Endoscopic ultrasound-guided ablation is a promising treatment for pancreatic cystic neoplasms - a systematic review.

Abstract:

INTRODUCTION:With the increasing use of cross-sectional imaging, the incidence of non-symptomatic pancreatic cystic neoplasms is increasing. Surgical management of pancreatic cystic neoplasms possess significant risks of perioperative morbidity and mortality. Our aim was to evaluate endoscopic ultrasound (EUS)-guided ablation as a non-operative treatment of pancreatic cystic neoplasms. METHODS:We performed a literature search in MEDLINE, Embase and Scopus. All clinical studies examining the safety and efficacy of EUS-guided pancreatic cyst ablation with radiofrequency, sclerosants, ethanol, chemotherapeutics or a combination hereof were included. RESULTS:A total of 17 studies were included. We found that EUS-guided pancreatic cyst ablation was feasible with complete resolution in up to 86% of cases after 3-12 months. The modality with the most promising results after 3-12 months was chemoablation with complete resolution rates ranging from 46 to 79% (median 64%). The most appropriate follow-up period was estimated to be 12 months. The risk of serious adverse events including pancreatitis was approximately 16%. Very few cyst recurrences have been documented following complete resolution after cyst ablation. CONCLUSIONS:EUS-guided cyst ablation of pancreatic cystic lesions seems effective and safe as an alternative to surgical resection in patients who are unfit for surgery or who have low-risk pancreatic cystic neoplasms.

journal_name

Dan Med J

journal_title

Danish medical journal

authors

Olsen GA,Aalling L,Karstensen JG

subject

Has Abstract

pub_date

2020-08-01 00:00:00

issue

8

issn

2245-1919

pii

A01200019

journal_volume

67

pub_type

杂志文章
  • Discrepancy between information reported by the victims of sexual assaults and clinical forensic findings.

    abstract:INTRODUCTION:From the clinical forensic examination reports made at the Department of Forensic Medicine, the University of Copenhagen, in 2007 concerning rape, attempted rape and sexual assault (RAS), information about the assault, including both violence and the perpetrator's line of sexual action was extracted, analy...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Scherer S,Hansen SH,Lynnerup N

    更新日期:2014-09-01 00:00:00

  • Diagnostic and therapeutic challenges in superficial CNS siderosis.

    abstract:INTRODUCTION:Superficial CNS siderosis was previously almost unknown but is now diagnosed with increasing frequency owing to magnetic resonance imaging. Patients may present with sensory deafness, gait ataxia, various sensorimotor signs and, eventually, cognitive decline. They typically have a history of traumatic brai...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Kondziella D,Lindelof M,Haziri D,Larsen VA,Kruse A

    更新日期:2015-05-01 00:00:00

  • Prevalence of sarcopenia in a Danish geriatric out-patient population.

    abstract:INTRODUCTION:The prevalence of sarcopenia varies extensively depending on the definitions and studied populations. The aim of this study was to assess the prevalence of sarcopenia in a Danish geriatric out-patient population using criteria from the European Working Group on Sarcopenia (EWGSOP). METHODS:Patients referr...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Christensen MG,Piper KS,Dreier R,Suetta C,Andersen HE

    更新日期:2018-06-01 00:00:00

  • Everolimus as adjunctive treatment in tuberous sclerosis complex-associated epilepsy in children.

    abstract:INTRODUCTION:Tuberous sclerosis complex (TSC) is a rare autosomal dominant multi-organ disease. In TSC, epilepsy is frequent and often treatment refractory. Dysfunction of the tumour-suppressing hamartin/tuberin complex leads to an over-activated mammalian target of rapamycin (mTOR) signalling pathway and uncontrolled ...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Svarrer EMM,Fischer CM,Frederiksen MG,Born AP,Hoei-Hansen CE

    更新日期:2019-12-01 00:00:00

  • Outpatient hemithyroidectomy for benign thyroid disease.

    abstract:INTRODUCTION:Hemithyroidectomy for benign thyroid disease has traditionally been considered an inpatient procedure due to concerns about post-operative complications, in particular the risk of post-thyroidectomy bleeding (PTB). Hemithyroidectomy in an outpatient setting has not yet been evaluated in a Danish context. T...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Jeppesen K,Skjøt-Arkil H,Moos C,Nielsen SH

    更新日期:2020-09-29 00:00:00

  • Deep neuromuscular blockade and low insufflation pressure during laparoscopic hysterectomy.

    abstract:INTRODUCTION:Establishment of sufficient muscle relaxation is essential in laparoscopic surgery. During laparoscopy, surgeons can experience abdominal contractions in their patients. Deep neuromuscular block (NMB) has the potential to prevent such episodes. In this study, we explored if deep NMB reduces the incidence o...

    journal_title:Danish medical journal

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Madsen MV,Istre O,Springborg HH,Staehr-Rye AK,Rosenberg J,Lund J,Gätke MR

    更新日期:2017-05-01 00:00:00

  • Psychiatric claims to the Danish Patient Insurance Association have low recognition percentages.

    abstract:INTRODUCTION:Since 1992 the Danish Patient Insurance Association (DPIA) has been receiving claims from patients who had suffered an injury during examination or treatment in Danish healthcare. We have presently collected more than 85,000 patient cases in our database, which we make accessible to research that can promo...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Steinø P,Jørgensen CB,Christoffersen JK

    更新日期:2013-08-01 00:00:00

  • Abdominal auscultation does not provide clear clinical diagnoses.

    abstract:INTRODUCTION:Abdominal auscultation is a part of the clinical examination of patients, but the determining factors in bowel sound evaluation are poorly described. The aim of this study was to assess inter- and intra-observer agreement in physicians' evaluation of pitch, intensity and quantity in abdominal auscultation....

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Durup-Dickenson M,Christensen MK,Gade J

    更新日期:2013-05-01 00:00:00

  • Danish survey of acetabular component positioning practice during primary total hip arthroplasty.

    abstract:INTRODUCTION:The Lewinnek and Callanan "safe zones" have been widely used to minimise the dislocation fre-quency in total hip arthroplasty (THA), but recent studies have questioned the association between "safe zones" and lower dislocation rates. The purpose of this study was to investigate: 1) if hip surgeons agree on...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Cotong D,Troelsen A,Husted H,Gromov K

    更新日期:2017-04-01 00:00:00

  • Phonosurgery of vocal fold polyps, cysts and nodules is beneficial.

    abstract:INTRODUCTION:This study reports our experience with microscopic phonosurgery (PS) of benign lesions of the vocal folds. MATERIAL AND METHODS:During the five-year period from 2003 to 2007, a total of 97 patients had PS for vocal fold polyps (n = 63), vocal fold cysts (n = 17), vocal fold nodules (n = 12) or vocal fold ...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Jensen JB,Rasmussen N

    更新日期:2013-02-01 00:00:00

  • Women referred for occupational risk assessment in pregnancy have no increased risk of adverse obstetric outcomes.

    abstract:INTRODUCTION:Our aim was to study the association between pregnant women's referral status for occupational risk assessment, and their risk of preterm delivery (< 37 weeks), low birth weight (LBW) (< 2,500 g) and small for gestational age (SGA). METHODS:In a cohort study, 1,202 deliveries among pregnant women referred...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Bidstrup SB,Kaerlev L,Thulstrup AM,Bonde JP

    更新日期:2015-08-01 00:00:00

  • Prevention of post-operative anaemia in hip and knee arthroplasty--a systematic review.

    abstract:INTRODUCTION:Patient blood management strategies for total hip and knee arthroplasty are controversial. They range from pre-operative haemoglobin optimisation to intra- and post-operative interventions. The aim of this study was to assess the various treatment modalities with respect to blood loss, haemoglobin levels a...

    journal_title:Danish medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Khan N,Troelsen A,Husted H

    更新日期:2015-12-01 00:00:00

  • Clavicle fractures may be conservatively treated with acceptable results - a systematic review.

    abstract:INTRODUCTION:The optimal treatment of acute, displaced midshaft clavicle fractures is controversial. Despite lack of compelling evidence towards superior results after primary surgery, it seems that more and more patients are treated surgically. The aim of this study was to investigate which treatment modality should b...

    journal_title:Danish medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Ban I,Branner U,Holck K,Krasheninnikoff M,Troelsen A

    更新日期:2012-07-01 00:00:00

  • Translation and linguistic validation of the Bronchiectasis Health Questionnaire (BHQ) into Danish.

    abstract:INTRODUCTION:Patients with bronchiectasis suffer from breathlessness, cough and sputum production, which impairs quality of life. The Bronchiectasis Health Questionnaire (BHQ), a short and disease-specific questionnaire, has previously been developed and validated in English. The aim of this study was to translate and ...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Gissel TN,Hvass M,Fly J,Børsting K,Birring SS,Spinou A,Weinreich UM

    更新日期:2020-03-01 00:00:00

  • Neoadjuvant chemotherapy for primary operable breast cancer.

    abstract:INTRODUCTION:Neoadjuvant chemotherapy (NACT) has been found useful in downstaging tumours in women with primary operable breast cancer without increasing mortality. As a result of several studies supporting this, the Danish Breast Cancer Cooperative Group implemented new guidelines for the treatment of primary operable...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Halberg AK,Gravesen CD,Cold S,Jensen JD

    更新日期:2020-11-04 00:00:00

  • Oxidative and inflammatory biomarkers of ischemia and reperfusion injuries.

    abstract::Ischemia-reperfusion injuries occur when the blood supply to an organ or tissue is temporarily cut-off and then restored. Even though the restoration of blood flow is absolutely essential in preventing tissue death, the reperfusion of oxygenated blood to the oxygen-deprived areas may in itself augment the tissue damag...

    journal_title:Danish medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Halladin NL

    更新日期:2015-04-01 00:00:00

  • Danish patients are positive towards fees for non-attendance in public hospitals. A qualitative study.

    abstract:INTRODUCTION:Patients' non-attendance is a significant problem in modern healthcare. Non-attendance delays treatment, reduces efficiency and increases healthcare costs. For several years, the introduction of financial incentives such as a non-attendance fee has been discussed in Denmark. Set in the context of a tax-fin...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Lou S,Frumer M,Olesen S,Nielsen AH,Væggemose U

    更新日期:2016-07-01 00:00:00

  • Telephone consultation as a substitute for face-to-face consultation during the COVID-19 pandemic.

    abstract:INTRODUCTION:The health authorities have recommended that face-to-face consultations be substituted by telephone consultations to reduce the risk of virus transmission in out-patient clinics during the coronavirus disease 2019 (COVID-19) pandemic. The aim of the present study was to assess the frequency of such telepho...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Wolthers TO,Wolthers OD

    更新日期:2020-06-23 00:00:00

  • Asymptomatic body packers should be treated conservatively.

    abstract:INTRODUCTION:Body packing takes advantage of the human storage capacity within the alimentary tract. Body packing is used for the smuggling of drugs such as heroin, cocaine, amphetamine, hashish and ecstasy. Most body packers are asymptomatic. However, packets may rupture or obstruct the alimentary tract. Preventive su...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Glovinski PV,Lauritsen ML,Bay-Nielsen M,Brandstrup B,Bisgaard T

    更新日期:2013-11-01 00:00:00

  • Inadequate follow-up after tracheostomy and intensive care.

    abstract:INTRODUCTION:When patients are transferred from intensive care units (ICUs) to general wards with a tracheostomy in situ, there is a risk of suboptimal care and increased morbidity. The aim of this study was to elucidate the management of patients with a tracheostomy in situ at discharge from the ICU to the ward. MATE...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Mondrup F,Skjelsager K,Madsen KR

    更新日期:2012-08-01 00:00:00

  • Effects of telemedicine in the treatment of patients with type 2 diabetes--a study protocol.

    abstract:INTRODUCTION:Despite rehabilitation programmes offered to all patients with newly diagnosed type 2 diabetes in Denmark, a number of patients either never accomplish good diabetes regulation or the regulation deteriorates with time. Therefore, new approaches are needed. The aim of the present study is to examine whether...

    journal_title:Danish medical journal

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Hansen CR,Perrild H,Koefoed BG,Faurschou P,Høst D,Zander M

    更新日期:2013-12-01 00:00:00

  • Non-survivors after admission to trauma centre.

    abstract:INTRODUCTION:Knowledge of trauma patients is often based on US studies. However, these may not be representative of the Scandinavian population. Knowing which trauma patients are at risk of dying might help us target and optimise their treatment. The purpose of this study was to examine the epidemiological characterist...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Mikkelsen R,Møller Hansen O,Brink O

    更新日期:2014-10-01 00:00:00

  • A novel FBN1 variant in a large Marfan family with high penetrance of aortic dissection or rupture.

    abstract:INTRODUCTION:Marfan syndrome is an autosomal, dominantly inherited disorder of the connective tissue. We report the clinical data and results of a genetic analysis of a large Danish Marfan family. METHODS:Sanger sequencing of FBN1 was initially performed on genomic DNA from the index patient. Subsequently, four affect...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Rasmussen M,Pedersen SF,Sunde L,Andersen NH,Ostergaard JR,Lildballe DL

    更新日期:2014-11-01 00:00:00

  • Experience from a COVID-19 first-line referral clinic in Greater Copenhagen.

    abstract:INTRODUCTION:Due to the coronavirus disease 2019 (COVID-19) exposure in Denmark, first-line referral centres were established to handle all patients suspected of COVID-19 or other upper respiratory tract infection. Here we report the first experiences from a first-line referral centre from Amager-Hvidovre Hospital, sit...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Kronborg TM,Kimer N,Junker AE,Werge MP,Gluud LL,Ytting H

    更新日期:2020-08-07 00:00:00

  • Possible adverse effects of the quadrivalent human papillomavirus vaccine in the Region of Southern Denmark: a retrospective, descriptive cohort study.

    abstract:INTRODUCTION:Since the introduction of the quadrivalent human papillomavirus vaccine, young girls and women have reported a broad range of symptoms. These have been described as possible adverse effects of the vaccine. In this study, we describe demographic characteristics, symptomatology, clinical and laboratory test ...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Cramon C,Poulsen CL,Hartling UB,Holden IK,Johansen IS

    更新日期:2017-07-01 00:00:00

  • Sudden cardiac death in young Danes.

    abstract::Sudden Cardiac Death (SCD) in the young (aged 1-35 years), although presumably rare, is always a tragic and devastating event often occurring in apparently healthy persons. Through the last decades, research have been undertaken to estimate the incidence rate and underlying causes of these deaths. However, because aut...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Winkel BG

    更新日期:2012-02-01 00:00:00

  • Transanal total mesorectal excision--a systematic review.

    abstract:INTRODUCTION:Total mesorectal excision (TME) is the standard surgical treatment for mid and low rectal cancer. The procedure is performed by open, laparoscopic or robotic approaches. Transanal TME (TaTME) is a new procedure that potentially solves some difficulties in the pelvic part of the dissection. We aimed to eval...

    journal_title:Danish medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Bjørn MX,Perdawood SK

    更新日期:2015-07-01 00:00:00

  • Risk of malignancy in fine-needle aspiration biopsy in patients with thyroid nodules.

    abstract:INTRODUCTION:Fine-needle aspiration biopsy (FNAB) is the cornerstone of thyroid nodule evaluation. In most cases, FNAB can discriminate between benign and malignant disease. In other cases, it is only indicative of malignancy and the results are considered "suspicious". In Denmark, thyroid FNAB results are categorised ...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Egset AV,Holm C,Larsen SR,Nielsen SH,Bach J,Helweg-Larsen JP,Larsen LV,Wanscher JH,Godballe C

    更新日期:2017-02-01 00:00:00

  • Treatment of hypoglycaemic diabetics in a prehospital setting is safe.

    abstract:INTRODUCTION:Patients with diabetes suffering from hypoglycaemia may be treated by a Mobile Emergency Care Unit (MECU) and are often released at the scene following treatment. Some of these patients experience secondary hypoglycaemia and require renewed treatment or admission to hospital. The present study was initiate...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Hatting NP,Mikkelsen S

    更新日期:2015-04-01 00:00:00

  • Surgeon-performed ultrasonography.

    abstract::Surgeons are increasingly using ultrasonography (US) in their clinical management of patients. However, US is a very user-dependent imaging modality and proper skills of the US operator are needed to ensure quality in patient care. This thesis explores the validity evidence for assessment of competence in abdominal an...

    journal_title:Danish medical journal

    pub_type: 杂志文章

    doi:

    authors: Todsen T

    更新日期:2017-11-01 00:00:00