Abstract:
BACKGROUND:There is an urgent need to protect children against dengue since this age group is particularly sensitive to the disease. Since dengue vectors are active mainly during the day, a potential target for control should be schools where children spend a considerable amount of their day. School uniforms are the cultural norm in most developing countries, worn throughout the day. We hypothesise that insecticide-treated school uniforms will reduce the incidence of dengue infection in school-aged children. Our objective is to determine the impact of impregnated school uniforms on dengue incidence. METHODS:A randomised controlled trial will be conducted in eastern Thailand in a group of schools with approximately 2,000 students aged 7-18 years. Pre-fabricated school uniforms will be commercially treated to ensure consistent, high-quality insecticide impregnation with permethrin. A double-blind, randomised, crossover trial at the school level will cover two dengue transmission seasons. DISCUSSION:Practical issues and plans concerning intervention implementation, evaluation, analysing and interpreting the data, and possible policy implications arising from the trial are discussed. TRIAL REGISTRATION:clinicaltrial.gov. REGISTRATION NUMBER:NCT01563640.
journal_name
Trialsjournal_title
Trialsauthors
Wilder-Smith A,Byass P,Olanratmanee P,Maskhao P,Sringernyuang L,Logan JG,Lindsay SW,Banks S,Gubler D,Louis VR,Tozan Y,Kittayapong Pdoi
10.1186/1745-6215-13-212subject
Has Abstractpub_date
2012-11-15 00:00:00pages
212issn
1745-6215pii
1745-6215-13-212journal_volume
13pub_type
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