Abstract:
INTRODUCTION:Vitamin D plays an important role in a broad range of organ functions, including the cardiovascular system. Only one study has tested the association between vitamin D deficiency and arrhythmia and it found no association. The aim of the present study was to evaluate the association between vitamin D deficiency and the type of atrial fibrillation (AF) and complications to AF. MATERIAL AND METHODS:In total, 258 patients were consecutively included from March 2009 to February 2011. All in- and out-patients in the Department of Cardiology at Hvidovre Hospital were invited to participate, provided they had electrocardiographically documented AF. Patients with dementia or terminal illness were excluded. 25 hydroxyvitamin D (25 OHD) was measured with a chemiluminescence assay (Liaison from DiaSorin, Stillwater, Minnesota, USA). RESULTS:No association between vitamin D level and type of AF was found. Furthermore, no association between vitamin D deficiency and ischaemic heart disease, stroke or acute myocardial infarction was found. Vitamin D deficiency was significantly associated with low age (p = 0.02) and gender with a higher proportion of females having the optimal level of 25 OHD (p = 0.0005). CONCLUSION:Other studies have found a beneficial effect of vitamin D on cardiovascular diseases, but we found no association between vitamin D deficiency and the type of AF or complications to AF. Further investigation is necessary to determine whether vitamin D supplementation improves cardiovascular outcomes in patients with AF. FUNDING:The study has received financial support from several private and one public fund. TRIAL REGISTRATION:The study was approved by the National Ethics Committee (Project-ID: H-C-2009-014).
journal_name
Dan Med Jjournal_title
Danish medical journalauthors
Qayyum F,Landex NL,Agner BR,Rasmussen M,Jøns C,Dixen Usubject
Has Abstractpub_date
2012-09-01 00:00:00pages
A4505issue
9issn
2245-1919pii
A4505journal_volume
59pub_type
杂志文章abstract:INTRODUCTION:This study reports our experience with microscopic phonosurgery (PS) of benign lesions of the vocal folds. MATERIAL AND METHODS:During the five-year period from 2003 to 2007, a total of 97 patients had PS for vocal fold polyps (n = 63), vocal fold cysts (n = 17), vocal fold nodules (n = 12) or vocal fold ...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2013-02-01 00:00:00
abstract:INTRODUCTION:The aim of the study is to identify how disease management programmes for patients with a chronic disease work. This issue is explored from the patients' perspective. Specifically, we study how transition and coordination are related to the patient's perception of quality of care, with a particular focus o...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2016-03-01 00:00:00
abstract::Critically ill acute high-risk abdominal surgery patients represent a major challenge to health care providers, with the typical patient being elderly and frail, and with severe and multiple comorbidities. The mortality rate in this population is high, and the postoperative course is characterized by complications, pr...
journal_title:Danish medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2018-02-01 00:00:00
abstract:INTRODUCTION:Atrial fibrillation (AF) is a cardiac epidemic. In this study, we aimed to describe the causes of hospital-isation in an AF population over time and to study how different AF treatment strategies affected hospitalization. MATERIAL AND METHODS:This was an observational study in which long-term follow-up da...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:The use of positron emission tomography with 2-deoxy-2-18F-fluoro-D-glucose integrated with CT (18F-FDG-PET/CT) in oncology is common. Unexpected incidental findings are occasionally recognised and can represent clinically relevant lesions or conditions. This study aims to assess the occurrence, clinical s...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2020-09-07 00:00:00
abstract:INTRODUCTION:Reliable dietary information is crucial for measuring the habitual diet of healthy participants and patients with dyslipidaemia and/or coronary heart disease (CHD). Even so, methods are often complicated and time-consuming for everyone involved. We aimed to validate the new food frequency questionnaire (FF...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2018-11-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to assess the complication rates of total thyroidectomy in a regional hospital setting in Denmark for permanent hypoparathyroidism, recurrent laryngeal nerve palsy and post-operative bleeding. Furthermore, the long-term outcomes in the management of hypoparathyroidism were investi...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2015-11-01 00:00:00
abstract::Heart failure is a complex clinical syndrome and one of the leading causes of morbidity and mortality with a prevalence of 1%-2% of the adult population. The prognosis is poor with a 5-year mortality rate of 50%, which partly can be attributed to the presence of concomitant comorbidity, including neurological and psyc...
journal_title:Danish medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2018-04-01 00:00:00
abstract:INTRODUCTION:Knowledge of trauma patients is often based on US studies. However, these may not be representative of the Scandinavian population. Knowing which trauma patients are at risk of dying might help us target and optimise their treatment. The purpose of this study was to examine the epidemiological characterist...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2014-10-01 00:00:00
abstract::Hip dysplasia and hip joint deformities in general are recognized as possible precursors of osteoarthritic development. Early and correct identification of hip dysplasia is important in order to offer timely joint preserving treatment. In the contemporary literature, several controversies exist, and some of these were...
journal_title:Danish medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2012-06-01 00:00:00
abstract::End-stage liver diseases represent major health problems that are currently treated by liver transplantation. However, given the world-wide shortage of donor livers novel strategies are needed for therapeutic treatment. Adult stem cells have the ability to self-renew and differentiate into the more specialized cell ty...
journal_title:Danish medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2013-05-01 00:00:00
abstract:INTRODUCTION:Colorectal cancer is a common malignant disease, caused by different aetiologies and molecular pathways. Heterogeneous results have been published regarding the association of microsatellite instability and clinicopathological features. The aim of this study was to compare clinicopathological features of m...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2016-02-01 00:00:00
abstract:INTRODUCTION:Volvulus is an axial twist of any part of the gastrointestinal tract along its mesentery. If it goes unattended, it will cause bowel obstruction and bowel ischaemia with gangrene and perforation. The primary treatment is endoscopic desufflation, but the place for elective surgery is controversial. Volvulus...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2013-07-01 00:00:00
abstract:INTRODUCTION:With the increasing use of cross-sectional imaging, the incidence of non-symptomatic pancreatic cystic neoplasms is increasing. Surgical management of pancreatic cystic neoplasms possess significant risks of perioperative morbidity and mortality. Our aim was to evaluate endoscopic ultrasound (EUS)-guided a...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2020-08-01 00:00:00
abstract:INTRODUCTION:Spontaneous reporting of adverse drug reactions (ADRs) is used for continuous risk-benefit evaluation of marketed pharmaceutical products and for signal detection. The Adverse Drug Event Manager (ADEM) is a service offered to clinicians employed at hospitals in the Capital Region of Denmark. The ADEM assis...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:Recently, we established that a group of obese children and adolescents had a higher blood pressure (BP) than a healthy control group. In the present study, we investigate whether the higher BP in the obese group was influenced by BP cuff sizes. METHODS:A total of 104 obese patients aged 10-18 years were ...
journal_title:Danish medical journal
pub_type: 临床试验,杂志文章
doi:
更新日期:2016-01-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to examine the use of quantitative fluorescein angiographic analysis as a means of estimating rates of perfusion of the retina in eyes with a circulatory deficit secondary to carotid artery stenosis. MATERIAL AND METHODS:The study included 21 eyes with ocular ischaemic syndrome (...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2013-10-01 00:00:00
abstract::Strategies to reduce the burden of blood pressure attributable diseases require knowledge of secular trend in PBP and its determinants. The issues were investigated in the Copenhagen City Heart Study. The design of CCHS is a repeated measures study. Such designs are uniquely suited to studying changes of an outcome an...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2017-03-01 00:00:00
abstract:INTRODUCTION:Surveying sexual behaviour of the general population serves to identify key points of preventive interventions, monitor the effect and interpret changes in patterns of disease. Validated questionnaires describing sexual behaviour can be adapted to some extent from other countries, but national adaption, re...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:Infants with bronchopulmonary dysplasia (BPD) are at high risk of developing cardiovascular sequelae in the form of pulmonary hypertension (PH) which significantly increases morbidity and mortality. The aim of this study was to evaluate the incidence of BPD, to identify characteristics associated with BPD ...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2013-08-01 00:00:00
abstract:INTRODUCTION:There is no consensus among hip surgeons in Denmark on how to follow up patients after total hip arthroplasty (THA). Agreement on the need for radiographic examinations is also lacking. The purpose of this study was to evaluate if routine outpatient post-operative radiographs, obtained three and 12 months ...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2013-04-01 00:00:00
abstract:INTRODUCTION:This study explored whether health-related quality of life (HRQOL) changes following Roux-en-Y gastric bypass surgery were associated with identifiable socio-demographic or clinical characteristics, and it examined the impact on health outcomes of changes in the Danish criteria for bariatric surgery. MATE...
journal_title:Danish medical journal
pub_type: 临床试验,杂志文章
doi:
更新日期:2014-07-01 00:00:00
abstract::Excessive health anxiety, still designated as hypochondriasis in ICD-10, refers to worries and anxiety about harbouring serious illness. It is common in both primary and secondary health care with prevalence rates up to 9% and causes great suffering for the individual as well as high health care costs when untreated. ...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2017-05-01 00:00:00
abstract:INTRODUCTION:Total mesorectal excision (TME) is the standard surgical treatment for mid and low rectal cancer. The procedure is performed by open, laparoscopic or robotic approaches. Transanal TME (TaTME) is a new procedure that potentially solves some difficulties in the pelvic part of the dissection. We aimed to eval...
journal_title:Danish medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2015-07-01 00:00:00
abstract:INTRODUCTION:Marfan syndrome is an autosomal, dominantly inherited disorder of the connective tissue. We report the clinical data and results of a genetic analysis of a large Danish Marfan family. METHODS:Sanger sequencing of FBN1 was initially performed on genomic DNA from the index patient. Subsequently, four affect...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2014-11-01 00:00:00
abstract:INTRODUCTION:Clinical practice does not reflect current clinical guidelines recommending an early multimodal non-surgical treatment for knee and hip osteoarthritis (OA). The purpose of this study was to examine the feasibility of such an initiative (Good Life with osteoArthritis in Denmark (GLA:D) in persons with mild ...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2012-12-01 00:00:00
abstract:INTRODUCTION:Age and comorbidity are associated with length of stay (LOS) and mortality. Our aim was to compare acutely ill elderly medical patients in geriatric care with general medical care, and to examine the effects of comprehensive geriatric assessment (CGA). MATERIAL AND METHODS:In an observational study, we us...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2012-06-01 00:00:00
abstract::The epidemiology and prognosis of ''fainting'' or syncope has puzzled physicians over the years. Is fainting dangerous? This is a question often asked by the patient--and the answer is ''it depends on a lot of things''. The diverse pathophysiology of syncope and the underlying comorbidites of the patients play an esse...
journal_title:Danish medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2013-09-01 00:00:00
abstract:INTRODUCTION:The Danish Adult Diabetes Database (DADD) annually reports a quality indicator for lipid-lowering treatment of type 2 diabetes mellitus (T2DM) patients. This retrospective cohort study aims to A) investigate the reasons for inadequate or lacking lipid-lowering treatment and to B) assess the validity of the...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2018-09-01 00:00:00
abstract::Ischemia-reperfusion injuries occur when the blood supply to an organ or tissue is temporarily cut-off and then restored. Even though the restoration of blood flow is absolutely essential in preventing tissue death, the reperfusion of oxygenated blood to the oxygen-deprived areas may in itself augment the tissue damag...
journal_title:Danish medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2015-04-01 00:00:00