The effectiveness of Tai Chi on the depressive symptom of young adults with subthreshold depression: a study protocol for a randomized controlled trial.

abstract：BACKGROUND:Evidence for benefit of high positive end-expiratory pressure (PEEP) is largely lacking for invasively ventilated, critically ill patients with uninjured lungs. We hypothesize that ventilation with low PEEP is noninferior to ventilation with high PEEP with regard to the number of ventilator-free days and bei...

journal_title：Trials

authors： Algera AG,Pisani L,Bergmans DCJ,den Boer S,de Borgie CAJ,Bosch FH,Bruin K,Cherpanath TG,Determann RM,Dondorp AM,Dongelmans DA,Endeman H,Haringman JJ,Horn J,Juffermans NP,van Meenen DM,van der Meer NJ,Merkus MP,Moenira

更新日期：2018-05-09 00:00:00

abstract：BACKGROUND:Patient and public involvement (PPI) in studies carried out by the UK Medical Research Council Clinical Trials Unit (MRC CTU) at University College London varies by research type and setting. We developed a series of case studies of PPI to document and share good practice. METHODS:We used purposive sampling...

journal_title：Trials

authors： South A,Hanley B,Gafos M,Cromarty B,Stephens R,Sturgeon K,Scott K,Cragg WJ,Tweed CD,Teera J,Vale CL

更新日期：2016-07-29 00:00:00

abstract：BACKGROUND:Recently, clinical observations reported the potential benefit of vagus nerve stimulation (VNS) for pediatric epilepsy. Transcutaneous auricular vagus nerve stimulation (ta-VNS) is a newer non-invasive VNS, making it more accessible for treating pediatric epilepsy, yet there is limited clinical evidence for ...

journal_title：Trials

authors： He W,Wang XY,Zhou L,Li ZM,Jing XH,Lv ZL,Zhao YF,Shi H,Hu L,Su YS,Zhu B

更新日期：2015-08-21 00:00:00

abstract：BACKGROUND:Cardiovascular disease (CVD) is a major contributor to the burden of disease and the number one cause of death worldwide. From 1990 until today, more people died from coronary heart disease than from any other cause. CVD is regularly treated with minimally or non-minimally invasive off- or on-pump cardiothor...

journal_title：Trials

authors： Moza A,Benstoem C,Autschbach R,Stoppe C,Goetzenich A

更新日期：2015-12-02 00:00:00

abstract：BACKGROUND:To evaluate the antiplaque effects of an alcohol-free mouthrinse containing essential oils-Listerine Zero (LZ)-and an alcohol-based essential oils mouthrinse (EO+) compared with a positive control of 0.20% chlorhexidine mouthrinse (CHX) and a negative control of a placebo solution (saline), using an in vivo ...

journal_title：Trials

authors： Marchetti E,Tecco S,Caterini E,Casalena F,Quinzi V,Mattei A,Marzo G

更新日期：2017-03-31 00:00:00

abstract：BACKGROUND:People with decompensated cirrhosis require complex medical care and are often prescribed an intricate and frequently changing medication and lifestyle regimen. However, many patients mismanage their medications or have poor comprehension of their disease and self-management tasks. This can lead to harm, hos...

journal_title：Trials

authors： Hayward KL,Martin JH,Cottrell WN,Karmakar A,Horsfall LU,Patel PJ,Smith DD,Irvine KM,Powell EE,Valery PC

更新日期：2017-07-20 00:00:00

abstract：BACKGROUND:Distal pancreatectomy for benign and malignant tumours is the second most common surgical procedure on the pancreas. Postoperative pancreatic fistulas (POPF) represent the most significant clinical complication, causing prolongation of hospital stay and the need for additional diagnostic and therapeutic proc...

journal_title：Trials

authors： Hassenpflug M,Bruckner T,Knebel P,Diener MK,Büchler MW,Werner J

更新日期：2013-12-14 00:00:00

abstract：OBJECTIVES:To assess the effect of prone positioning therapy on intubation rate in awake patients with COVID-19 and acute respiratory failure. TRIAL DESIGN:This is a two-center parallel group, superiority, randomized (1:1 allocation ratio) controlled trial. PARTICIPANTS:All patients admitted to the Hospital Civil de ...

journal_title：Trials

authors： Ibarra-Estrada MÁ,Marín-Rosales M,García-Salcido R,Aguirre-Díaz SA,Vargas-Obieta A,Chávez-Peña Q,López-Pulgarín JA,Mijangos-Méndez JC,Aguirre-Avalos G

更新日期：2020-11-23 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via the original article. ...

journal_title：Trials

authors： Sheridan R,Martin-Kerry J,Hudson J,Parker A,Bower P,Knapp P

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:There is currently an absence of high-grade evidence regarding the treatment of chronic sciatica (CS). Whilst gabapentin (GBP) and pregabalin (PGB) are both currently used to treat CS, equipoise exists regarding their individual use. In particular, no head-to-head study of GBP and PGB in CS exists. Despite e...

journal_title：Trials

authors： Robertson K,Marshman LAG,Hennessy M,Harriss L,Plummer D

更新日期：2018-01-09 00:00:00

abstract：BACKGROUND:Recently, catheter-based renal sympathetic denervation (RSD) has been verified to be safely used to substantially reduce the levels of blood pressure, left ventricular hypertrophy, sleep apnea severity and norepinephrine spillover, and improve glucose tolerance. All these pathological changes are recognized ...

journal_title：Trials

authors： Qiu M,Yin Y,Shan Q

更新日期：2013-06-11 00:00:00

abstract：BACKGROUND:Hospital mortality for patients with sepsis has recently declined, but sepsis survivors still suffer from significant long-term mortality and morbidity. There are limited data that support effective strategies to address post-discharge management of patients hospitalized with sepsis. METHODS:The Improving M...

journal_title：Trials

authors： Kowalkowski M,Chou SH,McWilliams A,Lashley C,Murphy S,Rossman W,Papali A,Heffner A,Russo M,Burke L,Gibbs M,Taylor SP,Atrium Health ACORN Investigators.

更新日期：2019-11-29 00:00:00

abstract：BACKGROUND:Equipoise and role conflict have been previously identified as important factors in professionals' engagement with trials, inducing behaviours which can impact on recruitment. We explored these phenomena as potential explanations for the low levels of involvement of teenagers and young adults (TYA) with canc...

journal_title：Trials

authors： Hart RI,Hallowell N,Harden J,Jesudason AB,Lawton J

更新日期：2020-01-10 00:00:00

abstract：BACKGROUND:State of the art sedation concepts on intensive care units (ICU) favor propofol for a time period of up to 72 h and midazolam for long-term sedation. However, intravenous sedation is associated with complications such as development of tolerance, insufficient sedation quality, gastrointestinal paralysis, and...

journal_title：Trials

authors： Soukup J,Selle A,Wienke A,Steighardt J,Wagner NM,Kellner P

更新日期：2012-08-10 00:00:00

abstract：BACKGROUND:Most people who stop smoking successfully for a few weeks will return to smoking again in the medium term. There are few effective interventions to prevent this relapse and none used routinely in clinical practice. A previous exploratory meta-analysis suggested that self-help booklets may be effective but re...

journal_title：Trials

authors： Song F,Holland R,Barton GR,Bachmann M,Blyth A,Maskrey V,Aveyard P,Sutton S,Leonardi-Bee J,Brandon TH

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:Chronic musculoskeletal pain (MSP) affects more than 40% of adults aged 50 years and older and is the leading cause of disability in the USA. Older adults with chronic MSP are at risk for analgesic-related side effects, long-term opioid use, and functional decline. Recognizing the burden of chronic MSP, redu...

journal_title：Trials

authors： Platts-Mills TF,McLean SA,Weinberger M,Stearns SC,Bush M,Teresi BB,Hurka-Richardson K,Kroenke K,Kerns RD,Weaver MA,Keefe FJ

更新日期：2020-07-06 00:00:00

abstract：BACKGROUND:A wound that does not heal in the orderly stages of the healing process or does not heal within 3 months is considered a chronic wound. Wound healing is impaired when the wound remains in the inflammatory stage for too long. A range of factors can delay the healing process: imbalance between proteases and pr...

journal_title：Trials

authors： Comino-Sanz IM,López-Franco MD,Castro B,Pancorbo-Hidalgo PL

更新日期：2020-06-08 00:00:00

abstract：BACKGROUND:Individuals who sustain traumatic brain injuries (TBIs) often continue to experience significant impairment of cognitive functions mediated by the prefrontal cortex well into chronic stages of recovery. Traditional brain training programs that focus on improving specific skills fall short of addressing integ...

journal_title：Trials

authors： Krawczyk DC,Marquez de la Plata C,Schauer GF,Vas AK,Keebler M,Tuthill S,Gardner C,Jantz T,Yu W,Chapman SB

更新日期：2013-01-30 00:00:00

abstract：BACKGROUND:In people with chronic obstructive pulmonary disease (COPD), limb-muscle dysfunction is one of the most troublesome systemic manifestations of the disease, which at the functional level is evidenced by reduced strength and endurance of limb muscles. Improving limb-muscle function is an important therapeutic ...

journal_title：Trials

authors： Frykholm E,Klijn P,Saey D,van Hees HWH,Stål P,Sandström T,Sörlin A,Maltais F,Nyberg A

更新日期：2019-01-03 00:00:00

abstract：BACKGROUND:This study aims to evaluate the feasibility and efficacy of a complex health intervention, based on the combination of conventional Western medicine and traditional Chinese medicine (TCM), in an outpatient department of a university hospital for patients with frequent episodic or chronic tension-type headach...

journal_title：Trials

authors： Schiller J,Kellner T,Briest J,Hoepner K,Woyciechowski A,Ostermann A,Korallus C,Sturm C,Weiberlenn T,Jiang L,Egen C,Beissner F,Stiesch M,Karst M,Gutenbrunner C,Fink MG

更新日期：2019-11-08 00:00:00

abstract：BACKGROUND:Neurofeedback has been applied effectively in various areas, especially in the treatment of children with attention-deficit/hyperactivity disorder (ADHD). This study protocol is designed to investigate the effect of slow cortical potential (SCP) feedback and a new form of neurofeedback using near-infrared sp...

journal_title：Trials

authors： Mayer K,Wyckoff SN,Fallgatter AJ,Ehlis AC,Strehl U

更新日期：2015-04-18 00:00:00

abstract：BACKGROUND:Quadriplegia is a severe, catastrophic injury that predominantly affects people early in life, resulting in lifelong physical disability. Obstructive sleep apnoea is a direct consequence of quadriplegia and is associated with neurocognitive deficits, sleepiness and reduced quality of life. The usual treatmen...

journal_title：Trials

authors： Berlowitz DJ,Ayas N,Barnes M,Brown DJ,Cistulli PA,Geraghty T,Graham A,Lee BB,Morris M,O'Donoghue F,Rochford PD,Ross J,Singhal B,Spong J,Wadsworth B,Pierce RJ

更新日期：2013-06-19 00:00:00

abstract：BACKGROUND:Psychodynamic psychotherapy is frequently applied in the treatment of social phobia. Nevertheless, there has been a lack of studies on the transfer of manualized treatments to routine psychodynamic practice. Our study is the first one to examine the effects of additional training in a manualized Short Term P...

journal_title：Trials

authors： Wiltink J,Ruckes C,Haselbacher A,Canterino M,Leichsenring F,Joraschky P,Leweke F,Pöhlmann K,Beutel ME

更新日期：2011-06-08 00:00:00

abstract：BACKGROUND:Visible light (400 to 700 nm) is common in our environment, comprising 44% of total solar radiation and a large component of environmental light exposure. The effects of visible light on skin remain undefined. The red light portion of the visible spectrum (600 to 700 nm) may be used to treat skin diseases as...

journal_title：Trials

authors： Wang EB,Kaur R,Nguyen J,Ho D,Austin E,Maverakis E,Li CS,Hwang ST,Isseroff RR,Jagdeo J

更新日期：2019-03-20 00:00:00

abstract：BACKGROUND:Gastroesophageal reflux disease lowers the quality of life and increases medical costs. Electroacupuncture has been used to ease symptoms and improve gastrointestinal motility in patients with gastroesophageal reflux disease. The main purposes of this study are to evaluate the efficacy and safety of this pro...

journal_title：Trials

authors： Han G,Leem J,Lee H,Lee J

更新日期：2016-05-17 00:00:00

abstract：BACKGROUND:Surgical site infections (SSI) remain one of the most common complications in conventional abdominal surgery with an incidence between 4% and 19% (Sandini et al., Medicine (Baltimore) 95:e4057, 2016) in the literature. It is unclear whether the use of coated suture material for skin closure reduces the risk ...

journal_title：Trials

authors： Matz D,Teuteberg S,Wiencierz A,Soysal SD,Heizmann O

更新日期：2019-07-02 00:00:00

abstract：BACKGROUND:An individualized treatment algorithm (Copenhagen Achilles Rupture Treatment Algorithm (CARTA)) based on the ultrasonographic appearance of an acute Achilles tendon rupture has been developed aiming to select the correct patients for operative and non-operative treatment. The objective of this study is to in...

journal_title：Trials

authors： Hansen MS,Vestermark MT,Hölmich P,Kristensen MT,Barfod KW

更新日期：2020-05-12 00:00:00

abstract：BACKGROUND:Cigarette smoking negatively impacts on maternal and fetal health. Smoking cessation is one of the few interventions capable of improving pregnancy outcomes. Despite the risks, the most effective antenatal model of care for smokers is still unclear, and specific recommendations for screening for fetal growth...

journal_title：Trials

authors： McDonnell BP,Dicker P,Keogan S,Clancy L,Regan C

更新日期：2019-09-03 00:00:00

abstract：BACKGROUND:Depression is a common affliction for young adults, and is associated with a range of adverse outcomes. Cognitive-reminiscence therapy is a brief, structured intervention that has been shown to be highly effective for reducing depressive symptoms, yet to date has not been evaluated in young adult populations...

journal_title：Trials

authors： Hallford DJ,Mellor D

更新日期：2013-10-21 00:00:00

abstract：BACKGROUND:Contrast-induced nephropathy (CIN) is a serious clinical problem associated with increased morbidity and mortality, particularly in patients with chronic renal insufficiency. Although some agents including hydration with saline are being prescribed to prevent renal deterioration in these high risk patients, ...

journal_title：Trials

authors： Park K,Chung WY,Seo JB,Kim SH,Zo JH,Kim MA,Park YB

更新日期：2010-12-20 00:00:00