Abstract:
:This study evaluated the basic dosimetric characteristics of a Dynamic Multi Leaf Collimator (DMLC) using a diode detector and film measurements for Intensity Modulated Radiation Therapy Quality Assurance (IMRT QA). The EGSnrc Monte Carlo (MC) simulation system was used for the determination of MLC characteristics. Radiation transmission and abutting leaf leakage relevant to the LinaTech DMLC H were measured using an EDGE detector and EBT3 film. In this study, the BEAMnrc simulation code was used for modeling. The head of Siemens PRIMUS linac (6 MV) with external DMLC H was entered into a BEAMnrc Monte Carlo model using practical dosimetry data. Leaf material density, as well as interleaf and abutting air gaps were determined according to the computed and measured dose profiles. The IMRT QA field was used to evaluate the dose distribution of the simulated DMLC H. According to measurements taken with the EDGE detector and film, the total average measured leakage was 1.60 ± 0.03% and 1.57 ± 0.05%, respectively. For these measurements, abutting leaf transmission was 54.35 ± 1.85% and 53.08 ± 2.05%, respectively. To adapt the simulated leaf dose profiles with measurements, leaf material density, interleaf and abutting air gaps were adjusted to 18 g/cm3 , 0.008 cm and 0.108 cm, respectively. Thus, the total average leakage was estimated to be about 1.59 ± 0.02%. The step-and-shoot IMRT was implemented and 94% agreement was achieved between the film and MC, using 3%-3 mm gamma criteria. The results of this study showed that the dosimetric characteristics of DMLC H satisfied international standards.
journal_name
J Appl Clin Med Physjournal_title
Journal of applied clinical medical physicsauthors
Molazadeh M,Zeinali A,Robatjazi M,Shirazi A,Geraily Gdoi
10.1002/acm2.12055subject
Has Abstractpub_date
2017-03-01 00:00:00pages
113-124issue
2issn
1526-9914journal_volume
18pub_type
杂志文章abstract::Chest wall radiation therapy treatment delivery was monitored using a 5 mm thick radiochromic poly(vinyl alcohol) cryogel that also provided buildup material. The cryogels were used to detect positioning errors and measure the impact of shifts for a chest wall treatment that was delivered to a RANDO phantom. The phant...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v17i5.6148
更新日期:2016-09-08 00:00:00
abstract:PURPOSE:To determine the optimal dose-volume constraint for laryngeal sparing using three commonly employed intensity modulated radiation therapy (IMRT) approaches in patients with oropharyngeal cancer treated to the bilateral neck. MATERIALS AND METHODS:Thirty patients with stage II-IVA oropharynx cancers received de...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.13009
更新日期:2020-12-05 00:00:00
abstract::The purpose of this study is to find the uncertainties in the reconstruction of MR compatible ring-tandem intracavitary applicators of high-dose rate image-based brachytherapy treatment planning using rigid registration of 3D MR and CT image fusion. Tandem and ring reconstruction in MR image based brachytherapy planni...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v15i2.4206
更新日期:2014-03-06 00:00:00
abstract::A new version of progressive resolution optimizer (PRO) with an option of air cavity correction has been implemented for RapidArc volumetric-modulated arc therapy (RA). The purpose of this study was to compare the performance of this new PRO with the use of air cavity correction option (PRO10_air) against the one with...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v14i6.4382
更新日期:2013-11-04 00:00:00
abstract::We assessed interfraction positional variation in pancreatic tumors using daily breath-hold cone-beam computed tomography at end-exhalation (EE) with visual feedback (BH-CBCT). Eleven consecutive patients with pancreatic cancer who underwent BH intensity-modulated radiation therapy with visual feedback were enrolled. ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i2.5123
更新日期:2015-03-08 00:00:00
abstract::The objectives of this project are to quantify the dose reduction effect provided by a lead shield for patients with cardiac implantable electronic devices (CIED) during a clinically realistic radiation treatment on phantom and to provide a simple model of dose estimation to predict dose received by CIED in a wide ran...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i6.5317
更新日期:2015-11-08 00:00:00
abstract::In Winston-Lutz (WL) tests, the isocenter of a linear accelerator (linac) is determined as the intersection of radiation central axes (CAX) from multiple gantry, collimator, and couch angles. It is well known that the CAX can wobble due to mechanical imperfections of the linac. Previous studies suggested that the wobb...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v17i1.5792
更新日期:2016-01-08 00:00:00
abstract::Using a plane-parallel advanced Markus ionization chamber and a stack of water-equivalent solid phantom blocks, percentage surface and build-up doses of Elekta 6 MV flattening filter (FF) and flattening-filter-free (FFF) beams were measured as a function of the phantom depth for field sizes ranging from 2 × 2 to 10 × ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.13094
更新日期:2020-12-01 00:00:00
abstract::This work compares two accelerated partial breast irradiation modalities, MammoSite brachytherapy and three dimensional conformal radiotherapy (3D-CRT), to a new method, SAVI brachytherapy, following NSABP B-39 guidelines. A total of 21 patients treated at UC San Diego with the SAVI device were evaluated in this compa...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v11i1.3021
更新日期:2009-12-03 00:00:00
abstract:PURPOSE:Although breast density is considered a strong risk factor of breast cancer, its quantitative assessment is difficult. To investigate a quantitative method of measuring breast density using dual-energy mammographic imaging with central digital breast tomosynthesis in physically uniform and nonuniform phantoms. ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12618
更新日期:2019-06-01 00:00:00
abstract::Detection and accurate quantification of treatment delivery errors is important in radiation therapy. This study aims to evaluate the accuracy of DVH based QA in quantifying delivery errors. Eighteen previously treated VMAT plans (prostate, H&N, and brain) were randomly chosen for this study. Conventional IMRT deliver...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v17i5.6344
更新日期:2016-09-08 00:00:00
abstract::The purpose of this study was to quantify the intrafraction motion of pediatric patients with brain tumors during radiation therapy and investigate any correlation between motion, use of general anesthesia, and daily treatment duration. 100 pediatric patients with a mean age of 8.5 years (range: 1.0 to 17.8) were incl...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v12i4.3609
更新日期:2011-11-15 00:00:00
abstract::Optimal choice of beam energy in radiation therapy is easy in many well-documented cases, but less obvious in some others. Low-energy beams may provide better conformity around the target than their high-energy counterparts due to reduced lateral scatter, but they also contribute to overdosage of peripheral normal tis...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v10i4.3012
更新日期:2009-09-03 00:00:00
abstract::The main purposes of this study are to: 1) evaluate the accuracy of XiO treatment planning system (TPS) for different dose calculation grid size based on head phan-tom measurements in uniform scanning proton therapy (USPT); and 2) compare the dosimetric results for various dose calculation grid sizes based on real com...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i5.5510
更新日期:2015-09-08 00:00:00
abstract:PURPOSE:This study evaluates the feasibility of lung dose prediction based on target contour and patient anatomy for breast patients treated with proton therapy. METHODS:Fifty-two randomly selected patients were included in the cohort, who were treated to 50.4-66.4 Gy(RBE) to the left (36), right (15), or bilateral (1...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章,随机对照试验
doi:10.1002/acm2.12436
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:To assess the impact of isocenter shifts due to linac gantry and table rotation during cranial stereotactic radiosurgery on D98 , target volume coverage (TVC), conformity (CI), and gradient index (GI). METHODS:Winston-Lutz (WL) checks were performed on two Elekta Synergy linacs. A stereotactic quality assuranc...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12854
更新日期:2020-05-01 00:00:00
abstract::Special attention is required in planning and administering radiation therapy to patients with cardiac implantable electronic devices (CIEDs), such as pacemaker and defibrillator. The range of dose to CIEDs that can induce malfunction is large among CIEDs. Clinically significant defects have been reported at dose as l...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12229
更新日期:2018-01-01 00:00:00
abstract::The objective of this work is the investigation of intense pulsed light (IPL) photoepilation using Monte Carlo simulation to model the effect of the output dosimetry with millisecond exposure used by typical commercial IPL systems. The temporal pulse shape is an important parameter, which may affect the biological tis...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v13i5.3702
更新日期:2012-09-06 00:00:00
abstract::A method to evaluate the electron beam energy constancy by employing the computed radiography (CR) system has been developed. In this method, a right triangular plastic wedge is used to produce a curve of the CR storage phosphor plate signal versus the wedge thickness. The curve, which resembles the percentage depth i...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v10i4.2911
更新日期:2009-10-15 00:00:00
abstract:INTRODUCTION:A previous pilot study has demonstrated the feasibility of a novel image-based approach for remote dosimetric auditing of clinical trials. The approach uses a model to convert in-air acquired intensity modulated radiotherapy (IMRT) images to delivered dose inside a virtual phantom. The model was developed ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12521
更新日期:2019-01-01 00:00:00
abstract::Multileaf collimator (MLC) tracking represents a promising technique for motion management in radiotherapy. However, the conflict between limited leaf speed/acceleration and the demand for tracking fast target motion is now a prominent issue. Conventional MLCs typically have a maximum leaf speed of 3-4 cm/s and a maxi...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12026
更新日期:2017-01-01 00:00:00
abstract::A wide variety of existing combinations of target and filter materials (target/filter combinations) are used in mammography equipment. The patient dose depends on the X-ray quality that is derived from the target/filter combination, and a calibration of the dosimeter that is used in the measurement that corresponds to...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i6.5604
更新日期:2015-11-08 00:00:00
abstract::The aim of this study was to assess the performance of a gantry-mounted detector system and a couch set detector system using a systematic multileaf collimator positional error manually introduced for volumetric-modulated arc therapy. Four head and neck and esophagus VMAT plans were evaluated by measurement using an e...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v15i3.4495
更新日期:2014-05-08 00:00:00
abstract::Part II of this review article presents four case studies for which peak skin doses are calculated following the methods outlined in Part I of this review. The data available in the cases ranges from proprietary dose reports to fluoroscopy time and number of digital acquisition frames only. Flowcharts are provided for...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v13i1.3693
更新日期:2012-01-05 00:00:00
abstract::Continuous arterial spin labeling (CASL) is a technique for performing quantitative perfusion measurements without the need for exogenous contrast agent administration. This technique has seen limited use in the clinic due to problems of poor sensitivity and the potential for artifacts. In addition, CASL requires the ...
journal_title:Journal of applied clinical medical physics
pub_type: 临床试验,杂志文章
doi:10.1120/jacmp.v6i1.2068
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:The GammaPod is a dedicated prone breast stereotactic radiosurgery (SRS) machine composed of 25 cobalt-60 sources which rotate around the breast to create highly conformal dose distributions for boosts, partial-breast irradiation, or neo-adjuvant SRS. We describe the development and validation of a patient-spec...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12778
更新日期:2019-12-01 00:00:00
abstract::The purpose was to study correlations amongst IMRT DVH evaluation points and how their relaxation impacts the overall plan. 100 head-and-neck cancer cases, using the Eclipse treatment planning system with the same protocol, are statisti-cally analyzed for PTV, brainstem, and spinal cord. To measure variations amongst ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v17i6.6411
更新日期:2016-11-08 00:00:00
abstract::As proton therapy becomes increasingly popular, so does the need for Monte Carlo simulation studies involving accurate beam line modeling of proton treatment units. In this study, the 24 beam configurations of the Mevion S250 proton therapy system installed recently at our institution were modeled using the TOolkit fo...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12077
更新日期:2017-05-01 00:00:00
abstract::Highly attenuating radiation treatment couches are no longer useful in the present era of radiotherapy utilizing IMRT and IGRT. Carbon fibers couch tops with its high tensile strength and low density present a useful alternative. The objective of the current study was to quantify the attenuation of megavoltage photons...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v10i3.2979
更新日期:2009-06-02 00:00:00
abstract::The purpose of the present study was to use a kilovoltage imaging device to measure interfractional and intrafractional setup deviations in patients with head-and-neck or brain cancers receiving intensity-modulated radiotherapy (IMRT) treatment. Before and after IMRT treatment, approximately 3 times weekly, 7 patients...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v8i4.2439
更新日期:2007-09-24 00:00:00