recently, a new generation of these films, EBT3, has become available. EBT3 has the same composition and thickness of the sensitive layer of the previous EBT2 films, but its symmetric layer c...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v14i2.4111
更新日期:2013-03-04 00:00:00
abstract::This work introduces a new technology for electron intensity modulation, which uses small area island blocks within the collimating aperture and small area island apertures in the collimating insert. Due to multiple Coulomb scattering, electrons contribute dose under island blocks and lateral to island apertures. By s...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2017-11-01 00:00:00
abstract:OBJECT:The purpose of this study was to compare two methods of stereotactic localization in Gamma Knife treatment planning: cone beam computed tomography (CBCT) or fiducial. While the fiducial method is the traditional method of localization, CBCT is now available for use with the Gamma Knife Icon. This study seeks to ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2019-11-01 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2009-06-02 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2020-04-01 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2016-11-08 00:00:00
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journal_title:Journal of applied clinical medical physics
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更新日期:2015-01-08 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2019-12-01 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2000-04-01 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2015-11-08 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2015-09-08 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2020-10-01 00:00:00