Abstract:
INTRODUCTION:Atrial fibrillation (AF) is a cardiac epidemic. In this study, we aimed to describe the causes of hospital-isation in an AF population over time and to study how different AF treatment strategies affected hospitalization. MATERIAL AND METHODS:This was an observational study in which long-term follow-up data were collected from hospital records, discharge papers and diagnostic codes. The study population (n = 156) was observed over a total period of ten years which was divided into two successive observation periods (OP), OP1 and OP2. Fourteen endpoints of cardiovascular hospitalisations were evaluated. RESULTS:The causes of hospitalisation shifted over time. We observed a lower proportion of admissions due to AF in OP2 (63%) than in OP1 (87%) and a higher proportion of admissions due to congestive heart failure (16% versus 3%) and of days of inpatient care due to ischaemic stroke (25% versus 7%). Persistent AF where sinus rhythm was pursued was associated with a four-fold increase in the risk of hospitalisation (multivariate Poisson analysis, rate ratio 3.97, 95% confidence interval 2.73-5.76, p < 0.0001) compared with accepted permanent AF. CONCLUSION:Over time, the causes of hospitalisation in an AF population shifted from AF relapse to the most frequent complications of AF, ischaemic stroke and congestive heart failure. In this observational study, patients treated with rhythm control were more frequently hospitalised than patients treated with rate control. FUNDING:not relevant. TRIAL REGISTRATION:not relevant.
journal_name
Dan Med Jjournal_title
Danish medical journalauthors
Qvist JF,Sørensen PH,Dixen Usubject
Has Abstractpub_date
2014-01-01 00:00:00pages
A4765issue
1issn
2245-1919pii
A4765journal_volume
61pub_type
杂志文章abstract:BACKGROUND:High levels of pro-inflammatory cytokines are present in the gut of patients with inflammatory bowel disease (IBD) and have a crucial role in the dysfunction of mucosal homeostasis. Caudal-related homeobox transcription factor 2 (CDX2) is an essential regulator of intestinal epithelium homeostasis. When expr...
journal_title:Danish medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION:Fine-needle aspiration biopsy (FNAB) is the cornerstone of thyroid nodule evaluation. In most cases, FNAB can discriminate between benign and malignant disease. In other cases, it is only indicative of malignancy and the results are considered "suspicious". In Denmark, thyroid FNAB results are categorised ...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2017-02-01 00:00:00
abstract:INTRODUCTION:Infants with bronchopulmonary dysplasia (BPD) are at high risk of developing cardiovascular sequelae in the form of pulmonary hypertension (PH) which significantly increases morbidity and mortality. The aim of this study was to evaluate the incidence of BPD, to identify characteristics associated with BPD ...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2013-08-01 00:00:00
abstract::Asthma and allergies are today the most common chronic diseases in children and the leading causes of school absences, chronic medication usage, emergency department visits and hospitalizations, which affect all members of the family and represent a significant societal and scientific challenge. These highly prevalent...
journal_title:Danish medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2016-08-01 00:00:00
abstract:INTRODUCTION:A routine follow-up urine sample (FUS) in the form of a midstream urine sample (MSU) is recommended after treatment for urinary tract infection (UTI) according to the Danish Paediatric Society (DPS) and "Lægehåndbogen" published by Danish Regions. We studied the effect of FUS with a focus on patients witho...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:The treatment strategy for appendiceal mass is controversial, ranging from operation or image-guided drainage to conservative treatment with or without antibiotics. The aim of this study was to assess the various treatment modalities with respect to complications and treatment failure. METHODS:The analysi...
journal_title:Danish medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2014-08-01 00:00:00
abstract::Strategies to reduce the burden of blood pressure attributable diseases require knowledge of secular trend in PBP and its determinants. The issues were investigated in the Copenhagen City Heart Study. The design of CCHS is a repeated measures study. Such designs are uniquely suited to studying changes of an outcome an...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2017-03-01 00:00:00
abstract::Both non-pathological psychological stress states and mental disorders are associated with molecular, cellular and epidemiological signs of accelerated aging. Oxidative stress on nucleic acids is a critical component of cellular and organismal aging, and a suggested pathogenic mechanism in several age-related somatic ...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2013-07-01 00:00:00
abstract::Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by pain, swelling and progressive destruction of the joints leading to loss of function and invalidity. The bone destruction in RA is characterised by two distinct features: structural joint damage and hand bone loss, and their prevention is an im...
journal_title:Danish medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2018-03-01 00:00:00
abstract:INTRODUCTION:Abdominal auscultation is a part of the clinical examination of patients, but the determining factors in bowel sound evaluation are poorly described. The aim of this study was to assess inter- and intra-observer agreement in physicians' evaluation of pitch, intensity and quantity in abdominal auscultation....
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2013-05-01 00:00:00
abstract:INTRODUCTION:The aim was to illustrate current use of temporary pacing (TP) in Denmark by replicating a questionnaire study from 1986 and to compare the results of the two studies. MATERIAL AND METHODS:The questionnaire was sent to Danish hospitals treating patients with acute myocardial infarction (AMI). To illustrat...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2012-02-01 00:00:00
abstract:INTRODUCTION:Reliable dietary information is crucial for measuring the habitual diet of healthy participants and patients with dyslipidaemia and/or coronary heart disease (CHD). Even so, methods are often complicated and time-consuming for everyone involved. We aimed to validate the new food frequency questionnaire (FF...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2018-11-01 00:00:00
abstract:INTRODUCTION:Age and comorbidity are associated with length of stay (LOS) and mortality. Our aim was to compare acutely ill elderly medical patients in geriatric care with general medical care, and to examine the effects of comprehensive geriatric assessment (CGA). MATERIAL AND METHODS:In an observational study, we us...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2012-06-01 00:00:00
abstract:INTRODUCTION:Extant studies on arterial trauma originate from outside Denmark and their findings may therefore not apply to a Danish setting. The aim of the present study was to investigate the long-term mortality and clinical characteristics of patients with arterial trauma treated in Odense University Hospital (OUH)....
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2015-03-01 00:00:00
abstract:INTRODUCTION:Marfan syndrome is an autosomal, dominantly inherited disorder of the connective tissue. We report the clinical data and results of a genetic analysis of a large Danish Marfan family. METHODS:Sanger sequencing of FBN1 was initially performed on genomic DNA from the index patient. Subsequently, four affect...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2014-11-01 00:00:00
abstract:INTRODUCTION:The aim of the study is to identify how disease management programmes for patients with a chronic disease work. This issue is explored from the patients' perspective. Specifically, we study how transition and coordination are related to the patient's perception of quality of care, with a particular focus o...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2016-03-01 00:00:00
abstract:INTRODUCTION:With the increasing use of cross-sectional imaging, the incidence of non-symptomatic pancreatic cystic neoplasms is increasing. Surgical management of pancreatic cystic neoplasms possess significant risks of perioperative morbidity and mortality. Our aim was to evaluate endoscopic ultrasound (EUS)-guided a...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2020-08-01 00:00:00
abstract:INTRODUCTION:The health authorities have recommended that face-to-face consultations be substituted by telephone consultations to reduce the risk of virus transmission in out-patient clinics during the coronavirus disease 2019 (COVID-19) pandemic. The aim of the present study was to assess the frequency of such telepho...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2020-06-23 00:00:00
abstract:INTRODUCTION:Patients with bronchiectasis suffer from breathlessness, cough and sputum production, which impairs quality of life. The Bronchiectasis Health Questionnaire (BHQ), a short and disease-specific questionnaire, has previously been developed and validated in English. The aim of this study was to translate and ...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2020-03-01 00:00:00
abstract::Today, sentinel lymph node dissection (SLND) has replaced axillary lymph node dissection (ALND) as standard procedure for staging of the axilla in the treatment of breast cancer. SLND can accurately stage the axilla by removing on average only two lymph nodes. Only in case of metastatic spread to sentinel nodes an ALN...
journal_title:Danish medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2012-07-01 00:00:00
abstract:INTRODUCTION:Due to the coronavirus disease 2019 (COVID-19) exposure in Denmark, first-line referral centres were established to handle all patients suspected of COVID-19 or other upper respiratory tract infection. Here we report the first experiences from a first-line referral centre from Amager-Hvidovre Hospital, sit...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2020-08-07 00:00:00
abstract:INTRODUCTION:Recent studies have reported an asso-ciation between the day of week of surgery and post-operative mortality, meaning that patients undergoing surgery at the end of the week or during weekends may be at higher risk. The aim of this study was to investigate the influence of the day of week of surgery on mor...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2019-07-01 00:00:00
abstract::Kidney cancer (Renal Cell Carcinoma (RCC)) is one of the most deadly malignancies due to frequent late diagnosis and poor treatment options. Histologically, RCC embraces a wide variety of different subtypes with the clear cell variant (ccRCC) being the most common, accounting for 75-90% of all RCCs. At present, the su...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2017-10-01 00:00:00
abstract:INTRODUCTION:The prevalence of sarcopenia varies extensively depending on the definitions and studied populations. The aim of this study was to assess the prevalence of sarcopenia in a Danish geriatric out-patient population using criteria from the European Working Group on Sarcopenia (EWGSOP). METHODS:Patients referr...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2018-06-01 00:00:00
abstract::Ischemia-reperfusion injuries occur when the blood supply to an organ or tissue is temporarily cut-off and then restored. Even though the restoration of blood flow is absolutely essential in preventing tissue death, the reperfusion of oxygenated blood to the oxygen-deprived areas may in itself augment the tissue damag...
journal_title:Danish medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2015-04-01 00:00:00
abstract:INTRODUCTION:The Lewinnek and Callanan "safe zones" have been widely used to minimise the dislocation fre-quency in total hip arthroplasty (THA), but recent studies have questioned the association between "safe zones" and lower dislocation rates. The purpose of this study was to investigate: 1) if hip surgeons agree on...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2017-04-01 00:00:00
abstract::The overall aim of this thesis was to validate the new concept of the Fertility Assessment and Counselling (FAC) Clinic at Rigshospitalet. The intention was to: explore the prognostic value of fertility risk factors by a risk score and provide an estimate of female fecundity, to quantify the impact of oral contracepti...
journal_title:Danish medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2016-10-01 00:00:00
abstract:INTRODUCTION:From the clinical forensic examination reports made at the Department of Forensic Medicine, the University of Copenhagen, in 2007 concerning rape, attempted rape and sexual assault (RAS), information about the assault, including both violence and the perpetrator's line of sexual action was extracted, analy...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2014-09-01 00:00:00
abstract:INTRODUCTION:Volvulus is an axial twist of any part of the gastrointestinal tract along its mesentery. If it goes unattended, it will cause bowel obstruction and bowel ischaemia with gangrene and perforation. The primary treatment is endoscopic desufflation, but the place for elective surgery is controversial. Volvulus...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2013-07-01 00:00:00
abstract:INTRODUCTION:In order to optimise the selection process for admission to specialist training in family medicine, we developed a new design for structured applications and selection interviews. The design contains semi-structured interviews, which combine individualised elements from the applications with standardised b...
journal_title:Danish medical journal
pub_type: 杂志文章
doi:
更新日期:2013-09-01 00:00:00