Abstract:
INTRODUCTION:With the increasing use of cross-sectional imaging, the incidence of non-symptomatic pancreatic cystic neoplasms is increasing. Surgical management of pancreatic cystic neoplasms possess significant risks of perioperative morbidity and mortality. Our aim was to evaluate endoscopic ultrasound (EUS)-guided ablation as a non-operative treatment of pancreatic cystic neoplasms. METHODS:We performed a literature search in MEDLINE, Embase and Scopus. All clinical studies examining the safety and efficacy of EUS-guided pancreatic cyst ablation with radiofrequency, sclerosants, ethanol, chemotherapeutics or a combination hereof were included. RESULTS:A total of 17 studies were included. We found that EUS-guided pancreatic cyst ablation was feasible with complete resolution in up to 86% of cases after 3-12 months. The modality with the most promising results after 3-12 months was chemoablation with complete resolution rates ranging from 46 to 79% (median 64%). The most appropriate follow-up period was estimated to be 12 months. The risk of serious adverse events including pancreatitis was approximately 16%. Very few cyst recurrences have been documented following complete resolution after cyst ablation. CONCLUSIONS:EUS-guided cyst ablation of pancreatic cystic lesions seems effective and safe as an alternative to surgical resection in patients who are unfit for surgery or who have low-risk pancreatic cystic neoplasms.
journal_name
Dan Med Jjournal_title
Danish medical journalauthors
Olsen GA,Aalling L,Karstensen JGsubject
Has Abstractpub_date
2020-08-01 00:00:00issue
8issn
2245-1919pii
A01200019journal_volume
67pub_type
杂志文章abstract:INTRODUCTION:From the clinical forensic examination reports made at the Department of Forensic Medicine, the University of Copenhagen, in 2007 concerning rape, attempted rape and sexual assault (RAS), information about the assault, including both violence and the perpetrator's line of sexual action was extracted, analy...
journal_title:Danish medical journal
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更新日期:2014-09-01 00:00:00
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pub_type: 杂志文章,评审
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doi:
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journal_title:Danish medical journal
pub_type: 杂志文章
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更新日期:2020-11-04 00:00:00
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doi:
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doi:
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